Body fat assessment by bioelectrical impedance and its correlation with different anatomical sites used in the measurement of waist circumference in children

OBJECTIVE: To compare the different anatomical sites used in the measurement of waist circumference, as well as the effectiveness of these landmarks to predict the percentage of body fat by tetrapolar bioelectrical impedance analysis. METHODS: We evaluated 205 children from 6 to 9 years of age of both sexes. Data on weight, height and waist circumference were collected at three different sites: at the lower abdominal curvature, above the navel and at the midpoint between the last rib and the iliac crest. Nutritional status was assessed through the body mass index (BMI)/age as recommended by the World Health Organization. RESULTS: The sample was considered homogeneous in terms of sex, and the mean age was 7.2±1.2 years. Regarding nutritional status, 6.3% of the children had low weight, 75.1% were eutrophic, 7.3% were overweight, and 11.2% were obese. Among males, there was no statistical difference between the different sites of measurement; in females, the measurement above the navel was statistically higher. In the correlation analysis, the midpoint measurement showed the best correlation with percentage of body fat, with values of 0.50 in boys and 0.62 in girls. CONCLUSION: Waist circumference measured at the midpoint between the last rib and the iliac crest presented the best correlation with percentage of body fat.OBJETIVO: Comparar os diferentes pontos anatômicos de medida da circunferência da cintura, bem como a eficácia desses locais em predizer o percentual de gordura corporal mensurado pela bioimpedância elétrica tetrapolar. MÉTODOS: Foram avaliadas 205 crianças de 6 a 9 anos de idade de ambos os sexos. Foram coletados dados de peso, estatura e circunferência da cintura em três locais diferentes: na menor curvatura abdominal, sobre a cicatriz umbilical e no ponto médio entre a última costela e crista ilíaca. A avaliação do estado nutricional foi realizada a partir do índice de massa corporal/idade recomendado pela Organização Mundial de Saúde. RESULTADOS: No presente estudo houve homogeneidade entre os sexos, e a idade média foi de 7,2±1,2 anos. Em relação ao estado nutricional, 6,3% das crianças apresentaram baixo peso, 75,1% eram eutróficas, 7,3% apresentaram sobrepeso e 11,2% obesidade. No sexo masculino não houve diferença estatística entre os diferentes locais de medida. No feminino, a medida sobre a cicatriz umbilical foi estatisticamente maior. Na análise de correlação, a circunferência medida no ponto médio foi a que obteve melhor correlação com o percentual de gordura corporal, com valores de 0,50 nos meninos e 0,62 nas meninas. CONCLUSÃO: A circunferência da cintura medida no ponto médio entre a crista ilíaca e ultima costela foi a que apresentou melhor correlação com o percentual de gordura corporal.Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Universidade Federal de ViçosaUniversidade Federal de São Paulo (UNIFESP)UFVUNIFESPUNIFESPSciEL

A busca de assistência à saúde em serviços de pronto atendimento por mulheres adultas Health care search by adult women in emergency care services

Objetivo: Conhecer o comportamento de saúde de mulheres e os motivos para buscar assistência em um pronto atendimento. Método: Estudo descritiva e exploratória, de natureza qualitativa com 18 mulheres atendidas em um pronto atendimento municipal no noroeste do Paraná. Os dados foram coletados em novembro de 2015 por entrevista semiestruturada e submetidos à análise de conteúdo, modalidade temática. Resultados: Foram identificadas duas categorias empíricas: “Comportamentos de mulheres diante de intercorrências na saúde”, mostra que as condutas iniciais das mulheres, em situações de adoecimento, são automedicação e protelamento em procurar serviços de saúde; e “Motivos para procurar o serviço de pronto atendimento”, onde identificou-se que a procura deste nível de atendimento é motivada pela percepção de maior resolutividade, eficácia e agilidade, além de proximidade do lar. Conclusão: É comum às mulheres retardarem a procura por atendimento em virtude das responsabilidades inerentes ao gênero, e quando o fazem, preferem serviços mais resolutivos. Descritores: Serviços de Saúde; Assistência Ambulatorial; Saúde da Mulher

On the application of 3d metals for C-H activation toward bioactive compounds: The key step for the synthesis of silver bullets

Several valuable biologically active molecules can be obtained through C-H activation processes. However, the use of expensive and not readily accessible catalysts complicates the process of pharmacological application of these compounds. A plausible way to overcome this issue is developing and using cheaper, more accessible, and equally effective catalysts. First-row transition (3d) metals have shown to be important catalysts in this matter. This review summarizes the use of 3d metal catalysts in C-H activation processes to obtain potentially (or proved) biologically active compounds

