1,046 research outputs found
Spiritual pilgrimage : a study of its sources and thematic significance in the novels of Charlotte Bronte, Elizabeth Gaskell and George Eliot
SIGLEAvailable from British Library Document Supply Centre- DSC:D43491/82 / BLDSC - British Library Document Supply CentreGBUnited Kingdo
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Topology Driven Improvement of FDC Build Parameters
The likeliest failure origin for advanced ceramics parts, prepared by fused
deposition, is a void from improper fill. Adequate filling of each cross-section is dependent upon the deposition toolpath. Cross-sectional spaces are conventionally
filled with pre-defined parameters. We propose that adaptive build parameters will
control variations in geometry and property of a part. Voids, overfilling,
incomplete bonding and excess traversing can be suppressed by adjusting the fill
parameters for cross-sectional areas. Improved build parameters and toolpath
allows for faster build time and components ofj full density. Some implementations
are discussed and presented.Mechanical Engineerin
A Family Strengths Approach to Early Language and Literacy Development
Language and literacy skills are an essential element of young childrenâs development and allow them to interact meaningfully with other people and to develop knowledge in all subject areas. Despite the importance of language and literacy development, however, more than one third of children in the United States enter school with significant differences in language, early literacy skills, and motivation to learn that place them at considerable risk for developing long-term reading difficulties. The quantity and quality of language interactions children have with their parents and exposure to print in their home environment prior to entering school have an important impact on these individual differences. This paper provides teachers with guidelines and tools for helping families identify and create language and literacy opportunities in their home environment that reflect their unique strengths and routines
Diurnal variation of urinary "hCG beta subunit core fragment" production evaluated in patients with gynecological neoplasms
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Determining cooling rates from mica <sup>40</sup>Ar/ <sup>39</sup>Ar thermochronology data: effect of cooling path shape
Tectonic models are commonly underpinned by metamorphic cooling rates derived fromd iffusive-loss thermochronology data. Such cooling agesare usually linked to temperature via Dodsonâs 1973 closure temperature (TC) formulation, which specifies a 1/time shaped cooling path. Geologists, however,commonly discuss cooling rates as a linear temperature/time shape. We present the results of a series of simple finite-difference diffusion models for Ar diffusion in muscovite and biotite that show that the difference in recorded age between 1/t and linear cooling paths increases significantly with hotter starting temperatures, slower cooling rates and smaller grain sizes. Our results show that it is essential to constrain the cooling path shape in order to make meaningful interpretations of the measured data
The prognostic significance of beta human chorionic gonadotrophin and its metabolites in women with cervical carcinoma
AIMS: To examine long term survival of women with primary and recurrent cervical carcinoma in relation to (1) excretion of beta-core (a urinary metabolite of beta human chorionic gonadotrophin (beta hCG)) and (2) beta hCG immunostaining of the tumours, to determine the suitability of these markers for assessing prognosis. METHODS: This was a prospective observational study undertaken in a gynaecological oncology centre: 57 women with primary cervical cancer and 42 with recurrent disease were recruited between January 1990 and September 1992. Kaplan-Meier survival analysis with the log rank test was used to assess survival differences with survival rate given per year of follow up. RESULTS: In primary disease, the four year survival for the beta-core negative group was 79%, compared with 14% for the beta-core positive group (p = 0.001). This was still significant for early stage disease or squamous lesions alone. In recurrent disease, beta-core positivity was not prognostically significant. Immunohistochemistry was of no prognostic significance in either group. CONCLUSIONS: beta-core excretion appears to be useful in assessing prognosis of primary cervical cancer but not of recurrent disease. A large prospective study of urinary beta-core in early stage cervical cancer is needed to determine whether it can be used as an index for modifying treatment
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