Esportes radicais no meio ambiente urbano no município de São Paulo

The observation of people looking for squares, streets, climbing walls, benches, walls and ramps around the city to have fun and exercise represents a new context of sports practice that this research seeks to reveal. The objective of this study was to recognize the places and actors of skateboarding, climbing and slakline practices and their motivations for the search of these sports. Exploratory descriptive research was used with 46 subjects, 16 climbers, 20 skaters and 10 slakliners, from the city of São Paulo, who answered a questionnaire developed specifically for these activities. The results showed that: There is predominance of males among the participants, showing a prejudice that still persists in sports practice. Climbers have a higher average age than others, perhaps due to the need for more expensive equipment, greater risks of practice and the need for courses to learn. Skaters on average have been practicing for more time, probably because the skate culture is older and consolidated in São Paulo. It is observed that in slakline all practice less than three years showing that it is a modality still recent in the national scenario. The participants of the research affirm to have learned alone, or with friends and family, evidencing in this aspect that the Physical Education is not considered like initiation. The subjects point out the gain of physical, mental and social benefits in their lives and their intention to continue the practice by quality of life, fun, physical and psychological evolution. Only 10.8% claim to compete, which shows that Extreme Sports are considered from the perspective of voluntary participation. It is concluded that Extreme Sports are being incorporated into the routine of the people, adding a new contour to the body culture, in a search for overcoming, facing challenges, control of risk, pleasure, and quality of life. There is evidence that there is a gap between the graduation in Physical Education professionals and these new practices

Photobiomodulation reduces the cytokine storm syndrome associated with Covid-19 in the zebrafish model

Although the exact mechanism of the pathogenesis of COVID-19 is not fully understood, oxidative stress and the release of pro-inflammatory cytokines have been highlighted as playing a vital role in the pathogenesis of the disease. In this sense, alternative treatments are needed to reduce the inflammation caused by COVID-19. Therefore, this study aimed to investigate the potential effect of red PBM as an attractive therapy to downregulate the cytokine storm caused by COVID-19 from a zebrafish model. RT-PCR analyses and protein-protein interaction prediction among SARS-CoV-2 and Danio rerio proteins showed that rSpike was responsible for generating systemic inflammatory processes with significantly increased pro-inflammatory (il1b, il6, tnfa, and nfkbiab), oxidative stress (romo1) and energy metabolism (slc2a1a, coa1) mRNA markers, with a pattern like those observed in COVID-19 cases in humans. On the other hand, PBM treatment decreased the mRNA levels of these pro-inflammatory and oxidative stress markers compared with rSpike in various tissues, promoting an anti-inflammatory response. Conversely, PBM promotes cellular and tissue repair of injured tissues and significantly increases the survival rate of rSpike-inoculated individuals. Additionally, metabolomics analysis showed that the most impacted metabolic pathways between PBM and the rSpike-treated groups were related to steroid metabolism, immune system, and lipids metabolism. Together, our findings suggest that the inflammatory process is an incisive feature of COVID-19, and red PBM can be used as a novel therapeutic agent for COVID-19 by regulating the inflammatory response. Nevertheless, the need for more clinical trials remains, and there is a significant gap to overcome before clinical trials.publishedVersio

Análise comparativa da avaliação cognitivo-linguística em escolares ouvintes e usuário de implante coclear

RESUMO Objetivo Analisar e comparar o desempenho cognitivo-linguístico de uma criança usuária de implante coclear em relação aos seus pares ouvintes em processo de aprendizagem da leitura e da escrita. Método A amostra foi constituída por 11 crianças (na faixa etária de 7 a 10 anos de idade) ouvintes e uma usuária de implante coclear na orelha direita, matriculadas no 3º ano do ensino fundamental. O instrumento de avaliação utilizado foi o Protocolo de Avaliação das Habilidades Cognitivo-linguísticas. Os dados referentes às crianças foram transcritos e analisados utilizando-se a estatística descritiva. Resultados Os subtestes que apresentaram o maior percentual de crianças com desempenho superior foram: alfabeto em sequência (82%); leitura de pseudopalavras (82%); segmentação silábica (73%); repetição de palavras (82%); cópia de formas (72%); nomeação rápida (100%). Desses subtestes, a criança usuária de implante coclear apresentou desempenho superior em todos, exceto o de repetição de palavras, em que obteve desempenho médio. No subteste de ritmo, nenhuma criança obteve desempenho superior e a usuária de implante coclear obteve desempenho inferior. Conclusão A criança usuária de implante coclear apresentou um perfil cognitivo-linguístico bastante semelhante ao dos seus pares ouvintes. Ao que parece, as dificuldades de realização de algumas tarefas cognitivo-linguísticas estão relacionadas a fatores que vão além da integridade auditiva, haja vista que, em alguns subtestes, crianças ouvintes, obtiveram desempenho abaixo do esperado

