771 research outputs found

    The Neuroliberal Wellbeing Agenda - A Trojan Horse? An enquiry into the potential space for repositioning responses to wellbeing intervention strategies as intrapersonal resistance

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    There has been a reported increase in the number of children and young people (CYP) in England identifying as having mental health issues. The most recently commissioned national survey (NHS Digital, 2018) identified prevalence rates of 1:8 5-19 year olds having at least one mental disorder. When published, this created alarm across the media resulting in the reporting of a ‘crisis’ in CYP’s mental health, which impacted public perceptions of student wellbeing. As a consequence, the mental health narratives within education, (in respect of the ‘affective turn’) intensified, leading to an increase in wellbeing intervention strategies and school-based practices. However, despite a raft of intervention measures in educational settings, CYP’s mental health issues appears to be growing exponentially, with waiting times for referral to services like CAMHS getting longer. When CYP are seen by clinical services, this often involves treatment interventions that include medication and psychological therapies. This research enquiry involves a search for ‘gaps’ and ‘spaces’ outside of the current wellbeing narrative, which seeks to reposition explanations for reported ‘mental health disorders’ as intrapsychic defences, a response to threats around the core identity. The research enquiry critically assesses the constructs of the Wellbeing Agenda around four specific themes. (1) Representation of mental health in CYP - through an evaluation of the 2018 report findings and assessment of what this says about mental health issues in CYP. (2) Alienation - CYP are experiencing the same types of alienation found in adult populations working within monopoly-capitalist economies, created by education marketisation which in turn creates mental distress. (3) Resilience - the implementation of wellbeing strategies that use concepts based upon positive psychology are harmful and dehumanising. (4) Resistance - using a combination of sociological and psychological theories of resistance ‘intrapersonal’ resistance is explained, as a means to defend against intrusive wellbeing measures that seek to use resilience as a means to ‘fold back’ resistance. The approach taken to this issue is ‘pure’ research (Patel and Patel, 2019) utilising applied Resistance Theory as method (Matias, 2021). The critical evaluation has been completed using a modification of Evaluative Inquiry (Fochler and DeRijcke, 2017). This evaluation has reflected Bacchi’s (2016) comments relating to political ontology and the ‘positioning’ of problems to serve specific political agendas, in this regard the neoliberal trope of ‘personal responsibility’

    The folic acid metabolism gene mel-32/Shmt is required for normal cell cycle lengths in Caenorhabditis elegans

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    Neural tube defects are common and serious birth defects in which the brain and/or spinal cord are exposed outside the body. Supplementation of foods with folic acid, an essential vitamin, is linked to a lower risk of neural tube defects; however, the mechanisms by which folic acid influence neural tube defect risk are unclear. Our research seeks to identify the basic cellular roles of known folic acid metabolism genes during morphogenesis using the roundworm Caenorhabditis elegans (C. elegans) as a simple model system. Here, we used live imaging to characterize defects in embryonic development when mel-32 is depleted. mel-32 is an essential folic acid metabolism gene in C. elegans and a homolog to the mammalian enzyme serine hydroxymethyltransferase (Shmt). Disruption of mel-32 resulted in a doubling or tripling of cell cycle lengths and a lack of directed cell movement during embryogenesis. However, the order of cell divisions, as determined by lineage analysis, is unchanged compared to wild type embryos. These results suggest that mel32/Shmt is required for normal cell cycle lengths in C. elegans

    Oral cancer stem cells - properties and consequences

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    Research on cancer stem cells (CSCs) has greatly increased in the field of medicine and pathology; however, some conceptual misunderstandings are still present among the public as well as within the general scientific community that is not yet familiar with the subject. The very first problem is the misinterpretation of CSCs as a synonym of their normal counterparts, the well-known stem cells (SCs). Particularly in Dentistry, another common mistake is the misinterpretation of oral CSCs as normal tooth-derived SCs. The present review aims to clarify important concepts related to normal SCs and CSCs, as well as discuss the relevance of CSCs to the development, metastasis and therapy resistance of oral squamous cell carcinoma

    Closing the Nuclear Fuel Cycle with a Simplified Minor Actinide Lanthanide Separation Process (ALSEP) and Additive Manufacturing

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    Expanded low-carbon baseload power production through the use of nuclear fission can be enabled by recycling long-lived actinide isotopes within the nuclear fuel cycle. This approach provides the benefits of (a) more completely utilizing the energy potential of mined uranium, (b) reducing the footprint of nuclear geological repositories, and (c) reducing the time required for the radiotoxicity of the disposed waste to decrease to the level of uranium ore from one hundred thousand years to a few hundred years. A key step in achieving this goal is the separation of long-lived isotopes of americium (Am) and curium (Cm) for recycle into fast reactors. To achieve this goal, a novel process was successfully demonstrated on a laboratory scale using a bank of 1.25-cm centrifugal contactors, fabricated by additive manufacturing, and a simulant containing the major fission product elements. Americium and Cm were separated from the lanthanides with over 99.9% completion. The sum of the impurities of the Am/Cm product stream using the simulated raffinate was found to be 3.2 × 10−3 g/L. The process performance was validated using a genuine high burnup used nuclear fuel raffinate in a batch regime. Separation factors of nearly 100 for 154Eu over 241Am were achieved. All these results indicate the process scalability to an engineering scale

    Grounded in Relationships of Support: Indigenous Teacher Mentorship in the Rural West

