407 research outputs found
An Efficient FPGA-Based Frequency Shifter for LTE/LTE-A Systems
The Physical Random Access Channel plays an important role in LTE and LTE-A systems. Through this channel, the user equipment aligns its uplink transmissions to the eNodeB’s uplink and gains access to the network. One of the initial operations executed by the receiver at eNodeB side is the translation of the channel’s signal back to base-band. This operation is a necessary step for preamble detection and can be executed through a time-domain frequency-shift operation. Therefore, in this paper, we present the hardware architecture and design details of an optimised and configurable FPGA-based time-domain frequency shifter. The proposed architecture is based on a customised Numerically Controlled Oscillator that is employed for creating complex exponential samples using only plain logical resources. The main advantage of the proposed architecture is that it completely removes the necessity of saving in memory a huge number of long complex exponentials by making use of a Look-Up Table and exploiting the quarter-wave symmetry of the basis waveform. The results demonstrate that the proposed architecture provides high Spurious Free Dynamic Range signals employing only a minimal number of FPGA resources. Additionally, the proposed architecture presents spur-suppression ranging from 62.13 to 153.58 dB without employing any correction
A rat model of restrictive bariatric surgery with gastric banding
Obes Surg. 2006 Jan;16(1):48-51.
A rat model of restrictive bariatric surgery with gastric banding.
Monteiro MP, Monteiro JD, Aguas AP, Cardoso MH.
Department of Anatomy of ICBAS (Abel Salazar Institute for the Biomedical Sciences), and Division of Endocrinology of Santo Antonio General Hospital, University of Porto, Porto, Portugal. [email protected]
Abstract
BACKGROUND: Gastric banding is a well established weight reduction operation that is effective in the treatment of severe obesity. Its metabolic and endocrine mechanisms of action, however, remain unclear. The aim of this study was to establish a rat model of gastric banding that would replicate the procedure performed in human obese patients.
METHODS: Male Wistar rats were submitted either to gastric banding (n=5) or sham gastric banding (n=4), and were followed for 21 days. Detailed description on how to perform gastric banding in rats are herein described.
RESULTS: The Wistar rats submitted to gastric banding showed a decrease in weight gain and food intake when compared to sham-operated rats. The cumulative weight gain during the 21 days after the surgical procedure was 143+/-2.58 g for the gastric banded rats and 162+/-2.48 g for the sham-operated animals (P=0.001). The cumulative food intake was 329+/-0.53 g for the gastric banded rats and 380+/-15.22 g for the sham-operated animals, also statistically significant (P=0.025).
CONCLUSION: A rat model to study gastric banding is described. This model can now be used for experimental investigation of biochemical and molecular mechanisms of weight loss resulting from this type of surgery.
PMID: 16417758 [PubMed - indexed for MEDLINE
Rats submitted to gastric banding are leaner and show distinctive feeding patterns
Obes Surg. 2006 May;16(5):597-602.
Rats submitted to gastric banding are leaner and show distinctive feeding patterns.
Monteiro MP, Monteiro JD, Aguas AP, Cardoso MH.
Department of Anatomy, Unit for Multidisciplinary Biomedical Research, Abel Salazar Institute for the Biomedical Sciences, University of Porto, 4099-003 Porto, Portugal. [email protected]
Abstract
BACKGROUND: Bariatric surgery is expanding to meet the global epidemic of morbid obesity, because this surgery is successful in achieving sustained weight loss. After having recently established a rat model of gastric banding, our aim now was to investigate the relative fat mass content and the feeding patterns of gastric banded rats.
METHODS: Two groups of Wistar rats, submitted either to gastric banding or to sham surgery, were followed-up for 26 days regarding weight, daily food intake and feeding patterns both under resting conditions and when refed after fasting. Weight of the epididymal fat pad was used as a measure to evaluate changes in white adipose tissue in the rats.
