Subtitulado y audiodescripción en páginas Web accesibles

Actas de: I Congreso de Accesibilidad a los Medios Audiovisuales para Personas con Discapacidad (AMADIS 06), celebrado en Madrid el 10 de julio de 2006

Diagnóstico de la gestión de acceso de usuarios en la Superintendencia de Serviciospublicos domiciliarios- norma ISO/IEC 27001:2013 numerales a.9.2.2 y a.9.3.1

El presente artículo pretende mostrar la importancia de la implementación de un diagnóstico de acceso seguro a las diferentes aplicaciones utilizadas en la Superservicios tomando como referencia la Norma ISO/IEC 27001:2013 Numerales A.9.2.2 y A.9.3.1, toda vez que realizando una buena implementación de seguridad generará confianza en el manejo de la información que se esta utilizando actualmente en la entidad tanto para usuarios internos como externos. Se quiere dar a conocer las falencias con las que se cuenta actualmente y las posibles recomendaciones que ayudarán a subsanarlas para lograr el manejo seguro y adecuado de la información.The present article intends to show the importance of the implementation of a diagnosis of safe access to the different applications used in the Superservicios taking as reference the ISO / IEC 27001: 2013 Standard Numerals A.9.2.2 and A.9.3.1, every time that performing a good security implementation will generate confidence in the management of the information that is currently being used in the entity for both internal and external users. It wants to make known the shortcomings with which it is currently available and thepossible recommendations that will help to remedy them to achieve the safe and adequate handling of the information

New communication technologies for inclusive education in and outside the classroom

This chapter explores new communication technologies and methods for avoiding accessibility and communication barriers in the educational environment. It is focused on providing real-time captions so students with hearing disabilities and foreign students, among others, could participate in an inclusive way in and outside the classroom. The inclusive proposals are based on the APEINTA educational project, which aims for accessible education for all. The research work proposes the use of mobile devices for teacher and students in order to provide more flexibility using the APEINTA real-time captioning service. This allows using this service from anywhere and at anytime, not only in the classroom.APEINTA is the result of collaboration among the Department of Computer Science and the Department of Electronic Technology, Universidad Carlos III, and the Spanish Centre of Captioning and Audiodescription (CESyA)1. This project was initially supported by the Ministry of Science and Innovation (2007 I+D projects - EA2008-0312) within the program of Studies and Analyses - Actions to Improve the Quality of Higher Education and the Activity of University Professors. Currently, the research presented in this chapter is being partially supported by France Telecom España S.A. and the MA2VICMR (S2009/TIC-1542), GEMMA (TSI-020302-2010-141) and SAGAS (TSI-020100-2010-184) research projects.Publicad

Dolor crònic i envelliment

En aquest treball analitzam les característiques neurofisiològiques i neuropsicològiques del dolor crònic enfront del dolor agut. En particular, partim de la definició que el dolor és un fenomen neurobiològic i psicològic en el qual diferents regions cerebrals processen aspectes com la intensitat, la durada i de com són de desagradables les sensacions corporals doloroses. Quant a la prevalença, hem demostrat que el dolor crònic afecta una gran proporció d’adults (especialment, la població gran) i provoca una pèrdua substancial de la qualitat de vida dels pacients. En aquest sentit, és rellevant destacar que el dolor crònic produeix canvis estructurals i funcionals importants en el sistema nerviós central, i alteracions cognitives, com la pèrdua de concentració, lentitud en el processament de la informació i memòria de treball. Aquests canvis són semblants als provocats per l’envelliment, per la qual cosa consideram que és peremptori desenvolupar intervencions terapèutiques per millorar la qualitat de vida dels pacients i que, al seu torn, redueixin l’impacte del dolor crònic en el sistema nerviós central.El presente trabajo pretende analizar las características neurofisiológicas y neuropsicológicas que posee el dolor crónico frente al dolor agudo. En particular, se parte de una definición del dolor como un fenómeno neurobiológico y psicológico en el que diferentes regiones cerebrales procesan aspectos como la intensidad, la duración o lo desagradable que resultan las sensaciones corporales dolorosas. En cuanto a la prevalencia, se ha demostrado que el dolor crónico afecta a una gran proporción de adultos y, en especial, a la población mayor, ocasionando una sustancial pérdida en la calidad de vida de los pacientes. En este sentido, resulta relevante destacar que el dolor crónico produce importantes cambios estructurales y funcionales en el sistema nervioso central, así como alteraciones cognitivas como pérdida de concentración, lentitud en el procesamiento de la información y memoria de trabajo. Estos cambios parecen ser similares a los que se producen como consecuencia del envejecimiento, por lo que se hace perentorio desarrollar intervenciones terapéuticas que mejoren la calidad de vida de los pacientes y que, a su vez, reduzcan el impacto que supone el dolor crónico en el sistema nervioso central

