52 research outputs found
Atuação do bibliotecário na gestão da inovação
TCC (graduação) - Universidade Federal de Santa Catarina, Centro de Ciências da Educação, Curso de Biblioteconomia.A Gestão da Inovação é um processo de coleta e análise de informação com o propósito de garantir serviços e produtos inovadores para as organizações. Este processo engloba Gestão da Informação (GI), Gestão do Conhecimento (GC) e Inteligência Competitiva (IC). A presente pesquisa tem como objetivo estudar a participação do bibliotecário no processo de análise da Gestão da Inovação. Discorre sobre as atividades desenvolvidas pelo bibliotecário no contexto organizacional, utilizando os processos da GI, GC e IC. Trata-se de uma pesquisa exploratória, de abordagem qualitativa, utilizando procedimentos técnicos para um estudo de caso. A coleta de dados foi realizada por meio de entrevistas, com bibliotecários de Florianópolis. Os dados obtidos foram categorizados utilizando-se a técnica de análise de Laurence Bardin. A partir dos resultados obtidos foi possível conhecer o perfil dos bibliotecários, as funções que realizam, a participação dos mesmos na GI, GC e IC, a atuação do profissional na análise, o estímulo das organizações para criatividade e se as mesmas possuíam projetos inovadores. Constatou-se que os bibliotecários atuam na Gestão da Inovação por participar dos processos que envolvem GI, GC e IC, utilizando informações para gerar estratégia no meio organizacional. Constatou-se também, a atuação no processo de análise por parte dos profissionais, oferecendo a oportunidade de especializar-se ou buscar ajuda de especialistas na área para realizar a análise. Conclui-se que as empresas de Florianópolis incentivam a criatividade e possuem projetos inovadores, mas em alguns casos a cultura organizacional não permite que as inovações se desenvolvam, exigindo envolvimento da gerência com as atividades.The Innovation management is a process of collecting and analyzing information in order to ensure innovative products and services for organizations. This process includes Information Management (IM), Knowledge Management (KM) and Competitive Intelligence (CI). This research aims to study the role of the librarian in the process of Innovation Management analysis. Discusses the activities of the librarian in the organizational context, using the processes of the IM, KM and CI. This is an exploratory, qualitative approach, using technical procedures for a case study. Data collection was conducted through interviews with librarians from Florianópolis. The data were categorized using Laurence's Bardin analysis technique. From the results it was possible to know the profile of librarians, the functions they perform, their participation in IM, KM and CI, the performance of professional analysis, the encouraging of the organization for creativity and whether they had innovative designs. It was found that librarians working in Innovation Management by participating in processes involving IM, KM and CI using information to generate organizational strategy in the middle. It was also, in the performance analysis process by professionals, offering the opportunity to specialize or seek help from experts in the field to perform these analysis. We conclude that Florianópolis companies encourage creativity and innovative designs, but in some cases the organizational culture does not allow the innovatives to develop, requiring management professionals involvement in the activitie
Metodologia para avaliação do desempenho estrutural de pontes e viadutos e análise das patologias encontradas
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Positron Emission Tomography With 2-[18F]-Fluoro-2-Deoxy-D-Glucose For Initial Staging Of Hodgkin Lymphoma: A Single Center Experience In Brazil
