Evidence of non-selective lexical access to second and third language in unbalanced multilinguals: an N400 study on the processing of interlingual homographs

Bilinguals and multilinguals commonly encounter words in their multiple languages which share some linguistic aspects. Among those are interlingual homographs, or words that have the exact same orthography in two different languages. The current study examined, through a semantic judgment task in English with ERP recording, how multilinguals (speakers of Brazilian Portuguese, English and German) accessed the meanings of interlingual homographs that belonged to their dominant and non-dominant foreign languages compared to a control group of Brazilian Portuguese-English bilinguals. The findings demonstrated that multilinguals were slower to respond to the English-German interlingual homographs as compared to control stimuli (no homographs). The results also demonstrated that, when the interlingual homographs were semantically related to their targets in the non-target language, there were significantly more errors and a higher RT than in unrelated conditions. Additionally, only the bilinguals presented the typical N400 effect for unrelated conditions, suggesting that the co-activation of the non-target language due to interlingual homographs modulated this ERP in the multilingual group. Our results provide support for the Bilingual Interactive Activation plus model and suggest that literature findings on interference between first and second languages also hold for second and third languages.Bilinguals and multilinguals commonly encounter words in their multiple languages which share some linguistic aspects. Among those are interlingual homographs, or words that have the exact same orthography in two different languages. The current study examined, through a semantic judgment task in English with ERP recording, how multilinguals (speakers of Brazilian Portuguese, English and German) accessed the meanings of interlingual homographs that belonged to their dominant and non-dominant foreign languages compared to a control group of Brazilian Portuguese-English bilinguals. The findings demonstrated that multilinguals were slower to respond to the English-German interlingual homographs as compared to control stimuli (no homographs). The results also demonstrated that, when the interlingual homographs were semantically related to their targets in the non-target language, there were significantly more errors and a higher RT than in unrelated conditions. Additionally, only the bilinguals presented the typical N400 effect for unrelated conditions, suggesting that the co-activation of the non-target language due to interlingual homographs modulated this ERP in the multilingual group. Our results provide support for the Bilingual Interactive Activation plus model and suggest that literature findings on interference between first and second languages also hold for second and third languages.Bilinguals and multilinguals commonly encounter words in their multiple languages which share some linguistic aspects. Among those are interlingual homographs, or words that have the exact same orthography in two different languages. The current study examined, through a semantic judgment task in English with ERP recording, how multilinguals (speakers of Brazilian Portuguese, English and German) accessed the meanings of interlingual homographs that belonged to their dominant and non-dominant foreign languages compared to a control group of Brazilian Portuguese-English bilinguals. The findings demonstrated that multilinguals were slower to respond to the English-German interlingual homographs as compared to control stimuli (no homographs). The results also demonstrated that, when the interlingual homographs were semantically related to their targets in the non-target language, there were significantly more errors and a higher RT than in unrelated conditions. Additionally, only the bilinguals presented the typical N400 effect for unrelated conditions, suggesting that the co-activation of the non-target language due to interlingual homographs modulated this ERP in the multilingual group. Our results provide support for the Bilingual Interactive Activation plus model and suggest that literature findings on interference between first and second languages also hold for second and third languages.Bilinguals and multilinguals commonly encounter words in their multiple languages which share some linguistic aspects. Among those are interlingual homographs, or words that have the exact same orthography in two different languages. The current study examined, through a semantic judgment task in English with ERP recording, how multilinguals (speakers of Brazilian Portuguese, English and German) accessed the meanings of interlingual homographs that belonged to their dominant and non-dominant foreign languages compared to a control group of Brazilian Portuguese-English bilinguals. The findings demonstrated that multilinguals were slower to respond to the English-German interlingual homographs as compared to control stimuli (no homographs). The results also demonstrated that, when the interlingual homographs were semantically related to their targets in the non-target language, there were significantly more errors and a higher RT than in unrelated conditions. Additionally, only the bilinguals presented the typical N400 effect for unrelated conditions, suggesting that the co-activation of the non-target language due to interlingual homographs modulated this ERP in the multilingual group. Our results provide support for the Bilingual Interactive Activation plus model and suggest that literature findings on interference between first and second languages also hold for second and third languages