A busca de assistência à saúde em serviços de pronto atendimento por mulheres adultas Health care search by adult women in emergency care services

Objetivo: Conhecer o comportamento de saúde de mulheres e os motivos para buscar assistência em um pronto atendimento. Método: Estudo descritiva e exploratória, de natureza qualitativa com 18 mulheres atendidas em um pronto atendimento municipal no noroeste do Paraná. Os dados foram coletados em novembro de 2015 por entrevista semiestruturada e submetidos à análise de conteúdo, modalidade temática. Resultados: Foram identificadas duas categorias empíricas: “Comportamentos de mulheres diante de intercorrências na saúde”, mostra que as condutas iniciais das mulheres, em situações de adoecimento, são automedicação e protelamento em procurar serviços de saúde; e “Motivos para procurar o serviço de pronto atendimento”, onde identificou-se que a procura deste nível de atendimento é motivada pela percepção de maior resolutividade, eficácia e agilidade, além de proximidade do lar. Conclusão: É comum às mulheres retardarem a procura por atendimento em virtude das responsabilidades inerentes ao gênero, e quando o fazem, preferem serviços mais resolutivos.Descritores: Serviços de Saúde; Assistência Ambulatorial; Saúde da Mulher

Tropical peat as a versatile material for solid-phase extraction of pesticides from medicinal plant Cordia salicifolia

Natural peat was tested for solid-phase extraction of acephate, chlorpropham, pirimicarb, bifenthrin, tetradifon and phosalone from the medicinal plant Cordia salicifolia, using gas chromatography-mass spectrometry with selected ion monitoring (GC/MS, SIM). Considering that there are no Brazilian regulations concerning maximum permissible pesticide residue concentrations in medicinal herbs, recovery experiments were carried out (three replicates) at two arbitrary fortification levels (0.5 and 1.0 mg kg-1), resulting in recoveries ranging from 64% to 118% and relative standard deviations between 5.6% and 26.4% for peat sorbent. Detection and quantification limits for herb ranged from 0.10 to 0.15 mg kg-1 and from 0.15 to 0.25 mg kg-1, respectively, for the different pesticides studied. The developed method was linear over the range assayed, 0.1-5.0 μg g-1, with correlation coefficients ranging from 0.9975 to 0.9986 for all pesticides. Comparison between natural peat and conventional sorbent (neutral alumina) showed similar performance of peat for the six pesticides tested

Hyperendemicity, heterogeneity and spatial overlap of leprosy and cutaneous leishmaniasis in the southern Amazon region of Brazil

Neglected tropical diseases characterized by skin lesions are highly endemic in the state of Mato Grosso, Brazil. We analyzed the spatial distribution of leprosy and Cutaneous Leishmaniasis (CL) and identified the degree of overlap in their distribution. All new cases of leprosy and CL reported between 2008 and 2017 through the national reporting system were included in the study. Scan statistics together with univariate Global and Local Moran's I were employed to identify clusters and spatial autocorrelation for each disease, with the spatial correlation between leprosy and CL measured by bivariate Global and Local Moran's I. Finally, we evaluated the demographic characteristics of the patients. The number of leprosy (N = 28,204) and CL (N = 24,771) cases in Mato Grosso and the highly smoothed detection coefficients indicated hyperendemicity and spatial distribution heterogeneity. Scan statistics demonstrated overlap of high-risk clusters for leprosy (RR = 2.0; P <0.001) and CL (RR = 4.0; P <0.001) in the North and Northeast mesoregions. Global Moran's I revealed a spatial autocorrelation for leprosy (0.228; P = 0.001) and CL (0.311; P = 0.001) and a correlation between them (0.164; P = 0.001). Both diseases were found to be concentrated in urban areas among men aged 31-60 years, of brown-skinned ethnicity and with a low educational level. Our findings indicate a need for developing integrated and spatially as well as socio-demographically targeted public health policies

BioTIME: A database of biodiversity time series for the Anthropocene.

