Response of the aging eye to first day of modern material contact lens wear

Objectives: To investigate the ocular surface of an aged population wearing a daily disposable contact lens over their first day of wear. Methods: Forty eyes from forty presbyopic subjects were fitted a daily CL (Delefilcon A). Tear osmolarity, tear meniscus area (TMA) and ocular surface aberrations (total higher order root means square (RMS)) were assessed at baseline (t0), at 20 minutes (t1) and after 8 hours (t2) of wear. Fluorescein corneal and conjunctival staining and tear break up time (TBUT) were performed at t0 and t2. Results: No statistically significant changes were found between t0, t1 and t2 for TMA, and between t0 and t2 for fluorescein corneal and conjunctival staining. TBUT worsened by the end of the day from 10.4±0.4 seconds t0 to 9.0±0.3 seconds t2 (P <0.05). Osmolarity showed significant changes between t0 306.9±2.3 mOsm/L and t1 312.4±2.4 mOsmol/L (P = 0.02), but returned to baseline values at 8 hours (310.40±2.26 mOsm/L; P = 0.09). Total higher order root means square (RMS) showed significant changes between t0 0.38±0.02 μm and t1 0.61±0.04 μm (P ≤ 0.001) and between t0 and t2 0.64±0.41 μm (P ≤ 0.001). Conclusions: Delefilcon A may induce measures changes (osmolarity and TBUT values) in a presbyopic population, however TMA and vital staining were maintained at the baseline level over the day

Regresión del defecto campimétrico en un paciente con glaucoma primario de ángulo abierto

Pocos estudios han podido demostrar la mejoría del campo visual tras una pérdida de sensibilidad de origen glaucomatoso. En la mayoría de ellos, las recuperaciones campimétricas se producían al comienzo del tratamiento hipotensor; y, en menos casos, fueron progresivas y/o evolucionaron en varios años. Se presenta el caso de un paciente de 46 años al que, en septiembre 1995, se diagnosticó glaucoma primario de ángulo abierto, siendo tratado con carteolol 2%. El seguimiento durante 7 años puso de manifiesto un importante grado de regresión de los defectos campimétricos, mostrando la importancia de la campimetría computarizada en el diagnóstico precoz y seguimiento del glaucoma.Just a few studies could demonstrate the improvement of the visual fields after a glaucoma-induced sensitive loss. In most of them, perimetric recoveries arose at the beginning of the hypotensor treatment and, in less cases, were progressive and/or evolved during several years. A case is presented involving a 46 years old patient who, in September 1995, was diagnosed of open angle primary glaucoma, being treated with carteolol 2%. Follow-up visits for 7 years showed certain degree of regression of the perimetric defects, showing the relevance of the automated perimetry in the early glaucoma diagnosis and follow-up examination