RESULTS: 10 days after surgery and thereafter, rats submitted to gastric banding showed the same daily food intake that was observed in sham-operated rats. Nevertheless, gastric banded rats kept lower body weights and were leaner than controls. These differences were associated with distinctive feeding patterns, both under resting conditions and when refed after fasting, suggesting that gastric banded rats present a significant increase in feeding frequency when compared with controls.
CONCLUSION: This data is the first experimental evidence that an increase in feeding frequency is associated with weight loss after gastric banding, even if there is no decrease in total energy intake. Thus, medical advice on the advantages of fractionating daily caloric intake into multiple meals is further supported by the herein new information obtained in an animal model of gastric banding
PS-HEMA latex fractionation by sedimentation and colloidal crystallization
A poly(styrene-co-hydroxyethylmethacrylate) latex underwent sedimentation under gravity followed by an spontaneous and extensive colloidal crystallization. It was then fractionated in three visually distinguishable layers. Latex aliquots layers were sampled at different heigths and the particles were characterized by PCS, microelectrophoresis, infrared spectra and analytical electron microscopy. The major fraction was opalescent and contained the colloidal crystals settled in the bottom of the liquid. Two other latex fractions were obtained, which differed in their chemical compositions, particle sizes and topochemical features from the self-arraying particles. Macrocrystallization of the fractionated latex yielded high quality crystals with a low frequency of defects, which confirms that particle chemical homogeneity is an important factor for particle self-arraying.Látex de poli(estireno-co-hidroxiacrilato de metila) separa-se em três camadas visualmente distinguÃveis, das quais a inferior é opalescente e contém cristais coloidais. AlÃquotas do látex foram coletadas em diferentes alturas, e as partÃculas foram caracterizadas, por espalhamento de luz dinâmico, microeletroforese, IV e microscopia eletrônica analÃtica. A fração inferior contém a maior parte do polÃmero, sendo formada por partÃculas de dimensões e composição quÃmica uniformes. As partÃculas coletadas das duas outras frações são diferentes das que formam os cristais coloidais, em praticamente todos os aspectos. A secagem da fração opalescente produz macrocristais de alta qualidade, com baixa frequência de defeitos, mostrando que a homogeneidade quÃmica das partÃculas é um fator importante, na sua auto-organização.497504Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvimento CientÃfico e Tecnológico (CNPq)Coordenação de Aperfeiçoamento de Pessoal de NÃvel Superior (CAPES
Gravity Waves, Turbulence and Rotors in the Lee of Mountains
This thesis has focussed on analysing the influence of a temperature inversion in the upstream profile of flow over ridges.
Under northerly conditions, a temperature inversion is commonly observed in the Falkland islands radiosonde launches and severe turbulence is usually coupled with it. The turbulence is presumed to be linked to gravity wave activity and is associated with high temporal and spatial variability in wind speed and direction. Recirculation zones are commonly found under the crest of the waves and their three dimensional structure pose a significant hazard to air traffic. The data obtained from a field campaign aimed at observing the flow field downwind of a mountain ridge in the vicinity of Mt. Pleasant airport in the Falkland islands is analysed. From the data analysis, a correlation between the temperature inversion and the difference in temperature between the sea surface and air is established. The seasonal distribution of these phenomena is also explained.
Due to logistic constraints, there were no radiosonde launches performed upstream during the campaign. To obviate that problem, a one-dimensional boundary layer model with a 1.5-order closure scheme, radiation and cloud parameterisations was developed. The model was then used to simulate the upwind characteristics of some particular case studies during which strong downwind flow was observed.
The influence of temperature inversions on the dynamics of trapped lee-waves was simulated through a series of two--dimensional simulations of flow over idealised ridges. The analysis focussed on the effects of topography composed by two ridges and on the effects of an inversion below the ridge summit. These simulations show that the effects of the second ridge can significantly alter the downstream flow and that a temperature inversion below the summit can also induce strong downwind phenomena.