BACKGROUND: 2-[18F]-Fluoro-2-Deoxy-D-Glucose (FDG-PET) is a well established functional imaging modality for the initial staging of Hodgkin lymphoma (HL) in patients from Western Europe and North America. The reliability of FDG-PET in populations of different ethnic groups is unclear, as all investigations published to date have come from developed countries. PURPOSE: The aim of the present study was to investigate the effectiveness of FDG-PET in the initial staging of HL patients in a Brazilian population. METHODS: Eighty-two patients with newly diagnosed HL were prospectively included in the study. All patients were staged with both conventional clinical staging (CCS) methods, including computed tomography (CT) and whole-body FDG-PET methods. A standard of reference for the nodal regions and the extranodal organs was determined using all available information, including the CCS methods, FDG-PET, the diagnostic histology and the follow-up examinations. The results of the CCS were then compared to the FDG-PET results. RESULTS: The sensitivity of FDG-PET was higher for nodal staging than that of CT (87.8% vs. 61.6%, respectively). FDG-PET was also more sensitive than CT in regard to evaluating the extranodal organs for lymphomatous involvement (96.2% vs. 40.0%, respectively). FDG-PET detected all 16 patients who were characterized by a positive bone marrow biopsy and identified an additional 4 patients with bone marrow disease. The incorporation of FDG-PET coupled with CCS in the staging procedure upstaged 20% (17/82) of the patients and downstaged 11% (9/82) of the patients. As a result of these changes in staging, 15% (13/82) of the patients would have received a different therapeutic regimen. CONCLUSIONS: The FDG-PET method is superior to CT for the detection of nodal and extra-nodal HL. The observation that the FDG-PET method upstaged the disease was the most common result (20% of patients) brought about by the addition of PET to the staging algorithm, even in a population of patients with a high incidence of advanced disease. However, changes in stages based on FDG-PET results should be confirmed by biopsy
Revisão sistemática do uso de fitobióticos na nutrição de frangos de corte
The objective of this study was to conduct a systematic review of the literature on the use of phytogenics in broiler nutrition. A bibliographic survey was conducted for the years between 2009 and 2019, using the keywords “eubiotics,” “phytobiotics,” “essential oils,” “phytogenic extracts,” and corresponding words associated with the terms “broiler” and “poultry.” The selected articles were grouped into the categories: animal performance, histomorphology of the intestinal wall, biochemical profile, carcass characteristics, and the effect on bacteria found in the intestine. After comparisons of several parameters on the use or non-use of phytogenics, it was found that replacing antibiotics with phytogenics contributes positively to performance, the histomorphology of the intestinal wall, the biochemical profile, carcass characteristics, and the number of bacteria found in the gut. In conclusion, based on several studies found in the literature, replacing antibiotics with phytogenic additives in broiler nutrition may be viable due to their lower residual impact on the final product, in addition to their positive effect on the parameters of animal production.Objetivou-se realizar uma revisão sistemática da literatura sobre o uso de fitogênicos na nutrição de frangos de corte. Foi realizado levantamento bibliográfico do período de 2009 a 2019. Foram utilizadas as palavras-chave utilizadas foram “eubióticos”, “fitobióticos”, “óleos essenciais” e “extratos fitogênicos” e suas correspondentes em inglês, “eubiotics” e “phytobiotics”, “essential oils” e “phytogenic extracts” associada a palavra “frango de corte”, e “poultry” em inglês. Os artigos selecionados foram agrupados nas categorias: desempenho zootécnico, histomorfologia da parede intestinal, perfil bioquímico do sangue, característica de carcaça e o efeito nas bactérias encontradas no intestino. Após comparações de diversos parâmetros sobre o uso ou não uso de fitogênicos, percebeu- se que a substituição dos antibióticos pelos fitogênicos pode ser considerado positiva para o desempenho, histomorfologia da parede intestinal, perfil bioquímico do sangue, característica de carcaça e número de bactérias encontradas no intestino. Sendo assim, foi concluído com base nos diversos trabalhos encontrados na literatura que a substituição dos antibióticos pelos aditivos fitogênicos na nutrição de frangos de corte pode ser viável, devido ao seu menor impacto residual no produto final, além de influenciar positivamente nos parâmetros de produção animal
Schinus molle: anatomy of leaves and stems, chemical composition and insecticidal activities of volatile oil against bed bug (Cimex lectularius)
