Experiencia en el uso del asistente matemático derive, en la solución de problemas físicos y/o geométricos

En este trabajo se tratarán problemas, en los cuales se tendrá en cuenta el aspecto de modelación, resolución e interpretación de resultados, donde predomina el análisis geométrico en cada situación. La obtención de estos resultados será sobre la base de la aplicación de las nuevas tecnologías, que favorecen el aprendizaje del estudiante y estimulan los procesos de creación y abstracción, permitiendo realizar operaciones con rapidez y exactitud. Además facilitan el intercambio ágil de información con el ordenador, aprovechando las capacidades tanto simbólicas como gráficas de los Asistentes Matemáticos (en este caso DERIVE)

Exchanging screen for non-screen sitting time or physical activity might attenuate depression and anxiety: A cross-sectional isotemporal analysis during early pandemics in South America

Objectives: To examine the theoretical substitutions of screen exposure, non-screen sitting time, moderate and vigorous physical activity with depressive and anxiety symptoms in South American adults during the COVID-19 pandemic. Design: A cross-sectional study during the first months of the COVID-19 pandemic with data from 1981 adults from Chile, Argentina, and Brazil. Methods: Depressive and anxiety symptoms were assessed using the Beck Depression and Anxiety Inventories. Participants also reported physical activity, sitting time, screen exposure, sociodemographic, and tobacco use data. Isotemporal substitution models were created using multivariable linear regression methods. Results: Vigorous physical activity, moderate physical activity, and screen exposure were independently associated with depression and anxiety symptoms. In adjusted isotemporal substitution models, replacing 10 min/day of either screen exposure or non-screen sitting time with any intensity of physical activity was associated with lower levels of depressive symptoms. Improvements in anxiety symptoms were found when reallocating either screen exposure or non-screen sitting time to moderate physical activity. Furthermore, replacing 10 min/day of screen exposure with non-screen sitting time was beneficially associated with anxiety (B = − 0.033; 95 % CI = − 0.059, − 0.006) and depression (B = − 0.026; 95 % CI = − 0.050, − 0.002). Conclusions: Replacement of screen exposure with any intensity of physical activity or non-screen sitting time could improve mental health symptoms. Strategies aiming to reduce depressive and anxiety symptoms highlight physical activity promotion. However, future interventions should explore specific sedentary behaviors as some will relate positively while others negatively.Fil: Sadarangani, Kabir P.. Universidad Autónoma de Chile; Chile. Universidad Diego Portales; ChileFil: Schuch, Felipe Barreto. Universidade Federal de Santa Maria; Brasil. Universidad Autónoma de Chile; ChileFil: de Roia, Gabriela Fernanda. Universidad de Flores. Laboratorio de Estudios en Actividad Física;Fil: Martínez Gomez, David. Universidad Autónoma de Madrid; España. Consejo Superior de Investigaciones Científicas; España. Consortium for Biomedical Research in Epidemiology and Public Health; EspañaFil: Chávez, Róbinson. Universidad Andrés Bello; ChileFil: Lobo, Pablo Roberto. Universidad de Flores. Laboratorio de Estudios en Actividad Física;Fil: Cristi Montero, Carlos. Pontificia Universidad Católica de Valparaíso; ChileFil: Werneck, André O.. Universidade de Sao Paulo; BrasilFil: Alzahrani, Hosam. Taif University; Arabia SauditaFil: Ferrari, Gerson. Universidad de Santiago de Chile; ChileFil: Ibañez, Agustin Mariano. Universidad de San Andrés; Argentina. University of California; Estados Unidos. Trinity College Dublin; Irlanda. Universidad Adolfo Ibañez; Chile. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Silva, Danilo R.. Universidade Federal de Sergipe; Brasil. Universidad Pablo de Olavide; EspañaFil: Von Oetinger, Astrid. Universidad Diego Portales; Chile. Universidad Mayor; ChileFil: Matias, Thiago S.. Universidade Federal de Santa Catarina; BrasilFil: Grabovac, Igor. Universidad de Viena; AustriaFil: Meyer, Jacob. Iowa State University; Estados Unido