Brazilian version of the Cornell depression scale in dementia

OBJECTIVE: Translating and adapting the Cornell scale for depression in dementia to the Portuguese language and verifying the interrater and test-retest reliability of the translated and adapted version. METHOD: The Cornell scale was translated into Portuguese and back translated into English. Divergences of translation were identified and discussed, resulting in a version which was submitted to a pre-test for cross-cultural adaptation. The final version was administered to a sample of 29 patients with probable AD and to their caregivers. RESULTS: The Cornell Scale presented good interrater (Kappa=0,77; p<0,001) and test-retest reliability (Kappa=0,76; p<0,001). The final version was easy to administer and well understood by the caregivers. CONCLUSION: The Brazilian version of the Cornell Scale is an instrument with good reliability to evaluate depression in patients with dementia. This tool will contribute to the evaluation and follow-up of depressed patients with dementia in our population and may also be used in multicentric studies with Brazilian population.OBJETIVO: Tradução e adaptação da escala Cornell de depressão em demência e verificação da confiabilidade entre e intra-examinadores da versão na língua portuguesa. MÉTODO: A versão original da Escala Cornell foi traduzida para o português por firma especializada em tradução de textos médicos e retrotraduzida para o inglês por outros dois tradutores independentes. As divergências de tradução foram identificadas e discutidas, chegando-se à versão que foi submetida à pré-teste para adaptação sócio-cultural. Após esta adaptação, obteve-se a versão final que foi administrada a amostra de 29 pacientes com doença de Alzheimer provável e aos seus cuidadores. RESULTADOS: A versão final da escala mostrou-se de fácil aplicação e obteve boa confiabilidade intra-examinador (Kappa=0,77; p<0,001) e entre-examinadores (Kappa=0,76; p<0,001). CONCLUSÃO: A versão brasileira da Escala Cornell é um instrumento que pode ser utilizado para avaliação e acompanhamento de depressão em pacientes com demência.Universidade de São Paulo Faculdade de Medicina Hospital das ClínicasUniversidade Federal de São Paulo (UNIFESP) Escola de Paulista de Medicina Departamento de Neurologia e NeurocirurgiaUNIFESP, Escola de Paulista de Medicina Depto. de Neurologia e NeurocirurgiaSciEL

Free recall of bound information held in short-term memory is unimpaired by age and education

Objectives: It has been challenging to identify cognitive markers to differentiate healthy brain aging from neurodegeneration due to Alzheimer’s disease (AD) that are not affected by age and education. The Short-Term Memory Binding (STMB) showed not to be affected by age or education when using the change detection paradigm. However, no previous study has tested the effect of age and education using the free recall paradigm of the STMB. Therefore, the objective of this study was to investigate age and education effects on the free recall version of the STMB test under different memory loads. Methods: 126 healthy volunteers completed the free recall STMB test. The sample was divided into five age bands and into five education bands for comparisons. The STMB test assessed free recall of two (or three) common objects and two (or three) primary colors presented as individual features (unbound) or integrated into unified objects (bound). Results: The binding condition and the larger set size generated lower free recall scores. Performance was lower in older and less educated participants. Critically, neither age nor education modified these effects when compared across experimental conditions (unbound versus bound features). Conclusions: Binding in short-term memory carries a cost in performance. Age and education do not affect such a binding cost within a memory recall paradigm. These findings suggest that this paradigm is a suitable cognitive marker to differentiate healthy brain aging from age-related disease such as AD

Recalling feature bindings differentiates Alzheimer’s disease from Frontotemporal Dementia