© 2019 by the authors The investigation of the constituents that were isolated from Turnera diffusa (damiana) for their inhibitory activities against recombinant human monoamine oxidases (MAO-A and MAO-B) in vitro identified acacetin 7-methyl ether as a potent selective inhibitor of MAO-B (IC50 = 198 nM). Acacetin 7-methyl ether (also known as 5-hydroxy-40, 7-dimethoxyflavone) is a naturally occurring flavone that is present in many plants and vegetables. Acacetin 7-methyl ether was four-fold less potent as an inhibitor of MAO-B when compared to acacetin (IC50 = 50 nM). However, acacetin 7-methyl ether was \u3e500-fold selective against MAO-B over MAO-A as compared to only two-fold selectivity shown by acacetin. Even though the IC50 for inhibition of MAO-B by acacetin 7-methyl ether was ~four-fold higher than that of the standard drug deprenyl (i.e., SelegilineTM or ZelaparTM, a selective MAO-B inhibitor), acacetin 7-methyl ether’s selectivity for MAO-B over MAO-A inhibition was greater than that of deprenyl (\u3e500- vs. 450-fold). The binding of acacetin 7-methyl ether to MAO-B was reversible and time-independent, as revealed by enzyme-inhibitor complex equilibrium dialysis assays. The investigation on the enzyme inhibition-kinetics analysis with varying concentrations of acacetin 7-methyl ether and the substrate (kynuramine) suggested a competitive mechanism of inhibition of MAO-B by acacetin 7-methyl ether with Ki value of 45 nM. The docking scores and binding-free energies of acacetin 7-methyl ether to the X-ray crystal structures of MAO-A and MAO-B confirmed the selectivity of binding of this molecule to MAO-B over MAO-A. In addition, molecular dynamics results also revealed that acacetin 7-methyl ether formed a stable and strong complex with MAO-B. The selective inhibition of MAO-B suggests further investigations on acacetin 7-methyl as a potential new drug lead for the treatment of neurodegenerative disorders, including Parkinson’s disease
Calcium and Magnesium Ratio in Alfalfa Cultivation / Proporção Cálcio e Magnésio no Cultivo de Alfafa
The Alfalfa is an important forage for animal feeding, used in breeding of specialized herds due to its high protein content, besides having high palatability and energy value. In this context, the objective of this study was to evaluate the effect of calcium and magnesium ratio in the correction of Oxisol for the cultivation of alfalfa (Medicago sativa L.) cv. Creole. The experiment was conducted in the greenhouse at Federal University of Mato Grosso, Campus Rondonópolis-MT. The experimental design was completely randomized with nine treatments relating about calcium/magnesium nutrients: 0/0; 1/0; 0/1; 3/1; 6/1; 9/1; 12/1; 15/1 and 18/1, with 5 repetitions. The evaluated variables were plant height, number of leaves, number of basal shoots, SPAD index, stem diameter, fresh and shoot dry mass, root dry mass and root volume, soil pHCaCl2 and water use efficiency. The results were submitted to analysis of variance and Scott-knott test (p ≤ 0.05). Both the first and second cut, plant height was lower (24.76 ± 2.57 and 32.82 ± 13.01 cm, respectively) in absence of fertilizers (0/0) in relation to the other ratios. However, the treatments with Ca and/or Mg did not vary significantly, with a mean of 38.07 ± 2.94 and 51.73 ± 7.43 cm, in the first and second cut, respectively. The shoot dry mass showed similar behavior. Lower mass was observed in absence of Ca/Mg in the first cut (1.12 g DM pot-1) and second cut (1.84 g DM pot-1). In the other relations, it was observed a mean of 2.90 and 4.79 g DM pot-1 between the cuts. Likewise, the production of root was lower in absence of fertilizers (1.66 ± 1.05 g DM pot-1) and the others Ca/Mg ratios did not differ from each other (6.14 ± 1.98 g DM pot-1). The SPAD index there was significant effect only in the first cut between the ratio 0/0 and the others, with a mean of 43.48 ± 2.83 and 48.85 ± 2.19, respectively. In the second cut, SPAD index was 38.47 ± 5.82. Soil pH ranged from 5.87 to 5.31 between the cuts. Alfalfa was low sensitive to calcium and magnesium ratios in soil correction, but responded positively to the plant development with increased base saturation
Levantamento sobre vivências de violência entre estudantes de escolas públicas
Introduction: School violence it’s a problem that involves a lot of bad consequences for the life’s students. So preventing and research about it are very important.