A two-dimensional simulation using the one-dimensional vertical profile from the boundary layer model was performed. The results were in reasonable agreement with the observed data for that day
Removal of polycyclic aromatic hydrocarbons by biosorbents
Introduction: - Polycyclic aromatic hydrocarbons (PAHs) are a group of environmental carcinogens. They are formed during the
incomplete combustion of organic matter. Humans are exposed to PAHs by various sources, including occupational
environments, cigarette smoke, vehicle exhaust, and dietary sources as grilled and flame-broiled food.
- In vivo studies in animals proved that PAHs are associated to cancer, and epidemiologic studies with exposed
workers, especially in coke ovens and aluminium smelters, have shown clear excess of lung cancer and highly
suggestive excesses of bladder cancer.
- These compounds can enter in drinking water sources by precipitation and runoff on the earth’s surface.
- Portuguese legislation for water for human consumption (DL 306/2007) proposes the determination of five PAHs;
limits of the maximum concentration are 0.10 µg/L for total BghiP, BbF, BkF, IcdP, and 0.010 µg/L for BaP.This work was financial suported by the COMPETE program, under the Watercork project
(nº. 2009/552).N/
Increase in ghrelin levels after weight loss in obese Zucker rats is prevented by gastric banding.
Obes Surg. 2007 Dec;17(12):1599-607. Epub 2007 Nov 30.
Increase in ghrelin levels after weight loss in obese Zucker rats is prevented by gastric banding.
Monteiro MP, Ribeiro AH, Nunes AF, Sousa MM, Monteiro JD, Aguas AP, Cardoso MH.
Department of Anatomy and UMIB (Unit for Multidisciplinary Biomedical Research) of ICBAS (Abel Salazar Institute for the Biomedical Sciences), University of Porto, 4099-003 Porto, Portugal. [email protected]
Abstract
BACKGROUND: Gastric banding is thought to decrease appetite in addition to the mechanical effects of food restriction, although this has been difficult to demonstrate in human studies. Our aim was to investigate the changes in orexigenic signals in the obese Zucker rat after gastric banding.
METHODS: Obese Zucker rats (fa/fa) were submitted to gastric banding (GBP), sham gastric banding fed ad libitum (sham), or sham operation with food restriction, pair-fed to the gastric banding group (sham-PF). Lean Zucker rats (fa/+) were used as additional controls. Body weight and food intake were daily recorded for 21 days after surgery when epididymal fat was weighed and fasting ghrelin and hypothalamic NPY mRNA expression were measured.
RESULTS: Gastric banding in obese Zucker rats resulted in a significant decrease of cumulative body weight gain and food intake. Furthermore, gastric banded rats were leaner than Sham-PF, as expressed by a significantly lower epididymal fat weight. Ghrelin levels of gastric banded rats were not increased when compared to sham-operated animals fed ad libitum and were significantly lower than the levels of weight matched sham-PF rats (1116.9 +/- 103.3 g GBP vs 963.2 +/- 54.3 g sham, 3,079.5 +/- 221.6 sham-PF and 2,969.9 +/- 150.9 g lean rats, p < 0.001); hypothalamic NPY mRNA expression was not increased in GBP when compared to sham-operated rats.
CONCLUSION: In obese Zucker rats, GBP prevents the increase in orexigenic signals that occur during caloric deprivation. Our data support the hypothesis that sustained weight loss observed after gastric banding does not depend solely on food restriction
Area Spectrum of Extremal Reissner-Nordstr\"om Black Holes from Quasi-normal Modes
Using the quasi-normal modes frequency of extremal Reissner-Nordstr\"om black
holes, we obtain area spectrum for these type of black holes. We show that the
area and entropy black hole horizon are equally spaced. Our results for the
spacing of the area spectrum differ from that of schwarzschild black holes.Comment: 6 pages, no figure, accepted for publication in Phys. Rev.
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