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Effects of Gene Imbalance on Amyloid Precursor Protein [APP] Expression in Grafts and Recipient Cortex
Outcomes of therapeutic community treatment for personality disorder
Purpose - The paper reviewed quantitative research since 1999 evaluating the effectiveness of democratic therapeutic community (DTC) treatment for individuals with personality disorders (PD) with reference to interpersonal and offending risk outcomes. Design/methodology/approach - A systematic search resulted in the review of ten studies. All of the studies investigated DTCs treating PD in community, inpatient residential and forensic settings. Only peer-reviewed, English-language articles employing a quantitative design were included. Findings - The majority of studies were conducted poorly and of low methodological quality, with limitations located in the representativeness of participants, limited use of control and comparison groups, follow up periods and controls for confounders. Heterogeneity remained in use of measures and limited consideration was given to the validity of interpersonal measures used. While improved interpersonal outcomes post DTC treatment were noted in forensic and residential settings, results were mixed in day and mini TC settings. Inconsistent findings in offending risk outcomes were also indicated. A study with increased methodological rigour indicated residential treatment had limited effects on interpersonal outcomes, when compared to combination treatment (residential TC and step-down treatment). Originality/value - The study provided an evaluation of the limitations of DTC research across a range of settings and highlighted a combination of residential TC and step-down treatment may achieve superior outcomes to residential TC treatment alone in a community inpatient population. Recommendations are made for future research to contribute to the treatment of PD
Nodal/Antinodal Dichotomy and the Two Gaps of a Superconducting Doped Mott Insulator
We study the superconducting state of the hole-doped two-dimensional Hubbard
model using Cellular Dynamical Mean Field Theory, with the Lanczos method as
impurity solver. In the under-doped regime, we find a natural decomposition of
the one-particle (photoemission) energy-gap into two components. The gap in the
nodal regions, stemming from the anomalous self-energy, decreases with
decreasing doping. The antinodal gap has an additional contribution from the
normal component of the self-energy, inherited from the normal-state pseudogap,
and it increases as the Mott insulating phase is approached.Comment: Corrected typos, 4.5 pages, 4 figure
Phosphorus limited growth of the tropical seagrass Syringodium filiforme in carbonate sediments
Hematocrit Values Predict Carotid Intimal-Media Thickness in Obese Patients With Non-Alcoholic Fatty Liver Disease: A Cross-Sectional Study
BACKGROUND:
Literature data suggest with some criticism that full-fledged cardiovascular (CV) events (acute or chronic) are likely predicted by blood components, which are reported to be associated with the presence/severity of non-alcoholic fatty liver disease (NAFLD). This study was aimed at determining which marker(s) derived from blood count, such as white blood cells, neutrophils, neutrophil/lymphocyte ratio, platelet count, hemoglobin, mean corpuscular volume, hematocrit values were associated with ear or subclinical atherosclerosis, in obese patients of various classes suffering from NAFLD.
METHODS:
One hundred consecutive obese patients presenting NAFLD at ultrasound, with low prevalence of co-morbidities and no history or instrumental features of CV diseases, underwent carotid intima-media thickness (IMT) assessment by Doppler ultrasonography. All of them were studied taking into account anthropometric parameters, the metabolic profile, and inflammatory markers.
RESULTS:
White blood cells and neutrophil count showed no statistical association with IMT, which was predicted by the amount of visceral adiposity, as appreciated by ultrasonography. After adjusting for visceral adiposity and smoking status, only age and hematocrit contextually predicted early atherosclerosis, evaluated as IMT. Visceral adiposity was a confounding factor in foreseeing IMT.
