Exploring sustainable technical alternatives for Dutch dairy systems by integrating agro-economic modelling and public preferences assessment

Theoretical discussions on the joint consideration of multiple (economic, social and environmental) functions when assessing the sustainability of human actions are increasing. However few studies exist that integrate the social demand for multifunctional agriculture in the evaluation of the sustainability and the global welfare of society. This paper presents a methodology to answer to these questions: Which are the social demands for the multiple functions of agriculture and how can they be quantified?; Which are the feasible technical alternatives of land management to satisfy these demands?; What is the value of the land use alternatives according to social preferences and which alternatives optimally satisfy the social preferences?. The net utility of alternatives for society, and therefore their sustainability, will be measured as the sum of market and non-market net changes compared to the current situation. The proposed methodology combines economic valuation, integrated modelling, stakeholder analysis, and multi-criteria evaluation. In particular, different multi-criteria methods (QFD/ANP) and agro-economic modelling and optimizing tools (Landscape IMAGES) were used. The methodology will be fully illustrated through the case study of dairy farming landscapes in the Northern Friesian Woodlands, The Netherlands. Results show that for the case study it is possible to change current farming techniques and achieve more sustainable farming systems. The more sustainable alternatives are beneficial for farmers, obtaining higher gross margin, and for government, decreasing the current levels of subsidies in agri-environmental programs. Even current environmental restrictions can be slightly relaxed without compromising social demands to the analysed Dutch dairy farming systems.Land-use planning, public preferences, agro-economic models, Environmental Economics and Policy, Livestock Production/Industries,

Multifunctional Impacts of the Olive Farming Practices in Andalusia, Spain: An Analytic Network Approach

Olive agriculture represents one of the most important economic activities in the region of Andalusia, Spain. Additionally to its economic importance the multifunctional character of agriculture and its wide territorial presence entails that it has a high potential incidence in the environmental and social dimensions of the sustainable development of the region. Despite this importance, it is hypothesised and aimed to be contrasted that olive farmers are not implementing the agricultural practices optimal from an economic, environmental and social point of view. Contrasting this hypothesis entails to evaluate with a holistic and systemic approach the multiple impacts of the different technical alternatives to diverse agricultural practices. The use of the Analytic Network Process, a Multiple Criteria Decision Analysis technique, will be illustrated as a useful approach to deal with this kind of problems characterised by complexity, lack of information and risk. The study will focus on the average yield, climatic, environmental, etc., conditions of olive cultivation in Andalusia. The results seem to confirm the initial hypothesis when comparing the current situation with different scenarios of optimal technical alternatives. In particular the technical alternatives implemented nowadays they are far from being environmentally optimal. The multifunctional benefits and the technical costs of a change from the current situation to these optimal scenarios will be analysed.Olive farming practices, Multifunctionality, Analytic Network Process, Farm Management,

Knowledge Transfer on Digital Transformation: An Analysis of the Olive Landscape in Andalusia, Spain

The global economy, and agriculture, in particular, faces significant challenges and transformation pressures. A major challenge, and opportunity, is the transformation towards digital agriculture or agriculture 4.0, where knowledge transfer (KT) has an important role to play not only in ensuring that digital innovations reach end-users, but also that these innovations contribute to development in rural landscapes. This paper analyses the role of KT in the framework of digital transformation (DT) in the Andalusian olive landscape. Thus, from the perspective of knowledge-generating agents, the main knowledge emitting and receiving actors in the DT are identified by using Social Network Analysis techniques (SNA). Subsequently, the performance of the Technological Innovation System (TIS) in KT is evaluated by using the multi-criteria Analytic Hierarchy Process (AHP) method. The results suggest that the knowledge-generating agents, the knowledge transfer actors, and the scientific and dissemination media actors are the main knowledge emitters and highlight their role as cohesive actors of the social network. The main knowledge receivers are olive growers, cooperatives and non-cooperative groups. The results also indicate that the global performance of the TIS in the KT function is medium/low. Furthermore, in the KT sub-functions where the TIS in DT performs best is the quality of the transfer processes of DT, and where it performs worst is the sufficiency of spaces for KT

Certified Quality Systems and Good Practices in the Olive Farming Sector of Andalusia, Spain: Special Focus on Protected Designations of Origin

 Producing products of recognised and differentiated quality entails a competitive advantage for agro-food agents since consumers are increasingly demanding high-quality food and control in the production process as a whole in a transparent and verifiable manner. Certification of products and processes through the implementation of Certified Quality Systems (CQS) are voluntary and guarantees standards of quality beyond conventional and mandatory levels. CQS include European, national and regional regulations (such as Protected Designation of Origin – PDO, organic and integrated agriculture), ISO norms (such as 9000, 14001, 19011, and 22000), private protocols (GLOBALGAP, International Food Standard - IFS, Nature’s Choice, etc.), and specific regulations for particular products, among others...

