20 research outputs found
The Bartle Bilinear Integration and Carleman Operators
AbstractSome characterizations of integrable functions in the bilinear sense of Bartle with respect to the injective tensor product are obtained. As a consequence it is shown that the kernels of Carleman compact operators coincide with these Bartle integrable functions. This result is applied to prove that every Carleman L-weak-compact operator is compact. An example showing the different behavior of the integrability with respect to the projective tensor product is given. A general Fubini theorem in this setting is shown
Source analysis of polyspike and wave complexes in juvenile myoclonic epilepsy
AbstractWe applied dipole modeling and brain distributed source analysis to find current sources comprising spikes and slow waves of polyspike and wave complexes (PSWC) in patients with juvenile myoclonic epilepsy (JME). The dipoles were localized in frontal, parietal and temporal lobes. The frontal dipoles were clustered in the frontal medial gyrus and fronto-orbital region. A midsagittal frontal current source was observed using brain distributed source analysis in all patients. When the slow wave was analyzed, multiple sources in different cortical regions were detected using dipole modeling and brain distributed analysis. These results show pre-frontal medial current sources corresponding to spikes and many diffuse sources in cortical regions corresponding to wave components of PSWC in patients with JME
Antimicrobial Susceptibilities of 1,730 Haemophilus influenzae Respiratory Tract Isolates in Spain in 1998-1999
A β-lactamase prevalence of 23% was found among 1,730 Haemophilus influenzae isolates. Ampicillin susceptibility was 70%, and 12% of β-lactamase-negative strains presented diminished susceptibility to ampicillin (BLNAR phenotype). Susceptibility of 90% was found for cefaclor and clarithromycin, whereas it was nearly 100% for cefotaxime, cefixime, azithromycin, and cefuroxime. Ciprofloxacin-resistant (0.1%) and β-lactamase-positive amoxicillin/clavulanate-resistant (BLPACR) phenotypes (0.1%) are anecdotal so far
Parallel-stranded hairpins containing 8-aminopurines. novel efficient probes for triple-helix formation
Purification and characterization of rat hippocampal CA3-dendritic spines associated with mossy fiber terminals
Urolithins Are the Main Urinary Microbial-Derived Phenolic Metabolites Discriminating a Moderate Consumption of Nuts in Free-Living Subjects with Diagnosed Metabolic Syndrome
Walnuts (Juglans regia L.), hazelnuts
(Corylus avellana L.), and almonds
(Prunus dulcis Mill.) are rich sources
of ellagitannins and proanthocyanidins. Gut microbiota plays a crucial
role in modulating the bioavailability of these high molecular weight
polyphenols. However, to date there are no studies evaluating the
capacity to produce nut phenolic metabolites in subjects with metabolic
syndrome (MetS), a pathology associated with an altered gut bacterial
diversity. This study applied a LC-MS targeted approach to analyze
the urinary excretion of nut phenolic metabolites in MetS subjects
following 12 weeks of nut consumption, compared to sex- and age-matched
individuals given a nut-free control diet. Metabolites were targeted
in both hydrolyzed and nonhydrolyzed urine by LC-PDA-QqQ-MS/MS analysis,
and identification of metabolites lacking available standards was
confirmed by LC-ESI-ITD-FT-MS. Ellagitannin-derived urolithins A and
B significantly increased after the nut-enriched-diet, urolithins
C and D were also detected, and a complex combination of urolithin-conjugated
forms was observed in nonhydrolyzed urine, confirming an extensive
phase II metabolism after absorption. In contrast, no significant
increases in proanthocyanidin microbial metabolites were observed
in urine following nut consumption. Because the intestinal microbiota
of the subjects in this study could catabolize ellagitannins into
a wide range of urolithins, further research is strongly warranted
on the in vivo potential of these microbial metabolites in reducing
cardiometabolic risk