“Aprender a aprender” – una experiencia en geometría analítica

El análisis de las manifestaciones de los alumnos, registradas a través de encuestas y entrevistas, acerca de sus dificultades para asumir con autonomía el propio aprendizaje, nos llevó a iniciar una investigación con el objetivo de elaborar actividades facilitadoras para aprender significativamente, para “aprender a aprender”. Constituimos un equipo, involucrando a otros docentes de las cátedras de Álgebra y Geometría Analítica, orientando nuestras acciones por una parte a la discusión sobre los obstáculos que traban el aprendizaje, atribuibles a dificultades intrínsecas de la disciplina en estudio o a las propias posibilidades del alumnos o a errores pedagógicos y por otra parte a la búsqueda y selección de metodologías válidas para el logro de nuestro objetivo

¿Sobre qué nos enseñan los errores de nuestros alumnos?. 25 años después…

Quienes presentamos el trabajo integramos un proyecto de investigación “Dificultades en el aprendizaje de la matemática básica en carreras de ingeniería” (Faculta de Ciencias Exactas, Ingeniería y Agrimensura, Universidad Nacional de Rosario) que tiene entre sus objetivos diseñar e implementar estrategias didácticas que contribuyan a: Acortar distancias entre niveles educativos, Corregir errores arraigados, Retener a los ingresantes a la Facultad, Comprometer al estudiante en su formación, incentivando su independencia y creatividad, Comprometer a los docentes en el abordaje e implementación de alternativas didácticas más eficaces

Dificultades en el aprendizaje de matemática. Obstáculos y errores en el aprendizaje del concepto de dependencia e independencia lineal

En el marco del proyecto de investigación del que formamos parte: “Dificultades en la enseñanza-aprendizaje de matemática en carreras no matemáticas”, ubicamos este trabajo que presentamos como reporte de investigación, ya que da cuenta del diseño de aquellos ciclos que se corresponden con el análisis a priori de una situación de aprendizaje, la recolección de datos en la propia situación y el análisis a posteriori de los resultados. Nos ocupamos en esta etapa del análisis de los errores puestos de manifiesto por los alumnos de 1º año de las carreras de Ingeniería, en relación a un tema específico del Álgebra Lineal, como es Dependencia e Independencia Lineal

Calcitriol and the Renin Angiotensin System, and Adipose Tissue Inflammation

Adipose tissue is well recognized as an endocrine organ and a source of proinflammatory molecules 1. We recently demonstrated calcitriol stimulates adipocte reactive oxygen species (ROS) production and inflammatory stress (IS), while dietary calcium suppression of calcitriol exerted the opposite effect. These effects are mediated, in part, by calcitriol modulation of intracellular calcium (Ca2+) signaling and mitochondrial potential. However, adipocytes contain a functional RAS, and angiotensin II (ANGII) modulates ROS and IS. Accordingly, we investigated the role of ANGII in mediating calcitriol effects. Calcitriol (1 nM) stimulated NOX4 expression and ROS production in 3T3-L1 adipocytes by 67% (p\u3c0.01), while these effects were reversed by ACE inhibition (enalipril) or antagonism of either ANGII type 1 receptor (AT1R) or ANGII type 2 receptor (AT2R), antagonism. Similarly, ANG (0-.1-1.0 nM) stimulated NOX4 expression (p\u3c0.03) and this effect was reversed by AT1R or AT2R antagonism. Calcitriol and ANGII both suppressed adiponectin expression (p\u3c0.04) and increased IL6 and MCP-1 expression ~2 fold (p\u3c0.03), and these effects were reversed with enalapril or AT2R, but not AT1R, antagonism. These data demonstrate that calcitriol modulation of adipocyte ROS production and IS is modulated, in part, by the adipocyte RAS

The influence of a major sporting event upon emergency department attendances; A retrospective cross-national European study

