Business begins at home

One of the most significant trends in the post-industrial era has been for the home to become an important focus for work. The boundaries between work and home are now increasingly blurred, reversing the forces of the industrial era in which places deemed suitable for each were clearly demarcated and physically separate. The most recent published figures available from the Labour Force Survey (2005)1 indicate that 3.1m people now work mainly from home, 11% of the workforce. This represents a rise from 2.3m in 1997 (9% of the workforce), a 35% increase. The majority of homeworkers (2.4m or 77% of the total) are 'teleworkers' – people who use computers and telecommunications to work at home. The number of teleworkers has increased by 1.5m between 1997 and 2005, a 166% increase. Clearly, it is the growth in the number of teleworkers which is driving the increase in homeworking

The value of emergency medicine placements for postgraduate doctors: views of Foundation Year 2 doctors and training leads in the emergency department (ED)

Objectives: To examine the delivery of postgraduate training in the emergency medicine setting and its impact on postgraduate doctor (Foundation Year 2) performance and competence. Methods: A national study in four emergency departments (EDs) in England between 2009 and 2010 was undertaken. Semistructured interviews with ED training leads (TLs) and focus groups with Foundation Year 2 (F2) doctors were carried out in each ED. Interviews and focus group data were analysed to compare the perspectives of F2 doctors and TLs on the delivery of training and performance and confidence of F2 doctors. Results: Interviews were carried out with eight TLs and focus groups with 30 F2s. F2 doctors and EDTLs agreed that ED was a valuable environment for F2 doctors to develop their competence, with exposure to a broad range of patients and the opportunity to make decisions about clinical care. Diverging views existed around competence and performance of F2s. F2 doctors had anxieties about decision-making (particularly discharging patients) and required regular feedback to feel confident in their care. TLs recognised a need for more supervision and support for F2 doctors but this was challenging in a busy, performance-led service. Conclusions: Emergency medicine placements were important in the development of confident and competent F2 doctors, particularly in the context of less clinical exposure in other specialty placements. However, there are competing tensions between elements of postgraduate learning and service delivery within emergency medicine that require addressing to enable trainees to optimally develop knowledge and skills in this environment

Perceptions and experience of employment regulation in UK small firms

The view that excessive regulation constrains small business growth has been a persistent theme within business and policy communities, although recent studies have demonstrated the actual effects of regulation to be relatively modest. A prior small-scale study proposed four reasons why employment legislation does 'not damage' small firms. We attempt to assess the robustness of these propositions in a large-scale survey of 16 779 small firms. Results provide empirical support for three propositions. Firstly, perceived dissatisfaction masks actual effects. Secondly, competitive conditions mediate regulatory effects; however, even resource-constrained firms reported few negative effects. Thirdly, informality eases regulatory impact. Results failed to confirm that older laws are 'routinised'. Length of time as a business owner was found to be more influential than age of regulation, with owners who have been in business for many years having a longer 'window of exposure' increasing their likelihood of experiencing negative and positive effects

Finding AGN in Deep X-ray Flux States with Swift

We report on our ongoing project of finding Active Galactic Nuclei (AGN) that go into deep X-ray flux states detected by Swift. Swift is performing an extensive study on the flux and spectral variability of AGN using Guest Investigator and team fill-in programs followed by triggering XMM_Newton for deeper follow-up observations. So far this program has been very successful and has led to a number of XMM-Newton follow up observations, including Mkn 335, PG 0844+349, and RX J2340.8-5329. Recent analysis of new Swift AGN observations reveal several AGN went into a very low X-ray flux state, particularly Narrow-Line Seyfert 1 galaxies. One of these is RX J2317-4422, which dropped by a factor of about 60 when compared to the ROSAT All-Sky Survey.Comment: 6 pages, 3 figures, Proceedings of the "10 Years of Swift" Meeting held in Rome in December 2014. Submitted to Po

Child Acute Malnutrition and Mortality in Populations Affected by Displacement in the Horn of Africa, 1997–2009

Drought and conflict in the Horn of Africa are causing population displacement, increasing risks of child mortality and malnutrition. Humanitarian agencies are trying to mitigate the impact, with limited resources. Data from previous years may help guide decisions. Trends in different populations affected by displacement (1997–2009) were analyzed to investigate: (1) how elevated malnutrition and mortality were among displaced compared to host populations; (2) whether the mortality/malnutrition relation changed through time; and (3) how useful is malnutrition in identifying high mortality situations. Under-five mortality rates (usually from 90-day recall, as deaths/10,000/day: U5MR) and global acute malnutrition (wasting prevalences, < −2SDs of references plus edema: GAM) were extracted from reports of 1,175 surveys carried out between 1997–2009 in the Horn of Africa; these outcome indicators were analyzed by livelihood (pastoral, agricultural) and by displacement status (refugee/internally displaced, local resident/host population, mixed); associations between these indicators were examined, stratifying by status. Patterns of GAM and U5MR plotted over time by country and livelihood clarified trends and showed substantial correspondence. Over the period GAM was steady but U5MR generally fell by nearly half. Average U5MR was similar overall between displaced and local residents. GAM was double on average for pastoralists compared with agriculturalists (17% vs. 8%), but was not different between displaced and local populations. Agricultural populations showed increased U5MR when displaced, in contrast to pastoralist. U5MR rose sharply with increasing GAM, at different GAM thresholds depending on livelihood. Higher GAM cut-points for pastoralists than agriculturalists would better predict elevated U5MR (1/10,000/day) or emergency levels (2/10,000/day) in the Horn of Africa; cut-points of 20–25% GAM in pastoral populations and 10–15% GAM in agriculturalists are suggested. The GAM cut-points in current use do not vary by livelihood, and this needs to be changed, tailoring cut points to livelihood groups, to better identify priorities for intervention. This could help to prioritize limited resources in the current situation of food insecurity and save lives

Coffee Consumption and Cardiovascular Diseases: A Mendelian Randomization Study.

