4 research outputs found
Classical strings in AdS4âĂCP3 with three angular momenta
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2011
- Field of study
In this paper, rotating strings in three directions of AdS4âĂCP3 geometry are studied; its divergent energy limit, and conserved
charges are also determined. An interpretation of these configurations as
either giant magnons or spiky strings are discussed
New insights into the genetic etiology of Alzheimerâs disease and related dementias
- Author
- A David Smith
- Aaltonen L.
- Aaltonen V.
- Aarno Palotie
- Aarsland D.
- Aavikko M.
- Abalos M. S.
- Abdelnour C.
- Abner E.
- Abraham R.
- Ad Adarmes-GĂłmez
- Adam Boxer
- Adam Ziemann
- Adams H.
- Adams P. M.
- Adarmes-GĂłmez A.
- Adarmes-GĂłmez A. D.
- Adriana Gamboa
- Adrienne L Cupples
- Adrienne Tin
- Aguilera N.
- Aguilera N.
- Aguirre A.
- Agustina Legaz
- Ahmad S.
- Aimee Pierce
- Aino Salminen
- Airi Jussila
- Aisha Khaleeq
- Aki Havulinna
- Akinyemi R. O.
- Al-Chalabi A.
- Alan B Stevens
- Alan Lerner
- AlarcĂłn-MartĂn E.
- Albert M. S.
- Alberto Benussi
- Albin R. L.
- Alcolea D.
- Aldo Saenz
- Alegret M.
- Alessandra Chesi
- Alessandro Vacca
- Alexander Teumer
- Alexis Brice
- Ali M.
- Alisa Manning
- Alison E Fohner
- Allan I Levey
- Allen M.
- Allende I. R.
- Alonso M. D.
- Alonso M. D.
- Alvarez I.
- Alvarez L.
- Alvin Thomas
- Alyssa Aguirre
- Amanda Cano
- Amanda Elliott
- Amanda G Smith
- Amanda J Myers
- Amer-Ferrer G.
- Amin N.
- Ammar Al-Chalabi
- Amouyel P.
- Amy Gerrish
- Amy Williams
- Ana MauleĂłn
- Ana Pancho
- Anastasia Shcherban
- Anastasiou A.
- Anastasiou C.
- Anders Malarstig
- Andrade V.
- Andrea Ganna
- Andreassen O. A.
- Andreoni S.
- Andrew J Saykin
- Andrew McQuillin
- Andrew N McDavid
- Andrew P Lieberman
- Andrew Peterson
- Andrey Loboda
- André Lacour
- Angela Hodges
- Aniket Mishra
- Ann C McKee
- Anna Anastasiou
- Anna Antonell
- Anna Gailhajenet
- Anna M Karydas
- Anna Podgornaia
- Anne Lehtonen
- Anne PitkÀranta
- Anne Remes
- Annette Fitzpatrick
- Annika Auranen
- Antequera M.
- Anthony Bayer
- Anthony Muslin
- Antikainen R.
- Antonell A.
- Antti Karlsson
- Antti PalomÀki
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- AntĂșnez C.
- Anu Jalanko
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- Aoibhinn Lynch
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- Xia T. -H.
- Xing Chen
- Xinli Hu
- Xiongwei Zhu
- Xu E.
- Xu F.
- Xuan Liu
- Yanbing Wang
- Yanek L.
- Yang Q.
- Yang Y.
- Yannakoulia M.
- Yaqub A.
- Yasaman Saba
- Yash Patel
- Yeunjoo E Song
- Yi Zhao
- Ying Wu
- Yoav Ben-Shlomo
- Yogen Patel
- Younkin S. G.
- Yu C. -E.
- Yu L.
- Yuanchao Zhang
- Yuk Yee Leung
- Yunfeng Huang
- Yunju Yang
- Zare H.
- Zdenka Pausova
- Zhang X.
- Zhang Y.
- Zhao Y.
- Zhao Y.
- Zhou W.
- Zhu C.
- Zhu X.
- Ziemann A.
- Zoia C. P.
- Zompo M. D.
- Zulaica M.
- Zulma Sevillano
- Ălvarez V.