Major sporting events may influence attendance levels at hospital emergency departments (ED). Previous research has focussed on the impact of single games, or wins/losses for specific teams/countries, limiting wider generalisations. Here we explore the impact of the Euro 2016 football championships on ED attendances across four participating nations (England, France, Northern Ireland, Wales), using a single methodology. Match days were found to have no significant impact upon daily ED attendances levels. Focussing upon hourly attendances, ED attendances across all countries in the four hour pre-match period were statistically significantly lower than would be expected (OR 0.97, 95% CI 0.94–0.99) and further reduced during matches (OR 0.94, 95% CI 0.91–0.97). In the 4 hour post-match period there was no significant increase in attendances (OR 1.01, 95% CI 0.99–1.04). However, these impacts were highly variable between individual matches: for example in the 4 hour period following the final, involving France, the number of ED attendances in France increased significantly (OR 1.27, 95% CI 1.13–1.42). Overall our results indicate relatively small impacts of major sporting events upon ED attendances. The heterogeneity observed makes it difficult for health providers to predict how major sporting events may affect ED attendances but supports the future development of compatible systems in different countries to support cross-border public health surveillance

Copper-Catalyzed Trifluoromethylation of Unactivated Olefins

Activating the inactive: A copper-catalyzed allylic trifluoromethylation of unactivated terminal olefins proceeds under mild conditions to produce linear allylic trifluoromethylated products with high E/Z selectivity (see scheme). The reaction can be applied to a range of substrates bearing numerous functional groups. Furthermore, the reaction is scalable and amenable to a benchtop setup.National Institutes of Health (U.S.) (GM46059)National Institutes of Health (U.S.) (Postdoctoral Fellowship F32GM093532)National Science Foundation (U.S.) (Grant ACHE-9808061)National Science Foundation (U.S.) (Grant DBI-9729592)National Institutes of Health (U.S.) (Grant 1S10RR13886-01

The Influence of Taxation Knowledge, Taxpayer Awareness, and Tax Sanctions on Individual Taxpayer Compliance (At the Bandung Cicadas Primary Tax Office)

This research uses data from KPP Pratama Bandung Cicadas to highlight concerns about taxpayer compliance, especially with regard to self-assessed taxes. When it comes to tax knowledge, awareness, penalties and compliance, researchers have different opinions. The results highlight the influence of understanding, awareness, and impact on taxpayer behaviour as well as the collection of government taxes. An analysis of the relationship between taxpayer compliance and tax knowledge, awareness, and penalties is carried out through the use of descriptive and verification techniques in a quantitative research. Taxpayers of KPP Pratama Bandung Cicadas will be surveyed to determine the extent to which tax knowledge, awareness, and penalties influence compliance. This is done without comparing or linking the factors. Slovin was used to extract 100 taxpayers from a total of 300,740. We use quantitative and descriptive statistics. Tax compliance and tax policy should be improved as a result of this study. According to the research, people who are more aware of the tax rules are better able to pay their taxes. Enforcing tax rules through the use of tax penalties increases taxpayer understanding. According to the results of the research, the increase in taxpayer compliance at the Bandung Cicadas Primary Tax Service Office can be attributed to increased tax knowledge, awareness, and penalties. Given that these three factors statistically influence taxpayer compliance, it is important to study them together. Tax education, taxpayer awareness, and the effectiveness of tax penalties are some of the recommendations made in the study to increase taxpayer compliance

Problema ai minimi quadrati applicato alla regressione lineare: studio di casi applicativi

La regressione lineare è un metodo statistico utilizzato per predire i valori di una o più variabili dipendenti, dette 'risposte', da una collezione di valori di variabili indipendenti, dette 'predittori'. Trova applicazione in svariati ambiti, quali, ad esempio, l'ingegneria, la biologia, l'economia, ed è così largamente diffuso in quanto si traduce in un normale problema ai minimi quadrati. In questa tesi viene presentato il modello di regressione lineare multivariata e vengono esposti i suoi aspetti teorici, evidenziandone le proprietà qualitative e la sua riconducibilità ad un problema di minimi quadrati. Vengono presentati il problema ai minimi quadrati ed alcuni suoi risultati generali, seguiti dalla descrizione dei metodi numerici utilizzati per la sua risoluzione. Infine, vengono analizzati sperimentalmente due set di dati noti in letteratura, ricorrendo ai metodi numerici adatti a risolvere un problema di minimi quadrati e sottolineando quale sia quello più efficiente