Eviterna

[ES] En la presente investigación, de tipología cuatro, se plantea un proyecto audiovisual experimental. El video mezclado con la fotografía, logra romper determinados límites establecidos en el campo visual, rompiendo los límites entre imagen fija e imagen en movimiento. Se trata de un proceso creativo, en el que se producen fotografías que posteriormente serán manipuladas manualmente y donde se graba dicha manipulación en video, gracias a la utilización de elementos naturales como el agua, el fuego y la tierra. Junto a ello, se explora el concepto del tiempo de la imagen culminando en la experimentación plástica de la obra. A lo largo de este proyecto, se indaga en el concepto del cuerpo en relación con la naturaleza, la poética del video y la fotografía como proceso experimental en sí, utilizando el cuerpo de la artista en primer plano, desde un criterio experimental y autobiográfico, fotografiando el cuerpo sin filtros y donde se trabajan posteriormente las imágenes hasta convertirlas en video. Este proceso nos dará pie a la investigación plástica desarrollada para la cual se ha investigado utilizando fuentes bibliográficas y referenciales artísticas que afianzan las bases del trabajo.[EN] In the present research, of typology four, an experimental audiovisual project is proposed. The video mixed with photography, manages to break certain limits established in the visual field, breaking the boundaries between fixed image and moving image. It is a creative process, in which photographs that are captured will be later manipulated manually and where this manipulation is recorded on video, thanks to the use of natural elements such as water, fire and ground. Along with this, the concept of time in the image is explored, culminating the plastic arts experimentation of the work. Throughout this project, the concept of the body is explored in relation to nature, the poetics of video and photography as an experimental process in itself, using the artist's body in the foreground, from an experimental and autobiographical criteria, photographing the body without filters and where the images are subsequently worked on until they are converted into video. This process will lead us to the plastic arts research developed for which has been investigated using bibliographical sources and artistic references that strengthen the basis of the work.Castell Pérez, S. (2023). Eviterna. Universitat Politècnica de València. http://hdl.handle.net/10251/19980

ECOSENSORIA: Explorando la Regeneración Ambiental a través de la Experiencia Sensorial en el Cabo de Santa Pola

Se trata de proyectar experimentando con la capacidad de los sentidos para conectar con el entorno y poniendo en valor el poder experiencial en proyectos de espacio público, concretamente en el ámbito del paraje natural del Cabo de Santa Pola. Se parte de la propia experiencia y de la investigación en otros casos de estudio como herramientas para la elaboración de estrategias y la intervención en el ámbito de trabajo. Por tanto, el objetivo principal del proyecto es regenerar el espacio del frente del Cabo, creando espacios naturales en los que se desarrollan múltiples actividades que ponen en valor la experiencia sensorial, reconfigurando las zonas degradadas y diseñando itinerarios relacionando el mar y el Cabo

Les Femmes

[ES] "El día que una mujer pueda no amar con su debilidad sino con su fuerza, no escapar de sí misma sino encontrarse, no humillarse sino afirmarse, ese día el amor será para ella, como para el hombre, fuente de vida y no un peligro mortal." Con esta cita de Simone de Beauvoir se da pie al trabajo fotográfico, con la intención de hacer pedazos el silencio de las víctimas que han sufrido violencia de género y visibilizar la desigualdad que nuestra sociedad aún sufre en pleno siglo XXI. Parte de este trabajo, está inspirado en los Cuadernos de Quejas, para ello se ha creado un fotolibro con todas las fotografías tomadas a lo largo del proyecto y los testimonios recopilados durante su elaboración, profundizando en sus sentimientos y emociones.[EN] "On the day when it will be possible for woman to love not in her weakness but in strength, not to escape herself but to find herself, not to abase herself but to assert herself, on that day love will become for her, as for the man, a source of life and not of mortal danger." This quote from Simone de Beauvoir gives rise to the photographic work, with the intention to shatter the silence of the victims who have suffered gender violence and to give visibility to the inequality that our society still suffers in the 21st century. Part of this work is inspired by the Notebooks of Complaints. To this end, a photobook has been created by including all the photographs taken throughout the project and the testimonies collected during it¿s elaboration, deepening in the victims¿ feelings and emotions.Castell Pérez, S. (2021). Les Femmes. Universitat Politècnica de València. http://hdl.handle.net/10251/169572TFG

