Novel use of stir bar sorptive extraction (SBSE) as a tool for isolation of oviposition site attractants for gravid Culex quinquefasciatus

Mosquitoes such as Culex quinquefasciatus Say (Diptera: Culicidae) are important vectors of organisms that cause disease in humans. Research into the development of effective standardized odour baits for blood-fed females (oviposition attractants), to enable entomological monitoring of vector populations, is hampered by complex protocols for extraction of physiologically active volatile chemicals from natural breeding site water samples, which have produced inconsistent results. Air entrainment and solvent extraction are technically demanding methods and are impractical for use in resource poor environments where mosquito-borne disease is most prevalent. This study reports the first use of a simple, robust extraction technique, stir bar sorptive extraction (SBSE), to extract behaviourally active small lipophilic molecules (SLMs) present in water samples collected from Cx. quinquefasciatus breeding sites in Tanzania. Extracts from a pit latrine and from a cess pool breeding site attracted more gravid Cx. quinquefasciatus in pair choice bioassays than control extracts, and coupled gas chromatography-electroantennography (GC-EAG) allowed tentative identification of 15 electrophysiologically active chemicals, including the known oviposition attractant, skatole (3-methylindole). Here, we have demonstrated, using simple pair choice bioassays in controlled laboratory conditions, that SBSE is effective for the extraction of behaviourally and electrophysiologically active semiochemicals from mosquito breeding site waters. Further research is required to confirm that SBSE is an appropriate technique for use in field surveys in the search for oviposition cues for Cx. quinquefasciatus

Zero mode quantization of multi-Skyrmions

A zero mode quantization of the minimal energy SU(2) Skyrmions for nucleon numbers four to nine and seventeen is described. This involves quantizing the rotational and isorotational modes of the configurations. For nucleon numbers four, six and eight the ground states obtained are in agreement with the observed nuclear states of Helium, Lithium and Beryllium. However, for nucleon numbers five, seven, nine and seventeen the spins obtained conflict with the observed isodoublet nuclear states.Comment: 37 pages, LaTeX, 4 figures. More careful treatment of double covers, reference adde

D-Dimensional Radiative Plasma: A Kinetic Approach

The covariant kinetic approach for the radiative plasma, a mixture of a relativistic moving gas plus radiation quanta (photons, neutrinos, or gravitons) is generalized to D spatial dimensions. The operational and physical meaning of Eckart's temperature is reexamined and the D-dimensional expressions for the transport coefficients (heat conduction, bulk and shear viscosity) are explicitly evaluated to first order in the mean free time of the radiation quanta. Weinberg's conclusion that the mixture behaves like a relativistic imperfect simple fluid (in Eckart's formulation) depends neither on the number of spatial dimensions nor on the details of the collisional term. The case of Thomson scaterring is studied in detail, and some consequences for higher dimensional cosmologies are also discussed.Comment: 28 pages, 1 figure, uses REVTE

Operator Analysis for the Higgs Potential and Cosmological Bound on the Higgs-Boson Mass

Using effective lagrangian, we examine the impacts of new physics on the electroweak baryogenesis. By analysing the high dimensional operators relevent to the Higgs potential we point out that the Higgs mass bound required by electroweak baryogenesis can be relaxed to the region allowed by experiments, provided that new physics appears at the TeV scale.Comment: 10 Pages, Tex, UMDHEP 93-07

Low temperature spin fluctuations in geometrically frustrated Yb3Ga5O12

In the garnet structure compound Yb3Ga5O12, the Yb3+ ions (ground state effective spin S' = 1/2) are situated on two interpenetrating corner sharing triangular sublattices such that frustrated magnetic interactions are possible. Previous specific heat measurements evidenced the development of short range magnetic correlations below 0.5K and a lambda-transition at 54mK (Filippi et al. J. Phys. C: Solid State Physics 13 (1980) 1277). From 170-Yb M"ossbauer spectroscopy measurements down to 36mK, we find there is no static magnetic order at temperatures below that of the lambda-transition. Below 0.3K, the fluctuation frequency of the short range correlated Yb3+ moments progressively slows down and as the temperature tends to 0, the frequency tends to a quasi-saturated value of 3 x 10^9 s^-1. We also examined the Yb3+ paramagnetic relaxation rates up to 300K using 172-Yb perturbed angular correlation measurements: they evidence phonon driven processes.Comment: 6 pages, 5 figure

