3,939 research outputs found
Warmth and Competence Perceptions of Female Job Candidates: Who Gets Hired?
This study explores how warmth and competence perceptions affect hireability of a female job candidate. The mixed model of stereotype content identifies warmth and competence as the two basic dimensions of person-perception, and research has shown a compensatory relationship between these two dimensions, especially for women. This study explores this compensatory effect for women in a hiring situation. Two samples, one of college students (n = 301) and another of MTurk participants (n = 256), read a description of a female job candidate of either high or low competence and either high, low, or no mention of warmth, and then rated her hireability. Candidates had the greatest hireability when high in competence, and competence had a greater effect on hireability than warmth. Warmth and competence perceptions were positively related, reflecting a halo effect, such that higher warmth was inferred from higher competence. Implications for hiring decisions of female professionals are discussed
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Cohesin cleavage by separase is enhanced by a substrate motif distinct from the cleavage site.
Chromosome segregation begins when the cysteine protease, separase, cleaves the Scc1 subunit of cohesin at the metaphase-to-anaphase transition. Separase is inhibited prior to metaphase by the tightly bound securin protein, which contains a pseudosubstrate motif that blocks the separase active site. To investigate separase substrate specificity and regulation, here we develop a system for producing recombinant, securin-free human separase. Using this enzyme, we identify an LPE motif on the Scc1 substrate that is distinct from the cleavage site and is required for rapid and specific substrate cleavage. Securin also contains a conserved LPE motif, and we provide evidence that this sequence blocks separase engagement of the Scc1 LPE motif. Our results suggest that rapid cohesin cleavage by separase requires a substrate docking interaction outside the active site. This interaction is blocked by securin, providing a second mechanism by which securin inhibits cohesin cleavage
Negative relationships between the nutrient and carbohydrate content of the seagrass Thalassia testudinum
This study documents relationships between plant nutrient content and rhizome carbohydrate content of a widely distributed seagrass species, Thalassia testudinum, in Florida. Five distinct seagrass beds were sampled for leaf nitrogen, leaf phosphorus, and rhizome carbohydrate content from 1997 to 1999. All variables displayed marked intra- and inter- regional variation. Elemental ratios (mean N:P ± S.E.) were lowest for Charlotte Harbor (9.9 ± 0.2) and highest for Florida Bay (53.5 ± 0.9), indicating regional shifts in the nutrient content of plant material. Rhizome carbohydrate content (mean ± S.E.) was lowest for Anclote Keys (21.8 ± 1.6 mg gâ1 FM), and highest for Homosassa Bay (40.7 ± 1.7 mg gâ1 FM). Within each region, significant negative correlations between plant nutrient and rhizome carbohydrate content were detected; thus, nutrient-replete plants displayed low carbohydrate content, while nutrient-deplete plants displayed high carbohydrate content. Spearman\u27s rank correlations between nutrient and carbohydrate content varied from a minimum in Tampa Bay (Ï = â0.2) to a maximum in Charlotte Harbor (Ï = â0.73). Linear regressions on log-transformed data revealed similar trends. This consistent trend across five distinct regions suggests that nutrient supply may play an important role in the regulation of carbon storage within seagrasses. Here we present a new hypothesis for studies which aim to explain the carbohydrate dynamics of benthic plants
Mobilisation des organismes communautaires pour la refonte du programme de formation médicale prédoctorale
Implication Statement
As part of its social accountability mission, the University of Ottawa Faculty of Medicine invited community service learning (CSL) partner organizations to a guided, virtual conversation on April 12, 2021 to contribute to the future strategic directions for our curriculum. Representatives of 15 organizations participated and provided insights into how they perceive CSL students, the Faculty of Medicine, and the process of assessment. This workshop forged stronger bonds between the university and these community organizations and led to recommendations for their greater involvement going forward, an approach that could be considered by other Faculties of Medicine.ĂnoncĂ© des implications de la recherche
