MOOC " La Renaissance en Val de Loire" - Épisode 7 « Musique »

Partenaires : Université de Tours/CNRS – Support de médiation développé avec la contribution de Vlam! Productions, dans le cadre du programme ARD Intelligence des Patrimoines financé par la Région Centre-Val de Loire – Cette opération est cofinancée par l’Union européenne. L’Europe s’engage en région Centre-Val de Loire avec le Fonds Européen de Développement Régional (Projet FEDER 2018-2021) Benoist Pierre (dir.) avec la collaboration de Morgane Chaumier, Ivana Cernanova, Carole Jolly, dir. Musicale : Daniel Saulnier et Camilla Cavicchi, Université de Tours, 2021.MOOC (cours en ligne interactif) interdisciplinaires sur " La Renaissance en Val de Loire" – Épisode 7 « Musique » , responsable scientifique : Daniel Saulnier - (Durée 44.mn) Tournages les 24 et 25 septembre 2019, puis le 23 juin 2020, au château de Montreuil-Bellay et sa chapelle privée (accueillis par Madame de Valbray dont la famille est propriétaire du château), à la Tour Charlemagne de Tours, ainsi que dans les locaux du CESR de Tours (Centre d’Etudes Supérieures de la Renaissance

No relationship between red blood cell distribution width and microcirculatory alterations in septic patients

BACKGROUND: Increased red cell distribution width (RDW), a quantitative measure of erythrocyte size variability, has been associated with increased mortality in critically ill patients. METHODS: In this post-hoc analysis of prospectively collected data, we studied 122 septic patients with and without shock who had undergone sublingual microcirculatory assessment using Sidestream Dark Field (SDF) videomicroscopy. Patient demographics, comorbidities, the Acute Physiology and Chronic Health Evaluation (APACHE) II score on admission and the Sequential Organ Failure Assessment (SOFA) score on the day of the microcirculatory assessment were collected. The RDW was retrospectively collected on the day of the microcirculatory evaluation from the routine daily blood count analysis. RESULTS: Median patient age was 68[55-77] years, and median APACHE II and SOFA scores were 22[17-28] and 10[8-12], respectively; ICU mortality was 43. On the day of the microcirculatory analysis, the median RDW was 13.8[12.8-15.5] and was elevated (>13.4) in 74 (61) patients. There was no correlation between RDW and microcirculatory parameters (functional capillary density, r2 = 0.12; proportion of small perfused vessels, r2 = 0.17; mean flow index, r2 = 0.14). RDW was not related to disease severity, the presence of shock or survival. CONCLUSIONS: RDW is not associated with microcirculatory alterations or prognosis in septic patients.SCOPUS: ar.jinfo:eu-repo/semantics/publishe

Structural assessment of masonry arch bridges by combination of non-destructive testing techniques and three-dimensional numerical modelling: Application to Vilanova bridge

In this work a multidisciplinary approach for the structural assessment of masonry arch bridges is presented. The Vilanova Bridge, located in Galicia, northwest of Spain, is considered for the implementation of the methodology. A comprehensive field survey fully based on non-destructive testing techniques, which integrates laser scanning, ground penetration radar, sonic tests and ambient vibration testing, is proposed. It provides all the necessary geometric data to build an accurate and detailed three-dimensional finite element model. The calibration of the model is then carried out through the coupling with an optimization algorithm, which minimizes the discrepancies with respect to the experimentally obtained modal properties. The structural analysis of the bridge is addressed in the last stage. A sensitivity analysis involving different loading scenarios and the plausible variation of the masonry and soil material properties is performed. The results demonstrate the significant influence of tensile non-linear properties of masonry, but also the key role played by fill materials on the arch bridge performance. Lastly, the advantages of adopting a three-dimensional modelling approach are also pointed out, since the apparition of critical transverse effects in the response of the structure is successfully captured by the developed numerical model.This work has been partially supported by the Spanish Ministry of Economy and Competitiveness through the project "HERMES-S3D: Healthy and Efficient Routes in Massive Open-Data based Smart Cities (Ref.: TIN2013-46801-C4-4-R), and by FEDER funds through the Competitiveness Factors Operational Programme - COMPETE and by national funds through FCT - Foundation for Science and Technology within the scope of the project POCI-01-0145-FEDER-007633.info:eu-repo/semantics/publishedVersio