Sustainability assessment of Territorial Short Food Supply Chains versus Large‐Scale Food Distribution: The case of Colombia and Spain

Assessing, designing and implementing more sustainable agri-food systems has become a high priority in scientific research and political agendas worldwide. The ongoing Russia-Ukraine conflict is highlighting the fragility of globalised food distribution systems, and there is a need to focus on alternatives. This manuscript assesses the sustainability of two largely opposing marketing alternatives, namely Territorial Short Food Supply Chains (TSFSCs) and Large-Scale Food Distribution (LSFD). Specifically, the cases of Bogota (Colombia) and Cordoba (Spain) are analysed, where the development of TSFSCs has very significant in recent years but which are of a very different nature. For this purpose, a multi-criteria model based on the Analytic Network Process (ANP) methodology has been developed, considering multiple economic, social and environmental criteria. The model has been evaluated by four interest groups. The results show that the social sub-criterion – distribution of added value – is highly prioritised, and that the TSFSCs are the most sustainable alternatives globally in both cities. In Bogota, direct sales (farmers market) are prioritised, whilst in Cordoba, chain with a local retail (specialised shops). The contribution of TSFSCs to ecosystem services, equity, territorial cohesion and the revitalisation of the economy is highlighted. By interest groups, civil society, academia and public administration prioritise TSFSCs. However, the market players in Cordoba prioritise LSFD with national product. The results indicate that TSFSCs have the potential to contribute to the consolidation of sustainable and resilient food systems.Funding for open access charge: Universidad de Málaga / CBUA

Social network of knowledge transfer in the digital transformation of the olive sector in Andalusia: Perspective of knowledge generation agents

[EN] The configuration of the social network of knowledge transfer in digital transformation (DT) in the Andalusian olive sector is analysed using Social Network Analysis techniques. The results indicate that universities and technology companies are the main knowledge emitting agents, while olive growers and cooperatives are the main receiving agents. The social network of DT has a high potential for the creation of social capital, however, most of the interactions established between actors are of very low intensity, which could lead to some actors being isolated from knowledge in DT.[ES] La configuración de la red social de transferencia de conocimiento en transformación digital (TD) del sector olivarero de Andalucía es analizada mediante el uso de técnicas de Análisis de Redes Sociales. Los resultados indican que las universidades y las empresas tecnológicas son los principales agentes emisores de conocimiento, mientras los olivareros y las cooperativas son los principales agentes receptores. La red tiene un alto potencial para la creación de capital social, aunque la mayoría de las interacciones son de intensidad muy débil, lo que podría conllevar a que algunos actores queden aislados del conocimiento en TD.Los autores agradecen el apoyo económico recibido del Instituto de Investigación y Formación Agraria y Pesquera (IFAPA) a través del proyecto de investigación “Transformación digital del sector oleícola en Andalucía: Análisis sistémico, estructural y funcional para impulsar su desarrollo (digitalOli)” (PR.AVA.AVA2019.009), cofinanciado al 80 % por el Fondo Europeo de Desarrollo Regional, dentro del Programa Operativo FEDER 2014-2020.Reina-Usuga, L.; Parra-López, C.; Carmona-Torres, C.; Sayadi, S. (2022). Red social de transferencia de conocimiento en la transformación digital del sector olivarero de Andalucía: perspectiva de los agentes de generación de conocimiento. Economía Agraria y Recursos Naturales - Agricultural and Resource Economics. 22(2):97-115. https://doi.org/10.7201/earn.2022.02.059711522

Extracellular Protease ADAMTS1 Is Required at Early Stages of Human Uveal Melanoma Development by Inducing Stemness and Endothelial-Like Features on Tumor Cells

We would like to thank members of JCRM’s laboratory and GENYO’s support units for helping with animal handling, technical assistance, and further discussion. The results published here are in part based upon data generated by the TCGA Research Network (www.cancer.gov/tcga). This manuscript will be part of CPT PhD Thesis belonging to the Doctorate Program on Biomedicine, UGR, Spain.Extracellular matrix remodeling within the tumor microenvironment has been recognized as a relevant dynamic framework during tumor growth. However, research on proteases that trigger this remodeling keeps revealing a wide range of actions including both pro- and anti-tumorigenic. The extracellular protease ADAMTS1 exemplifies this dual role. In this work, we first confirmed a positive correlation of ADAMTS1 with endothelial-like phenotype of human melanoma cells together with the finding of associated signatures, including key genes such as endothelial CDH5. Using a CRISPR-Cas9 approach, we observed that the inhibition of ADAMTS1 in an aggressive uveal melanoma model compromised its endothelial-like properties, and more importantly, caused a robust blockade on the progression of tumor xenografts. Although vasculature emerged affected in ADAMTS1-deficient tumors, the most relevant action implied the downregulation of endothelial CDH5 in tumor cells, in association with stemness markers. Indeed, melanoma sphere assays also revealed a deficient commitment to form spheres in the absence of ADAMTS1, directly correlating with stemness markers and, remarkably, also with CDH5. Finally, taking advantage of advanced bioinformatics tools and available public data of uveal melanomas, we disclosed new prognosis factors, including endothelial elements and ADAMTS proteases. Our findings support the key role of ADAMTS proteases for uveal melanoma development since earlier stages, modulating the complex crosstalk between extracellular matrix and the induction of stemness and endothelial-like features. To our knowledge, this is the first report that supports the development of therapeutic targets on the extracellular matrix to overcome uveal melanoma.This research was supported by Ministerio de Economía y Competitividad and Instituto de Salud Carlos III from Spain, co-financed by FEDER (PI16/00345 to JCRM) and from Consejería de Salud de la Junta de Andalucía (OH-0028-2018, PE-0225-2018)