- Ă sa Hedman
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2022
- Field of study
Characterization of the genetic landscape of Alzheimerâs disease (AD) and related dementias (ADD) provides a unique opportunity for a better understanding of the associated pathophysiological processes. We performed a two-stage genome-wide association study totaling 111,326 clinically diagnosed/âproxyâ AD cases and 677,663 controls. We found 75 risk loci, of which 42 were new at the time of analysis. Pathway enrichment analyses confirmed the involvement of amyloid/tau pathways and highlighted microglia implication. Gene prioritization in the new loci identified 31 genes that were suggestive of new genetically associated processes, including the tumor necrosis factor alpha pathway through the linear ubiquitin chain assembly complex. We also built a new genetic risk score associated with the risk of future AD/dementia or progression from mild cognitive impairment to AD/dementia. The improvement in prediction led to a 1.6- to 1.9-fold increase in AD risk from the lowest to the highest decile, in addition to effects of age and the APOE Δ4 allele
Search for intermediate-mass black hole binaries in the third observing run of Advanced LIGO and Advanced Virgo
- Author
- Abbott Rich
- Abbott Thomas D.
- Acernese Fausto
- Ackley Kendall
- Adams Carl
- Adhikari Naresh
- Adhikari Rana X.
- Adya Vaishali B.
- Affeldt Christoph
- Agarwal Deepali
- Agathos Michalis
- Agatsuma Kazuhiro
- Aggarwal Nancy
- Aguiar Odylio D.
- Aiello Lorenzo
- Ain Anirban
- Ajith P.
- Akutsu Tomotada
- Albanesi Simone
- Allocca Annalisa
- Altin Paul A.
- Amato Alex
- Anand Chandana
- Anand Shreya
- Ananyeva Alena
- Anderson Stuart B.
- Anderson Warren G.
- Ando Masaki
- Andrade Tomas
- Andres Nicolas
- AndriÄ Tomislav
- Angelova Svetoslava V.
- Ansoldi Stefano
- Antelis J.M.
- Antier Sarah
- Appert Stephen
- Arai Koji
- Arai Koya
- Arai Yuya
- Araki Sakae
- Araya Akito
- Araya Melody C.
- Areeda Joseph S.
- Arellano Fabian E. Peña
- Aritomi Naoki
- Arnaud Nicolas
- Aronson Scott M.
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- Asada Hideki
- Asali Yasmeen
- Ashton Gregory
- Aso Yoichi
- Assiduo Maria
- Aston Stuart M.
- Astone Pia
- Aubin Florian
- Austin Corey
- Babak Stanislav
- Badaracco Francesca
- Bader Maria K.M.
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- Bae Sangwook
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- Baer Anne M.
- Bagnasco Stefano
- Bai Yuntao
- Baiotti Luca
- Baird Jonathon
- Bajastani L.M. Daneshgaran
- Bajpai Rishabh
- Ball Matthew
- Ballardin Giulio
- Ballmer Stefan W.
- Balsamo Alexander
- Baltus Gregory
- Banagiri Sharan
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- Barbieri Claudio
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- Ding Binlei
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- GonzĂĄlez Gabriela
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- Gouaty Romain
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- Grace Benjamin
- Grado Aniello
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- Winkler Walter
- Wipf Christopher C.
- Wlodarczyk Tom
- Woan Graham
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- Wofford Jared K.
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- Wu David S.
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- Wysocki Daniel M.
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- Xu W-R.
- Yamada Tomohiro
- Yamamoto Hiro
- Yamamoto Kazuhiro
- Yamamoto Kohei
- Yamamoto Takahiro
- Yamashita Kanta
- Yamazaki Ryo
- Yang Fengwei W.
- Yang Le
- Yang Yang
- Yang Yi
- Yang Ziyan
- Yap M.J.
- Yeeles David W.
- Yelikar Anjali B.
- Ying Make
- Yokogawa Kazuya
- Yokoyama J.
- Yokozawa Takaaki
- Yoo Jooheon
- Yoshioka Toshiya
- Yu Hang
- Yu Haocun
- Yuzurihara Hirotaka
- ZadroĆŒny Adam
- Zanolin Michele
- Zeidler Simon
- Zelenova Tatiana
- Zendri J.-P.