Mineralogy, geochemistry and sulfur isotope characterization of Cerro de Maimón (Dominican Republic), San Fernando and Antonio (Cuba) lower Cretaceous VMS deposits: Formation during subduction initiation of the proto-Caribbean lithosphere within a fore-arc

The volcanic-arc Lower Cretaceous Maimón (Dominican Republic) and Los Pasos (Cuba) Formations, representative of the oldest magmatism recorded in the Caribbean island arc, host most of the known volcanogenic massive sulfide (VMS) deposits in the Greater Antilles. On the basis of new lithogeochemical data, basalts of the Maimón Formation are classified as fore arc basalts (FAB), boninites and less abundant low-Ti (LOTI) and normal island-arc tholeiites (IAT), and those of the Los Pasos Formation as LOTI and IAT. Felsic volcanics from the two formations are geochemically analogous and present mantle-type (M-type), boninitic and tholeiitic signatures, classifying as FIV-type, typical of post-Archaean VMS-bearing juvenile volcanic suites. This lithogeochemical data is indicative of formation in a fore-arc environment just after subduction initiation in association with initial extensional regimes and associated boninitic and tholeiitic melts that originated in the shallow mantle. Within this tectonic framework, rocks of the Los Pasos Formation and associated VMS deposits likely formed at a slightly later stage than those of the Maimón Formatio

La geoquímica de la Formación Maimón (Cordillera Central, República Dominicana) revisada

Los materiales volcánicos de la Formación Maimón, metamorfizados en facies de esquistos verdes, son representativos del magmatismo más antiguo registrado en el arco-isla del Cretácico del Caribe. A partir de nuevos datos geoquímicos de roca total y mediante el uso de elementos traza inmóviles (elementos de alto potencial iónico - HFSE, tierras raras - REE), se reconoce el predominio de protolitos basálticos y una menor proporción de rocas de composición intermedia y ácida. Geoquímicamente, los protolitos basálticos han sido clasificados como boninitas, toleítas de arco de isla pobres en Ti y LREE, toleítas de arco de isla pobres en Ti normales y escasas toleítas de arco de isla normales. Las rocas ácidas presentan claras afinidades boniníticas y toleíticas y pertenecerían al tipo M (derivadas del manto). La geoquímica de las toleítas pobres en Ti y LREE permite su clasificación como FAB (Fore-Arc Basalts, i.e. basaltos de ante-arco), término recientemente acuñado para describir toleítas con rasgos de MORB (basaltos de dorsal centro-oceánica) identificados en el ante-arco de Izu-Bonin-Mariana. La presencia de FAB y su correlación estratigráfica con boninitas son indicativas de formación en un contexto de ante-arco durante los primeros estadios magmáticos en un régimen extensional ligado al inicio de la subducción y el nacimiento del arco-isla. La Fm. Maimón puede representar la sección superior (volcánica) de una ofiolita tipo "inicio de subducción"

Latin American anaphylaxis registry

Background: Recent data about clinical features, triggers and management of anaphylaxis in Latin America is lacking. Objective: To provide updated and extended data on anaphylaxis in this region. Method: An online questionnaire was used, with 67 allergy units involved from 12 Latin-American countries and Spain. Among data recorded, demographic information, clinical features, severity, triggering agents, and treatment were received. Results: Eight hundred and seventeen anaphylactic reactions were recorded. No difference in severity, regardless of pre-existing allergy or asthma history was found. Drug induced anaphylaxis (DIA) was most frequent (40.6%), followed by food induced anaphylaxis (FIA) (32.9%) and venom induced anaphylaxis (VIA) (12%). FIA and VIA were more common in children-adolescents. Non-steroidal anti-inflammatory drugs (NSAIDs) and beta-lactam antibiotics (BLA) were the most frequent drugs involved. Milk (61.1% of FIA) and egg (15.4% of FIA) in children, and shellfish (25.5% of FIA), fresh fruits (14.2% of FIA), and fish (11.3% of FIA) in adults were the most common FIA triggers. Fire ants were the most frequent insect triggers, and they induced more severe reactions than triggers of FIA and DIA (p < 0.0001). Epinephrine was used in 43.8% of anaphylaxis episodes. After Emergency Department treatment, epinephrine was prescribed to 13% of patients. Conclusions: Drugs (NSAIDs and BLA), foods (milk and egg in children and shellfish, fruits and fish in adults) and fire ants were the most common inducers of anaphylaxis. Epinephrine was used in less than half of the episodes emphasizing the urgent need to improve dissemination and implementation of anaphylaxis guidelines.Revisión por pare

Ten simple rules to host an inclusive conference.

