The Evolution of Luminous Compact Blue Galaxies: Disks or Spheroids?

Luminous compact blue galaxies (LCBGs) are a diverse class of galaxies characterized by high luminosity, blue color, and high surface brightness that sit at the critical juncture of galaxies evolving from the blue to the red sequence. As part of our multi-wavelength survey of local LCBGs, we have been studying the HI content of these galaxies using both single-dish telescopes and interferometers. Our goals are to determine if single-dish HI observations represent a true measure of the dynamical mass of LCBGs and to look for signatures of recent interactions that may be triggering star formation in LCBGs. Our data show that while some LCBGs are undergoing interactions, many appear isolated. While all LCBGs contain HI and show signatures of rotation, the population does not lie on the Tully-Fisher relation nor can it evolve onto it. Furthermore, the HI maps of many LCBGs show signatures of dynamically hot components, suggesting that we are seeing the formation of a thick disk or spheroid in at least some LCBGs. There is good agreement between the HI and H-alpha kinematics for LCBGs, and both are similar in appearance to the H-alpha kinematics of high redshift star-forming galaxies. Our combined data suggest that star formation in LCBGs is primarily quenched by virial heating, consistent with model predictions.Comment: 4 pages, 2 figures, to appear in the proceedings of IAU Symposium 277, "Tracing the Ancestry of Galaxies on the Land of our Ancestors", eds. C. Carignan, K.C. Freeman, and F. Combe

Gas flows around 2 young stellar clusters in NGC2264

Observations of the dust and gas toward two young stellar clusters, IRS1 and IRS2, in the NGC2264 star forming region are presented. Continuum emission is used to locate the dusty envelopes around the clusters and individual protostars within and line emission from the J=3-2 transitions of HCO+ and H13CO+ is used to diagnose the gas flows around them. The molecular abundance, velocity centroid and dispersion are approximately constant across the IRS1 clump. With these constraints, the self-absorbed HCO+ lines are modeled as a large scale collapse, with speed v_in=0.3 km/s and mass infall rate dM/dt=4e-4 Msun/yr, falling onto an expanding central core. The signature of large scale collapse, with a similar speed and mass infall rate, is also found toward IRS2 but again appears disrupted at small scales. Individual protostars are resolved in this cluster and their size and velocity dispersion show that the stellar system is currently bound and no older than 0.5 Myr, but is destined to become unbound and disperse as the surrounding cloud material is lost.Comment: 13 page, 6 figures (4 color); accepted for publication in the Ap

Warm Molecular Hydrogen Emission in Normal Edge-On Galaxies NGC 4565 and NGC 5907

We have observed warm molecular hydrogen in two nearby edge-on disk galaxies, NGC 4565 and NGC 5907, using the Spitzer high-resolution infrared spectrograph. The 0-0 S(0) 28.2 micron and 0-0 S(1) 17.0 micron pure rotational lines were detected out to 10 kpc from the center of each galaxy on both sides of the major axis, and in NGC 4565 the S(0) line was detected at r = 15 kpc on one side. This location lies beyond a steep drop in the radio continuum emission from cosmic rays in the disk. Despite indications that star formation activity decreases with radius, the H2 excitation temperature and the ratio of the H2 line and the far-IR luminosity surface densities, Sigma_L(H2}/Sigma_L(TIR}, change very little as a function of radius, even into the diffuse outer region of the disk of NGC 4565. This suggests that the source of excitation of the H2 operates over a large range of radii, and is broadly independent of the strength and relative location of UV emission from young stars. Although excitation in photodissociation regions is the most common explanation for the widespread H2 emission, cosmic ray heating or shocks cannot be ruled out. The inferred mass surface densities of warm molecular hydrogen in both edge-on galaxies differ substantially, being 4(-60) M_solar/pc^2 and 3(-50) M_solar/pc^2 at r = 10 kpc for NGC 4565 and NGC 5907, respectively. The higher values represent very unlikely point-source upper limits. The point source case is not supported by the observed emission distribution in the spectral slits. These mass surface densities cannot support the observed rotation velocities in excess of 200 km/s. Therefore, warm molecular hydrogen cannot account for dark matter in these disk galaxies, contrary to what was implied by a previous ISO study of the nearby edge-on galaxy NGC 891.Comment: Accepted for publication in the Astronomical Journal (20 pages, 17 figures, 7 tables

Quantitative Trait Loci Associated with Milling and Baking Quality in a Soft X Hard Wheat Cross

Interclass hybridization between soft and hard wheat (Triticum aestivum L.) results in new genetic combinations of potential value

The role of micro-organisms (Staphylococcus aureus and Candida albicans) in the pathogenesis of breast pain and infection in lactating women: study protocol