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    This article explores the power of Indigenous teacher mentorship as essential to address “the change in point of view” long called for in Indigenous education. Drawing from a longitudinal, ethnographic study of an Indigenous teacher education program in a predominantly rural, high need region, we examine the basic questions: What do Indigenous master teachers uniquely bring to teacher education? In what ways do Indigenous master teachers support the development of socially, culturally, linguistically, and place-responsive teachers? Using the theoretical frameworks of Tribal Critical Race Theory (TribalCrit) and situated learning, our findings elucidate the importance of Indigenous mentorship for re-membering and re-claiming Indigenous epistemologies, ontologies, and axiologies in relational and intergenerational learning—practices that interrupt coloniality in teacher education and school leadership. Discussion of Indigenous teacher mentorship centers the importance of relationships between people and place in teaching and learning and asks educators and school leaders to conceptualize Indigenous teacher education as a long-term project of tribal nation building and community wellbeing

    Effectiveness of Online Cancer Education for Nurses and Allied Health Professionals; a Systematic Review Using Kirkpatrick Evaluation Framework

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    Embedding online learning within higher education can provide engaging, cost-effective, interactive and flexible education. By evaluating the impact, outcomes and pedagogical influence of online cancer and education, future curricula can be shaped and delivered by higher education providers to better meet learner, health care provider and educational commissioners’ requirements for enhanced patient care and service delivery needs. Using the Kirkpatrick’s four-level model of educational evaluation, a systematic review of the effectiveness of online cancer education for nurses and allied health professionals was conducted. From 101 articles, 30 papers were included in the review. Educational theory is not always employed. There is an absence of longitudinal studies to examine impact; an absence of reliability and/or validity testing of measures, limited experimental designs taking account of power and few attempts to mitigate bias. There is, however, an emerging innovative use of mobile/spaced learning techniques. Evidence for clinical and educational effectiveness is weak offering insights into experiences and participant perceptions rather than concrete quantitative data and patient-reported outcomes. More pedagogical research is merited to inform effective evaluation of online cancer education, which incorporates and demonstrates a longer-term impact

    Promoting influenza vaccine for children

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    This autumn influenza vaccine will again be offered to all 2- and 3-year-olds in general practice. In addition, all children in clinical risk groups aged 6 months and above should be offered the vaccine. Children in primary school years from reception class to year 4 will also be offered the vaccine as part of the on-going extension of influenza vaccination to healthy children. Since the start of the paediatric programme, transmission of influenza has reduced across all age groups in those parts of the country vaccinating all children of primary school age. Children under 5 years of age have the highest rate of hospital admissions for influenza. However, many parents do not think that influenza is a serious illness and it is the vaccine they are most likely to decline. Health professionals are the most trusted source of advice and information about vaccination, so staff in general practice have a crucial role to play in recommending this vaccine to parents. Health professionals are the most trusted source of advice and information about vaccination, so practice nurses have a crucial role to play in recommending the influenza vaccine to parents and increasing uptake </jats:p

    Endomarketing y fidelización de clientes en la empresa JDT, Los Olivos 2022

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    El presente estudio tuvo como objetivo establecer la relación entre endomarketing y fidelización de clientes en la empresa JDT, Los Olivos 2022. Para ello, se realizó una investigación de tipo aplicada, con diseño no experimental-transversal y correlacional con enfoque cuantitativo. La muestra estuvo conformada por 42 colaboradores del área de atención al cliente y ventas de servicios, para el cual se aplicó un cuestionario compuesto de 26 ítems medidos mediante una escala ordinal, dicho instrumento fue evaluado y aprobado previamente por expertos en el tema, obteniendo además un nivel de confiabilidad muy alto. La información obtenida se procesó mediane la estadística descriptiva a través de tablas de frecuencia y tablas cruzadas y la estadística inferencial mediante el coeficiente de correlación Rho de Spearman. Se concluyo que, existe una relación positiva media de 0.679 entre endomarketing y fidelización de clientes, siendo las dimensiones calidad e incentivos como las que mayor correlación positiva tuvieron con la variable endomarketing y fiabilidad e información como las menos correlacionadas

    Family and home correlates of television viewing in 12–13 year old adolescents: The Nepean Study

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    BACKGROUND: Few young people meet television viewing guidelines. PURPOSE: To determine the association between factors in the family and home environment and watching television, including videos and DVDs, in early adolescence. METHODS: Cross-sectional, self-report survey of 343 adolescents aged 12–13 years (173 girls), and their parents (338 mothers, 293 fathers). Main measures were factors in the family and home environment potentially associated with adolescents spending ≥ 2 hours per day in front of the television. Factors examined included family structure, opportunities to watch television/video/DVDs, perceptions of rules and regulations on television viewing, and television viewing practices. RESULTS: Two-thirds of adolescents watched ≥ 2 hours television per day. Factors in the family and home environment associated with adolescents watching television ≥ 2 hours per day include adolescents who have siblings (Adjusted Odds Ratio [95%CI] AOR = 3.0 [1.2, 7.8]); access to pay television (AOR = 2.0 [1.1, 3.7]); ate snacks while watching television (AOR = 3.1 [1.8, 5.4]); co-viewed television with parents (AOR = 2.3 [1.3, 4.2]); and had mothers who watched ≥ 2 hours television per day (AOR = 2.4 [1.3, 4.6]). CONCLUSION: There are factors in the family and home environment that influence the volume of television viewed by 12–13 year olds. Television plays a central role in the family environment, potentially providing a means of recreation among families of young adolescents for little cost. Interventions which target family television viewing practices and those of parents, in particular, are more likely to be effective than interventions which directly target adolescent viewing times
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