Work statistics, irreversible heat and correlations build-up in joining two spin chains

We investigate the influences of quantum many-body effects, such as criticality and the existence of factorisation fields, in the thermodynamic cost of establishing a bonding link between two independent quantum spin chains. We provide a physical interpretation of the behavior of irreversible work spent in such process by linking the phenomenology of such quantities to the properties of the spectrum of the systemComment: 9 pages, 8 figures. Contribution to the FQMT13 special volum

Transient fluctuation theorem in closed quantum systems

Our point of departure are the unitary dynamics of closed quantum systems as generated from the Schr\"odinger equation. We focus on a class of quantum models that typically exhibit roughly exponential relaxation of some observable within this framework. Furthermore, we focus on pure state evolutions. An entropy in accord with Jaynes principle is defined on the basis of the quantum expectation value of the above observable. It is demonstrated that the resulting deterministic entropy dynamics are in a sense in accord with a transient fluctuation theorem. Moreover, we demonstrate that the dynamics of the expectation value are describable in terms of an Ornstein-Uhlenbeck process. These findings are demonstrated numerically and supported by analytical considerations based on quantum typicality.Comment: 5 pages, 6 figure

Efficient solar cells by space processing

Thin films of electron beam evaporated silicon were deposited on molybdenum, tantalum, tungsten and molybdenum disilicide under ultrahigh vacuum conditions. Mass spectra from a quadrapole residual gas analyzer were used to determine the partial pressure of 13 residual gases during each processing step. Surface contamination and interdiffusion were monitored by in situ Auger electron spectrometry. The presence of phosphorus in the silicon was responsible for attaining elevated temperatures with silicide formations. Heteroepitaxial silicon growth was sensitive to the presence of oxygen during deposition, the rate and length of deposition as well as the substrate orientation

Derivation of Boltzmann Principle

We present a derivation of Boltzmann principle $S_{B}=k_{B}\ln \mathcal{W}$ based on classical mechanical models of thermodynamics. The argument is based on the heat theorem and can be traced back to the second half of the nineteenth century with the works of Helmholtz and Boltzmann. Despite its simplicity, this argument has remained almost unknown. We present it in a modern, self-contained and accessible form. The approach constitutes an important link between classical mechanics and statistical mechanics

Water extract of Cryphaea heteromalla (Hedw.) D. Mohr bryophyte as a natural powerful source of biologically active compounds

Bryophytes comprise of the mosses, liverworts, and hornworts. Cryphaea heteromalla, (Hedw.) D. Mohr, is a non-vascular lower plant belonging to mosses group. To the date, the most chemically characterized species belong to the liverworts, while only 3.2% and 8.8% of the species belonging to the mosses and hornworts, respectively, have been investigated. In this work, we present Folin–Ciocalteu and oxygen radical absorbance capacity (ORAC) data related to crude extracts of C. heteromalla obtained by three different extraction solvents: pure water (WT), methanol:water (80:20 v/v) (MET), and ethanol:water (80:20 v/v) (ETH). The water extract proved to be the best solvent showing the highest content of biophenols and the highest ORAC value. The C. heteromalla-WT extract was investigated by HPLC-TOF/MS (High Performance Liquid Chromatography-Time of Flight/Mass Spectrometry) allowing for the detection of 14 compounds, five of which were phenolic compounds, derivatives of benzoic, caffeic, and coumaric acids. Moreover, the C. heteromalla WT extract showed a protective effect against reactive oxygen species (ROS) generation induced by tert-butyl hydroperoxide (TBH) on the murine NIH-3T3 fibroblast cell line

CTGF drives autophagy, glycolysis and senescence in cancer-associated fibroblasts via HIF1 activation, metabolically promoting tumor growth