Exact solution (by algebraic methods) of the lattice Schwinger model in the strong-coupling regime

Using the monomer--dimer representation of the lattice Schwinger model, with $N_f =1$ Wilson fermions in the strong--coupling regime ($\beta=0$), we evaluate its partition function, $Z$, exactly on finite lattices. By studying the zeroes of $Z(k)$ in the complex plane $(Re(k),Im(k))$ for a large number of small lattices, we find the zeroes closest to the real axis for infinite stripes in temporal direction and spatial extent $S=2$ and 3. We find evidence for the existence of a critical value for the hopping parameter in the thermodynamic limit $S\rightarrow \infty$ on the real axis at about $k_c \simeq 0.39$. By looking at the behaviour of quantities, such as the chiral condensate, the chiral susceptibility and the third derivative of $Z$ with respect to $1/2k$, close to the critical point $k_c$, we find some indications for a continuous phase transition.Comment: 22 pages (6 figures

Limits to Quantum Gravity Effects from Observations of TeV Flares in Active Galaxies

We have used data from the TeV gamma-ray flare associated with the active galaxy Markarian 421 observed on 15 May 1996 to place bounds on the possible energy-dependence of the speed of light in the context of an effective quantum gravitational energy scale. The possibility of an observable time dispersion in high energy radiation has recently received attention in the literature, with some suggestions that the relevant energy scale could be less than the Planck mass and perhaps as low as 10^16 GeV. The limits derived here indicate this energy scale to be in excess of 4x10^16 GeV at the 95% confidence level. To the best of our knowledge, this constitutes the first convincing limit on such phenomena in this energy regime.Comment: 6 pages, including 2 figure

Dynamical Viscosity of Nucleating Bubbles

We study the viscosity corrections to the growth rate of nucleating bubbles in a first order phase transition in scalar field theory. We obtain the non-equilibrium equation of motion of the coordinate that describes small departures from the critical bubble and extract the growth rate consistently in weak coupling and in the thin wall limit. Viscosity effects arise from the interaction of this coordinate with the stable quantum and thermal fluctuations around a critical bubble. In the case of 1+1 dimensions we provide an estimate for the growth rate that depends on the details of the free energy functional. In 3+1 dimensions we recognize robust features that are a direct consequence of the thin wall approximation and give the leading viscosity corrections.These are long-wavelength hydrodynamic fluctuations that describe surface waves, quasi-Goldstone modes which are related to ripples on interfaces in phase ordered Ising-like systems. We discuss the applicability of our results to describe the growth rate of hadron bubbles in a quark-hadron first order transition.Comment: 40 pages, 4 figures, revtex, minor changes, to be published in Phys. Rev.

Physio4FMD: protocol for a multicentre randomised controlled trial of specialist physiotherapy for functional motor disorder

Background Patients with functional motor disorder (FMD) experience persistent and disabling neurological symptoms such as weakness, tremor, dystonia and disordered gait. Physiotherapy is usually considered an important part of treatment; however, sufficiently-powered controlled studies are lacking. Here we present the protocol of a randomised controlled trial (RCT) that aims to evaluate the clinical and cost effectiveness of a specialist physiotherapy programme for FMD. Methods/design The trial is a pragmatic, multicentre, single blind parallel arm randomised controlled trial (RCT). 264 Adults with a clinically definite diagnosis of FMD will be recruited from neurology clinics and randomised to receive either the trial intervention (a specialist physiotherapy protocol) or treatment as usual control (referral to a community physiotherapy service suitable for people with neurological symptoms). Participants will be followed up at 6 and 12 months. The primary outcome is the Physical Function domain of the Short Form 36 questionnaire at 12 months. Secondary domains of measurement will include participant perception of change, mobility, health-related quality of life, health service utilisation, anxiety and depression. Health economic analysis will evaluate the cost impact of trial and control interventions from a health and social care perspective as well as societal perspective. Discussion This trial will be the first adequately-powered RCT of physical-based rehabilitation for FMD. Trial registration International Standard Randomised Controlled Trials Number ISRCTN56136713. Registered 27 March 2018