SMOS REFLEX 2003: L-Band Emissivity Characterization of Vineyards

The goal of the Soil Moisture and Ocean Salinity mission over land is to infer surface soil moisture from multiangular L-band radiometric measurements. As the canopy affects the microwave emission of land, it is necessary to characterize different vegetation layers. This paper presents the Reference Pixel L-Band Experiment (REFLEX), carried out in June-July 2003 at the Vale/spl grave/ncia Anchor Station, Spain, to study the effects of grapevines on the soil emission and on the soil moisture retrieval. A wide range of soil moisture (SM), from saturated to completely dry soil, was measured with the Universitat Polite/spl grave/cnica de Catalunya's L-band Automatic Radiometer (LAURA). Concurrently with the radiometric measurements, the gravimetric soil moisture, temperature, and roughness were measured, and the vines were fully characterized. The opacity and albedo of the vineyard have been estimated and found to be independent on the polarization. The /spl tau/--/spl omega/ model has been used to retrieve the SM and the vegetation parameters, obtaining a good accuracy for incidence angles up to 55/spl deg/. Algorithms with a three-parameter optimization (SM, albedo albedo, and opacity) exhibit a better performance than those with one-parameter optimization (SM).Peer Reviewe

SMOS REFLEX 2003: L-band emissivity characterization of vineyards

The goal of the Soil Moisture and Ocean Salinity mission over land is to infer surface soil moisture from multiangular L-band radiometric measurements. As the canopy affects the microwave emission of land, it is necessary to characterize different vegetation layers. This paper presents the Reference Pixel L-Band Experiment (REFLEX), carried out in June-July 2003 at the Vale/spl grave/ncia Anchor Station, Spain, to study the effects of grapevines on the soil emission and on the soil moisture retrieval. A wide range of soil moisture (SM), from saturated to completely dry soil, was measured with the Universitat Polite/spl grave/cnica de Catalunya's L-band Automatic Radiometer (LAURA). Concurrently with the radiometric measurements, the gravimetric soil moisture, temperature, and roughness were measured, and the vines were fully characterized. The opacity and albedo of the vineyard have been estimated and found to be independent on the polarization. The /spl tau--//spl omega/ model has been used to retrieve the SM and the vegetation parameters, obtaining a good accuracy for incidence angles up to 55/spl deg/. Algorithms with a three-parameter optimization (SM, albedo albedo, and opacity) exhibit a better performance than those with one-parameter optimization (SM).Peer Reviewe

Short-Peptide Supramolecular Hydrogels for In Situ Growth of Metal–Organic Framework-Peptide Biocomposites

The development of bio-MOFs or MOF biocomposites through the combination of MOFs with biopolymers offers the possibility of expanding the potential applications of MOFs, making use of more environmentally benign processes and reagents and giving rise to a new generation of greener and more bio-oriented composite materials. Now, with the increasing use of MOFs for biotechnological applications, the development of new protocols and materials to obtain novel bio-MOFs compatible with biomedical or biotechnological uses is needed. Herein, and as a proof of concept, we have explored the possibility of using short-peptide supramolecular hydrogels as media to promote the growth of MOF particles, giving rise to a new family of bio-MOFs. Short-peptide supramolecular hydrogels are very versatile materials that have shown excellent in vitro and in vivo biomedical applications such as tissue engineering and drug delivery vehicles, among others. These peptides self-assemble by noncovalent interactions, and, as such, these hydrogels are easily reversible, being more biocompatible and biodegradable. These peptides can self-assemble by a multitude of stimuli, such as changes in pH, temperature, solvent, adding salts, enzymatic activity, and so forth. In this work, we have taken advantage of this ability to promote peptide self-assembly with some of the components required to form MOF particles, giving rise to more homogeneous and well-integrated composite materials. Hydrogel formation has been triggered using Zn2+ salts, required to form ZIF-8, and formic acid, required to form MOF-808. Two different protocols for the in situ MOF growth have been developed. Finally, the MOF-808 composite hydrogel has been tested for the decontamination of water polluted with phosphate ions as well as for the catalytic degradation of toxic organophosphate methyl paraoxon in an unbuffered solution.Grants PID2020-118498GB-I00PID2020-113608RB-I00MCIN/AEI/10.13039/ 501100011033,Projects P18-FR-3533 and A-FQM-340-UGR20 by FEDER/Junta de Andaluci ́ a-Consejería de Transformación Económica, Industria, Conocimiento y Universidades (Spain)PPJIA2021.20 by Universidad de GranadaMarie Skłodowska-Curie Individual Fellowship (H2020-MSCA-IF-2019-EF-ST-888972-PSustMOF)European Union H2020 programme and EU FEDERGrant PRE2018-083773MCIN/ AEI/10.13039/501100011033ESF Investing in your future”, Spain