Online signature verification using hybrid wavelet transform

Online signature verification is a prominent behavioral biometric trait. It offers many dynamic features along with static two dimensional signature image. In this paper, the Hybrid Wavelet Transform (HWT) was generated using Kronecker product of two orthogonal transform such as DCT, DHT, Haar, Hadamard and Kekre. HWT has the ability to analyze the signal at global as well as local level like wavelet transform. HWT-1 and -2 was applied on the first 128 samples of the pressure parameter and first 16 samples of the output were used as feature vector for signature verification. This feature vector is given to Left to Right HMM classifier to identify the genuine and forged signature. For HWT-1, DCT HAAR offers best FAR and FRR. . For HWT-2, KEKRE 128 offers best FAR and FRR. HWT-1 offers better performance than HWT- 2 in terms of FAR and FRR. As the number of states increase, the performance of the system improves. For HWT - 1, KEKRE 128 offers best performance at 275 symbols whereas for HWT - 2, best performance is at 475 symbols by KEKRE 128

Entrepreneurial Skill Development through Aonla Processing in Punjab, India

Indian economy is predominantly dependent on agriculture and allied sectors as they are the important source of raw material and demand for many industrial products. As one among the allied sector, food processing sector is nowadays gaining attention amid entrepreneurs across the country. Famer’s interest as an entrepreneur is constantly increasing in terms of investment which creates a promising atmosphere for affluent growth of food processing industry. Ministry of Food Processing Industries, Govt. of India is a wing which is actively engaged in promoting entrepreneurial activities in fruits and vegetables processing sector. However, there exists a definite demand to attract the small and marginal farmers to avail this entrepreneurship facility so that it can help in improving their livelihood and become a source of their family income. This particular case study is a representation of facilities availed by some entrepreneurs in ICAR-CIPHET Abohar for aonla processing. Such kind of information may become a source of encouragement for the farmers who are having a desire to promote themselves as farmer cum businessman.

Development of Single-Phase Microbial Cementation Method and to Investigate its Efficacy on Bearing Capacity, UCS, and Permeability of Sandy Soils

Microbially induced calcite precipitation (MICP) is a method based on collaborative knowledge of microbiology, chemistry and geotechnical engineering. The objective of this study was to investigate the increase of the bearing capacity and the unconfined compressive strength (UCS) as well as the reduction of the permeability of sandy soil using MICP. Experiments were carried out using Bacillus Pasteurii, on three different types of sand. The admixture of bacterial culture and cementation (BCC) solution all-in-one with sand by single-phase injection was applied to induce cementation. Three samples of the selected sand were treated with varied concentrations of BCC solution, ranging from 0.05 to 0.2 L/kg, with a curing period of 3, 7 and 14 days. The test results indicated an enhancement of 55% in UCS for sand treated with a BCC content of 0.05 to 0.2 L/Kg and a reduction of 40% in permeability for untreated sand with an effective diameter of 0.5 mm treated with 0.2 L/kg of BCC solution after 14 days of curing. The results of a plate load test (PLT) on MICP treated sand showed an increase in the ultimate bearing capacity (qu) by about 2.95 to 5.8 times and a 1.7 to 3.31-fold reduction in settlement corresponding to the same load applied on untreated footing. Further investigation of the size and shape of the bearing plate on bearing capacity and settlement was carried out through a plate load test. The higher and more favorable results shown by a rectangular plate compared to a circular plate indicate that the first is preferable

Analyzing Quality of Water in River using IoT

Internet of Things (IoT) is international network of “smart device” which will sense and interrelate with their atmosphere mistreatment the net for his or her communication and interaction with users and different systems. The main conception behind every IoT technology and implementation is “Device is integrated with the virtual world of internet and interacts with it by following, sensing and monitoring object and their environment”. The structures of a “smart device” that may act as a member of IoT network are, collect and transmit knowledge, actuate device supported activates and receive info (from network and internet). Presently in our country, the water analysis is completed manually by taking the samples from the water sources (river) and send to the research lab for study. To mechanize this method, water quality watching sensors, ARM7, are physically placed in each and every water sources (river). The water quality watching sensors gather knowledge from water. The ARM7 forward that knowledge to concentrator module through Wi-Fi module for remote transfer of information to the research lab. The information concentrator that is found in each and every lake, send that knowledge to the cloud organized server that is settled within the testing laboratory. The department workers monitor this data remotely and securely provide this data to the requested users which are stored in the cloud

Techniques used in orally disintegrating drug delivery system

Formulation of a convenient dosage form for administration, by considering swallowing difficulty and poor patient compliance, leads to development of orally disintegrating tablets. This are also called as orodisperse, mouth dissolving, rapidly disintegrating, and fast melt system. This disintegrates in the mouth in seconds without chewing and the need of water which is advantageous mainly for pediatrics, geriatrics and patients having difficulty in swallowing tablets and capsules. Conventional preparation methods are spray drying, freeze drying, direct compression, Molding, and sublimation while new technologies have been developed for the production of orodispersible tablets. This review depicts conventional and recent technologies that are used to prepare orodispersible tablets in detail.Keywords: Orally disintegrating tablet; Superdisintegrant; Patented technologies; Orodispersible tablet