Esportes radicais no meio ambiente urbano no município de São Paulo

The observation of people looking for squares, streets, climbing walls, benches, walls and ramps around the city to have fun and exercise represents a new context of sports practice that this research seeks to reveal. The objective of this study was to recognize the places and actors of skateboarding, climbing and slackline practices and their motivations for the search of these sports. Exploratory descriptive research was used with 46 subjects, 16 climbers, 20 skaters and 10 slackliners, from the city of São Paulo, who answered a questionnaire developed specifically for these activities. The results showed that: There is predominance of males among the participants, showing a prejudice that still persists in sports practice. Climbers have a higher average age than others, perhaps due to the need for more expensive equipment, greater risks of practice and the need for courses to learn. Skaters on average have been practicing for more time, probably because the skate culture is older and consolidated in São Paulo. It is observed that in slackline all practice less than three years showing that it is a modality still recent in the national scenario. The participants of the research affirm to have learned alone, or with friends and family, evidencing in this aspect that the Physical Education is not considered like initiation. The subjects point out the gain of physical, mental and social benefits in their lives and their intention to continue the practice by quality of life, fun, physical and psychological evolution. Only 10.8% claim to compete, which shows that Extreme Sports are considered from the perspective of voluntary participation. It is concluded that Extreme Sports are being incorporated into the routine of the people, adding a new contour to the body culture, in a search for overcoming, facing challenges, control of risk, pleasure, and quality of life. There is evidence that there is a gap between the graduation in Physical Education professionals and these new practices.A observação de pessoas procurando praças, ruas, paredes de escalada, bancos, muros e rampas pela cidade, para se divertir e se exercitar representa um novo contexto de prática esportiva que esta pesquisa busca revelar. O objetivo deste estudo foi reconhecer os locais e atores das práticas de skate, escalada e slakline e suas motivações para a busca destas modalidades. Utilizou-se uma pesquisa descritiva exploratória com 46 sujeitos, sendo 16 escaladores, 20 skatistas e 10 slakliners, da cidade de São Paulo, que responderam um questionário desenvolvido especificamente para essas atividades. Os resultados apontaram que: Há predominância do sexo masculino entre os participantes, revelando um preconceito que ainda perdura na prática esportiva. Os escaladores têm média de idade maior do que os demais, talvez devido à necessidade de equipamentos mais caros, dos maiores riscos da prática e da necessidade de cursos para aprendizagem. Os skatistas em média praticam há mais tempo, provavelmente porque a cultura do skate é mais antiga e consolidada em São Paulo. Observa-se que no slakline todos praticam a menos de três anos mostrando que é uma modalidade ainda recente no cenário nacional. Os participantes da pesquisa afirmam ter aprendido sozinhos, ou com amigos e familiares, evidenciando-se nesse aspecto que a Educação Física não é considerada como iniciação. Os sujeitos apontam o ganho de benefícios físicos, mentais e sociais nas suas vidas e sua intenção de continuar a prática pela qualidade de vida, diversão, evolução física e psicológica. Apenas 10,8% afirmam competir, o que mostra que os esportes radicais são considerados na perspectiva da participação voluntária. Conclui-se que os esportes radicais estão sendo incorporados à rotina das pessoas, acrescentando novo contorno à cultura corporal, numa busca de superação, de enfrentamento de desafios, do controle do risco, do prazer, e da qualidade de vida. Fica evidente que há uma distância entre a formação dos profissionais de Educação Física e estas novas práticas