512 research outputs found

    Primary pleural myxoid liposarcoma: case report and literature review

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    Myxoid liposarcoma is a histological subtype of malignant tumors within the group of sarcomas. It is more common in men between the ages of 40 and 50 years. Diagnosis is difficult because they are usually asymptomatic lesions, computed tomography (CT) scan and magnetic resonance are the studies of choice. The gold of treatment is surgical resection with free margins. Chemotherapy and radiotherapy have shown a good response. A 46-year-old male was detected incidental mediastinal lesion by radiography, CT scan showed a hypodense lesion in the right hemithorax that extended to the left hemithorax, infiltrating the diaphragm and large vessels. The patient underwent an exploratory thoracotomy, finding a multilobulated tumor and mucous content approximately 600 ml, adjacent structures were infiltrated, so complete resection was not possible. Subsequently, adjuvant chemotherapy given. The histopathological diagnosis was myxoid liposarcoma. Myxoid liposarcoma is a malignant lesion. The primary pleural origin is rare. Surgical resection with free margins has a good prognosis. Due to advanced disease, a complete resection in this case was not possible, that compromised the patient prognosis

    Pulmonary artery mycotic aneurism owing to aspergillus in SARS-CoV-2 convalescent: a case report and literature review

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    Invasive aspergillosis is a severe illness described in immune-compromised and critically ill non-immuno-compromised patients. Aspergillosis and COVID-19 co-infection cases harbor multiple unfavorable prognostic factors, with a 44% mortality versus 19% without aspergillosis. We presented the case of a 61-year-old man known with hypertension, diabetes, and smoking that went through COVID-19 infection, during the convalescent period presented multiple hemoptoic events due to A. fumigatus mycotic pseudoaneurysm, successfully resolved by selective angioembolization. Selective angioembolization is an effective alternative for high surgical risk due to comorbidities in the treatment of pulmonary mycotic aneurism

    El sistema histórico de riego de la Vega de Granada. Reconocimiento y protección desde la perspectiva del Patrimonio Agrario

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    [EN] Traditional irrigation systems preserve important natural and cultural values, which deserve protection and reconnaissance. In order to develop this heritage assessment the focus should be placed on the concept of Agrarian Heritage, because despite the important hydraulic values of these systems, irrigation is a mere instrument for agrarian production and human settlements. This paper, based on the Project PAGO (Agrarian Heritage: cultural landscape construction through agrarian activity, HAR2010- 15809), stablishes which are the values that should be considered in the historical irrigation systems, and mainly, the mechanisms and criteria for delimitation and protection, focusing in the study case of the Vega the Granada hydraulic system.[ES] Los sistemas históricos o tradicionales de riego constituyen un tipo de espacio agrario de grandes valores culturales y naturales, los cuales requieren un adecuado reconocimiento y protección. Para proceder a esta valoración patrimonial consideremos que el enfoque adecuado debe ser el derivado del concepto de Patrimonio Agrario, ya que, con independencia de los valores propiamente hidráulicos que disponen estos sistemas, su razón de ser es la irrigación de un territorio para su explotación agraria y, a partir de ahí, la construcción de un asentamiento humano. Tomando como referencia los presupuestos que caracterizan el Patrimonio Agrario, elaborados en el contexto del Proyecto PAGO (El Patrimonio Agrario. La construcción cultural del territorio a través de la actividad agraria, HAR2010-15809), en este texto establecemos cuáles son los valores que deben reconocerse en los sistemas históricos de riego y, sobre todo, los criterios y mecanismos a utilizar para su delimitación y protección. Para avalar todas estas propuestas utilizamos como ejemplo el caso de la Vega de Granada, cuyo extraordinario sistema hidráulico está siendo objeto de un estudio en profundidad por parte del Proyecto PAGO.Castillo Ruiz, J.; Martínez Hidalgo, C.; Pérez Córdoba, G. (2015). El sistema histórico de riego de la Vega de Granada. Reconocimiento y protección desde la perspectiva del Patrimonio Agrario. En Irrigation, Society and Landscape. Tribute to Tom F. Glick. Editorial Universitat Politècnica de València. 763-790. https://doi.org/10.4995/ISL2014.2014.190OCS76379

