Comorbidades psiquiátricas em pacientes com queixas gastrointestinais: relato de caso sobre a importância da medicina centrada na pessoa

Introduction: Psychiatric disorders in patients with gastrointestinal complaints represent a complex clinical challenge, demanding a comprehensive approach to health issues, both mental and physical. Objective: This study aims to analyze the presence of psychiatric comorbidities in patients with gastrointestinal complaints and emphasize the importance of a biopsychosocial model-based approach, both in patient care and medical education. Method: experience report based on the story of a case conducted by eighth-semester Medicine students in a Gastroenterology clinic. Result and Conclusion: A multidisciplinary approach is necessary for patients with gastrointestinal complaints, as these symptoms often coexist with psychiatric symptoms. This underscores the importance of medical education emphasizing person-centered medicine.Introdução: condições psiquiátricas em pacientes com queixas gastrointestinais representam um desafio clínico complexo, exigindo uma abordagem integral das questões de saúde, tanto psíquicas quanto físicas. Objetivo: relatar a presença de comorbidades psiquiátricas em pacientes com queixas gastrointestinais e enfatizar a importância da abordagem baseada no modelo biopsicossocial, tanto na assistência ao paciente quanto na educação médica. Método: relato de experiência construído acerca da história de um caso conduzido por estudantes do oitavo semestre de Medicina em uma clínica de Gastroenterologia. Resultado e conclusão: é necessário a prática de uma abordagem multidisciplinar na medicina, ainda mais para pacientes com queixas gastrointestinais, pois tais sintomas estão presentes diversas vezes com questões psiquiátricas. Isso ressalta a importância da formação médica com a prática da medicina centrada na pessoa.&nbsp

Data Descriptor: An open resource for transdiagnostic research in pediatric mental health and learning disorders

Technological and methodological innovations are equipping researchers with unprecedented capabilities for detecting and characterizing pathologic processes in the developing human brain. As a result, ambitions to achieve clinically useful tools to assist in the diagnosis and management of mental health and learning disorders are gaining momentum. To this end, it is critical to accrue large-scale multimodal datasets that capture a broad range of commonly encountered clinical psychopathology. The Child Mind Institute has launched the Healthy Brain Network (HBN), an ongoing initiative focused on creating and sharing a biobank of data from 10,000 New York area participants (ages 5–21). The HBN Biobank houses data about psychiatric, behavioral, cognitive, and lifestyle phenotypes, as well as multimodal brain imaging (resting and naturalistic viewing fMRI, diffusion MRI, morphometric MRI), electroencephalography, eyetracking, voice and video recordings, genetics and actigraphy. Here, we present the rationale, design and implementation of HBN protocols. We describe the first data release (n =664) and the potential of the biobank to advance related areas (e.g., biophysical modeling, voice analysis

Aportes del modelo de la diversidad a las prácticas de las terapias ocupacionales : análisis desde las perspectivas de terapeutas ocupacionales y usuaries en Argentina durante el año 2021.

Con este trabajo, esperamos poder dar cuenta de la de importancia de la intervención desde un paradigma social. Como es el caso del modelo de la diversidad que no es propio de Terapia Ocupacional y puede brindar aportes valiosos a la profesión, contemplar una mirada más amplia desde una perspectiva de derechos, al momento de intervenir como profesionales de la salud. Los resultados obtenidos en este trabajo final integrador pretenden ser de utilidad principalmente para estudiantes y profesionales de Terapia Ocupacional en Argentina. Esperamos que éstos inviten a repensar el rol profesional que responde a prácticas hegemónicas más relacionadas al modelo médico rehabilitador y se considere adoptar una posición activa como agente de cambio social en pos de los derechos humanos, así como a considerar una perspectiva social de intervención que sea capaz de favorecer el desarrollo de las personas con las que trabajamos. Además, creemos que a profesionales de la salud de otras disciplinas, quienes trabajan inter y transdisciplinariamente con terapeutas ocupacionales, puede resultarles de utilidad nuestro trabajo para incorporar formas de comprensión y prácticas relacionadas con esta perspectiva de derechos humanos en sus intervenciones.Fil: Kopp Castagna, Nicole. Universidad Nacional de San Martín. Instituto de Ciencias de la Rehabilitación y el Movimiento. Buenos Aires, ArgentinaFil: Jablonski, Victoria. Universidad Nacional de San Martín. Instituto de Ciencias de la Rehabilitación y el Movimiento. Buenos Aires, ArgentinaFil: Chaparro, Tamara. Universidad Nacional de San Martín. Instituto de Ciencias de la Rehabilitación y el Movimiento. Buenos Aires, ArgentinaFil: Pérez Benítez, Vanina. Universidad Nacional de San Martín. Instituto de Ciencias de la Rehabilitación y el Movimiento. Buenos Aires, Argentin