- Zevin Michael
- Zhan Mingsheng
- Zhang Hong
- Zhang Jue
- Zhang Liyuan
- Zhang Teng
- Zhang Yanqi
- Zhao Chunnong
- Zhao Guoying
- Zhao Yue
- Zhao Yuhang
- Zhou Ruinan
- Zhou Zifan
- Zhu Xingjiang J.
- Zhu Z.-H.
- Zimmerman Aaron B.
- Zlochower Y.
- Zucker Michael E.
- Zweizig John
- Publication venue
- 'EDP Sciences'
- Publication date
- 01/01/2022
- Field of study
International audienceIntermediate-mass black holes (IMBHs) span the approximate mass range 100â105âMâ, between black holes (BHs) that formed by stellar collapse and the supermassive BHs at the centers of galaxies. Mergers of IMBH binaries are the most energetic gravitational-wave sources accessible by the terrestrial detector network. Searches of the first two observing runs of Advanced LIGO and Advanced Virgo did not yield any significant IMBH binary signals. In the third observing run (O3), the increased network sensitivity enabled the detection of GW190521, a signal consistent with a binary merger of mass âŒ150âMâ providing direct evidence of IMBH formation. Here, we report on a dedicated search of O3 data for further IMBH binary mergers, combining both modeled (matched filter) and model-independent search methods. We find some marginal candidates, but none are sufficiently significant to indicate detection of further IMBH mergers. We quantify the sensitivity of the individual search methods and of the combined search using a suite of IMBH binary signals obtained via numerical relativity, including the effects of spins misaligned with the binary orbital axis, and present the resulting upper limits on astrophysical merger rates. Our most stringent limit is for equal mass and aligned spin BH binary of total mass 200âMâ and effective aligned spin 0.8 at 0.056 Gpcâ3 yrâ1 (90% confidence), a factor of 3.5 more constraining than previous LIGO-Virgo limits. We also update the estimated rate of mergers similar to GW190521 to 0.08 Gpcâ3 yrâ1.Key words: gravitational waves / stars: black holes / black hole physicsCorresponding author: W. Del Pozzo, e-mail: [email protected]â Deceased, August 2020
New insights into the genetic etiology of Alzheimerâs disease and related dementias
- Author
- Aaltonen Lauri
- Aaltonen Vesa
- Aarsland Dag
- Aavikko Mervi
- Abalos Mariana Sanchez
- Abdelnour Carla
- Abner Erin
- Abraham Richard
- Adams Hieab
- Adams Perrie M.
- Adarmes-GĂłmez Ad
- Adarmes-GĂłmez Astrid D.
- Aguilera Nuria
- Aguilera Nuria
- Aguirre Alyssa
- Ahmad Shahzad
- Akinyemi Rufus O.
- Al-Chalabi Ammar
- AlarcĂłn-MartĂn Emilio
- Albert Marilyn S.
- Albin Roger L.
- Alcolea Daniel
- Alegret Montserrat
- Ali Muhammad
- Allen Mariet
- Allende Irene Rosas
- Alonso MarĂa Dolores
- Alonso MarĂa Dolores
- Alvarez Ignacio
- Alvarez Lisa
- Amer-Ferrer Guillermo
- Amin Najaf
- Amouyel Philippe
- Anastasiou Anna
- Anastasiou Costas
- Andrade Victor
- Andreassen Ole A.
- Andreoni Simona
- Antequera Martirio
- Antikainen Riitta
- Antonell Anna
- Anttonen Vuokko
- AntĂșnez Carmen
- Aparicio Hugo J.
- Apostolova Liana G.
- Appollonio Ildebrando
- Arcaro Marina
- Archetti Silvana
- Armstrong Nicola
- Armstrong Nicola J.
- Arnold Steven E.
- Arosio Beatrice
- Arvas Mikko
- Assogna Francesca
- Asthana Sanjay
- Athanasiu Lavinia
- Atwood Craig S.