Background: The CASTLE (Candida and Staphylococcus Transmission: Longitudinal Evaluation) study will investigate the micro-organisms involved in the development of mastitis and &ldquo;breast thrush&rdquo; among breastfeeding women. To date, the organism(s) associated with the development of breast thrush have not been identified. The CASTLE study will also investigate the impact of physical health problems and breastfeeding problems on maternal psychological health in the early postpartum period.Methods/Design: The CASTLE study is a longitudinal descriptive study designed to investigate the role of Staphylococcus spp (species) and Candida spp in breast pain and infection among lactating women, and to describe the transmission dynamics of S. aureus and Candida spp between mother and infant. The relationship between breastfeeding and postpartum health problems as well as maternal psychological well-being is also being investigated. A prospective cohort of four hundred nulliparous women who are at least thirty six weeks gestation pregnant are being recruited from two hospitals in Melbourne, Australia (November 2009 to June 2011). At recruitment, nasal, nipple (both breasts) and vaginal swabs are taken and participants complete a questionnaire asking about previous known staphylococcal and candidal infections. Following the birth, participants are followed-up six times: in hospital and then at home weekly until four weeks postpartum. Participants complete a questionnaire at each time points to collect information about breastfeeding problems and postpartum health problems. Nasal and nipple swabs and breast milk samples are collected from the mother. Oral and nasal swabs are collected from the baby. A telephone interview is conducted at eight weeks postpartum to collect information about postpartum health problems and breastfeeding problems, such as mastitis and nipple and breast pain.Discussion: This study is the first longitudinal study of the role of both staphylococcal and candidal colonisation in breast infections and will help to resolve the current controversy about which is the primary organism in the condition known as breast thrush. This study will also document transmission dynamics of S. aureus and Candida spp between mother and infant. In addition, CASTLE will investigate the impact of common maternal physical health symptoms and the effect of breastfeeding problems on maternal psychological well-being.<br /

Failed Labor Induction Toward an Objective Diagnosis

To evaluate maternal and perinatal outcomes in women undergoing labor induction with an unfavorable cervix according to duration of oxytocin administration in the latent phase of labor after ruptured membranes

The Utility of Uterine Artery Doppler Velocimetry in Prediction of Preeclampsia in a Low-Risk Population:

The underlying pathophysiology of preeclampsia is thought to be abnormal trophoblast invasion of the spiral arteries, leading to maldevelopment of uteroplacental perfusion. We estimated whether uterine artery Doppler measurements made in the early second trimester would predict the subsequent development of preeclampsia

Preclinical Alzheimer's disease and longitudinal driving decline

Introduction: Links between preclinical Alzheimer's disease (AD) and driving difficulty onset would support the use of driving performance as an outcome in primary and secondary prevention trials among older adults (OAs). We examined whether AD biomarkers predicted the onset of driving difficulties among OAs. Methods: One hundred four OAs (65+ years) with normal cognition took part in biomarker measurements, a road test, clinical and psychometric batteries, and self-reported their driving habits. Results: Higher values of cerebrospinal fluid (CSF) tau/Aβ42 and phosphorylated tau (ptau181)/Aβ42 ratios, but not uptake on Pittsburgh compound B amyloid imaging (P = .12), predicted time to a rating of marginal or fail on the driving test using Cox proportional hazards models. Hazards ratios (95% confidence interval) were 5.75 (1.70–19.53), P = .005 for CSF tau/Aβ42; 6.19 (1.75–21.88), and P = .005 for CSF ptau181/Aβ42. Discussion Preclinical AD predicted time to receiving a marginal or fail rating on an on-road driving test. Driving performance shows promise as a functional outcome in AD prevention trials

Non-nociceptive roles of opioids in the CNS: opioids' effects on neurogenesis, learning, memory and affect.

Mortality due to opioid use has grown to the point where, for the first time in history, opioid-related deaths exceed those caused by car accidents in many states in the United States. Changes in the prescribing of opioids for pain and the illicit use of fentanyl (and derivatives) have contributed to the current epidemic. Less known is the impact of opioids on hippocampal neurogenesis, the functional manipulation of which may improve the deleterious effects of opioid use. We provide new insights into how the dysregulation of neurogenesis by opioids can modify learning and affect, mood and emotions, processes that have been well accepted to motivate addictive behaviours

Vitamins C and E to Prevent Complications of Pregnancy-Associated Hypertension

Oxidative stress has been proposed as a mechanism linking the poor placental perfusion characteristic of preeclampsia with the clinical manifestations of the disorder. We assessed the effects of antioxidant supplementation with vitamins C and E, initiated early in pregnancy, on the risk of serious adverse maternal, fetal, and neonatal outcomes related to pregnancy-associated hypertension