Coffee consumption has been linked to a lower risk of cardiovascular disease in observational studies, but whether the associations are causal is not known. We conducted a Mendelian randomization investigation to assess the potential causal role of coffee consumption in cardiovascular disease. Twelve independent genetic variants were used to proxy coffee consumption. Summary-level data for the relations between the 12 genetic variants and cardiovascular diseases were taken from the UK Biobank with up to 35,979 cases and the FinnGen consortium with up to 17,325 cases. Genetic predisposition to higher coffee consumption was not associated with any of the 15 studied cardiovascular outcomes in univariable MR analysis. The odds ratio per 50% increase in genetically predicted coffee consumption ranged from 0.97 (95% confidence interval (CI), 0.63, 1.50) for intracerebral hemorrhage to 1.26 (95% CI, 1.00, 1.58) for deep vein thrombosis in the UK Biobank and from 0.86 (95% CI, 0.50, 1.49) for subarachnoid hemorrhage to 1.34 (95% CI, 0.81, 2.22) for intracerebral hemorrhage in FinnGen. The null findings remained in multivariable Mendelian randomization analyses adjusted for genetically predicted body mass index and smoking initiation, except for a suggestive positive association for intracerebral hemorrhage (odds ratio 1.91; 95% CI, 1.03, 3.54) in FinnGen. This Mendelian randomization study showed limited evidence that coffee consumption affects the risk of developing cardiovascular disease, suggesting that previous observational studies may have been confounded

Hatch Dates, Growth, Survival, and Overwinter Mortality of Age‐0 Alewives in Lake Michigan: Implications for Habitat‐Specific Recruitment Success

Alewives Alosa pseudoharengus are key components of Laurentian Great Lakes ecosystems and spawn in multiple habitat types. Exploration of alewife early life history dynamics within these different habitats should help identify important recruitment processes. During 2001‐2003, we quantified physical (temperature, transparency) and biotic (chlorophyll a, zooplankton densities) habitat factors and collected age‐0 alewives (using ichthyoplankton nets and trawls) in a nearshore region of Lake Michigan and Muskegon Lake, Michigan (a drowned river mouth lake connected to Lake Michigan). We characterized alewife hatch dates, individual condition, growth, mortality, and size‐dependent overwinter survival to infer differences in habitat‐specific recruitment success. Temperature, turbidity, chlorophyll‐a concentrations, and densities of zooplankton prey were consistently higher in Muskegon Lake than in nearshore Lake Michigan. On average, young alewives in Muskegon Lake hatched earlier, grew faster, were in better condition (based on a biphasic length‐weight relationship), and had greater survival than alewives in Lake Michigan. By the end of the growing season, young alewives in Muskegon Lake obtained a larger size than those residing in nearshore Lake Michigan, suggesting that they were more likely to survive through winter (a period of intense size‐selective mortality) and ultimately recruit to the adult population.Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/141621/1/tafs1298.pd

Performance Qualification Test of the ISS Water Processor Assembly (WPA) Expendables

The Water Processor Assembly (WPA) for use on the International Space Station (ISS) includes various technologies for the treatment of waste water. These technologies include filtration, ion exchange, adsorption, catalytic oxidation, and iodination. The WPA hardware implementing portions of these technologies, including the Particulate Filter, Multifiltration Bed, Ion Exchange Bed, and Microbial Check Valve, was recently qualified for chemical performance at the Marshall Space Flight Center. Waste water representing the quality of that produced on the ISS was generated by test subjects and processed by the WPA. Water quality analysis and instrumentation data was acquired throughout the test to monitor hardware performance. This paper documents operation of the test and the assessment of the hardware performance

VenSAR on EnVision: taking Earth Observation radar to Venus

Venus should be the most Earth-like of all our planetary neighbours: its size, bulk composition and distance from the Sun are very similar to those of Earth. How and why did it all go wrong for Venus? What lessons can be learned about the life story of terrestrial planets in general, in this era of discovery of Earth-like exoplanets? Were the radically different evolutionary paths of Earth and Venus driven solely by distance from the Sun, or do internal dynamics, geological activity, volcanic outgassing and weathering also play an important part? EnVision is a proposed ESA Medium class mission designed to take Earth Observation technology to Venus to measure its current rate of geological activity, determine its geological history, and the origin and maintenance of its hostile atmosphere, to understand how Venus and Earth could have evolved so differently. EnVision will carry three instruments: the Venus Emission Mapper (VEM); the Subsurface Radar Sounder (SRS); and VenSAR, a world-leading European phased array synthetic aperture radar that is the subject of this article. VenSAR will obtain images at a range of spatial resolutions from 30 m regional coverage to 1 m images of selected areas; an improvement of two orders of magnitude on Magellan images; measure topography at 15 m resolution vertical and 60 m spatially from stereo and InSAR data; detect cm-scale change through differential InSAR, to characterise volcanic and tectonic activity, and estimate rates of weathering and surface alteration; and characterise of surface mechanical properties and weathering through multi-polar radar data. These data will be directly comparable with Earth Observation radar data, giving geoscientists unique access to an Earth-sized planet that has evolved on a radically different path to our own, offering new insights on the Earth-sized exoplanets across the galaxy