Application of Correspondence Analysis to Graphically Investigate Associations Between Foods and Eating Locations.

This paper presents the application of correspondence analysis (CA) for investigating associations using confidence regions (CRs) with a focus on facilitating mining the data and hypothesis generation. We study the relationship between locations and "less-healthy" food consumption by UK teenagers. CA allows for a quick visual inspection of the various association structures that exist between the categories of cross-classified variables in large datasets derived with varying study designs. The hypotheses generated by the visual display can then be independently tested using suitable regression models. CA makes use of readily available software tools and of robust statistical tests amenable to interpretation

Application of correspondence analysis to graphically investigate associations between foods and eating locations

This paper presents the application of correspondence analysis (CA) for investigating associations using confidence regions (CRs) with a focus on facilitating mining the data and hypothesis generation. We study the relationship between locations and “less-healthy” food consumption by UK teenagers. CA allows for a quick visual inspection of the various association structures that exist between the categories of cross-classified variables in large datasets derived with varying study designs. The hypotheses generated by the visual display can then be independently tested using suitable regression models. CA makes use of readily available software tools and of robust statistical tests amenable to interpretation

Development of a time-to-digital converter ASIC for the upgrade of the ATLAS Monitored Drift Tube detector

The upgrade of the ATLAS muon spectrometer for high-luminosity LHC requires new trigger and readout electronics for the various elements of the detector. We present the design of a time-to-digital converter (TDC) ASIC prototype for the ATLAS Monitored Drift Tube (MDT) detector. The chip was fabricated in a GlobalFoundries 130 nm CMOS technology. Studies indicate that its timing and power consumption characteristics meet the design specifications, with a timing bin variation of 40 ps for all 48 channels with a power consumption of about 6.5 mW per channel.Comment: 9 pages, 12 figure

Assessing and mitigating impacts of motorboat noise on nesting damselfish

This is the final version. Available on open access from Elsevier via the DOI in this recordMotorboats are a pervasive, growing source of anthropogenic noise in marine environments, with known impacts on fish physiology and behaviour. However, empirical evidence for the disruption of parental care remains scarce and stems predominantly from playback studies. Additionally, there is a paucity of experimental studies examining noise-mitigation strategies. We conducted two field experiments to investigate the effects of noise from real motorboats on the parental-care behaviours of a common coral-reef fish, the Ambon damselfish Pomacentrus amboinensis, which exhibits male-only egg care. When exposed to motorboat noise, we found that males exhibited vigilance behaviour 34% more often and spent 17% more time remaining vigilant, compared to an ambient-sound control. We then investigated nest defence in the presence of an introduced conspecific male intruder, incorporating a third noise treatment of altered motorboat-driving practice that was designed to mitigate noise exposure via speed and distance limitations. The males spent 22% less time interacting with the intruder and 154% more time sheltering during normal motorboat exposure compared to the ambient-sound control, with nest-defence levels in the mitigation treatment equivalent to those in ambient conditions. Our results reveal detrimental impacts of real motorboat noise on some aspects of parental care in fish, and successfully demonstrate the positive effects of an affordable, easily implemented mitigation strategy. We strongly advocate the integration of mitigation strategies into future experiments in this field, and the application of evidence-based policy in our increasingly noisy world.Natural Environment Research Council (NERC)Australian Research Council (ARC)University of ExeterSwiss National Science Foundatio

Enhancing Trial Delivery in Parkinson\u27s Disease: Qualitative Insights from PD STAT

\ua9 2022 - The authors. Published by IOS Press. Background: Recruitment and retention of participants in clinical trials for Parkinson\u27s disease (PD) is challenging. A qualitative study embedded in the PD STAT multi-centre randomised controlled trial of simvastatin for neuroprotection in PD explored the motivators, barriers and challenges of participants, care partners and research staff. Objective: To outline a set of considerations informing a patient-centred approach to trial recruitment, retention, and delivery. Method: We performed semi-structured interviews and focus groups with a subset of trial participants and their care partners. Quantitative and qualitative data were obtained through surveys circulated among the 235 participants across 23 UK sites at the beginning, middle and end of the 2-year trial. We also interviewed and surveyed research staff at trial closure. Results: Twenty-seven people with PD, 6 care partners and 9 researchers participated in interviews and focus groups. A total of 463 trial participant survey datasets were obtained across three timepoints, and 53 staff survey datasets at trial closure. Trial participants discussed the physical and psychological challenges they faced, especially in the context of OFF state assessments, relationships, and communication with research staff. Care partners shared their insights into OFF state challenges, and the value of being heard by research teams. Research staff echoed many concerns with suggestions on flexible, person-centred approaches to maximising convenience, comfort, and privacy. Conclusion: These considerations, in favour of person-centred research protocols informed by the variable needs of participants, care partners and staff, could be developed into a set of recommendations for future trials