It has been challenging to identify clinical cognitive markers that can differentiate patients with Alzheimer’s disease (AD) from those with behavioral variant frontotemporal dementia (bvFTD). The Short-term Memory Binding (STMB) test assesses the ability to integrate colors and shapes into unified representations and to hold them temporarily during online performance. The objective of this study is to investigate whether free recall deficits during short-term memory binding (STMB) test can differentiate patients with AD from those with bvFTD and controls. Participants were 32 cognitively intact adults, 35 individuals with AD and 18 with bvFTD. All patients were in the mild dementia stage. Receiver-operating characteristics (ROC) analyses were used to examine the diagnostic accuracy of the STMB. The results showed that AD patients performed significantly worse than controls and bvFTD patients in the STMB test, while the latter groups showed equivalent performance. The bound condition of the STMB test showed an AUC of 0.853, with 84.4% of sensitivity and 80% of specificity to discriminate AD from controls and an AUC of 0.794, with 72.2% of sensitivity and 80% of specificity to differentiate AD from bvFTD. Binding deficits seem specific to AD. The free recall version of the STMB test can be used for clinical purposes and may aid in the differential diagnosis of AD. Findings support the view that the STMB may be a suitable cognitive marker for AD

Avaliação cognitiva, comportamental e funcional : doença de Alzheimer

A review of the evidence on cognitive, functional and behavioral assessment for the diagnosis of dementia due to Alzheimer’s disease (AD) is presented with revision and broadening of the recommendations on the use of tests and batteries in Brazil for the diagnosis of dementia due to AD. A systematic review of the literature (MEDLINE, LILACS and SCIELO database) was carried out by a panel of experts. Studies on the validation and/or adaptation of tests, scales and batteries for the Brazilian population were analyzed and classified according to level of evidence. There were sufficient data to recommend the IQCODE, DAFS-R, DAD, ADL-Q and Bayer scale for the evaluation of instrumental activities of daily living, and the Katz scale for the assessment of basic activities of daily living. For the evaluation of neuropsychiatric symptoms, the Neuropsychiatric Inventory (NPI) and the CAMDEX were found to be useful, as was the Cornell scale for depression in dementia. The MiniMental State Examination has clinical utility as a screening test, as do the multifunctional batteries (CAMCOG-R, ADAS-COG, CERAD and MDRS) for brief evaluations of several cognitive domains. There was sufficient evidence to recommend the CDR scale for clinical and severity assessment of dementia. Tests for Brazilian Portuguese are recommended by cognitive domain based on available data.Este artigo apresenta revisão e ampliação das recomendações sobre os testes e baterias empregados no Brasil para o diagnóstico e avaliação cognitiva, funcional e comportamental da demência na doença de Alzheimer (DA). De modo sistemático foi revista a literatura disponível (nas bases MEDLINE, LILACS e SCIELO) e os artigos foram avaliados e classificados por níveis de evidência, para se estabelecerem as recomendações. Para a avaliação funcional a recomendação é o uso das escalas IQCODE, DAFS-R, DAD, ADL-Q e Bayer para avaliação das atividades instrumentais da vida diária e escala Katz para avaliação das atividades básicas. Para avaliação dos sintomas neuropsiquiátricos foram recomendadas as escalas NPI e CAMDEX e a Cornell para depressão em demência. Como instrumento de rastreio deve-se utilizar o Mini-Exame do Estado Mental; quanto às baterias multifuncionais, pode-se aplicar CAMCOG-R, ADAS-COG, CERAD e MDRS, que avaliam brevemente várias funções cognitivas. Para avaliação clínica da demência e classificação de acordo com a gravidade é recomendada a escala CDR. São recomendados os testes por domínio cognitivo baseados nas evidências disponíveis para uso na nossa língua

Desempenho de uma população brasileira no teste de alfabetização funcional para adultos na área de saúde