One-Pot Synthesis of Polycyclic Nucleosides with Unusual Molecular Skeletons

An R hydroxy pyrrolidine tricyclic nucleoside 3 and its spontaneous reaction with acetone is described. In this transformation highly functionalized polycyclic nucleosides with rather unusual molecular skeletons are formed in a complete regio-and stereoselective way. The reaction involves the formation of three new bonds, two of them novel carbon-carbon bonds, in a one-pot way. An enamine-iminium mechanism with participation of carbinolamine, iminium ion, and enamine intermediates is proposed as a plausible explanation for this transformation. The scope of the reaction is briefly studied concluding that the nature of the ketone (R1COR2) is critical for the initial attack of the NH to the carbonyl group.We thank Susana Ruiz for excellent technical assistance. The Spanish MEC/MCINN (project SAF 2006-12713-C02-01) and the Comunidad de Madrid (project BIPEDD-CM S-B10-0214-2006) are also acknowl- edged for financial support. The Spanish Consejo Superior de Investigaciones Cientı´ ficas is also acknowledged for a JAE-Doc contract to M.-C.B.Peer reviewe

Effectiveness of the Ponseti method in the treatment of clubfoot: a systematic review

Clubfoot is a common congenital deformity of the lower limbs. It should be treated as soon as possible so that its correction is more easily achieved. The objective of this systematic review was to assess the effectiveness of the Ponseti method in the treatment of clubfoot. A bibliographic search was carried out in different databases, including PubMed and SciELO. Filters such as full text and randomized controlled trial were selected to find those articles that best matched our search. Among the results, we selected the ones that interested us, and the rest were discarded, either because they did not meet the requirements for our work or because they were repeated. In total, we collected 19 articles, but after using the critical evaluation instrument CASPe, 7 of them were eliminated, leaving us with a total of 12 articles for our systematic review. After analyzing the results obtained in the selected articles, we concluded that the Ponseti method is effective in the treatment of clubfoot, presenting a high success rate.Partial funding for open access charge: Universidad de Málag

Rapid decrease in titer and breadth of neutralizing anti-HCV antibodies in HIV/HCV-coinfected patients who achieved SVR

The main targets for neutralizing anti-hepatitis C virus (HCV) antibodies (HCV-nAbs) are the E1 and E2 envelope glycoproteins. We have studied the characteristics of HCV-nAbs through a retrospective study involving 29 HIV/HCV-coinfected patients who achieved sustained virological response (SVR) with pegIFNα+ribavirin anti-HCV therapy. Plasma samples at baseline and week 24 after SVR were used to perform neutralization assays against fve JFH1-based HCV recombinant viruses coding for E1 and E2 from genotypes 1a (H77), 1b (J4), 2a (JFH1), 3a (S52) and 4a (ED43). At baseline, the majority of plasma samples neutralized 1a, 1b, 2a, and 4a, but not 3a, genotypes. Twenty-four weeks following SVR, most neutralizing titers declined substantially. Furthermore, titers against 3a and 2a were not detected in many patients. Plasma samples with high HCV-nAb titers neutralized all genotypes, and the highest titers at the starting point correlated with the highest titers at week 24 after SVR. In conclusion, high titers of broad-spectrum HCV-nAbs were detected in HIV/HCV-coinfected individuals, however, those titers declined soon after SVRThis study was supported by grants from Instituto de Salud Carlos III (ISCIII; grant numbers PI14/01094 and PI17/00657 to JB, PI17/00903 to JGG, PI14CIII/00011 and PI17CIII/00003 to SR) and Ministerio de Sanidad, Servicios Sociales e Igualdad (grant number EC11-241). Te study was also funded by the RD16CIII/0002/0002, RD16/0025/0018, and RD16/0025/0017 projects as part of the Plan Nacional R+D+I and co-funded by ISCIII- Subdirección General de Evaluación and the Fondo Europeo de Desarrollo Regional (FEDER