From Amorphous to Crystalline Thin-Film FeF₃ Conversion Electrodes by Sputtering Deposition

FeF3 (iron(III) fluoride) is a promising conversion cathode material that possesses a theoretical specific capacity of 712 mAh/g, which is significantly higher than those of commercial layered cathodes, and it paves the way for realizing Co-free, low-cost advanced batteries for portable electronics, transportation, and grids. Here, we report the development of thin-film FeF3 conversion cathodes by the sputtering deposition technique. The chemistry and stoichiometry of the sputtered FeF3 thin films are confirmed by energy-dispersive X-ray spectroscopy and X-ray photoelectron spectroscopy. Through controlling the substrate temperatures (25–600 °C) of the sputtering deposition, amorphous and crystalline FeF3 samples were developed, characterized, and evaluated for electrochemical performance. FeF3 thin-film electrodes exhibit high initial capacity that is close to the theoretical capacity; after 100 cycles, FeF3 electrodes deposited between 100 and 600 °C show stable cycling performance from 31.7 to 59.3% compared to the initial capacity. Moreover, we investigate the relationship between the density, crystallinity, and lithiation potentials of the deposited FeF3 thin-film cathodes and report that the high-density, crystalline FeF3 exhibits a higher lithiation potential (Δ of ∼0.43 V) than the low-density, amorphous FeF3. The development of sputtered thin-film FeF3 presents an opportunity for thin-film battery fabrication and processing

The Healthy Brain Network Biobank: An open resource for transdiagnostic research in pediatric mental health and learning disorders

Innovations in methods and technologies are equipping researchers with unprecedented capabilities for detecting and characterizing pathologic processes in the developing human brain. As a result, there is growing enthusiasm about the prospect of achieving clinically useful tools that can assist in the diagnosis and management of mental health and learning disorders. For these ambitions to be realized, it is critical to accrue large-scale multimodal datasets that capture a broad range of commonly encountered clinical psychopathology. To this end, the Child Mind Institute has launched the Healthy Brain Network (HBN), an ongoing initiative focused on creating and sharing a biobank comprised of data from 10,000 New York City area children and adolescents (ages 5-21). The HBN has adopted a community-referred recruitment model. Specifically, study advertisements seek the participation of families who have concerns about one or more psychiatric symptoms in their child. The HBN Biobank houses data about psychiatric, behavioral, cognitive, and lifestyle (e.g., fitness, diet) phenotypes, as well as multimodal brain imaging, electroencephalography, digital voice and video recordings, genetics, and actigraphy. In this paper, we present the motivation, rationale and design for the HBN along with the initial implementation and evolution of the HBN protocols. We describe the first major open data release (n = 664) containing descriptive, electroencephalography, and multimodal brain imaging data (resting state and naturalistic viewing functional MRI, diffusion MRI and morphometric MRI). Beyond accelerating transdiagnostic research, we discuss the potential of the HBN Biobank to advance related areas, such as biophysical modeling, voice and speech analysis, natural viewing fMRI and EEG, and methods optimization

Lithium Spatial Distribution and Split-Off Electronic Bands at Nanoscale V₂O₅/LiPON Interfaces

A combination of depth-resolved cathodoluminescence spectroscopy (DRCLS) and X-ray photoemission depth profiling (XPS) measured the pronounced changes in both the electronic density of states and lithium composition near the nanoscale LixV2O5/LiPON interface. DRCLS studies of electrochemically lithiated bare V2O5 and the sputter-deposited V2O5 plus LiPON overlayer electrochemically lithiated in stages both showed that in the bulk the luminescence intensity of the “split-off” hybridized bonding density of states was anticorrelated with XPS-measured Li content, decreasing as the Li content increased. However, the LiPON overlayer was found to modify the band structure of the underlying LixV2O5 (LVO) to a depth of at least 30 nm beneath the V2O5 interface. DRCLS spectra near the electrochemically lithiated LiPON/LVO interface showed a significant intensity of the split-off band, implying a low Li content. However, XPS depth profiling revealed a pronounced negative gradient of Li extending from a maximum Li content at the intimate LiPON boundary to its lowest content of ∼30 nm into the V2O5 in the same region, indicating a strong interaction between band structure and Li electrochemical potential near this heterojunction. These results provide evidence for substantial effects on the local band structure near an electrolyte/cathode interface and insights into the electrochemical interface behavior of solid-state batteries in general

Human Immunodeficiency Virus Continuum of Care in 11 European Union Countries at the End of 2016 Overall and by Key Population: Have We Made Progress?