    Finding Respondents from Minority Groups

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    The recruitment of respondents belonging to ethnic minorities poses important challenges in social and health research. This paper reflects on the enablers and barriers to recruitment that we encountered in our research work with persons belonging to ethnic minorities. Additionally, we applied the Matching Model of Recruitment, a theoretical framework concerning minority recruitment, to guide our reflection. We also explored its applicability as a research design tool. In assessing our research experience, we learned that minority recruitment in social and health research is influenced by the social context of all key players involved in the research. Also, there are enablers and barriers within that social context facilitating or delaying the recruitment process. The main enablers to recruit respondents belonging to ethnic minorities include working with community agencies and gatekeepers who share a common vision with researchers and the latter’s ability to gain the trust of potential respondents. The main barriers include demanding too much from these same community agencies and gatekeepers and ignoring factors that could delay the completion of the research. Although we found the Matching Model of Recruitment to be an effective tool in assessing the processes of recruiting respondents belonging to ethnic minorities, further empirical research is needed to explore its usefulness during the research planning phase

    The importance of atmospheric correction for airborne hyperspectral remote sensing of shallow waters: application to depth estimation

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    Accurate determination of water depth is indispensable in multiple aspects of civil engineering (dock construction, dikes, submarines outfalls, trench control, etc.). To determine the type of atmospheric correction most appropriate for the depth estimation, different accuracies are required. Accuracy in bathymetric information is highly dependent on the atmospheric correction made to the imagery. The reduction of effects such as glint and cross-track illumination in homogeneous shallow-water areas improves the results of the depth estimations. The aim of this work is to assess the best atmospheric correction method for the estimation of depth in shallow waters, considering that reflectance values cannot be greater than 1.5% because otherwise the background would not be seen. This paper addresses the use of hyperspectral imagery to quantitative bathymetric mapping and explores one of the most common problems when attempting to extract depth information in conditions of variable water types and bottom reflectances. The current work assesses the accuracy of some classical bathymetric algorithms (Polcyn? Lyzenga, Philpot, Benny?Dawson, Hamilton, principal component analysis) when four different atmospheric correction methods are applied and water depth is derived. No atmospheric correction is valid for all type of coastal waters, but in heterogeneous shallow water the model of atmospheric correction 6S offers good results

    El Caso Gabriel y la PPR en la prensa: continuidades y contradicciones entre discursos mediáticos sobre delincuencia y sobre política penal

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    Existe una estrecha vinculación entre el tratamiento mediático de los delitos (sobre todo los más horrendos o espectaculares), la percepción social de la delincuencia, y la evolución de la política penal de una sociedad dada. Un aspecto hasta ahora escasamente estudiado de ese tema son las maneras en que los discursos mediáticos sobre delincuencia interactúan con los discursos mediáticos sobre política penal. Este capítulo expone los presupuestos teórico-metodológicos y primeros resultados de una propuesta de investigación que aborda este problema teórico desde el análisis de un caso de estudio concreto: la comparación entre los discursos con que una serie de periódicos (El País, El Mundo, Público y OK Diario) trataron, durante los mismos días, el asesinato conocido como Caso Gabriel y el debate público en torno a la Prisión Permanente Revisable (PPR). La hipótesis de partida es que, en dicho debate, cada periódico mantuvo un discurso coherente con su adscripción ideológica (algunos a favor, y otros en contra, de la PPR), mientras que al hablar del Caso Gabriel, todos los medios manejaron discursos muy parecidos, mucho más coherentes con una posición política pro-PPR que con su opuesta. De ser así, esto colocaría a los periódicos anti-PPR en una posición de enorme debilidad discursiva, casi de incapacidad para intervenir con solvencia en ese debate, frente a la solidez y fortaleza lógicas y retóricas de los periódicos pro-PPR

    Adipose-derived stem cells and platelet-rich plasma for preventive treatment of bisphosphonate-related osteonecrosis of the jaw in a murine model

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    This is the author’s version of a work that was accepted for publication in Journal of Cranio-Maxillofacial Surgery. A definitive version was subsequently published in Journal of Cranio-Maxillofacial Surgery 43.7 (2015) DOI: 10.1016/j.jcms.2015.04.026Objectives: The main challenge in treating bisphosphonate-related osteonecrosis of the jaw (BRONJ) is the absence of an effective established treatment. We aimed to compare different potentially preventive treatments for BRONJ after dental extractions in zoledronic acid (ZA)-treated animals. We studied the local application of different combinations of adipose-derived stem cells (ASCs) with or without previous stimulation with bone morphogenetic protein 2 (BMP-2) and platelet-rich plasma (PRP) in rats. Material and methods: Fifty-six male Wistar rats were treated with ZA for 9 weeks. Dental extractions were performed in the eighth week, and the animals were divided into 4 groups. In group 1 (n ¼ 14), alveolar coverage with mucoperiosteal flap was performed. In group 2 (n ¼ 14), PRP was applied over the sockets and covered with the flap. In group 3 (n ¼ 15), allogeneic ASCs with PRP were applied and covered with the flap. In group 4 (n ¼ 13), animals were treated with ASCs cultured with BMP-2, PRP, and flap coverage. Histologic, fluorescence, and radiologic studies of the maxillae were performed. Results: ASC-treated animals showed lower frequency of osteonecrosis (14% vs 50%, p ¼ 0.007) and greater bone turnover (p ¼ 0.024) and osteoclast count (p ¼ 0.045) than those not receiving the ASC treatment. Conclusions: In this high-risk model, ASC-based treatments seem to prevent BRONJ more effectively than mucosal flap with or without PRP. The combination of ASCs and PRP appears to be synergistic, and the addition of BMP-2 could further improve the resultsThis study was supported by a grant from the Spanish Ministry of Health and Consumer Affairs (FIS PI10/01991) and a RETICS grant from ISCIII (RD12/0019/0035) and the Education Council of Madrid (P2010/BMD-2420)