MotivationThe BioTIME database contains raw data on species identities and abundances in ecological assemblages through time. These data enable users to calculate temporal trends in biodiversity within and amongst assemblages using a broad range of metrics. BioTIME is being developed as a community-led open-source database of biodiversity time series. Our goal is to accelerate and facilitate quantitative analysis of temporal patterns of biodiversity in the Anthropocene.Main types of variables includedThe database contains 8,777,413 species abundance records, from assemblages consistently sampled for a minimum of 2 years, which need not necessarily be consecutive. In addition, the database contains metadata relating to sampling methodology and contextual information about each record.Spatial location and grainBioTIME is a global database of 547,161 unique sampling locations spanning the marine, freshwater and terrestrial realms. Grain size varies across datasets from 0.0000000158 km2 (158 cm2) to 100 km2 (1,000,000,000,000 cm2).Time period and grainBioTIME records span from 1874 to 2016. The minimal temporal grain across all datasets in BioTIME is a year.Major taxa and level of measurementBioTIME includes data from 44,440 species across the plant and animal kingdoms, ranging from plants, plankton and terrestrial invertebrates to small and large vertebrates.Software format.csv and .SQL

Low-Level Laser Application in the Early Myocardial Infarction Stage Has No Beneficial Role in Heart Failure

Low-level laser therapy (LLLT) has been targeted as a promising approach that can mitigate post infarction cardiac remodeling. There is some interesting evidence showing that the beneficial role of the LLLT could persist long-term even after the end of the application, but it remains to be systematically evaluated. Therefore, the present study aimed to test the hypothesis that LLLT beneficial effects in the early post-infarction cardiac remodeling could remain in overt heart failure even with the disruption of irradiations. Female Wistar rats were subjected to the coronary occlusion to induce myocardial infarction or Sham operation. A single LLLT application was carried out after 60 s and 3 days post-coronary occlusion, respectively. Echocardiography was performed 3 days and at the end of the experiment (5 weeks) to evaluate cardiac function. After the last echocardiographic examination. LV hemodynamic evaluation was performed at baseline and on sudden afterload increases. Compared with the Sham group, infarcted rats showed increased systolic and diastolic internal diameter as well as a depressed shortening fraction of LV. The only benefit of the LLLT was a higher shortening fraction after 3 days of infarction. However, treated-LLLT rats show a lower shortening fraction in the 5th week of study when compared with Sham and non-irradiated rats. A worsening of cardiac function was confirmed in the hemodynamic analysis as evidenced by the higher LV end-diastolic pressure and lower +dP/dt and dP/dt with five weeks of study. Cardiac functional reserve was also impaired by infarction as evidenced by an attenuated response of stroke work index and cardiac output to a sudden afterload stress, without LLLT repercussions. No significant differences were found in the myocardial expression of Akti NEGF pathway. Collectively, these findings illustrate that LLLT improves LV systolic function in the early post-infarction cardiac remodeling. However, this beneficial effect may be dependent on the maintenance of phototherapy. Long-term studies with LLLT application are needed to establish whether these effects ultimately translate into improved cardiac remodeling.Conselho Nacional de Desenvolvimento Cientifico e TecnologicoFAPESPNove de Julho Univ, Lab Biophoton, Sao Paulo, SP, BrazilUniv Fed Sao Paulo, Lab Cardiac Physiol, Sao Paulo, SP, BrazilNove de Julho Univ, Program Med, Sao Paulo, BrazilUniv Sao Judas Tadeu, Brazil Phys Educ & Aging Sci Program, Translat Physiol Lab, Sao Paulo, BrazilUniv Fed Sao Paulo, Lab Cardiac Physiol, Sao Paulo, SP, BrazilCNPq: 4400851/2014-8FAPESP: 09-54225/8FAPESP: 15/11028-9Web of Scienc

Satietogenic Protein from Tamarind Seeds Decreases Food Intake, Leptin Plasma and CCK-1r Gene Expression in Obese Wistar Rats

Objective: This study evaluated the effect of a protein, the isolated Trypsin Inhibitor (TTI) from Tamarindus indica L. seed, as a CCK secretagogue and its action upon food intake and leptin in obese Wistar rats. Methods: Three groups of obese rats were fed 10 days one of the following diets: Standard diet (Labina®) + water; High Glycemic Index and Load (HGLI) diet + water or HGLI diet + TTI. Lean animals were fed the standard diet for the 10 days. Food intake, zoometric measurements, plasma CCK, plasma leptin, relative mRNA expression of intestinal CCK-related genes, and expression of the ob gene in subcutaneous adipose tissue were assessed. Results: TTI decreased food intake but did not increase plasma CCK in obese animals. On the other hand, TTI treatment decreased CCK-1R gene expression in obese animals compared with the obese group with no treatment (p = 0.027). Obese animals treated with TTI presented lower plasma leptin than the non-treated obese animals. Conclusion: We suggest that TTI by decreasing plasma leptin may improve CCK action, regardless of its increase in plasma from obese rats, since food intake was lowest