Objective: The objective of this study was identify the experiences of violence of students from public schools participating in the PSE - School Health Program and SPE - Health and Prevention in the Schools of Florianópolis.
Methods: Participants were 871 students from the 9th grade of elementary school to the 3rd year of high school with a mean age of 15 years and 6 months.
Results: Regarding the experiences of violence, 81.6% stated that they had already witnessed scenes of violence, with 51.1% of these scenes occurring at school. Besides, 28% of the participants reported having already suffered prejudice at school. There was a statistically significant association between violent behavior and being a boy, having a habit of watching movies and playing video games with violent content, killing classes and having a regular to bad relationship with teachers.
Conclusions: Violence is part of student’s daily activities, involving a broad context and it is pretty much related to school.Introdução: A violência escolar é um problema que envolve muitas consequências ruins para a vida dos alunos Portanto, prevenir e pesquisar sobre isso é muito importante.
Objetivo: Identificar as experiências de violência de alunos de escolas públicas participantes do PSE - Programa de Saúde na Escola e SPE - Saúde e Prevenção nas Escolas de Florianópolis.
Métodos: Participaram 871 alunos da 9ª série do ensino fundamental ao 3º ano do ensino médio, com média de idade de 15 anos e 6 meses.
Resultados: Em relação às experiências de violência, 81,6% afirmaram já ter presenciado cenas de violência, sendo 51,1% delas na escola. Além disso, 28% dos participantes relataram já ter sofrido preconceito na escola. Houve associação estatisticamente significante entre comportamento violento e ser menino, com o hábito de assistir filmes e jogar videogame com conteúdo violento, matar aulas e ter um relacionamento regular a ruim com os professores.
Conclusões: A violência faz parte das atividades diárias do aluno, envolvendo um contexto amplo e está praticamente relacionada à escola
Impact of COVID-19 on cardiovascular testing in the United States versus the rest of the world
Objectives: This study sought to quantify and compare the decline in volumes of cardiovascular procedures between the United States and non-US institutions during the early phase of the coronavirus disease-2019 (COVID-19) pandemic.
Background: The COVID-19 pandemic has disrupted the care of many non-COVID-19 illnesses. Reductions in diagnostic cardiovascular testing around the world have led to concerns over the implications of reduced testing for cardiovascular disease (CVD) morbidity and mortality.
Methods: Data were submitted to the INCAPS-COVID (International Atomic Energy Agency Non-Invasive Cardiology Protocols Study of COVID-19), a multinational registry comprising 909 institutions in 108 countries (including 155 facilities in 40 U.S. states), assessing the impact of the COVID-19 pandemic on volumes of diagnostic cardiovascular procedures. Data were obtained for April 2020 and compared with volumes of baseline procedures from March 2019. We compared laboratory characteristics, practices, and procedure volumes between U.S. and non-U.S. facilities and between U.S. geographic regions and identified factors associated with volume reduction in the United States.
Results: Reductions in the volumes of procedures in the United States were similar to those in non-U.S. facilities (68% vs. 63%, respectively; p = 0.237), although U.S. facilities reported greater reductions in invasive coronary angiography (69% vs. 53%, respectively; p < 0.001). Significantly more U.S. facilities reported increased use of telehealth and patient screening measures than non-U.S. facilities, such as temperature checks, symptom screenings, and COVID-19 testing. Reductions in volumes of procedures differed between U.S. regions, with larger declines observed in the Northeast (76%) and Midwest (74%) than in the South (62%) and West (44%). Prevalence of COVID-19, staff redeployments, outpatient centers, and urban centers were associated with greater reductions in volume in U.S. facilities in a multivariable analysis.
Conclusions: We observed marked reductions in U.S. cardiovascular testing in the early phase of the pandemic and significant variability between U.S. regions. The association between reductions of volumes and COVID-19 prevalence in the United States highlighted the need for proactive efforts to maintain access to cardiovascular testing in areas most affected by outbreaks of COVID-19 infection
Estudo das propriedades mecânicas de concretos auto-adensáveis constituídos por diferentes materiais finos
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