Structural Justice: A critical feminist framework exploring the intersection between justice, equity and structural reconciliation.

Violence against women is a human rights violation (UN, 2006). It affects the health of women globally (UN, 2009) and its elimination is at the heart of many international and national goals. Intimate partner violence (IPV), one of the most common forms of gender-based violence, affects one in three women worldwide (WHO, 2013). The consequences of IPV create negative health outcomes for women that diminish their quality of life and their overall well-being. Abused women access community supports such as shelters to seek safe refuge from the abuse and restore their lives. While shelters play an extensive role in helping women to rebuild their lives they often struggle to navigate inflexible and unjust systemic structures that can be re-victimizing to women and undermine their ability to live violence free. This study describes an emergent narrative of structural justice (SJ) that arose while examining the structural challenges of 6 shelters for abused women in urban and rural Virginia. It details the critical exploration of the intersection between structure and justice by integrating existing literature with qualitative participant narratives (N=36); and constructing an operational definition of structural justice (SJ) through an iterative process. Findings reveal SJ oriented patterns that shape five core tenets at the heart of this narrative. This SJ offers a framework out of which we can create a narrative of hope and a call-to-action. to rectify systemic violence. This framework contributes to the discourse concerning the elimination of VAW as it focuses on creating justice, equity and structural reconciliation

Web application of physiological data based on FHIR

This paper works toward implementing a prototype demonstrating some of the capabilities of the FHIR specification. The specification requires a clear understanding of its different components in order to be successfully implemented, therefore the primary concern of this work is to understand and analyse FHIR’s concepts. The research conducted in this work revealed that FHIR is a well-designed specification, based on a powerful data model and technologies. Therefore, it sould help solving the interoperability issues of the healthcare eco-system. It has also been pointed that since FHIR is a recent standard, many of its uses and benefits are still to be discovered. Moreover, FHIR integrates well in the current health information technology context since it can be used in addition to existing standards

BioModels Database: Next generation model repository

Public announce that the software system running BioModels Database ("http://www.ebi.ac.uk/biomodels/":http://www.ebi.ac.uk/biomodels/) will evolve from open source to a community developed project

Yes, Virginia, There Are Full-Text Articles in That Bound Periodical!: Helping Students Make Connections About Locating Journal Articles

The overall theme of the program concerns the methods of instruction librarians are using to teach basic information about the following: journal formats, such as current, bound, microfilm, and electronic; elements of journal citations, such as publication date, volume numbers, and issue numbers; and why it is essential for students to understand this information in order to locate articles in print and electronic formats. The presenters will discuss their experiences and active learning activities used to introduce journal formats, the elements of journal citations, and journal locator tools, such as EBSCO A to Z and SFX, during library instruction sessions. They will also discuss the results of a survey administered to instruction librarians in the southeast regarding the methods used in teaching the elements of a journal citation and how they are used in locating articles in the library and in full-text electronic databases. Finally, the presenters will initiate a discussion with the program attendees to share their experiences teaching patrons about journal formats, elements of journal citations, and journal locator tools

Clathrin Heavy Chain subunits coordinate endo- and exocytic traffic and affect stomatal movement

The current model for vesicular traffic to and from the plasma membrane is accepted but the molecular requirements for this coordination are not well defined. We have identified the has1 mutant, which has a stomatal function defect, as a clathrin heavy chain 1 (CHC1) mutant allele and show that it has a decreased rate of endocytosis and growth defects that are shared with other chc1 mutant alleles. We used chc1 alleles and the related chc2 mutant as tools to investigate the effects clathrin defects have on secretion pathways and plant growth. We show that secretion and endocytosis at the plasma membrane is sensitive to CHC1 and CHC2 function in seedling roots, and that chc mutants have physiological defects in stomatal function and plant growth that have not been previously described. These findings suggest that clathrin supports specific functions of multiple cell types. Stomata movement and gas exchange is altered in chc mutants, indicating clathrin is important for stomatal regulation. The aberrant function of chc mutant stomata is consistent with the growth phenotypes observed under different water and light conditions, which are also similar to those of the secretory SNARE mutant, syp121. The syp121 and chc mutants have impaired endo- and exocytosis compared to wild type, indicating a link between SYP121-dependent secretion and clathrin-dependent endocytosis at the plasma membrane. Our findings provide evidence that clathrin and SYP121 functions are important for the coordination of endo- and exocytosis, and have an impact on stomatal function, gas exchange, and vegetative growth in Arabidopsis

Biomarkers of coronary endothelial health: correlation with invasive measures of collateral function, flow and resistance in chronically occluded coronary arteries and the effect of recanalization

Objectives: In the presence of a chronically occluded coronary artery, the collateral circulation matures by a process of arteriogenesis; however, there is considerable variation between individuals in the functional capacity of that collateral network. This could be explained by differences in endothelial health and function. We aimed to examine the relationship between the functional extent of collateralization and levels of biomarkers that have been shown to relate to endothelial health. Methods: We measured four potential biomarkers of endothelial health in 34 patients with mature collateral networks who underwent a successful percutaneous coronary intervention (PCI) for a chronic total coronary occlusion (CTO) before PCI and 6-8 weeks after PCI, and examined the relationship of biomarker levels with physiological measures of collateralization. Results: We did not find a significant change in the systemic levels of sICAM-1, sE-selectin, microparticles or tissue factor 6-8 weeks after PCI. We did find an association between estimated retrograde collateral flow before CTO recanalization and lower levels of sICAM-1 (r=0.39, P=0.026), sE-selectin (r=0.48, P=0.005) and microparticles (r=0.38, P=0.03). Conclusion: Recanalization of a CTO and resultant regression of a mature collateral circulation do not alter systemic levels of sICAM-1, sE-selectin, microparticles or tissue factor. The identified relationship of retrograde collateral flow with sICAM-1, sE-selectin and microparticles is likely to represent an association with an ability to develop collaterals rather than their presence and extent