Conferences are spaces to meet and network within and across academic and technical fields, learn about new advances, and share our work. They can help define career paths and create long-lasting collaborations and opportunities. However, these opportunities are not equal for all. This article introduces 10 simple rules to host an inclusive conference based on the authors' recent experience organizing the 2021 edition of the useR! statistical computing conference, which attracted a broad range of participants from academia, industry, government, and the nonprofit sector. Coming from different backgrounds, career stages, and even continents, we embraced the challenge of organizing a high-quality virtual conference in the context of the Coronavirus Disease 2019 (COVID-19) pandemic and making it a kind, inclusive, and accessible experience for as many people as possible. The rules result from our lessons learned before, during, and after the organization of the conference. They have been written mainly for potential organizers and selection committees of conferences and contain multiple practical tips to help a variety of events become more accessible and inclusive. We see this as a starting point for conversations and efforts towards building more inclusive conferences across the world. * Translated versions of the English abstract and the list of rules are available in 10 languages in S1 Text: Arabic, French, German, Italian, Japanese, Korean, Portuguese, Spanish, Tamil, and Thai

Clonal chromosomal mosaicism and loss of chromosome Y in elderly men increase vulnerability for SARS-CoV-2

The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, COVID-19) had an estimated overall case fatality ratio of 1.38% (pre-vaccination), being 53% higher in males and increasing exponentially with age. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, we found 133 cases (1.42%) with detectable clonal mosaicism for chromosome alterations (mCA) and 226 males (5.08%) with acquired loss of chromosome Y (LOY). Individuals with clonal mosaic events (mCA and/or LOY) showed a 54% increase in the risk of COVID-19 lethality. LOY is associated with transcriptomic biomarkers of immune dysfunction, pro-coagulation activity and cardiovascular risk. Interferon-induced genes involved in the initial immune response to SARS-CoV-2 are also down-regulated in LOY. Thus, mCA and LOY underlie at least part of the sex-biased severity and mortality of COVID-19 in aging patients. Given its potential therapeutic and prognostic relevance, evaluation of clonal mosaicism should be implemented as biomarker of COVID-19 severity in elderly people. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, individuals with clonal mosaic events (clonal mosaicism for chromosome alterations and/or loss of chromosome Y) showed an increased risk of COVID-19 lethality

4to. Congreso Internacional de Ciencia, Tecnología e Innovación para la Sociedad. Memoria académica

Este volumen acoge la memoria académica de la Cuarta edición del Congreso Internacional de Ciencia, Tecnología e Innovación para la Sociedad, CITIS 2017, desarrollado entre el 29 de noviembre y el 1 de diciembre de 2017 y organizado por la Universidad Politécnica Salesiana (UPS) en su sede de Guayaquil. El Congreso ofreció un espacio para la presentación, difusión e intercambio de importantes investigaciones nacionales e internacionales ante la comunidad universitaria que se dio cita en el encuentro. El uso de herramientas tecnológicas para la gestión de los trabajos de investigación como la plataforma Open Conference Systems y la web de presentación del Congreso http://citis.blog.ups.edu.ec/, hicieron de CITIS 2017 un verdadero referente entre los congresos que se desarrollaron en el país. La preocupación de nuestra Universidad, de presentar espacios que ayuden a generar nuevos y mejores cambios en la dimensión humana y social de nuestro entorno, hace que se persiga en cada edición del evento la presentación de trabajos con calidad creciente en cuanto a su producción científica. Quienes estuvimos al frente de la organización, dejamos plasmado en estas memorias académicas el intenso y prolífico trabajo de los días de realización del Congreso Internacional de Ciencia, Tecnología e Innovación para la Sociedad al alcance de todos y todas