719 research outputs found
Family-Based Interventions Impact on Pediatric Obesity
Background: Obesity rates among children in the United States have been on the rise, with 19.7% of children aged 2-19 classified as obese (CDC, 2022). Low socioeconomic status is a risk factor for pediatric obesity,Children from low-income households are more likely to be overweight or obese than their peers from higher economic backgrounds. Obesity can lead to serious and chronic health problems such as diabetes, high blood pressure, and breathing difficulties, and is also a risk factor for leading causes of death in adults including stroke, cardiovascular disease, and cancer (CDC, 2022). Educational interventions and access to exercise resources may offer promising solutions for addressing pediatric obesity and improving health outcomes. Objective: The object of the proposal is to conduct research on obesity trends and educational interventions to combat obesity. The research proposal will then investigate the effectiveness of a specific evidence-based educational intervention and resources provided to families in reducing obesity rates. The proposal intends to determine whether these interventions and resources can contribute to a decline in obesity rates. Method: The proposal will consist of a quasi experimental design. The convenience sample will consist of low-income families with children 4-11 years of age that have a BMI greater than 30. Sample size will include 150 children recruited through pediatric doctors offices in Marin County. The participants will be given a pre test questionnaire, and a post test after the intervention.https://scholar.dominican.edu/nursing-student-research-posters/1033/thumbnail.jp
Estudi comparatiu de la publicació científica de la UPC i l’Escola de Camins vs.altres universitats d’àmbit internacional (2009-2018)
L'informe se centra en la publicació científica especialitzada en l'àmbit temàtic propi de l'Escola de Camins: l'enginyeria civil. Es comparen indicadors bibliomètrics de la UPC i l'Escola de Camins amb els d'altres universitats internacionals amb activitat de recerca notable en l'àmbit de l'enginyeria civilPostprint (published version
Mice Lacking Functional Fas Death Receptors Are Protected from Kainic Acid-Induced Apoptosis in the Hippocampus
© 2014, Springer Science+Business Media New York. The Fas receptor (FasR)/Fas ligand (FasL) system plays a significant role in the process of neuronal loss in neurological disorders. Thus, in the present study, we used a real-time PCR array focused apoptosis (Mouse Apoptosis RT2 PCR Array) to study the role of the Fas pathway in the apoptotic process that occurs in a kainic acid (KA) mice experimental model. In fact, significant changes in the transcriptional activity of a total of 23 genes were found in the hippocampus of wild-type C57BL/6 mice after 12 h of KA treatment compared to untreated mice. Among the up-regulated genes, we found key factors involved in the extrinsic apoptotic pathway, such as tnf, fas and fasL, and also in caspase genes (caspase-4, caspase-8 and caspase-3). To discern the importance of the FasR/FasL pathway, mice lacking the functional Fas death receptor (lpr) were also treated with KA. After 24 h of neurotoxin treatment, lpr mice exhibited a reduced number of apoptotic positive cells, determined by the terminal deoxynucleotidyl transferase dUTP nick end labelling (TUNEL) method in different regions of the hippocampus, when compared to wild-type mice. In addition, treatment of lpr mice with KA did not produce significant changes in the transcriptional activity of genes related to apoptosis in the hippocampus, either in the fas and fas ligand genes or in caspase-4 and caspase-8 and the executioner caspase-3 genes, as occurred in wild-type C57BL/6 mice. Thus, these data provide direct evidence that Fas signalling plays a key role in the induction of apoptosis in the hippocampus following KA treatment, making the inhibition of the death receptor pathway a potentially suitable target for excitotoxicity neuroprotection in neurological conditions such as epilepsy.Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CiberNed-Instituto de Salud Carlos III) and by grants fromMinisterio de Ciencia (MICINN, MINECO) SAF2009-08233 and SAF2012-34177 and Fundación Ramón Areces to JJL. Grant 2009/SGR00853 from the Generalitat de Catalunya (Autonomous Government of Catalonia) and grants BFU2010-19119/BFI to CA, SAF2011-23631 to AC, and SAF2012-39852-C02-01 to MP from the Spanish Ministerio de Ciencia (MICINN, MINECO) also supported the study. Grant 0177594 from CONACYT (Mexico)Peer Reviewe
El proyecto de e-Administración de la UPC
Gener, David. El Proyecto de e-Administración en la UPC. [en línia]. 2011. [Consulta: 26 de Mayo de 2011]. Presentació a les XVII Jornadas de la Conferencia de Archiveros de Universidades, Universidad de Burgos, Burgos, 25 al 27 de Mayo de 2011.Postprint (author's final draft
Embryonic Neural Stem Cell Differentiation to Aldynoglia Induced by Olfactory Bulb Ensheathing Cell-Conditioned Medium
Although the relevance of glial cells in regulating brain activity was predicted by Ramon y
Cajal more than a century ago (García-Marín et al., 2007), it was not until almost fifty years
ago that initial descriptions of a close functional relationship between neuroglia and
neuronal perikarya (Hyden, 1962) or axonal processes (Blunt et al, 1965) began to reveal that
neurons and glial cells operate as functional units in the central nervous system (CNS).