Economic impact of frost in the Australian wheatbelt

[Introduction]: Extreme temperatures can cause severe reductions in wheat yield, including in Australia where temperatures are highly variable within and across growing seasons. A single post head-emergence frost (PHEF) event has the potential to devastate individual wheat crop by damaging stems and killing whole head. Management of crop phenology to avoid PHEF is very important in many parts of the world where frost risk is high. Breeding for improved reproductive frost tolerance could allow greater yield and economic benefits to be achieved, by (i) reducing direct frost damage and (ii) allowing earlier sowing to reduce risks of late-season drought and/or heat stresses (Fig. 1). This study aims to provides insights into the frost impact and economic benefits of different improved frost tolerance levels across the Australian wheatbelt

The influence of the atmospheric boundary layer on nocturnal layers of noctuids and other moths migrating over southern Britain

Insects migrating at high altitude over southern Britain have been continuously monitored by automatically-operating, vertical-looking radars over a period of several years. During some occasions in the summer months, the migrants were observed to form well-defined layer concentrations, typically at heights of 200-400 m, in the stable night-time atmosphere. Under these conditions, insects are likely to have control over their vertical movements and are selecting flight heights which are favourable for long-range migration. We therefore investigated the factors influencing the formation of these insect layers by comparing radar measurements of the vertical distribution of insect density with meteorological profiles generated by the UK Met. Office’s Unified Model (UM). Radar-derived measurements of mass and displacement speed, along with data from Rothamsted Insect Survey light traps provided information on the identity of the migrants. We present here three case studies where noctuid and pyralid moths contributed substantially to the observed layers. The major meteorological factors influencing the layer concentrations appeared to be: (a) the altitude of the warmest air, (b) heights corresponding to temperature preferences or thresholds for sustained migration and (c), on nights when air temperatures are relatively high, wind-speed maxima associated with the nocturnal jet. Back-trajectories indicated that layer duration may have been determined by the distance to the coast. Overall, the unique combination of meteorological data from the UM and insect data from entomological radar described here show considerable promise for systematic studies of high-altitude insect layering

Long-term controls on continental-scale bedrock river terrace deposition from integrated clast and heavy mineral assemblage analysis: an example from the lower Orange River, Namibia

Establishing relationships between the long-term landscape evolution of drainage basins and the fill of sedimentary basins benefits from analysis of bedrock river terrace deposits. These fragmented detrital archives help to constrain changes in river system character and provenance during sediment transfer from continents (source) to oceans (sink). Thick diamondiferous gravel terrace deposits along the lower Orange River, southern Namibia, provide a rare opportunity to investigate controls on the incision history of a continental-scale bedrock river. Clast assemblage and heavy mineral data from seven localities permit detailed characterisation of the lower Orange River gravel terrace deposits. Two distinct fining-upward gravel terrace deposits are recognised, primarily based on mapped stratigraphic relationships (cross-cutting relationships) and strath and terrace top elevations, and secondarily on the proportion of exotic clasts, referred to as Proto Orange River deposits and Meso Orange River deposits. The older early to middle Miocene Proto Orange River gravels are thick (up to 50 m) and characterised by a dominance of Karoo Supergroup shale and sandstone clasts, whereas the younger Plio-Pleistocene Meso Orange River gravels (6–23 m thick) are characterised by more banded iron formation clasts. Mapping of the downstepping terraces indicates that the Proto gravels were deposited by a higher sinuosity river, and are strongly discordant to the modern Orange River course, whereas the Meso deposits were deposited by a lower sinuosity river. The heavy minerals present in both units comprise magnetite, garnet, amphibole, epidote and ilmenite, with rare titanite and zircon grains. The concentration of amphibole-epidote in the heavy minerals fraction increases from the Proto to the Meso deposits. The decrease in incision depths, recorded by deposit thicknesses above strath terraces, and the differences in clast character (size and roundness) and type between the two units, are ascribed to a more powerful river system during Proto-Orange River time, rather than reworking of older deposits, changes in provenance or climatic variations. In addition, from Proto- to Meso-Orange River times there was an increase in the proportion of sediments supplied from local bedrock sources, including amphibole-epidote in the heavy mineral assemblages derived from the Namaqua Metamorphic Complex. This integrated study demonstrates that clast assemblages are not a proxy for the character of the matrix, and vice versa, because they are influenced by the interplay of different controls. Therefore, an integrated approach is needed to improve prediction of placer mineral deposits in river gravels, and their distribution in coeval deposits downstream