Supporting technology instruction through peer tutoring, discussion boards and electronic journals

Given the diverse backgrounds and technical expertise that languageteachers can possess, it is challenging for technology instructors tomeet the needs of individuals during workshops or classes. In thisstudy, we explored the effectiveness of three interventions implementedto help a technology instructor better meet the needs ofindividuals in his class: peer tutoring, asynchronous discussion boardand electronic journal entries. Through the three interventions, theinstructor's role changed from being the provider of solutions toevery problem (firefighter) to being an available coach, able to focushis attention on matters that required it most. The instructorbecame well informed of individuals' challenges and frustrationsthrough discussion board postings and journal entries. Learnersregularly answered each others' questions and provided support andadvice as they acted as peer tutors and as they exchange messages viathe discussion board. A strong group dynamic developed as learnersgrew accustomed to assisting each other regularly. The instructorwas able to adjust lessons according to needs perceived via journalsand discussion board entries. He was also able to focus more attentionon problems in class that required instructor attention (as opposedto questions readily answerable by peers)

The Lyman Alpha Reference Sample: V. The impact of neutral ISM kinematics and geometry on Lyman Alpha escape

We present high-resolution far-UV spectroscopy of the 14 galaxies of the Lyman Alpha Reference Sample; a sample of strongly star-forming galaxies at low redshifts ($0.028 < z < 0.18$). We compare the derived properties to global properties derived from multi band imaging and 21 cm HI interferometry and single dish observations, as well as archival optical SDSS spectra. Besides the Lyman $\alpha$ line, the spectra contain a number of metal absorption features allowing us to probe the kinematics of the neutral ISM and evaluate the optical depth and and covering fraction of the neutral medium as a function of line-of-sight velocity. Furthermore, we show how this, in combination with precise determination of systemic velocity and good Ly$\alpha$ spectra, can be used to distinguish a model in which separate clumps together fully cover the background source, from the "picket fence" model named by Heckman et al. (2011). We find that no one single effect dominates in governing Ly$\alpha$ radiative transfer and escape. Ly$\alpha$ escape in our sample coincides with a maximum velocity-binned covering fraction of $\lesssim 0.9$ and bulk outflow velocities of $\gtrsim 50$ km s$^{-1}$, although a number of galaxies show these characteristics and yet little or no Ly$\alpha$ escape. We find that Ly$\alpha$ peak velocities, where available, are not consistent with a strong backscattered component, but rather with a simpler model of an intrinsic emission line overlaid by a blueshifted absorption profile from the outflowing wind. Finally, we find a strong anticorrelation between H$\alpha$ equivalent width and maximum velocity-binned covering factor, and propose a heuristic explanatory model.Comment: 28 pages, 19 figures, 5 table

The Lyman alpha Reference Sample: Extended Lyman alpha Halos Produced at Low Dust Content

We report on new imaging observations of the Lyman alpha emission line (Lya), performed with the Hubble Space Telescope, that comprise the backbone of the Lyman alpha Reference Sample (LARS). We present images of 14 starburst galaxies at redshifts 0.028 < z < 0.18 in continuum-subtracted Lya, Halpha, and the far ultraviolet continuum. We show that Lya is emitted on scales that systematically exceed those of the massive stellar population and recombination nebulae: as measured by the Petrosian 20 percent radius, RP20, Lya radii are larger than those of Halpha by factors ranging from 1 to 3.6, with an average of 2.4. The average ratio of Lya-to-FUV radii is 2.9. This suggests that much of the Lya light is pushed to large radii by resonance scattering. Defining the "Relative Petrosian Extension" of Lya compared to Halpha, \xi_ext = RP20_Lya / RP20_Ha, we find \xi_ext to be uncorrelated with total Lya luminosity. However \xi_ext is strongly correlated with quantities that scale with dust content, in the sense that a low dust abundance is a necessary requirement (although not the only one) in order to spread Lya photons throughout the interstellar medium and drive a large extended Lya halo.Comment: Published in ApJ Letters ~~ 6 pages using emulateapj, 4 figures ~~ Higher-resolution, larger, nicer jpeg versions of Figures 1 and 2 can be found here: http://xayes.org/pub/press_lars.htm