OBJECTIVE: To analyze the scoring obtained by an instrument, which evaluates the ability to read and understand items in the health care setting, according to education and age. METHODS: The short version of the Test of Functional Health Literacy in Adults was administered to 312 healthy participants of different ages and years of schooling. The study was conducted between 2006 and 2007, in the city of São Paulo, Southeastern Brazil. The test includes actual materials such as pill bottles and appointment slips and measures reading comprehension, assessing the ability to read and correctly pronounce a list of words and understand both prose passages and numerical information. Pearson partial correlations and a multiple regression model were used to verify the association between its scores and education and age. RESULTS: The mean age of the sample was 47.3 years(sd=16.8) and the mean education was 9.7 years(sd=5; range: 1 - 17). A total of 32.4% of the sample showed literacy/numeracy deficits, scoring in the inadequate and marginal functional health literacy ranges. Among the elderly (65 years or older) this rate increased to 51.6%. There was a positive correlation between schooling and scores (r=0.74; pOBJETIVO: Analizar los escores de instrumento que evalúa habilidad de lectura y comprensión de materiales del área de salud según escolaridad y edad. MÉTODOS: Fueron evaluados 312 participantes saludables de diferentes edades por medio de la versión reducida del instrumento Test of Functional Health Literacy in Adults. El estudio fue realizado entre 2006 y 2007 en la ciudad de Sao Paulo (Sureste de Brasil). El instrumento incluye materiales como frascos de medicamentos y cartones de para marcar consultas, evaluando la comprensión de lectura y de conceptos numéricos. Las pruebas de correlación parcial y de Pearson y un modelo de regresión múltiple fueron usados para verificar la asociación entre los escores en el instrumento, escolaridad y edad. RESULTADOS: Los promedios de edad y de escolaridad de la muestra fueron respectivamente 47,3 (dp=16,8) y 9,7 (dp=5; de uno a 17 años de estudio). El total de 32,4% de la muestra mostraron déficit de alfabetización funcional/uso de conceptos numéricos en el área de salud, con desempeño inadecuado o limítrofe en el instrumento. Entre ancianos (65 años o más) esta tasa afectó 51,6%. Se encontró correlación positiva entre años de estudio y escores en el instrumento (r=0,740; p< 0,01) y correlación negativa entre edad y escores en el instrumento (r=-0,259; p< 0,01).La correlación entre escores en el instrumento y edad no fue significativa cuando los efectos de la escolaridad fueron controlados (r=-0,031, p=0,584). Una asociación significativa (B=3,877, Beta=0,733; p< 0,001) fue encontrada entre años de estudio y escores en el instrumento. La edad no fue una variable predictiva en el modelo (B=-0,035, Beta=-0,22; p=0,584). CONCLUSIONES: El instrumento es adecuado para evaluar la alfabetización funcional en salud en la población brasilera. El elevado número de individuos clasificados como analfabetos funcionales indica la importancia de adopción de medidas especiales para ayudar estos individuos a comprender correctamente las orientaciones para cuidados de salud.OBJETIVO: Analisar os escores de instrumento que avalia habilidade de leitura e compreensão de materiais da área da saúde segundo escolaridade e idade. MÉTODOS: Foram avaliados 312 participantes saudáveis de diferentes idades por meio da versão reduzida do instrumento Test of Functional Health Literacy in Adults. O estudo foi realizado entre 2006 e 2007 na cidade de São Paulo (SP). O instrumento envolve materiais como frascos de medicamentos e cartões de agendamento de consultas, avaliando a compreensão de leitura e de conceitos numéricos. Os testes de correlação parcial e de Pearson e um modelo de regressão múltipla foram usados para verificar a associação entre os escores no instrumento, escolaridade e idade. RESULTADOS: As médias de idade e de escolaridade da amostra foram respectivamente 47,3 (dp=16,8 ) e 9,7 (dp=5; de um a 17 anos de estudo). O total de 32,4% da amostra mostraram déficits de alfabetização funcional/ uso de conceitos numéricos na área de saúde, com desempenho inadequado ou limítrofe no instrumento. Entre idosos (65 anos ou mais) esta taxa atingiu 51,6%. Encontrou-se correlação positiva entre anos de estudo e escores no instrumento (r=0,740;

Diagnosis and rehabilitation attempt of a patient with acquired dyslexia

Abstract Although dyslexia is a common consequence of brain damage there are few studies about the rehabilitation of this disorder. Cognitive Neuropsychology models of reading have been used to describe several syndromes of acquired dyslexia. Phonological dyslexia is a reading disorder characterized by a dysfunctional grapheme-to-phoneme conversion procedure, which affects the ability to read low frequency words and nonwords. Lexical reading is preserved and patients can read frequent words (regular and irregular). Objective: Verify the application of the cognitive model in the characterization of the reading disorder of a patient with acquired dyslexia and in the devising and implementation of a rehabilitation plan. Methods: This study presents OCS, a 57-year-old patient who suffered from acquired phonological dyslexia after a left temporo-parietooccipital ischemic stroke. A rehabilitation program based on the principles of Cognitive Neuropsychology was devised non-words and low frequency words with controlled lengths were used and the patient was stimulated to read them aloud in a 22-session treatment. Results: The post-test evaluation showed quantitative and qualitative improvements Significant improvements were verified in the total number of correct responses including self-correction attempts (p<0.01) and in the reading of trisyllabic and polysyllabic non-words of simple syllabic structure (p=0.0007 and p=0.02 respectively). Conclusions: The use of the cognitive model to devise a rehabilitation program was successful and we observed significant improvement of reading skills in a short period of treatment. The achievements over this period provided the patient with functional reading performance

