PROBLEMAS DE REEMPLAZO: ENFOQUES DE INVESTIGACIÓN DE OPERACIONES Y ECONOMÍA

Se realiza el análisis de los enfoques de Investigación de Operaciones y Económico para la generación de alternativas que permitan tomar la política más adecuada de reemplazo de bienes, utilizados en los procesos de producción. Se presenta una clasificación de modelos de reemplazo usados por la Investigación de Operaciones los que buscan directamente optimizar variables de costo e indirectamente optimizar la productividad. Se presenta y analiza el enfoque y modelos usados por la Economía para el análisis de reemplazo

FORECAST AND ANALYSIS OF THE NINO PHENOMENON OVER THE NORTH OF PERU

El Niño is one of the phenomena ocean atmospheric that with major frequency impacts over the north region of Peru, which is characterized for intensity rains in the north zone of Peru, causing enormous economic losses and damages in the agriculture, road infrastructure, fisheries, in the education sector, health sector between others. Based on the historical monthly information of the sea surface temperature of the zones Tumbes, Paita and Chicama and using the tools stochastic of prediction as like The Markov's chains, in this research one tries to predict the possible appearance of these events front the Peruvian sea in agreement to different levels of intensity. Using the series of monthly information from beginning until the year 2007 and on the basis of a matrix of transition of Markov's chain, there becomes an attempt of forecast of the appearance of an event El Niño for 2009 of agreement to scales of intensity for the zones of Tumbes, Paita and Chicama in a transitional probabilities matrix

Human Leptospirosis Caused by a New, Antigenically Unique Leptospira Associated with a Rattus Species Reservoir in the Peruvian Amazon

As part of a prospective study of leptospirosis and biodiversity of Leptospira in the Peruvian Amazon, a new Leptospira species was isolated from humans with acute febrile illness. Field trapping identified this leptospire in peridomestic rats (Rattus norvegicus, six isolates; R. rattus, two isolates) obtained in urban, peri-urban, and rural areas of the Iquitos region. Novelty of this species was proven by serological typing, 16S ribosomal RNA gene sequencing, pulsed-field gel electrophoresis, and DNA-DNA hybridization analysis. We have named this species “Leptospira licerasiae” serovar Varillal, and have determined that it is phylogenetically related to, but genetically distinct from, other intermediate Leptospira such as L. fainei and L. inadai. The type strain is serovar Varillal strain VAR 010T, which has been deposited into internationally accessible culture collections. By microscopic agglutination test, “Leptospira licerasiae” serovar Varillal was antigenically distinct from all known serogroups of Leptospira except for low level cross-reaction with rabbit anti–L. fainei serovar Hurstbridge at a titer of 1∶100. LipL32, although not detectable by PCR, was detectable in “Leptospira licerasiae” serovar Varillal by both Southern blot hybridization and Western immunoblot, although on immunoblot, the predicted protein was significantly smaller (27 kDa) than that of L. interrogans and L. kirschneri (32 kDa). Isolation was rare from humans (2/45 Leptospira isolates from 881 febrile patients sampled), but high titers of MAT antibodies against “Leptospira licerasiae” serovar Varillal were common (30%) among patients fulfilling serological criteria for acute leptospirosis in the Iquitos region, and uncommon (7%) elsewhere in Peru. This new leptospiral species reflects Amazonian biodiversity and has evolved to become an important cause of leptospirosis in the Peruvian Amazon

Automedicación y efectos secundarios del fármaco Claritromicina en personas que acuden a la botica Kristel Farma. Huaycan Ate Lima 2020

Objetivo: Comprobar en qué medida la automedicación se asocia a los efectos secundarios del fármaco Claritromicina en personas que compran en la botica Kristel farma Huaycán Ate Lima Julio 2020. Metodología: La investigación que presentamos a continuación es de tipo no experimental y de nivel correlacional y la metodología observacional de corte transversal. La muestra fue 120 personas los cuales realizan sus compras en la Botica Kristel farma Huaycán Ate (adultos y ancianos). Respecto a la técnica para recolección de datos se utilizó la encuesta y se procesó los datos mediante software SPSS. Resultados: Se evidencia que 50% de pacientes habían mostrado un síntoma horas posteriores a haber ingerido claritromicina a veces se automedicaron, pero el 18.2% de personas que habían presentado un síntoma horas posteriores a haber ingerido claritromicina siempre se automedicaron y el 31.8% de las personas que presentaron un síntoma horas después de ingerir claritromicina nunca se automedicaron. Además, el 16.9% de personas quienes no presentaron ningún síntoma horas posteriores de haber consumido claritromicina nunca se automedicaron, el 42.4% de personas que no habían presentado ningún síntoma horas después de ingerir claritromicina siempre se automedicaron y el 40.7% de personas que no habían presentado ningún síntoma horas posteriores a ingerir claritromicina a veces se automedicaron Conclusión: La frecuencia de automedicación no presenta asociación con efectos secundarios asociados al fármaco claritromicina en personas que aciden a la Botica Kristel farma Huaycán Ate Lima julio 202

