1,010 research outputs found
Liquid rocket performance computer model with distributed energy release Interim final report, 15 Aug. 1969 - 15 Aug. 1970
Liquid propellant rocket engine performance computer program with distributed energy releas
An Unfinished Canvas: District Capacity and the Use of New State Funds for Arts Education in California
Questions about district leadership and capacity -- particularly in light of the new funding -- served as the impetus for this study. Through a survey of leaders in 385 districts, we assessed districts' capacity with respect to arts education, explored early spending choices, and examined the relationship between the two. We also studied changes in arts education since the new resources became available and worked to understand the barriers that continue to stand in the way of comprehensive arts education for all California students
Generalized power expansions in cosmology
It is given an algorithm to obtain generalized power asymptotic expansions of
the solutions of the Einstein equations arising for several homogeneous
cosmological models. This allows to investigate their behavior near the initial
singularity or for large times. An implementation of this algorithm in the CAS
system Maple V Release 4 is described and detailed calculations for three
equations are shown.Comment: 22 pages, LaTeX, elsart.sty. To be published in Computer Physics
Communications Thematic Issue "Computer Algebra in Physics Research
Heavy Fermion Stabilization of Solitons in 1+1 Dimensions
We find static solitons stabilized by quantum corrections in a
(1+1)-dimensional model with a scalar field chirally coupled to fermions. This
model does not support classical solitons. We compute the renormalized energy
functional including one-loop quantum corrections. We carry out a variational
search for a configuration that minimizes the energy functional. We find a
nontrivial configuration with fermion number whose energy is lower than the
same number of free fermions quantized about the translationally invariant
vacuum. In order to compute the quantum corrections for a given background
field we use a phase-shift parameterization of the Casimir energy. We identify
orders of the Born series for the phase shift with perturbative Feynman
diagrams in order to renormalize the Casimir energy using perturbatively
determined counterterms. Generalizing dimensional regularization, we
demonstrate that this procedure yields a finite and unambiguous energy
functional.Comment: 27 papes Latex, equation labels corrected, version to be published in
Nucl. Phys.
Ultrasound morphology of carotid plaque and its link with lipid: protein content and 3d microstructure of the plaque.
the 22nd Meeting of the European Society of Neurosonology and Cerebral Hemodynamics (ESNCH), 19-21 May 2017. Berlin, Germany, and published in the International Journal of Stroke 12(1S): 57 (Poster 101), May 2017. ISSN: 1747-4930, eISSN: 1747-4949
Multi-layered control of Galectin-8 mediated autophagy during adenovirus cell entry through a conserved PPxY motif in the viral capsid.
Cells employ active measures to restrict infection by pathogens, even prior to responses from the innate and humoral immune defenses. In this context selective autophagy is activated upon pathogen induced membrane rupture to sequester and deliver membrane fragments and their pathogen contents for lysosomal degradation. Adenoviruses, which breach the endosome upon entry, escape this fate by penetrating into the cytosol prior to autophagosome sequestration of the ruptured endosome. We show that virus induced membrane damage is recognized through Galectin-8 and sequesters the autophagy receptors NDP52 and p62. We further show that a conserved PPxY motif in the viral membrane lytic protein VI is critical for efficient viral evasion of autophagic sequestration after endosomal lysis. Comparing the wildtype with a PPxY-mutant virus we show that depletion of Galectin-8 or suppression of autophagy in ATG5-/- MEFs rescues infectivity of the PPxY-mutant virus while depletion of the autophagy receptors NDP52, p62 has only minor effects. Furthermore we show that wildtype viruses exploit the autophagic machinery for efficient nuclear genome delivery and control autophagosome formation via the cellular ubiquitin ligase Nedd4.2 resulting in reduced antigenic presentation. Our data thus demonstrate that a short PPxY-peptide motif in the adenoviral capsid permits multi-layered viral control of autophagic processes during entry
Receipt to Ogden Goelet concerning rent of Maid of honor
https://digitalcommons.salve.edu/goelet-personal-expenses/1086/thumbnail.jp
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