Techniques used in orally disintegrating drug delivery system

Formulation of a convenient dosage form for administration, by considering swallowing difficulty and poor patient compliance, leads to development of orally disintegrating tablets. This are also called as orodisperse, mouth dissolving, rapidly disintegrating, and fast melt system. This disintegrates in the mouth in seconds without chewing and the need of water which is advantageous mainly for pediatrics, geriatrics and patients having difficulty in swallowing tablets and capsules. Conventional preparation methods are spray drying, freeze drying, direct compression, Molding, and sublimation while new technologies have been developed for the production of orodispersible tablets. This review depicts conventional and recent technologies that are used to prepare orodispersible tablets in detail.Keywords: Orally disintegrating tablet; Superdisintegrant; Patented technologies; Orodispersible tablet

Mucin Histochemistry Study of the Prostate in Normal and Malignant Lesions

Background: There is an increase in the incidence of the prostate cancer by 1% yearly which has been recorded in the last three years. Early diagnosis of prostate cancer is important and differentiation between normal and malignant lesions of prostate has been a diagnostic dilemma. There is unavailability of modern techniques in rural areas as well as in developing countries. Aims and Objectives: To evaluate the usefulness of mucin stains in differentiating normal and malignant lesions of prostate. Material and Methods: The study was done on 33 specimens of normal (n=11) and malignant (n=22) prostates which were collected from postmortem and surgically resected specimens in Krishna Institute of Medical Sciences and Krishna Hospital Medical Research Central. Normal prostate specimens were used as controls with carcinoma of prostate as test. The type of study was case control study. Routine Hematoxylin / Eosin and special stains as PAS, PASDiastase, PAS-Phenyl Hydrazine, Alcian Blue pH-2.5 and 1, Aldehyde Fuchsin, combined AB-PAS and AFAB were performed. Results: Results were tabulated according to colour intensity into different grades ranging from -ve to +++. Neutral mucins were observed in normal prostate and in prostate carcinoma acid mucins were seen predominantly present. Conclusion: Mucin histochemistry may provide a valuable and cost effective tool for the diagnostic histopathology of prostate lesions

Identification of CD163 as an antiinflammatory receptor for HMGB1-haptoglobin complexes

Secreted by activated cells or passively released by damaged cells, extracellular HMGB1 is a prototypical damage-associated molecular pattern (DAMP) inflammatory mediator. During the course of developing extracorporeal approaches to treating injury and infection, we inadvertently discovered that haptoglobin, the acute phase protein that binds extracellular hemoglobin and targets cellular uptake through CD163, also binds HMGB1. Haptoglobin-HMGB1 complexes elicit the production of antiinflammatory enzymes (heme oxygenase-1) and cytokines (e.g., IL-10) in WT but not in CD163-deficient macrophages. Genetic disruption of haptoglobin or CD163 expression significantly enhances mortality rates in standardized models of intra-abdominal sepsis in mice. Administration of haptoglobin to WT and to haptoglobin gene-deficient animals confers significant protection. These findings reveal a mechanism for haptoglobin modulation of the inflammatory action of HMGB1, with significant implications for developing experimental strategies targeting HMGB1-dependent inflammatory diseases

Integrating transcriptomic and proteomic data for accurate assembly and annotation of genomes

© 2017 Wong et al.; Published by Cold Spring Harbor Laboratory Press. Complementing genome sequence with deep transcriptome and proteome data could enable more accurate assembly and annotation of newly sequenced genomes. Here, we provide a proof-of-concept of an integrated approach for analysis of the genome and proteome of Anopheles stephensi, which is one of the most important vectors of the malaria parasite. To achieve broad coverage of genes, we carried out transcriptome sequencing and deep proteome profiling of multiple anatomically distinct sites. Based on transcriptomic data alone, we identified and corrected 535 events of incomplete genome assembly involving 1196 scaffolds and 868 protein-coding gene models. This proteogenomic approach enabled us to add 365 genes that were missed during genome annotation and identify 917 gene correction events through discovery of 151 novel exons, 297 protein extensions, 231 exon extensions, 192 novel protein start sites, 19 novel translational frames, 28 events of joining of exons, and 76 events of joining of adjacent genes as a single gene. Incorporation of proteomic evidence allowed us to change the designation of more than 87 predicted noncoding RNAs to conventional mRNAs coded by protein-coding genes. Importantly, extension of the newly corrected genome assemblies and gene models to 15 other newly assembled Anopheline genomes led to the discovery of a large number of apparent discrepancies in assembly and annotation of these genomes. Our data provide a framework for how future genome sequencing efforts should incorporate transcriptomic and proteomic analysis in combination with simultaneous manual curation to achieve near complete assembly and accurate annotation of genomes

Syndrome of right isomerism: Ivemark syndrome

Heterotaxy Syndrome is a complex syndrome that occurs when the axes of the body fail to rotate correctly when developing in the uterus. This can result in many different organ systems being affected. Cardiac malformations are a major component of heterotaxy syndrome, resulting in significant morbidity and mortality. Abnormal cardiac development typically leads to atrial appendage isomerism, resulting in either bilateral paired right atria (right atrial isomerism or paired left atria (left atrial isomerism. Here we present a one and a half-month-old female child with right isomerism