2,218 research outputs found

    Distal subgaleal-peritoneal shunt migration into the abdominal wall with subsequent formation of a pre-peritoneal pseudocyst: a rare complication.

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    Distal ventriculo-peritoneal shunt migration and extra-peritoneal CSF pseudocyst formation are unusual complications of shunt placement. We present a 65-year-old-female who received a subgaleal-peritoneal shunt to decompress a post-surgical subgaleal fluid collection. Eight weeks later, shunt series showed tight coiling of the distal catheter, and operative exploration found the distal shunt tip to have migrated superficial to the rectus sheath, where it had become encapsulated in a pre-peritoneal CSF pseudocyst. Migration of the distal catheter into the abdominal wall was likely due to local inflammation of the inner surface of the abdomen, with pressure from intestinal peristaltic movements and intra-abdominal pressure, and continued inflammation at the distal catheter tip may have caused formation of a pre-peritoneal CSF pseudocystic dilatation. To date, this is the first reported case of distal shunt migration into the abdominal wall with subsequent formation of an extra-peritoneal pseudocyst and represents a rare event in the surgical management of peritoneal shunts

    Game-theoretic analysis of pay-as-bid mechanisms

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    Enterprises are facing a challenging dilemma. In order to be able to accommodate peak loads on their IT systems, they must maintain large computing clusters, which lie idle most of the time. At the same time, IT departments are under constant pressure to cut down on hard- and software expenses. Grid technology offers a promising way out of this dilemma by allowing the dynamic sharing both within enterprises as well as across organizational boundaries. This sharing approach, however, requires proper economic incentives. This paper is concerned with the determination of dynamic market-based prices. Due to their simplicity, so-called pay-as-bid mechanisms have become popular. This paper is novel as we provide an in-depth analysis of two such pay-as-bid mechanisms – Proportional Share and a discriminatory pay-as-bid mechanism – for the case of three users, thus extending previous work by Sanghavi and Hajek (2004) and Stößer et al. (2008). This analysis is important as we show that the nice results for two users cannot be retained once three or more users are present. Even worse, we show that these results can even be reversed if we move to games with more than two players

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    Perioperative Care for Kidney Transplant Recipients

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    Transplantation carries significant mortality benefit compared to dialysis in end-stage kidney disease. Increased perioperative risk, however, results in a higher mortality in the first 3 months post-transplantation compared to remaining on haemodialysis. Consequently, optimal perioperative management is essential. Patients presenting for kidney transplantation require rapid assessment and preparation for theatre to minimise ischaemic times and improve mortality and graft outcomes. This task is often complicated by the presence of multiple medical comorbidities. Furthermore, early complications of hypotension, delayed graft function, renovascular and ureteric surgical complications and rejection render the perioperative phase of transplant challenging for the recipient and for the transplant team. In this chapter, we outline current practices in the assessment and management of kidney transplant recipients during the perioperative period, particularly focusing on their clinical application and the evidence underpinning them

    Planning syllabus through professional partnership.

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    In most institutions of higher education, English for Specific Purposes (ESP) has evolved into a professional field that has multiple perspectives (Johns, 2002), multi-disciplinary approaches (Dudley-Evans & St John, 1998), and sound research-based pedagogy (Belcher & Braine, 1995). pecifically, ESP practitioners take into account the needs of clients to develop academic courses through professional partnerships with the various stakeholders (Dudley-Evans & St John, 1998). The authors would like to share one such experience at Nanyang Technological University (Singapore) in designing, delivering and evaluating a writing course using the portfolio approach, which was specially tailored to the needs of its science students in the School of Physical and Mathematical Sciences. The presentation will cover the course of events chronologically from the preliminary discussions between the subject specialists and language experts to negotiate course objectives, the development of the syllabus based on these mutually-agreed goals, the delivery and fine-tuning of the course to the final stage of evaluating the curriculum taking into consideration feedback from tutors and students. The focus will be on the key developments and resulting decisions on matters such as content, approach, structure and assessment of the writing course that lead to a win-win outcome through a collegial partnership between the subject specialists and language experts

    Familial sleep and autism spectrum disorder: a pilot actigraphy study of sleep quality, quality of life and psychological distress

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    Sleep problems are common among children with autism spectrum disorder (ASD) and can have a negative impact on the child's behaviour and daytime functioning. The current pilot study examined objective measurements of child and parent sleep as factors associated with the stress, anxiety, depressive symptoms, social support and quality of life of parents of children with ASD. Participants were nine children with ASD and their parents (nine mothers and three fathers). Participants wore an actigraph for 7 consecutive days and nights. Measures of sleep habits and quality were used to ascertain child and parent sleep. Measures of parenting stress, anxiety, depressive symptoms, quality of life and social support were collated. Results indicated the emergence of high parental stress, anxiety and depressive symptoms. Significant correlations were observed between parent depressive symptoms, and both subjective sleep quality and child sleep disruptions. The present study found that parental well-being is affected by child sleep problems.peer-reviewe

    Mouse models of preterm birth: Suggested assessment and reporting guidelines

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    Preterm birth affects approximately 1 out of every 10 births in the United States, leading to high rates of mortality and long-term negative health consequences. To investigate the mechanisms leading to preterm birth so as to develop prevention strategies, researchers have developed numerous mouse models of preterm birth. However, the lack of standard definitions for preterm birth in mice limits our field\u27s ability to compare models and make inferences about preterm birth in humans. In this review, we discuss numerous mouse preterm birth models, propose guidelines for experiments and reporting, and suggest markers that can be used to assess whether pups are premature or mature. We argue that adoption of these recommendations will enhance the utility of mice as models for preterm birth
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