Probing Mechanical and Chemical Instabilities in Neutron-Rich Matter

The isospin-dependence of mechanical and chemical instabilities is investigated within a thermal and nuclear transport model using a Skyrme-type phenomenological equation of state for neutron-rich matter. Respective roles of the nuclear mean field and the 2-body stochastic scattering on the evolution of density and isospin fluctuations in either mechanically or chemically unstable regions of neutron-rich matter are investigated. It is found that the mean field dominates overwhelmingly the fast growth of both fluctuations, while the 2-body scattering influences significantly the later growth of the isospin fluctuation only. The magnitude of both fluctuations decreases with the increasing isospin asymmetry because of the larger reduction of the attractive isoscalar mean field by the stronger repuslive neutron symmetry potential in the more neutron-rich matter. Moreover, it is shown that the isospin fractionation happens later, but grows faster in the more neutron-rich matter. Implications of these results to current experiments exploring properties of neutron-rich matter are discussed.Comment: 18 pages & 15 figures, Nuclear Physics A (2001) in pres

Incorporating metapopulation Dynamics to Inform Invasive Species Management: Evaluating Bighead and Silver Carp Control Strategies in the Illinois River

1. Invasive species management can benefit from predictive models that incorporate spatially explicit demographics and dispersal to guide resource allocation decisions. 2. We used invasive bigheaded carps (Hypophthalmichthys spp.) in the Illinois River, USA as a case study to create a spatially explicit model to evaluate the allocation of future management efforts. Specifically, we compared additional harvest (e.g. near the invasion front vs. source populations) and enhanced movement deterrents to meet the management goal of reducing abundance at the invasion front. 3. We found additional harvest in lower river pools (i.e. targeting source populations) more effectively limited population sizes upriver at the invasion front compared to allocating the same harvest levels near the invasion front. Likewise, decreasing passage (i.e. lock and dam structures) at the farthest, feasible downriver location limited invasion front population size more than placing movement deterrents farther upriver. 4. Synthesis and applications. Our work highlights the benefits of adopting a multipronged approach for invasive species management, combining suppression of source populations with disrupting movement between source and sink populations thereby producing compounding benefits for control. Our results also demonstrate the importance of considering metapopulation dynamics for invasive species control programs when achieving long-term management goals

The New Hard X-ray Mission

The Italian New Hard X-ray Mission (NHXM) has been designed to provide a real breakthrough on a number of hot astrophysical issues that includes: black holes census, the physics of accretion, the particle acceleration mechanisms, the effects of radiative transfer in highly magnetized plasmas and strong gravitational fields. NHXM is an evolution of the HEXIT-Sat concept and it combines fine imaging capability up to 80 keV, today available only at E<10 keV, with sensitive photoelectric imaging polarimetry. It consists of four identical mirrors, with a 10 m focal length, achieved after launch by means of a deployable structure. Three of the four telescopes will have at their focus identical spectral-imaging cameras, while X-ray imaging polarimetric cameras will be placed at the focus of the fourth. In order to ensure a low and stable background, NHXM will be placed in a low Earth equatorial orbit. In this paper we provide an overall description of this mission that is currently in phase B.Comment: 9 pages, 5 figures. Accepted for publication on PoS, proceedings of "The Extreme sky: Sampling the Universe above 10 keV", held in Otranto (Italy), 13-17 October 200

Conference of Microelectronics Research 2002

https://scholarworks.rit.edu/meec_archive/1011/thumbnail.jp

Monitoring within non-native ungulate exclosures documents the inherent size of Crocanthemum greenei (Cistaceae)

Crocanthemum greenei (B.L.Rob.) Sorrie (Cistaceae), a perennial sub-shrub, was measured as part of a demographic monitoring effort on Santa Catalina Island, California, USA (hereafter, Catalina). Introduced ungulate browsers remain present on Catalina. Consequently, many palatable plant taxa on the island are subject to and putatively limited by top-down browsing forces. Historically, introduced ungulates have also been present on each island throughout the range of C. greenei. Habitat conservation work, resulting in the construction of ungulate exclosures on Catalina, has now allowed us to measure individuals in their mature, non-browsed form. The published value for C. greenei stem (height) is usually 15–30 cm. While the original description hints at a greater potential size, recent descriptions appear to be influenced by observations made during the decades when plants would have been impacted by introduced ungulate herbivores. Here we present stem measurements of 81 adult individuals, with a median of 49 cm and an interquartile range of 42–56 cm. These measurements suggest an expanded stem (height) range of 15–60 cm better describes the taxon and shed light on the historical impacts of invasive ungulates across the islands and those continuing on Catalina

A multi-centre, single-arm, open-label study evaluating the safety and efficacy of fixed dose rituximab in patients with refractory, relapsed or chronic idiopathic thrombocytopenic purpura (R-ITP1000 study)