Previous studies have demonstrated that loss of caveolin-1 (Cav-1) in stromal cells drives the activation of the TGF-β signaling, with increased transcription of TGF-β target genes, such as connective tissue growth factor (CTGF). In addition, loss of stromal Cav-1 results in the metabolic reprogramming of cancer-associated fibroblasts, with the induction of autophagy and glycolysis. However, it remains unknown if activation of the TGF-β / CTGF pathway regulates the metabolism of cancer-associated fibroblasts. Therefore, we investigated whether CTGF modulates metabolism in the tumor microenvironment. For this purpose, CTGF was overexpressed in normal human fibroblasts or MDA-MB-231 breast cancer cells. Overexpression of CTGF induces HIF-1α-dependent metabolic alterations, with the induction of autophagy/mitophagy, senescence, and glycolysis. Here, we show that CTGF exerts compartment-specific effects on tumorigenesis, depending on the cell-type. In a xenograft model, CTGF overexpressing fibroblasts promote the growth of co-injected MDA-MB-231 cells, without any increases in angiogenesis. Conversely, CTGF overexpression in MDA-MB-231 cells dramatically inhibits tumor growth in mice. Intriguingly, increased extracellular matrix deposition was seen in tumors with either fibroblast or MDA-MB-231 overexpression of CTGF. Thus, the effects of CTGF expression on tumor formation are independent of its extracellular matrix function, but rather depend on its ability to activate catabolic metabolism. As such, CTGF-mediated induction of autophagy in fibroblasts supports tumor growth via the generation of recycled nutrients, whereas CTGF-mediated autophagy in breast cancer cells suppresses tumor growth, via tumor cell self-digestion. Our studies shed new light on the compartment-specific role of CTGF in mammary tumorigenesis, and provide novel insights into the mechanism(s) generating a lethal tumor microenvironment in patients lacking stromal Cav-1. As loss of Cav-1 is a stromal marker of poor clinical outcome in women with primary breast cancer, dissecting the downstream signaling effects of Cav-1 are important for understanding disease pathogenesis, and identifying novel therapeutic targets

Quantum Fluctuation Relations for the Lindblad Master Equation

An open quantum system interacting with its environment can be modeled under suitable assumptions as a Markov process, described by a Lindblad master equation. In this work, we derive a general set of fluctuation relations for systems governed by a Lindblad equation. These identities provide quantum versions of Jarzynski-Hatano-Sasa and Crooks relations. In the linear response regime, these fluctuation relations yield a fluctuation-dissipation theorem (FDT) valid for a stationary state arbitrarily far from equilibrium. For a closed system, this FDT reduces to the celebrated Callen-Welton-Kubo formula

The distribution of work performed on a NIS junction

We propose an experimental setup to measure the work performed in a normal-metal/insulator/ superconducting (NIS) junction, subjected to a voltage change and in contact with a thermal bath. We compute the performed work and argue that the associated heat release can be measured experimentally. Our results are based on an equivalence between the dynamics of the NIS junction and that of an assembly of two-level systems subjected to a circularly polarised field, for which we can determine the work-characteristic function exactly. The average work dissipated by the NIS junction, as well as its fluctuations, are determined. From the work characteristic function, we also compute the work probability-distribution and show that it does not have a Gaussian character. Our results allow for a direct experimental test of the Crooks–Tasaki fluctuation relation.Program of Recruitment of Post Doctoral Researchers for the Portuguese Scientific and Technological System, within the Operational Program Human Potential (POPH) of the QREN, participated by the European Social Fund (ESF) and national funds of the Portuguese Ministry of Education and Science (MEC); Danish National Research Foundation, Project No. DNRF58; National Natural Science Foundation of China, Grant No. 1147425

Thermodynamics of adiabatic feedback control

We study adaptive control of classical ergodic Hamiltonian systems, where the controlling parameter varies slowly in time and is influenced by system's state (feedback). An effective adiabatic description is obtained for slow variables of the system. A general limit on the feedback induced negative entropy production is uncovered. It relates the quickest negentropy production to fluctuations of the control Hamiltonian. The method deals efficiently with the entropy-information trade off.Comment: 6 pages, 1 figur

Thermodynamic anomaly of the free damped quantum particle: the bath perspective

A possible definition of the specific heat of open quantum systems is based on the reduced partition function of the system. For a free damped quantum particle, it has been found that under certain conditions, this specific heat can become negative at low temperatures. In contrast to the conventional approaches focusing on the system degree of freedom, here we concentrate on the changes induced in the environment when the system is coupled to it. Our analysis is carried out for an Ohmic environment consisting of harmonic oscillators and allows to identify the mechanism by which the specific heat becomes negative. Furthermore, the formal condition for the occurrence of a negative specific heat is given a physical interpretation in terms of the total mass of bath oscillators and the system mass.Comment: 7 pages, 1 figure, final version after one round of refereein