HST UV Spectroscopy of the Dwarf Starburst Galaxy Pox 186

Studying the galaxies responsible for reionization is often conducted through local reionization-era analogs; however, many of these local analogs are too massive to be representative of the low-mass star-forming galaxies that are thought to play a dominant role in reionization. The local, low-mass dwarf starburst galaxy Pox 186 is one such system with physical conditions representative of a reionization-era starburst galaxy. We present deep ultraviolet (UV) spectroscopy of Pox 186 to study its stellar population and ionization conditions and to compare these conditions to other local starburst galaxies. The new Cosmic Origins Spectrograph data are combined with archival observations to cover $\sim$1150-2000 A and allow for an assessment of Pox 186's stellar population, the relative enrichment of C and O, and the escape of ionizing photons. We detect significant Ly$\alpha$ and low-ionization state absorption features, indicative of previously undetected neutral gas in Pox 186. The C/O relative abundance, log(C/O) = -0.62$\pm$0.02, is consistent with other low-metallicity dwarf galaxies and suggests a comparable star formation history in these systems. We compare UV line ratios in Pox 186 to those of dwarf galaxies and photoionization models, and we find excellent agreement for the ratios utilizing the intense C III], O III], and double-peaked C IV lines. However, the UV and optical He II emission is faint and distinguishes Pox 186 from other local starburst dwarf galaxies. We explore mechanisms that could produce faint He II, which have implications for the low-mass reionization-era galaxies which may have similar ionization conditions.Comment: 22 pages, 9 figures, accepted for publication in The Astrophysical Journa

The Lyman Alpha Reference Sample: III. Properties of the Neutral ISM from GBT and VLA Observations

We present new H I imaging and spectroscopy of the 14 UV-selected star-forming galaxies in the Lyman Alpha Reference Sample (LARS), aimed for a detailed study of the processes governing the production, propagation, and escape of Ly$\alpha$ photons. New H I spectroscopy, obtained with the 100m Green Bank Telescope (GBT), robustly detects the H I spectral line in 11 of the 14 observed LARS galaxies (although the profiles of two of the galaxies are likely confused by other sources within the GBT beam); the three highest redshift galaxies are not detected at our current sensitivity limits. The GBT profiles are used to derive fundamental H I line properties of the LARS galaxies. We also present new pilot H I spectral line imaging of 5 of the LARS galaxies obtained with the Karl G. Jansky Very Large Array (VLA). This imaging localizes the H I gas and provides a measurement of the total H I mass in each galaxy. In one system, LARS 03 (UGC 8335 or Arp 238), VLA observations reveal an enormous tidal structure that extends over 160 kpc from the main interacting systems and that contains $>$10$^9$ M$_{\odot}$ of H I. We compare various H I properties with global Ly$\alpha$ quantities derived from HST measurements. The measurements of the Ly$\alpha$ escape fraction are coupled with the new direct measurements of H I mass and significantly disturbed H I velocities. Our robustly detected sample reveals that both total H I mass and linewidth are tentatively correlated with key Ly$\alpha$ tracers. Further, on global scales, these data support a complex coupling between Ly$\alpha$ propagation and the H I properties of the surrounding medium.Comment: Preprint form, 16 figures, accepted in Ap

Linear scleroderma as a rare cause of enophthalmos: a case report

© 2007 Fernando et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution Licens

PKCθ Regulates T Cell Motility via Ezrin-Radixin-Moesin Localization to the Uropod

Cell motility is a fundamental process crucial for function in many cell types, including T cells. T cell motility is critical for T cell-mediated immune responses, including initiation, activation, and effector function. While many extracellular receptors and cytoskeletal regulators have been shown to control T cell migration, relatively few signaling mediators have been identified that can modulate T cell motility. In this study, we find a previously unknown role for PKCθ in regulating T cell migration to lymph nodes. PKCθ localizes to the migrating T cell uropod and regulates localization of the MTOC, CD43 and ERM proteins to the uropod. Furthermore, PKCθ-deficient T cells are less responsive to chemokine induced migration and are defective in migration to lymph nodes. Our results reveal a novel role for PKCθ in regulating T cell migration and demonstrate that PKCθ signals downstream of CCR7 to regulate protein localization and uropod formation.</p