High uptake of antiretroviral treatment (ART) is essential to reduce human immunodeficiency virus (HIV) transmission and related mortality; however, gaps in care exist. We aimed to construct the continuum of HIV care (CoC) in 2016 in 11 European Union (EU) countries, overall and by key population and sex. To estimate progress toward the Joint United Nations Programme on HIV/AIDS (UNAIDS) 90-90-90 target, we compared 2016 to 2013 estimates for the same countries, representing 73% of the population in the region

An open resource for transdiagnostic research in pediatric mental health and learning disorders

AbstractTechnological and methodological innovations are equipping researchers with unprecedented capabilities for detecting and characterizing pathologic processes in the developing human brain. As a result, ambitions to achieve clinically useful tools to assist in the diagnosis and management of mental health and learning disorders are gaining momentum. To this end, it is critical to accrue large-scale multimodal datasets that capture a broad range of commonly encountered clinical psychopathology. The Child Mind Institute has launched the Healthy Brain Network (HBN), an ongoing initiative focused on creating and sharing a biobank of data from 10,000 New York area participants (ages 5–21). The HBN Biobank houses data about psychiatric, behavioral, cognitive, and lifestyle phenotypes, as well as multimodal brain imaging (resting and naturalistic viewing fMRI, diffusion MRI, morphometric MRI), electroencephalography, eye-tracking, voice and video recordings, genetics and actigraphy. Here, we present the rationale, design and implementation of HBN protocols. We describe the first data release (n=664) and the potential of the biobank to advance related areas (e.g., biophysical modeling, voice analysis).</jats:p

Postoperative continuous positive airway pressure to prevent pneumonia, re-intubation, and death after major abdominal surgery (PRISM): a multicentre, open-label, randomised, phase 3 trial

Background: Respiratory complications are an important cause of postoperative morbidity. We aimed to investigate whether continuous positive airway pressure (CPAP) administered immediately after major abdominal surgery could prevent postoperative morbidity. Methods: PRISM was an open-label, randomised, phase 3 trial done at 70 hospitals across six countries. Patients aged 50 years or older who were undergoing elective major open abdominal surgery were randomly assigned (1:1) to receive CPAP within 4 h of the end of surgery or usual postoperative care. Patients were randomly assigned using a computer-generated minimisation algorithm with inbuilt concealment. The primary outcome was a composite of pneumonia, endotracheal re-intubation, or death within 30 days after randomisation, assessed in the intention-to-treat population. Safety was assessed in all patients who received CPAP. The trial is registered with the ISRCTN registry, ISRCTN56012545. Findings: Between Feb 8, 2016, and Nov 11, 2019, 4806 patients were randomly assigned (2405 to the CPAP group and 2401 to the usual care group), of whom 4793 were included in the primary analysis (2396 in the CPAP group and 2397 in the usual care group). 195 (8\ub71%) of 2396 patients in the CPAP group and 197 (8\ub72%) of 2397 patients in the usual care group met the composite primary outcome (adjusted odds ratio 1\ub701 [95% CI 0\ub781-1\ub724]; p=0\ub795). 200 (8\ub79%) of 2241 patients in the CPAP group had adverse events. The most common adverse events were claustrophobia (78 [3\ub75%] of 2241 patients), oronasal dryness (43 [1\ub79%]), excessive air leak (36 [1\ub76%]), vomiting (26 [1\ub72%]), and pain (24 [1\ub71%]). There were two serious adverse events: one patient had significant hearing loss and one patient had obstruction of their venous catheter caused by a CPAP hood, which resulted in transient haemodynamic instability. Interpretation: In this large clinical effectiveness trial, CPAP did not reduce the incidence of pneumonia, endotracheal re-intubation, or death after major abdominal surgery. Although CPAP has an important role in the treatment of respiratory failure after surgery, routine use of prophylactic post-operative CPAP is not recommended