Effect of cocoa-enriched diets on lymphocytes involved in adjuvant arthritis in rats

Cocoa and its flavonoids have potential anti-inflammatory properties in vitro and in acute inflammation models in vivo. The aim of the present study was to ascertain the effects of two cocoa-enriched diets on adjuvant arthritis (AA) in rats, considering not only clinical and biochemical inflammatory indices, but also antibody response and lymphocyte composition. Female Wistar rats were fed with a 5 or 10 % cocoa-enriched diet beginning 2 weeks before arthritis induction and until the end of the study. AA was induced by an intradermal injection of heat-killed Mycobacterium butyricum suspension. The hind-paw swelling (plethysmometry), serum anti-mycobacterial antibody concentration (ELISA), blood and inguinal lymph node lymphocyte subset percentage (flow cytometry), and IL-2, interferon γ and PGE2 released from splenocytes (ELISA) were assessed. Although the cocoa diets had no significant effect on hind-paw swelling, a tendency to reduce it was observed at the end of the study. Cocoa-enriched diets were able to decrease the serum anti-mycobacterial antibody concentration and the splenocyte PGE2 production, as well as the proportion of T-helper (Th) lymphocytes in blood and regional lymph nodes, which probably includes cells responsible for the arthritic process. The cocoa diets prevented a decrease in the proportion of regulatory T-cells in blood and a disequilibrium between inguinal lymph node natural killer (NK) CD8+ and NK CD8− subsets. In conclusion, the cocoa-enriched diets during AA were not able to significantly decrease joint inflammation but modified Th-cell proportions and prevented specific antibody synthesis

Effects of a cocoa diet on an intestinal inflammation model in rats

Cocoa is a rich source of fiber and flavonoids with recognized antioxidant and anti-inflammatory potential. The aim of this study was to evaluate the effects of a cocoa-enriched diet on rats with dextran sulphate sodium (DSS)-induced colitis. Wistar rats were fed with either a 5% cocoa diet or standard diet. Colon inflammation was induced by DSS in the drinking water: 5% for 6 days and 2% over the following 9 days. Colitis was assessed by body weight loss, stool consistency and blood presence in stools. A group of animals fed standard diet was treated with quercitrin (1 mg/kg) after colitis establishment. After 2 weeks of DSS treatment, the colon oxidative and inflammatory status and lymphocyte composition from blood and mesenteric lymph nodes (MLN) were assessed. The cocoa-fed group did not exhibit amelioration of clinical colitis but displayed higher antioxidant activity than the colitic reference group by the restoration of colon glutathione content and prevention of lipid peroxidation. The cocoa diet showed anti-inflammatory potential because it down-regulated serum TNF-alpha, colon iNOS activity and decreased colon cell infiltration. Lymphocyte composition in MLN was not modified by drinking DSS, but there was an increase in the proportion of NK and regulatory T cells in the blood. These changes were not modified by cocoa. In conclusion, cocoa intake may help to inhibit the negative oxidative effects consequent to colitis, although this action is not enough to abrogate the intestinal inflammation significantly

Distribution of epicatechin metabolites in lymphoid tissues and testes of young rats with a cocoa-enriched diet