CONCLUSION:
Hematocrit values along with the patient's age suggest an initial atherosclerosis, evaluated as IMT, and if this finding is confirmed in larger cohorts, could be added to other canonical CV risk factors. Inferences can be enhanced by future prospective studies that aim to identify the relationships between incident cardio-metabolic cases and this hematologic parameter
Toward Open Integrated Access and Backhaul with O-RAN
Millimeter wave (mmWave) communications has been recently standardized for use in the fifth generation (5G) of cellular networks, fulfilling the promise of multi-gigabit mobile throughput of current and future mobile radio network generations. In this context, the network densification required to overcome the difficult mmWave propagation will result in increased deployment costs. Integrated Access and Backhaul (IAB) has been proposed as an effective mean of reducing densification costs by deploying a wireless mesh network of base stations, where backhaul and access transmissions share the same radio technology. However, IAB requires sophisticated control mechanisms to operate efficiently and address the increased complexity. The Open Radio Access Network (RAN) paradigm represents the ideal enabler of RAN intelligent control, but its current specifications are not compatible with IAB. In this work, we discuss the challenges of integrating IAB into the Open RAN ecosystem, detailing the required architectural extensions that will enable dynamic control of 5G IAB networks. We implement the proposed integrated architecture into the first publiclyavailable Open-RAN-enabled experimental framework, which allows prototyping and testing Open-RAN-based solutions over end-to-end 5G IAB networks. Finally, we validate the framework with both ideal and realistic deployment scenarios exploiting the large-scale testing capabilities of publicly available experimental platforms
Single-boson exchange decomposition of the vertex function
We present a decomposition of the two-particle vertex function of the single-band Anderson impurity model which imparts a physical interpretation of the vertex in terms of the exchange of bosons of three flavors. We evaluate the various components of the vertex for an impurity model corresponding to the half-filled Hubbard model within dynamical mean-field theory. For small values of the interaction almost the entire information encoded in the vertex function corresponds to single-boson exchange processes, which can be represented in terms of the Hedin three-leg vertex and the screened interaction. Also for larger interaction, the single-boson exchange still captures scatterings between electrons and the dominant low-energy fluctuations and provides a unified description of the vertex asymptotics. The proposed decomposition of the vertex does not require the matrix inversion of the Bethe-Salpeter equation. Therefore, it represents a computationally lighter and hence more practical alternative to the parquet decomposition
Polaron formation for a non-local electron-phonon coupling: A variational wave-function study
We introduce a variational wave-function to study the polaron formation when
the electronic transfer integral depends on the relative displacement between
nearest-neighbor sites giving rise to a non-local electron-phonon coupling with
optical phonon modes. We analyze the ground state properties such as the
energy, the electron-lattice correlation function, the phonon number and the
spectral weight. Variational results are found in good agreement with analytic
weak-coupling perturbative calculations and exact numerical diagonalization of
small clusters. We determine the polaronic phase diagram and we find that the
tendency towards strong localization is hindered from the pathological sign
change of the effective next-nearest-neighbor hopping.Comment: 11 page
A note on boundedness of operators in Grand Grand Morrey spaces
In this note we introduce grand grand Morrey spaces, in the spirit of the
grand Lebesgue spaces. We prove a kind of \textit{reduction lemma} which is
applicable to a variety of operators to reduce their boundedness in grand grand
Morrey spaces to the corresponding boundedness in Morrey spaces. As a result of
this application, we obtain the boundedness of the Hardy-Littlewood maximal
operator and Calder\'on-Zygmund operators in the framework of grand grand
Morrey spaces.Comment: 8 page
Magnetic and lattice polaron in Holstein-t-J model
We investigate the interplay between the formation of lattice and magnetic
polaron in the case of a single hole in the antiferromagnetic background. We
present an exact analytical solution of the Holstein-t-J model in infinite
dimensions. Ground state energy, electron-lattice correlation function, spin
bag dimension as well as spectral properties are calculated. The magnetic and
hole-lattice correlations sustain each other, i.e. the presence of
antiferromagnetic correlations favors the formation of the lattice polaron at
lower value of the electron-phonon coupling while the polaronic effect
contributes to reduce the number of spin defects in the antiferromagnetic
background. The crossover towards a spin-lattice small polaron region of the
phase diagram becomes a discontinuous transition in the adiabatic limit.Comment: revtex, 8 eps figures included NEW version. Appendix with a full
proof include
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