However, this functional interaction has only been more carefully studied and analysed in
the last few decades, generating a substantial increase in research on the roles of neuron–
glia interactions in the control of brain function. Glial cells have subsequently been
implicated in many functions, including: guiding the migration of neurons in early
development, axonal guidance and being responsible for their integrity, forming the
necessary scaffold for neuronal architecture and neural protection and proliferation by
trophic effects, modulating neurodegenerative processes, and also being critical participants
in synaptic transmission, and key regulators of neurotransmitter release..
Examining Thermal Management Strategies for a Microcombustion Power Device
Microcombustion attracts interest with its promise of energy dense power generation for electronics. Yet, challenges remain to develop this technology further. Thermal management of heat losses is a known hurdle. Simultaneously, non-uniformities in heat release within the reaction regions also affect the device performance. Therefore a combination of thermal management strategies are necessary for further performance enhancements. Here, a bench top platinum nanoparticle based microcombustion reactor, coupled with thermoelectric generators is used. Methanol-air mixtures achieve room temperature ignition within a catalytic cartridge. In the current study, the reactor design is modified to incorporate two traditional thermal management strategies. By limiting enthalpic losses through the exhaust and reactor sides, using multi-pass preheating channels and heat recirculation, expected improvements are achieved. The combined strategies doubled the power output to 1.01 W when compared to the previous design. Furthermore, a preliminary study of catalyst distribution is presented to mitigate non-uniform catalytic activity within the substrate. To do this, tailored distribution of catalyst particles was investigated. This investigation shows a proof-of-concept to achieve localized control, thus management, over heat generation within substrates. By optimizing heat generation, a highly refined combustion-based portable power devices can be envisioned
Entorn de comunicació d'unitats d'informació social
Treballs Finals de Grau d'Enginyeria Informàtica, Facultat de Matemàtiques, Universitat de Barcelona, Any: 2015, Director: Sergio Escalera Guerrero i Marc OliuPodria començar fent la introducció del meu treball final de grau, exposant la idea que vol
transmetre, i sota la qual vaig decidir acceptar-lo i tirar-lo endavant: “compartir informació i coneixement és positiu i ens permet fer més amb menys”.
Aquesta idea, però, és tan àmplia que cal acotar-la i explicar quina és la situació sobre la qual
la treballarem. És aquí on pronunciem per primer cop Unitats d’Informació Social (UIS).
Les UIS són unitats reals o virtuals instrumentals dissenyades per a compartir informació en
l’àmbit social al voltant de dos blocs:
1. Les Bases de dades generals: socials, legals, de guies d’actuació, sanitàries, educatives..
2. La Base de dades de casos: Història Social del ciutadà o de la família.
En l’àmbit sociosanitari, podríem definir el servei d’atenció a les persones, les seves unitats
organitzatives i els seus professionals com a nodes, en un sistema en que les dades, la
informació i el coneixement són claus.
Dins d’aquest àmbit, els professionals són treballadors del coneixement, en organitzacions que
aprenen i canvien en un entorn en constant transformació i on les estratègies tradicionals es
veuen superades en el seu intent de respondre de forma eficient a les problemàtiques socials
actuals.
Comunicar aquests nodes per transmetre coneixement, ha de permetre una millora sota la
qual és possible resoldre una problemàtica de manera més beneficiosa.
El meu projecte es centra en fer possible aquesta comunicació
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