Human Leptospirosis caused by a new antigenically unique Leptospira associated with a Rattus species reservoir in the Peruvian Amazon

As part of a prospective study of leptospirosis and biodiversity of Leptospira in the Peruvian Amazon, a new Leptospira species was isolated from humans with acute febrile illness. Field trapping identified this leptospire in peridomestic rats (Rattus norvegicus, six isolates; R. rattus, two isolates) obtained in urban, peri-urban, and rural areas of the Iquitos region. Novelty of this species was proven by serological typing, 16S ribosomal RNA gene sequencing, pulsed-field gel electrophoresis, and DNA-DNA hybridization analysis. We have named this species “Leptospira licerasiae” serovar Varillal, and have determined that it is phylogenetically related to, but genetically distinct from, other intermediate Leptospira such as L. fainei and L. inadai. The type strain is serovar Varillal strain VAR 010T, which has been deposited into internationally accessible culture collections. By microscopic agglutination test, “Leptospira licerasiae” serovar Varillal was antigenically distinct from all known serogroups of Leptospira except for low level cross-reaction with rabbit anti–L. fainei serovar Hurstbridge at a titer of 1∶100. LipL32, although not detectable by PCR, was detectable in “Leptospira licerasiae” serovar Varillal by both Southern blot hybridization and Western immunoblot, although on immunoblot, the predicted protein was significantly smaller (27 kDa) than that of L. interrogans and L. kirschneri (32 kDa). Isolation was rare from humans (2/45 Leptospira isolates from 881 febrile patients sampled), but high titers of MAT antibodies against “Leptospira licerasiae” serovar Varillal were common (30%) among patients fulfilling serological criteria for acute leptospirosis in the Iquitos region, and uncommon (7%) elsewhere in Peru. This new leptospiral species reflects Amazonian biodiversity and has evolved to become an important cause of leptospirosis in the Peruvian Amazon.Fil: Matthias, M.. University of California at San Diego; Estados UnidosFil: Ricaldi, Jessica. N.. University of California at San Diego; Estados UnidosFil: Cespedes, Manuel. National Institute of Health; PerúFil: Díaz, María Mónica. Universidad Nacional de Tucumán. Facultad de Ciencias Naturales e Instituto Miguel Lillo. Programa de Investigación de Biodiversidad Argentina; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán; ArgentinaFil: Galloway, R. L.. Disease Control and Prevention, Atlanta; Estados UnidosFil: Saito Mayuko. Asociacion Benefica PRISMA; PerúFil: Steigerwalt, Arnold G.. Centers for Disease Control and Prevention, Atlanta; Estados UnidosFil: Patra, Kallash P.. University of California at San Diego; Estados UnidosFil: Vidal Ore, Carlos. Ministry of Health; PerúFil: Gotuzzo, Eduardo. Universidad Peruana Cayetano Heredia; PerúFil: Gilman, Robert H.. Johns Hopkins Bloomberg School of Public Health; Estados UnidosFil: Levett, Paul N.. Saskatchewan Disease Control Laboratory; CanadáFil: Vinetz, Joshep M.. University of California at San Diego; Estados Unido

Fundamentos Biológicos - CD33 - 202101

Fundamentos biológicos es una asignatura que conduce al análisis de la estructura y el funcionamiento de la célula. Este curso utiliza la metodología activa en sesiones de discusión, prácticas de laboratorio, sesiones de discusión en pequeños grupos y actividades en línea. Este curso está dirigido a estudiantes de Ciencias de la actividad Física y el deporte; Terapia Física y Odontología. Tiene como propósito que los estudiantes adquieran el conocimiento y desarrollen la comprensión de los fundamentos biológicos sobre los que se fundamenta la práctica profesional de salud