The efficacy of a fixed-dose rituximab schedule was prospectively explored in primary/acute refractory, relapsed or chronic (platelet count >10 × 109/l and ≤50 × 109/l) idiopathic thrombocytopenic purpura (ITP). Patients received two doses of rituximab (1000 mg) on days 1 and 15 and were followed-up on weeks 1-8, 12, 26, 39 and 52. A total of 122 patients were included in the safety population; efficacy was analysed in 108 patients. Overall response rate (ORR) at week 8, defined as the proportion of patients achieving complete response (CR; platelet count >150 × 109/l) or partial response (PR; platelet count >50 × 109/l) was 44%. Therapeutic response, defined as achieving a response at week 8, with at least a minor response (MR; platelet count >30 × 109/l), sustained up to weeks 26 and 52 and accompanied by a reduction in ITP medications, was achieved in 44% (week 26) and 35% (week 52) of patients, respectively. Treatment was well tolerated with no safety concerns. While this study failed to meet its primary endpoint of an ORR of 50%, the efficacy of two fixed doses of rituximab appear to provide similar efficacy to the standard 375 mg/m2 four-dose schedule in relapsed/chronic ITP

The inner workings of the outer surface: skin and gill microbiota as indicators of changing gut health in Yellowtail Kingfish

&copy; 2018 Legrand, Catalano, Wos-Oxley, Stephens, Landos, Bansemer, Stone, Qin and Oxley. The mucosal surfaces and associated microbiota of fish are an important primary barrier and provide the first line of defense against potential pathogens. An understanding of the skin and gill microbial assemblages and the factors which drive their composition may provide useful insights into the broad dynamics of fish host-microbial relationships, and may reveal underlying changes in health status. This is particularly pertinent to cultivated systems whereby various stressors may led to conditions (like enteritis) which impinge on productivity. As an economically important species, we assessed whether the outer-surface bacterial communities reflect a change in gut health status of cultivated Yellowtail Kingfish (Seriola lalandi). Active bacterial assemblages were surveyed from RNA extracts from swabs of the skin and gills by constructing Illumina 16S rRNA gene amplicon libraries. Proteobacteria and Bacteroidetes were predominant in both the skin and gills, with enrichment of key &szlig;-proteobacteria in the gills (Nitrosomonadales and Ferrovales). Fish exhibiting early stage chronic lymphocytic enteritis comprised markedly different global bacterial assemblages compared to those deemed healthy and exhibiting late stages of the disease. This corresponded to an overall loss of diversity and enrichment of Proteobacteria and Actinobacteria, particularly in the gills. In contrast, bacterial assemblages of fish with late stage enteritis were generally similar to those of healthy individuals, though with some distinct taxa. In conclusion, gut health status is an important factor which defines the skin and gill bacterial assemblages of fish and likely reflects changes in immune states and barrier systems during the early onset of conditions like enteritis. This study represents the first to investigate the microbiota of the outer mucosal surfaces of fish in response to underlying chronic gut enteritis, revealing potential biomarkers for assessing fish health in commercial aquaculture systems

The Inner Workings of the Outer Surface: Skin and Gill Microbiota as Indicators of Changing Gut Health in Yellowtail Kingfish

The mucosal surfaces and associated microbiota of fish are an important primary barrier and provide the first line of defense against potential pathogens. An understanding of the skin and gill microbial assemblages and the factors which drive their composition may provide useful insights into the broad dynamics of fish host–microbial relationships, and may reveal underlying changes in health status. This is particularly pertinent to cultivated systems whereby various stressors may led to conditions (like enteritis) which impinge on productivity. As an economically important species, we assessed whether the outer-surface bacterial communities reflect a change in gut health status of cultivated Yellowtail Kingfish (Seriola lalandi). Active bacterial assemblages were surveyed from RNA extracts from swabs of the skin and gills by constructing Illumina 16S rRNA gene amplicon libraries. Proteobacteria and Bacteroidetes were predominant in both the skin and gills, with enrichment of key β-proteobacteria in the gills (Nitrosomonadales and Ferrovales). Fish exhibiting early stage chronic lymphocytic enteritis comprised markedly different global bacterial assemblages compared to those deemed healthy and exhibiting late stages of the disease. This corresponded to an overall loss of diversity and enrichment of Proteobacteria and Actinobacteria, particularly in the gills. In contrast, bacterial assemblages of fish with late stage enteritis were generally similar to those of healthy individuals, though with some distinct taxa. In conclusion, gut health status is an important factor which defines the skin and gill bacterial assemblages of fish and likely reflects changes in immune states and barrier systems during the early onset of conditions like enteritis. This study represents the first to investigate the microbiota of the outer mucosal surfaces of fish in response to underlying chronic gut enteritis, revealing potential biomarkers for assessing fish health in commercial aquaculture systems