Acesso Lexical na Leitura: Síntese de achados a partir de estudos de rastreamento ocular e suas implicações para a alfabetização

This article aims to present the word visual recognition and lexical access in reading by both describing the steps of this process and integrating it into the knowledge resulting from the studies of Cognitive Psychology (models explaining the word reading processing) as well as from Psycholinguistics (evaluating the linguistics variables which affect lexical processing) focusing on the results obtained by the eye-tracking technology. The steps of the visual information recognition (orthographic processing), and the access to the phonological, morphological, and semantic levels of the word processing, are synthesized and discussed. This synthesis, comprising examples and graphic schemata, is intended to facilitate the access of this information to educators working with literacy. It also shows the skilled readers' cognitive processes to recognize and pronounce the words individually. It starts by outlining the work of the eyes during the reading process, focusing on the words of a sentence, and their relation to eye movements covering the written material, besides specifying how eye-trackers register the oculomotor movements. Next, it describes the sublexical and lexical processes of word processing, presenting two theoretical models (Dual Route Cascade and Iterative Model of the perceptual process) until the word is integrated into the sentence and the discourse.Este artigo tem como objetivo apresentar o reconhecimento visual da palavra e o acesso lexical na leitura, descrevendo as etapas desse processo e integrando o conhecimento proveniente de estudos da Psicologia Cognitiva (modelos que explicam o processamento de leitura de palavras) e da Psicolinguística (que avaliam as variáveis linguísticas que afetam o processamento lexical), focalizando os achados obtidos por meio da técnica de rastreamento ocular. As etapas de reconhecimento da informação gráfica (processamento ortográfico) bem como o acesso aos aspectos fonológico, morfológico e semântico do processamento da palavra são sintetizado e discutido. Pretende-se que esta síntese, que inclui exemplos e esquemas gráficos, possa facilitar o acesso dessa informação por educadores envolvidos na alfabetização. O artigo traz os processos cognitivos que leitores proficientes usam a fim de reconhecer e pronunciar palavras individualmente. Ele contempla primeiramente o trabalho dos olhos durante a leitura, focando nas palavras de uma sentença, e a relação do movimento ocular com a materialidade linguística, além de especificar como o rastreador ocular registra o comportamento dos olhos. Em seguida discorre sobre os processos sublexicais e lexicais do processamento da palavra, apresentando dois modelos teóricos (Modelo Iterativo de Percepção e o Modelo de Dupla Rota em Cascata.), até a integração da palavra à sentença e ao discurso

Does Language Distance Modulate the Contribution of Bilingualism to Cognitive Reserve in Seniors? A Systematic Review.

Peer reviewed: TrueWe report a systematic review and exploratory meta-regression investigating the hypothesis that the effects of bilingualism on cognitive reserve are modulated by the distance between the pair of languages a bilingual uses. An inclusive multiple database search was performed in order to identify all relevant published research conducted in bilingual seniors. A combination of qualitative and quantitative synthesis methods were used in order to investigate our research questions. Results suggest that healthy bilingual seniors speaking more distant language pairs show improved monitoring performance on cognitive tasks. Evidence regarding a modulatory influence of language distance (LD) on the age of dementia diagnosis was inconclusive due to the small number of published studies meeting our inclusion criteria. We recommend more detailed reporting of individual differences in bilingual experience to assess the impact of LD and other variables on typical cognitive aging and the development of dementia. Linguistic differences in samples should also be considered as a constraint on bilingual advantages in future studies. Preregistration: PROSPERO CRD42021238705; OSF DOI 10.17605/OSF.IO/VPRBU