    Cross-sectional study of height and weight in the population of Andalusia from age 3 to adulthood

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    <p>Abstract</p> <p>Background and objectives</p> <p>In Andalusia there were no studies including a representative sample of children and adolescent population assessing growth and weight increase. Our objectives were to develop reference standards for weight, height and BMI for the Andalusian pediatric population, from 3 to 18 years of age for both genders, and to identify the final adult height in Andalusia.</p> <p>Subjects and methods</p> <p>Two samples were collected. The first included individuals from 3 to 18 years of age (3592 girls and 3605 boys). They were stratified according type of study center, size of population of origin, age (32 categories of 0.5 years) and gender, using cluster sampling. Subjects from >18 to 23 years of age (947 women and 921 men) were sampled in 6 non-university educational centers and several university centers in Granada. Exclusion criteria included sons of non-Spanish mother or father, and individuals with chronic conditions and/or therapies affecting growth. Two trained fellows collected the data through February to December 2004, for the first sample, and through January to May 2005, for the second.</p> <p>Reference curves were adjusted using Cole's LMS method, and the quality of the adjustment was assessed using the tests proposed by Royston. In addition, a sensitivity analysis was applied to the final models obtained.</p> <p>Results</p> <p>Data for 9065 cases (4539 women and 4526 men) were obtained; 79.39% (n = 7197) in the up to 18 years of age group. In the first sampling only 0.07% (3 girls and 2 boys) refused to participate in the study. In addition, 327 students (4.5%) were absent when sampling was done. We present mean and standard deviation fort height, weight and BMI at 0.5 years intervals, from 3 to 23 years of age, for both genders. After adjustment with the different models, percentiles for height, weight (percentiles 3, 5, 10, 25, 50, 75, 90, 95, and 97) and BMI (percentiles 3, 5, 50, 85, 95, and 97) are presented for both genders.</p> <p>Conclusion</p> <p>This is the first study in Andalusia with a representative sample from the child-juvenile population to investigate weight, height and BMI in subjects from 3 to 23 years of age. The great variability observed in the values from sample of 18 to 23 years of age individuals, ensures the inclusion of extreme values, although random sampling was not used. There still is a lack of standard reference values for the Andalusian population younger done 3 years of age.</p

    Evolution of oral neoplasm in an andalusian population (Spain)

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    Head and neck cancer are one of the most common neoplasm pathologies in humans. The aim of this study was to analyze the type, characteristics, treatment and evolution of oral neoplasm or precancerous lesion in a sample of Andalusian population (Spain) derived from the Oncology Rehabilitation Hospital Unit during a period of 20 years. A retrospective descriptive study was carried out during the years 1991 and 2011 analyzing the type, characteristics, treatment and follow-up of oral neoplasm in the Oral and Maxillofacial Surgery Unit of the Universitary Hospital ?Virgen del Rocío?. The inclusion criteria were patients whose underlying pathology was any type of benign or malignant neoplasm or presence of precancerous lesion that, after treatment, had been referred to the Prosthetic Rehabilitation Unit. Of the initial analyzed sample of 60 patients, only 45 patients met the inclusion criteria. Of the final sample analyzed, 31 subjects were men (68.9%) and 14 women (31.1%) (p = 0.0169). The mean age of the sample was 57 years ± 13.83, been more frequently in older people with more than 50 years (73.3%) (p = 0.0169). The most common type of neoplasm was epidermoid carcinoma (64.4%). The site most frequently found in squamous cell carcinoma was the floor of the mouth (31%). The most frequent treatment modality was surgery with postoperative radiotherapy (42.2%). All patients had a minimum follow-up of 5 years, and a recurrence in this period was identified in 11.1% of the sample. Multivariate logistic regression showed a statistically significant association for the variables age (p = 0.0063) and smoking (p = 0.0434). Epidermoid carcinoma is the most frequent tumor in the oral cavity, where increase age and smoking are confirmed as associated risk factors
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