An increasing number of scientific studies support that flavanol-rich foods and beverages such as cocoa can promote human health, and are beneficial agents for the prevention of some diseases. Our previous studies showed that long-term cocoa intake enhances the antioxidant status in lymphoid organs and also modulates lymphocyte functionality in healthy young rats. Cocoa polyphenolic antioxidants seem to be the best candidates for those effects. However, data regarding polyphenol metabolites in tissues after a long-term cocoa intake are scarce. In the present study we mainly focus on the uptake and accumulation of epicatechin metabolites in lymphoid organs, including the thymus, spleen and mesenteric lymphoid nodes, as well as in the liver and testes after a diet rich in cocoa. Ten young weaned Wistar rats were fed randomly with a 10 % (w/w) cocoa diet or a control diet for 3 weeks, corresponding to their infancy and youth. Tissues were treated with a solid-phase extraction and analysed by liquid chromatography-tandem MS. The major compounds recovered in these tissues were glucuronide derivatives of epicatechin and methylepicatechin. The highest concentration of these metabolites was found in the thymus, testicles and liver, followed by lymphatic nodes and spleen. The high amount of epicatechin metabolites found in the thymus supports our previous findings showing its high antioxidant capacity compared with other tissues such as the spleen. Moreover, this is the first time that epicatechin metabolites have been found in high concentrations in the testes, confirming other studies that have suggested the testes as an important site of oxidation

Respuesta humoral a dos inmunógenos contra la Peste Porcina Clásica en condiciones de campo

La Peste Porcina Clásica (PPC) es una enfermedad altamente contagiosa, presente en Cuba de forma endémica, por lo que está sujeta a un programa de control que incluye la vacunación con la vacuna viva atenuada de la cepa China lapinizada (LABIOFAM, S.A.), de probada seguridad y efectividad. Por las bondades que brinda el uso de una vacuna marcadora en fases avanzadas del control, fue aplicado en condiciones de campo un candidato vacunal de subunidad, basado en la glicoproteína E2 (CVE2) del virus de la peste porcina clásica. Se comparó la respuesta serológica inducida por el nuevo candidato vacunal con la inducida por la vacuna cepa China (VCC) en un mismo escenario epidemiológico, una granja porcina con antecedentes de manifestación clínica de la enfermedad y sujeta a vacunación sistemática con la VCC. Se evaluó la respuesta inmune humoral de animales vacunados con ambos productos mediante el ensayo de neutralización ligado a la peroxidasa (NPLA). Para ello se investigaron muestras de sangre obtenidas en diferentes fases del ciclo tecnológico. Se encontró en los sueros evaluados de animales vacunados con el CVE2 que estos mantuvieron altos títulos (³ 1:100) hasta el final de la ceba, a diferencia de los vacunados con la VCC. También se comprobó que animales vacunados con la VCC tuvieron un riesgo relativo 12,2 veces mayor de tener títulos de anticuerpos <1:50 que los vacunados con el CVE2

The handbook for standardized field and laboratory measurements in terrestrial climate change experiments and observational studies (ClimEx)

Climate change is a world-wide threat to biodiversity and ecosystem structure, functioning and services. To understand the underlying drivers and mechanisms, and to predict the consequences for nature and people, we urgently need better understanding of the direction and magnitude of climate change impacts across the soil-plant-atmosphere continuum. An increasing number of climate change studies are creating new opportunities for meaningful and high-quality generalizations and improved process understanding. However, significant challenges exist related to data availability and/or compatibility across studies, compromising opportunities for data re-use, synthesis and upscaling. Many of these challenges relate to a lack of an established 'best practice' for measuring key impacts and responses. This restrains our current understanding of complex processes and mechanisms in terrestrial ecosystems related to climate change. To overcome these challenges, we collected best-practice methods emerging from major ecological research networks and experiments, as synthesized by 115 experts from across a wide range of scientific disciplines. Our handbook contains guidance on the selection of response variables for different purposes, protocols for standardized measurements of 66 such response variables and advice on data management. Specifically, we recommend a minimum subset of variables that should be collected in all climate change studies to allow data re-use and synthesis, and give guidance on additional variables critical for different types of synthesis and upscaling. The goal of this community effort is to facilitate awareness of the importance and broader application of standardized methods to promote data re-use, availability, compatibility and transparency. We envision improved research practices that will increase returns on investments in individual research projects, facilitate second-order research outputs and create opportunities for collaboration across scientific communities. Ultimately, this should significantly improve the quality and impact of the science, which is required to fulfil society's needs in a changing world.Peer reviewe