Mycosis fungoides and pregnancy

Mycosis fungoides is a cutaneous T-cell lymphoma, a subgroup of non-Hodgkin's lymphomas, characterized by skin infiltration and occasionally systemic involvement. The association of pregnancy and mycosis fungoides has not been described previously. A case of mycosis fungoides, stage IVb, in a pregnant woman is reported. Prior to pregnancy, the patient received adriamycin, cyclophosphamide, vincristine prednisolone (CHOP) and bleomycin and total body irradiation. Around the concepcional period she presented a cutaneous relapse palliated with photon radiotherapy. No obstetrics complications were observed during gestation. At 39 week's gestation a cesarean section was performed and a healthy 2900 g boy was delivered. Mycosis fungoides did not worsen during pregnancy and postpartum period. In conclusion mycosis fungoides did not adversely affect pregnancy outcome and gestation did not worsen the malignancy course. This case report may be valuable in managing patients with mycosis fungoides who are currently pregnant or are contemplating pregnancy

Estudio del ciclo genital de las pacientes sometidas a tratamiento con hemodiálisis periódica

[spa] Desde mi época de estudiante, he estado en contacto con la formación del Servicio de Nefrología, Hemodiálisis y Riñón Artificial del Hospital Clínico y Provincial de Barcelona. Mi dedicación posterior a Obstetricia y Ginecología no me hizo perder el contacto con mis antiguos compañeros del Equipo de Nefrología, por lo que he sido consultado en diversas ocasiones a propósito de l o s problemas ginecológicos que presentaban sus enfermas y concretamente por los relativos a las frecuentes metrorragias de las enfermas sometidas al programa de "Hemodiálisis Periódica". Ello me obligó a revisar el tema y pronto puede comprobar que en la literatura médica existían pocos datos relativos al estudio del ciclo genital y sus alteraciones en el caso de las pacientes sometidas a hemodiálisis periódica. En ese sentido, el propósito de la presente tesis ha sido realizar un estudio del ciclo genital de las pacientes con insuficiencia renal crónica, sometidas a tratamiento con hemodiálisis periódicas, en sus aspectos clínicos, hormonal (a los niveles hipofisarios y ováricos) y en lo posible endometrial y vaginal con el fin de aportar algo de luz sobre los trastornos que en se producen el mismo y en especial sobre si existen alteraciones hormonales que expliquen los frecuentes casos de menometrorragia no totalmente justificadas por el efecto de la heparina que dichas pacientes reciben durante la diálisis, ni por las alteraciones en la coagulación de los pacientes urémicos que si bien son parcialmente compensados por las hemodiálisis no logran normalizar totalmente los factores de coagulación

Mycosis fungoides and pregnancy

Mycosis fungoides is a cutaneous T-cell lymphoma, a subgroup of non-Hodgkin's lymphomas, characterized by skin infiltration and occasionally systemic involvement. The association of pregnancy and mycosis fungoides has not been described previously. A case of mycosis fungoides, stage IVb, in a pregnant woman is reported. Prior to pregnancy, the patient received adriamycin, cyclophosphamide, vincristine prednisolone (CHOP) and bleomycin and total body irradiation. Around the concepcional period she presented a cutaneous relapse palliated with photon radiotherapy. No obstetrics complications were observed during gestation. At 39 week's gestation a cesarean section was performed and a healthy 2900 g boy was delivered. Mycosis fungoides did not worsen during pregnancy and postpartum period. In conclusion mycosis fungoides did not adversely affect pregnancy outcome and gestation did not worsen the malignancy course. This case report may be valuable in managing patients with mycosis fungoides who are currently pregnant or are contemplating pregnancy