Are psychological belief built on the ideology of early christian fathers? [¿Se basan las creencias psicológicas en la ideología de los padres de la iglesia cristiana temprana?]

ABSTRACT The aims of the present study were to investigate the relationship between: a) Patristic ideology and mentalist and behaviorist beliefs, and b) the relationship between mentalist and behaviorist beliefs and cognitive, neuropsychological and interbehavioral beliefs. The beliefs were assessed through an instrument purposely built for this research. A sample composed of 284 university students of first-semester psychology (84 men and 200 women; mean ages M = 17.82 years, SD = 2.34, range 16-38 years) were enrolled. After performing structural equation modelling (SEM), results show that patristic ideology is not related to behaviorism (β = .09, p = .387), but it is related with mentalism (β = .26, p = .042), also the mentalism is related with cognitive beliefs (β = .72, p =.001) and neuropsychological beliefs (β = .87, p = .014), while behaviorism is related with interbehavioral beliefs (β = .42, p = .014). It was found that first-year psychology students show less acceptance of the early patristic ideology (M = 75.28), it is less successful than mentalism (M = 86.33). The conclusion is that mentalism, successor of Patristic ideology, continues to be related to cognitive and neuropsychological beliefs

In vivo expansion of a CD9+ decidual-like NK cell subset following autologous hematopoietic stem cell transplantation.

Autologous hematopoietic stem cell transplantation (autoHSCT) is a treatment option for hematological disorders and pediatric solid tumors. After an autoHSCT, natural killer (NK) cells are the first lymphocyte subset returning to normal levels. To uncover global changes during NK cell reconstitution after autoHSCT, we performed RNA-sequencing on NK cells before and after autoHSCT. Results showed profound changes in the gene expression profile of NK cells immediately after autoHSCT. Several biological processes including cell cycle, DNA replication and the mevalonate pathway were enriched. Significantly, we observed that following autoHSCT, NK cells acquired a decidual-like gene expression profile, including the expression of CD9. By using multiparametric flow cytometry, we confirmed the expansion of NK cells expressing CD9 immediately after autoHSCT, which exhibited higher granzyme B and perforin expression levels than CD9- NK cells. These results provide insights into the physiopathology of NK cells during their reconstitution after autoHSCT.Supported by the following grants: AECC-Spanish Association Against Cancer (PROYE16074- BORR) and Health Department, Basque Government (2021333006). GA-P is the recipient of a predoctoral contract funded by AECC-Spanish Association Against Cancer (PRDVZ21440ASTA). DP-A is a recipient of a fellowship from the AECC-Spanish Association Against Cancer (PPLAB212164POLA), AA-I and GA-P are recipient of a fellowship from the Jesús de Gangoiti Barrera Foundation (FJGB20/007, FJGB21/001 and FJBG21/005). IT is recipient of a predoctoral contract funded by the Department of Education, Basque Government (PRE_2021_2_0215). OZ is the recipient of a postdoctoral contract funded by ‘‘Instituto de Salud Carlos III-Contratos Sara Borrell 2017 (CD17/00128)’’ and the European Social Fund (ESF)-The ESF invests in your future. FB is an Ikerbasque Research Professor, Ikerbasque, Basque Foundation for Science.S

Variedad en paradigmas tecnológicos: innovación e invención del disco artificial

12 pages, 5 figures[EN]This article analyses the evolution of technological paradigms across the innovation and invention stages of the technological innovation process. The vehicle is the case of the evolution of artificial disc, a surgical implant employed in the treatment of degenerative disc disease, which is the first source of pain and disability in western countries. Designs of artificial disc can be classified in two technological paradigms, with different cost and outcome in their development. The results show that both, invention and innovation activities, increase their intensity in response to a growing demand. However, variety of inventive and innovative efforts behaves in different manner: while inventive efforts evolve in similar manner in both technological paradigms along the whole period, innovation efforts deal only with the development of less risky paradigm, although its functionality was suboptimal. Only when market signals point to a big increase in demand, innovation activities assume the development risks of the functionally optimal paradigm.[ES]Este artículo analiza la evolución de los paradigmas tecnológicos a lo largo de las fases de innovación e invención del proceso de innovación tecnológica. Para ello se estudia el caso de la evolución del disco artificial, un implante quirúrgico empleado en el tratamiento de la enfermedad degenerativa del disco, que constituye la primera causa de dolor e incapacidad en los países desarrollados. Los diseños de disco artificial pueden incluirse dentro de dos paradigmas tecnológicos, que implican distintos resultados y costes de desarrollo. Los resultados de este análisis muestran que tanto la actividad inventiva como la innovadora aumentaron su intensidad como respuesta al crecimiento de la demanda de este tipo de implantes. Sin embargo, la variedad de los esfuerzos inventivos e innovadores se comportó de manera distinta: mientras que los esfuerzos inventivos se dirigieron de manera similar a los dos paradigmas tecnológicos de disco artificial durante todo el periodo estudiado, los esfuerzos innovadores se ocuparon únicamente del paradigma que implicaba menor incertidumbre en su desarrollo, aunque su funcionalidad fuera subóptima. Sólo cuando recientemente las señales del mercado apuntaron a un gran crecimiento de la demanda, la actividad innovadora asumió los riesgos de desarrollo del paradigma funcionalmente óptimo.Peer reviewe