Dans le cadre de sa mission de responsabilitĂ© sociale, la FacultĂ© de mĂ©decine de lâUniversitĂ© dâOttawa a invitĂ© les organismes partenaires de lâapprentissage par le service communautaire (ASC) Ă contribuer aux futures orientations stratĂ©giques de notre programme dâĂ©tudes par le biais dâune discussion virtuelle guidĂ©e, tenue le 12 avril 2021. Les reprĂ©sentants des 15 organismes qui y ont participĂ© ont donnĂ© leur avis sur la façon dont ils perçoivent les Ă©tudiants en ASC, la FacultĂ© de mĂ©decine et le processus dâĂ©valuation. Cet atelier a permis de resserrer les liens entre lâuniversitĂ© et ces organismes communautaires et a dĂ©bouchĂ© sur des recommandations visant Ă renforcer leur participation Ă lâavenir, une approche qui pourrait ĂȘtre envisagĂ©e par dâautres facultĂ©s de mĂ©decine
Understanding adolescent health risk behaviour and socioeconomic position:A grounded theory study of UK young adults
Health risk behaviours such as tobacco smoking, excessive alcohol consumption, drug use, unhealthy diet and unprotected sexual intercourse contribute to the global burden of nonâcommunicable diseases and are often initiated in adolescence. An individualistic focus on âhealth risk behavioursâ has resulted in behaviour change strategies that are potentially ineffective and increase inequalities. We conducted a grounded theory study of 25 young adults to increase the limited qualitative evidence base surrounding young people, health risk behaviours and socioeconomic inequalities. We found that health risk behaviours were perceived as class markers, manifesting as class stigma, leading some participants from lower socioeconomic backgrounds to employ strategies to avoid such behaviours. Peers and family were core constructs for understanding the relationship between health risk behaviours and socioeconomic life trajectories. However, individualism and choice were consistently expressed as the overriding narrative for understanding health risk behaviour and socioeconomic position during the transition to adulthood. The use of âpersonal responsibilityâ discourse by young adults, we argue, highlights the need for a public health focus on achieving structural changes as opposed to individualised approaches to avoid reinforcing neoliberal ideologies that serve to marginalise and maintain social inequalities
Mutualisms drive plant trait evolution beyond interactionârelated traits
Mutualisms have driven the evolution of extraordinary structures and behavioural traits, but their impact on traits beyond those directly involved in the interaction remains unclear. We addressed this gap using a highly evolutionarily replicated system â epiphytes in the Rubiaceae forming symbioses with ants. We employed models that allow us to test the influence of discrete mutualistic traits on continuous nonâmutualistic traits. Our findings are consistent with mutualism shaping the pace of morphological evolution, strength of selection and longâterm mean of nonâmutualistic traits in function of mutualistic dependency. While specialised and obligate mutualisms are associated with slower trait change, less intimate, facultative and generalist mutualistic interactions â which are the most common â have a greater impact on nonâmutualistic trait evolution. These results challenge the prevailing notion that mutualisms solely affect the evolution of interactionârelated traits via stabilizing selection and instead demonstrate a broader role for mutualisms in shaping trait evolution
Field Introgression of \u3ci\u3eDiabrotica barberi\u3c/i\u3e and \u3ci\u3eDiabrotica longicornis\u3c/i\u3e (Coleoptera: Chrysomelidae) Based on Genetic and Morphological Characters
Diabrotica barberi Smith & Lawrence and Diabrotica longicornis (Say) (Coleoptera: Chrysomelidae) are considered to be sister species, and it has been proposed that the two species may hybridize under field conditions. The objective of this study was to examine genetic and morphological characters of D. barberi and D. longicornis for evidence of field introgression. Both species were collected from sympatric and allopatric areas. Amplified fragment length polymorphisms and morphological characters (color and head capsule width) were used to examine variation within and among populations of D. barberi and D. longicornis. Relatively little of the overall genetic variation was explained by the putative species designation, and most of the genetic variation, both between and within species, was found within populations. In addition, genetic differences were not correlated with geographic location. Beetle color did differ significantly between putative species, with the darkest individuals occurring at the most distal portions of the ranges. Head capsule width varied significantly among populations, but not among species. Both genetic and morphological data support the hypothesis that introgression is occurring between species in the area of sympatry
Clinical stakeholders' opinions on the use of selective decontamination of the digestive tract in critically ill patients in intensive care units : an international Delphi study
Peer reviewedPublisher PD
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