124 research outputs found
One person with two DNA profiles: a(nother) case of mosaicism or chimerism
Nuclear DNA markers, such as short tandem repeats (STR), are widely used for crime investigation and paternity testing. STR were used to determine whether a piece of tissue regurgitated by a dog was part of the penis of a dead, emasculated, man. Unexpectedly, when analyzing the recovered material and a blood sample from the deceased, five out of the 18 loci differed. According to the results, one could have concluded that these samples originated from two different persons. However, taking into account contextual information and data from complementary genetic analyses, the most likely hypothesis was that the deceased was a genetic mosaic or a chimera. Within a forensic genetic context, such genetic peculiarities may prevent associating the perpetrator of an offense with a stain left at a crime scene or lead to false paternity exclusions. Fast recognition of mosaics or chimeras, adapted sampling scheme, as well as careful interpretation of the data should allow avoiding such pitfall
Model Rocket Workshop
This project was done in order to determine whether the theoretical analysis of the trajectory of the
launching of a model rocket and its actual experimental trajectory match. To do so, a rocket model was
built and launched, its trajectory being recorded by an altimeter. The theoretical and experimental results
did not correspond, allowing us to argue why this could have happened.2015/201
Introducció a la domòtica i estalvi energètic
Treball final de màster per facilitar la introducció de la domòtica a l’educació secundària
obligatòria a través de la resolució de reptes per l’alumnat. Els reptes es plantegen per
solucionar una problemàtica de l’entorn de l’habitatge.
Per arribar a la solució els alumnes han de plantejar la solució, elaborar el disseny i han de
realitzar la solució final.
Durant tot el procés es van introduint conceptes de domòtica a través de la utilització de la
placa Arduino UNO. Es comença a segon d’ESO amb la introducció del sensor de
temperatura per la monitorització d’aquesta amb el programari S4A (Scratch for Arduino).
En el segon cicle, tercer i quart d’ESO, l’alumne aprèn a programar amb l’aplicació
Processing a través de la utilització de la llibreria d’Arduino per facilitar la comunicació
entre el PC i la placa. S’utilitzen les sentencies de programació bàsiques per realitzar
accions i controlar el sistema domòtic.
Les pràctiques que es realitzen són transversals, es a dir, es poden aprofitar d’un curs a
un altres. Així els alumnes de 4rt curs poden aprofitar el disseny que s’ha elaborat a 3er
d’ESO.
El resultat és un conjunt de practiques preparades per ser aplicades a la secundària. Amb
les solucions i el desenvolupament del codi necessari per la programació
A escolha dos patrocinadores no desporto : o estudo de caso da Sagres
Mestrado em Gestão do Desporto - Organizações DesportivasEste estudo tem como objetivo a escolha dos patrocinadores no desporto da marca Sagres. Para o efeito abordou-se os objetivos do patrocínio, o processo de seleção na escolha dos patrocínios e o processo de avaliação da eficácia das entidades patrocinadas. A abordagem metodológica foi o estudo de caso e utilizou-se a entrevista na recolha de dados e a análise de conteúdo no seu tratamento.
Através dos resultados obtidos, foi possível compreender que dentro dos objetivos corporativos e de estratégia de marketing, o fator agregação, serve como elemento principal na escolha do patrocínio no desporto para a Sagres. A ligação ao Futebol é a principal aposta da marca ao nível de interesse pessoal da gestão, e dentro do campo dos media, a Televisão é também a primeira escolha. Relativamente ao processo de selecão de patrocínios, deve-se realçar o facto de que instituições com maiores fatores agregadores servem como principal escolha, tal como entidades desportivas mais expressivas com identificação do target de consumidores da marca. Em relação ao processo de avaliação da eficácia das entidades patrocinadas, o retorno obtido é o principal fator de avaliação.
Pela análise dos resultados da entrevista efetuada, concluímos que a Sagres abrange todos os setores da sociedade e tem incorporado no seu ADN a portugalidade, ou seja, a coesão do povo português em todo o mundo. A marca está intimamente ligada ao Futebol, porque entende que em termos de comunicação, existem fatores em comum com a cerveja Sagres
Validació d'un model de simulació d'un sistema automàtic de conducció
Validació d'un model teòric d'un sistema automàtic de conducció mitjançant dades de les simulacions efectuades amb l'eina dissenyada
Fanconi anemia protein FANCD2 inhibits TRF1 polyADP-ribosylation through tankyrase1-dependent manner
Background: Fanconi anemia (FA) is a rare autosomal recessive syndrome characterized by developmental abnormalities, progressive bone marrow failure, and predisposition to cancer. The key FA protein FANCD2 crosstalks with members of DNA damage and repair pathways that also play a role at telomeres. Therefore, we investigated whether FANCD2 has a similar involvement at telomeres. Results: We reveal that FANCD2 may perform a novel function separate to the FANCD2/BRCA pathway. This function includes FANCD2 interaction with one of the telomere components, the PARP family member tankyrase-1. Moreover, FANCD2 inhibits tankyrase-1 activity in vitro. In turn, FANCD2 deficiency increases the polyADP-ribosylation of telomere binding factor TRF1. Conclusions: FANCD2 binding and inhibiting tankyrase-1PARsylation at telomeres may provide an additional step within the FA pathway for the regulation of genomic integrity
Effetti del formulato “Califol” a base di ossido di calcio sulla peronospora del basilico allevato in vaso
Study on the Union’s situation and options regarding invertebrate biological control agents for the use in plant health and plant protection
Post-partum surgical wound infections: incidence after caesarean section in an Italian hospital
Introduction. Despite international recommendations and gen- eral agreement on the fact that more complications arise after caesarean section, Italy ranks first in the number of caesarean sections performed each year. Aim of this cohort study was to estimate the incidence of post-partum wound infections following caesarean section in a sample of low-risk women and to examine the main risk factors correlated. Methods. 430 mothers were included in the study. A data col- lection form was completed with woman?s obstetric history, details of the operation and of any infection that occurred during hospital staying. A post-discharge telephone call-up surveillance after delivery was also performed Results. A total of 20 (4.7%) SSIs were recorded. Through post-discharge surveillance, 85% of infections were identified. The time between membrane rupture and start of the operation was found to be associated with the development of infection (p = 0.04). No statistically significant association with any of the other risk factors was found. Discussion and conclusion. From the comparison of current practices with international guideline recommendations we could identify critical points that will need to be addressed in correc- tive and training interactions, specifically, choice and timing of administration of antibiotics in antimicrobial prophylaxis and timing of showering and shaving
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