Loneliness, Depressive Mood and Cyberbullying Victimization in Adolescent Victims of Cyber Dating Violence

Currently, cyber dating violence (CDV) is a serious health problem among adolescents due to their frequent use of communication technologies in their romantic relationships including the use of these technologies to perpetrate dating violence. However, research on this topic is recent and more studies about victims’ psychosocial adjustment are needed. The objectives of this study were to analyze the prevalence of CDV victimization according to frequency (occasional and frequent) and type (cyber control and cyber-aggression) and to explore their relations with loneliness, depressive mood and cyberbullying victimization. A total of 604 adolescents (M age = 14.32, SD = 1.67) who had a dating relationship at the time or in the past 12 months, participated in this study. The results showed a higher prevalence for cyber-control than cyber-aggression victimization, and positive correlations of CDV victimization with depressive mood and cyberbullying victimization in boys and girls. Positive correlations with loneliness were also observed for girls. The average effect size of the aforementioned correlations was large for girls and medium for boys. Both boys and girls who were frequent victims of CDV also suffered more cyberbullying by peers than those who were never, and occasionally, cyber victimized by their partners. Girls who were frequent victims of CDV also reported higher scores for loneliness and depressive mood, with a small average effect size. All these results highlight close relations between cyberbullying and CDV in adolescents, being necessary to pay greater attention to possible experiences of poly-victimization, and a worse psychosocial adjustment in frequently victimized girls than boys. These findings may be useful for developing more effective intervention programs

Proceso de enseñanza-aprendizaje a través de la investigación y el uso de las TIC en la ESO

Con la introducción de las competencias básicas en el curriculum como parte esencial para la obtención de la titulación de la ESO, los profesores, autores de este trabajo se proponen valorar estas competencias a través de la investigación y el uso de las TIC. El objetivo es desarrollar las competencias básicas como método de aprendizaje a través de la investigación, el análisis crítico y el uso de las TIC. De esta forma se propicia que el alumno sea parte activa de su propio aprendizaje. Durante el primer trimestre de curso los alumnos llevaron un método tradicional para, de esta forma, poder comparar los resultados entre dos trimestres con alumnos y metodologías diferentes. La metodología se inicia con una presentación en PowerPoint, la explicación y la entrega del trabajo a realizar. Una vez realizado, se envía al profesor a través de correo electrónico o en Pen Drive. Después de este proceso se establece un debate con las conclusiones. Al final se presenta en formato ppt una exposición ante la clase. La evaluación se realiza a través de diferentes trabajos: búsqueda de información, interpretación de fuentes, gráficos, tablas de datos, etc. Se señalan como resultados, una mejora considerable, no solo en los resultados académicos, sino en la actitud hacia la asignatura.MurciaConsejería de Educación, Formación y Empleo. Servicio de Publicaciones y Estadística; Avda. de la Fama, 15 - 1ª planta; 30006 Murcia; Tel. +34968279685; Fax +34968279835; [email protected]

Las nuevas asociaciones de bibliotecarios de Castilla-La Mancha presentan para RUIDERAe el "Equipo B" de asociaciones de bibliotecarios de Castilla-La Mancha

Lo que hemos llamado el “Equipo B” de defensa bibliotecaria es un pequeño grupo de valientes profesionales que luchan por dignificar la profesión, mejorar cada día en su trabajo y dar visibilidad a la figura del bibliotecario. Todos los que formamos parte de este peculiar equipo somos bibliotecarios municipales, que llevamos ya unos cuantos lustros trabajando en bibliotecas y que, más allá de nuestras diferentes experiencias y nuestras propias y personales historias, somos unos apasionados de las bibliotecas, amamos nuestro trabajo y luchamos cada día por mejorar y dignificar nuestra profesió

X chromosome inactivation does not necessarily determine the severity of the phenotype in Rett syndrome patients

Rett syndrome (RTT) is a severe neurological disorder usually caused by mutations in the MECP2 gene. Since the MECP2 gene is located on the X chromosome, X chromosome inactivation (XCI) could play a role in the wide range of phenotypic variation of RTT patients; however, classical methylation-based protocols to evaluate XCI could not determine whether the preferentially inactivated X chromosome carried the mutant or the wild-type allele. Therefore, we developed an allele-specific methylation-based assay to evaluate methylation at the loci of several recurrent MECP2 mutations. We analyzed the XCI patterns in the blood of 174 RTT patients, but we did not find a clear correlation between XCI and the clinical presentation. We also compared XCI in blood and brain cortex samples of two patients and found differences between XCI patterns in these tissues. However, RTT mainly being a neurological disease complicates the establishment of a correlation between the XCI in blood and the clinical presentation of the patients. Furthermore, we analyzed MECP2 transcript levels and found differences from the expected levels according to XCI. Many factors other than XCI could affect the RTT phenotype, which in combination could influence the clinical presentation of RTT patients to a greater extent than slight variations in the XCI pattern