The Lyman alpha reference sample. VII. Spatially resolved Hα\alpha kinematics

We present integral field spectroscopic observations with the Potsdam Multi Aperture Spectrophotometer of all 14 galaxies in the $z\sim 0.1$ Lyman Alpha Reference Sample (LARS). We produce 2D line of sight velocity maps and velocity dispersion maps from the Balmer $\alpha$ (H$\alpha$) emission in our data cubes. These maps trace the spectral and spatial properties of the LARS galaxies' intrinsic Ly$\alpha$ radiation field. We show our kinematic maps spatially registered onto the Hubble Space Telescope H$\alpha$ and Lyman $\alpha$ (Ly$\alpha$) images. Only for individual galaxies a causal connection between spatially resolved H$\alpha$ kinematics and Ly$\alpha$ photometry can be conjectured. However, no general trend can be established for the whole sample. Furthermore, we compute non-parametric global kinematical statistics -- intrinsic velocity dispersion $\sigma_0$, shearing velocity $v_\mathrm{shear}$, and the $v_\mathrm{shear}/\sigma_0$ ratio -- from our kinematic maps. In general LARS galaxies are characterised by high intrinsic velocity dispersions (54\,km\,s$^{-1}$ median) and low shearing velocities (65\,km\,s$^{-1}$ median). $v_\mathrm{shear}/\sigma_0$ values range from 0.5 to 3.2 with an average of 1.5. Noteworthy, five galaxies of the sample are dispersion dominated systems with $v_\mathrm{shear}/\sigma_0 <1$ and are thus kinematically similar to turbulent star forming galaxies seen at high redshift. When linking our kinematical statistics to the global LARS Ly$\alpha$ properties, we find that dispersion dominated systems show higher Ly$\alpha$ equivalent widths and higher Ly$\alpha$ escape fractions than systems with $v_\mathrm{shear}/\sigma_0 > 1$. Our result indicates that turbulence in actively star-forming systems is causally connected to interstellar medium conditions that favour an escape of Ly$\alpha$ radiation.Comment: 26 pages, 15 figures, accepted for publication in A&

Weight Loss Programs May Have Beneficial or Adverse Effects on Fat Mass and Insulin Sensitivity in Overweight and Obese Black Women

OBJECTIVE: Weight loss interventions have produced little change in insulin sensitivity in black women, but mean data may obscure metabolic benefit to some and adverse effects for others. Accordingly, we analyzed insulin sensitivity relative to fat mass change following a weight loss program. DESIGN AND METHODS: Fifty-four black women (BMI range 25.9 to 54.7 kg/m(2)) completed the 6-month program that included nutrition information and worksite exercise facilities. Fat mass was measured by dual-energy X-ray absorptiometry, and insulin sensitivity index (S(I)) was calculated from an insulin-modified intravenous glucose tolerance test using the minimal model. RESULTS: Baseline S(I) (range 0.74 to 7.58 l/mU(−1)•min(−1)) was inversely associated with fat mass (r = −0.516, p < 0.001), independent of age. On average, subjects lost fat mass (baseline 40.8 ± 12.4 to 39.4 ± 12.6 kg [mean ± SD], P < 0.01), but 17 women (32 %) actually gained fat mass. S(I) for the group was unchanged (baseline 3.3 ± 1.7 to 3.2 ± 1.6, P = 0.67). However, the tertile with greatest fat mass loss (−3.6 kg, range −10.7 to −1.7 kg) improved insulin sensitivity (S(I) +0.3 ± 1.2), whereas the tertile with net fat mass gain (+0.9 kg, range −0.1 to +3.8 kg) had reduced insulin sensitivity (S(I) −0.7 ± 1.3) from baseline values (P < 0.05 by ANOVA). CONCLUSIONS: Black women in a weight loss program who lose fat mass may have improved insulin sensitivity, but fat mass gain with diminished sensitivity is common. Additional support for participants who fail to achieve fat mass loss early in an intervention may be required for success