- Auge Franck
- Auranen Annika
- Auvinen PĂ€ivi
- Awaisa Ghazal
- Ayres Gayle
- Bacha Juan Ignacio
- Bahadori Maryam
- Bahrami Shahram
- Bailly Henri
- Baldwin Clinton T.
- Banaj Nerisa
- Baquero Miquel
- Barber Robert C.
- Barnes Lisa L.
- Barral Sandra
- Barral Sandra
- Bass Nicholas J.
- Bass Nick
- Bastiani Patrizia
- Bayer Anthony
- Beach Thomas G.
- Becker James T.
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- Becker Tim
- Beecham Gary W.
- Beekly Duane
- Behrens Tim
- Beiser Alexa
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- Bellenguez CĂ©line
- Below Jennifer E.
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- Benchek Penelope
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- CarriĂłn-Claro Mario
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- Castaño Eduardo M.
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- Cervera-Carles Laura
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- Chang Diana
- Chapuis Julien
- Charbonnier Camille
- Chasman Daniel
- Chasse Scott
- Chatelain Clement
- Chauhan Ganesh
- Chen Chia-Yen
- Chen Hao
- Chen Hubert
- Chen Hung-Hsin
- Chen Xing
- Chene GeneviĂšve
- Chesi Alessandra
- Chesselet Marie-Francoise
- Chhibber Aparna
- Chillotti Caterina
- Chin Nathaniel A.
- Chipi Elena
- Choy David
- Chu Audrey
- Chui Helena C.
- Chung Jaeyoon
- Chung Jaeyoon
- Ciccone Simona
- Ciullo Valentina
- Claassen Jurgen A. H. R.
- Clarimon Jordi
- Clark Christopher
- Clarke Robert
- Close David
- Collinge John
- Comic Hata
- Conti Elisa
- Cores Valeria
- Corma-GĂłmez AnaĂŻs
- Costa Marcos R.
- Costantini Emanuele
- Cox Simon
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- Welsh-Bohmer Kathleen A.
- Whelan Christopher
- Whitehead Patrice L.
- Wichmann H-Erich
- Wigmore Eleonor
- Wijsman Ellen M.
- Wilcock Gordon
- Wilhelmsen Kirk C.
- Williams Amy
- Williams Benjamin
- Williams Dylan
- Williams Julie
- Williamson Jennifer
- Wilms Henrik
- Wiltfang Jens
- Windle Gill
- Wingo Thomas S.
- Wisniewski Thomas
- Wittfeld Katharina
- Woltjer Randall L.
- Wong Regis
- Woods Bob
- Woon Martin
- Wright Clinton B.
- Wu Chuang-Kuo
- Wu Ying
- Xia Tai-he
- Xu Ethan
- Xu Fanli
- Yanek Lisa
- Yang Qiong
- Yang Yunju
- Yannakoulia Mary
- Yaqub Amber
- Younkin Steven G.
- Yu Chang-En
- Yu Lei
- Zare Habil
- Zhang Xiaoling
- Zhang Yuanchao
- Zhao Yi
- Zhao Yi
- Zhou Wei
- Zhu Congcong
- Zhu Xiongwei
- Ziemann Adam
- Zoia Chiara Paola
- Zompo Maria Del
- Zulaica Miren
- Ălvarez Victoria
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/04/2022
- Field of study
Characterization of the genetic landscape of Alzheimerâs disease (AD) and related dementias (ADD) provides a unique opportunity for a better understanding of the associated pathophysiological processes. We performed a two-stage genome-wide association study totaling 111,326 clinically diagnosed/âproxyâ AD cases and 677,663 controls. We found 75 risk loci, of which 42 were new at the time of analysis. Pathway enrichment analyses confirmed the involvement of amyloid/tau pathways and highlighted microglia implication. Gene prioritization in the new loci identified 31 genes that were suggestive of new genetically associated processes, including the tumor necrosis factor alpha pathway through the linear ubiquitin chain assembly complex. We also built a new genetic risk score associated with the risk of future AD/dementia or progression from mild cognitive impairment to AD/dementia. The improvement in prediction led to a 1.6- to 1.9-fold increase in AD risk from the lowest to the highest decile, in addition to effects of age and the APOE Δ4 allele