Density-induced BCS to Bose-Einstein crossover

We investigate the zero-temperature BCS to Bose-Einstein crossover at the mean-field level, by driving it with the attractive potential and the particle density. We emphasize specifically the role played by the particle density in this crossover. Three different interparticle potentials are considered for the continuum model in three spatial dimensions, while both s- and d-wave solutions are analyzed for the attractive ~extended! Hubbard model on a two-dimensional square lattice. For this model the peculiar behavior of the crossover for the d-wave solution is discussed. In particular, in the strong-coupling limit when approaching half-filling we evidence the occurrence of strong correlations among antiparallel-spin fermions belonging to different composite bosons, which give rise to a quasi-long-range antiferromagnetic order in this limit

Chronic NSAIDs Therapy and Upper Gastrointestinal Tract – Mechanism of Injury, Mucosal Defense, Risk Factors for Complication Development and Clinical Management

Non steroidal anti-inflammatory drugs (NSAIDs) are the most prescribed medications worldwide because of their analgesic and anti-inflammatory properties. In fact, NSAIDs are generally prescribed for pain management in musculoskeletal or osteoarticolar pathologies and for rheumatic diseases, very common diseases in the general population. About twenty million US patients were prescribed NSAIDs every year. Although NSAIDs are generally well tolerated, chronic therapy is responsible for a significant morbidity and mortality rate; in fact, the incidence of GI events is significantly higher (about four fold) in patients receiving NSAIDs chronic therapy. Adverse gastrointestinal events related to NSAIDs therapy occur in a little but significant amount of patients, resulting in an important morbidity and mortality. In the US more than 150 per 100.000 patients were admitted every year for NSAIDs related adverse events, resulting in about 15000 deaths. The chapter covers the mechanism of NSAIDs related injury, mucosal defense, risk factors for complication development and the clinical management

A comparison of a SARS-CoV-2 rapid-test and serological-test in a Public Health Hospital

Nowadays, with the start of the vaccination campaign is very important to assess the extent of exposure of the population and identifying rapid, sensitive and accurate test to quickly identify new cases of SARS-CoV-2. The rapid test, cheap and easy to perform, is therefore very useful in developing countries, where the vaccination campaign has not yet reached adequate coverage

A description logic based approach for matching user profiles

Several applications require the matching of user profiles, e.g., job recruitment or dating systems. In this paper we present a logical framework for specifying user profiles that allows profile description to be incomplete in the parts that are unavailable or are considered irrelevant by the user. We present an algorithm for matching demands and supplies of profiles, taking into account incompleteness of profiles and incompatibility between demand and supply. We specialize our framework to dating services; however, the same techniques can be directly applied to several other contexts

Microwave Ablation in Intermediate Hepatocellular Carcinoma in Cirrhosis: An Italian Multicenter Prospective Study

Background and Aims: To report long-term results in treatment of intermediate hepatocellular carcinoma (HCC) in cirrhotics using new high-powered microwaves (MWS) ablation alone. Methods: This multicenter study included 215 cirrhotics (age range: 67-84 years; 137 males; 149 Child A, 66 Child B) who underwent percutaneous ultrasound-guided high-powered MWS ablation instead of transarterial chemoembolization. Among the patient population, 109 had a single nodule (Ø 5.3-8 cm) [group A], 70 had 2 nodules (Ø 3-6 cm) [group B] and 36 had 3-5 nodules (Ø 1.5-6.8 cm) [group C]. MWS ablation efficacy was evaluated using enhanced-computed tomography and/or magnetic resonance imaging. Primary end-point was 5-year cumulative overall survival (OS). Results: On enhanced-computed tomography and/or magnetic resonance imaging, complete ablation rates were 100% for 1.5-3.5 cm nodules. In nodules >3.5-5 cm, it was 89% for the first ablation and 100% for the second. For lesions >5-8 cm, ablation was up to 92%. Overall, 1-, 3- and 5-year survival rates were 89, 60, and 21%, respectively. The cumulative OS rate of group A was 89%, 66% and 34% at 1, 3 and 5 years. The cumulative OS rate of group B was 88%, 60% and 11% at 1, 3 and 5 years. The cumulative OS rate of group C was 86%, 55% and 0%. The 5-year survival rate was significantly different among the groups (p <0.001). One patient died from rupture of HCC. Upon multivariate analysis, preablation total bilirubin >1.5 mg/dL was an independent factor for predicting lower survival. Conclusions: Percutaneous MWS ablation of intermediate HCC is safe and effective in inducing large volume of necrosis in intermediate HCC nodules, providing long-term survival rates similar to transarterial chemoembolization. Preablation total bilirubin >1.5 mg/dL as expression of liver function reserve is the main factor predicting a worse outcome

Augmented Business Process Management Systems: A Research Manifesto

Augmented Business Process Management Systems (ABPMSs) are an emerging class of process-aware information systems that draws upon trustworthy AI technology. An ABPMS enhances the execution of business processes with the aim of making these processes more adaptable, proactive, explainable, and context-sensitive. This manifesto presents a vision for ABPMSs and discusses research challenges that need to be surmounted to realize this vision. To this end, we define the concept of ABPMS, we outline the lifecycle of processes within an ABPMS, we discuss core characteristics of an ABPMS, and we derive a set of challenges to realize systems with these characteristics.Comment: 19 pages, 1 figur

AI-augmented business process management systems: a research manifesto

AI-augmented Business Process Management Systems (ABPMSs) are an emerging class of process-aware information systems, empowered by trustworthy AI technology. An ABPMS enhances the execution of business processes with the aim of making these processes more adaptable, proactive, explainable, and context-sensitive. This manifesto presents a vision for ABPMSs and discusses research challenges that need to be surmounted to realize this vision. To this end, we define the concept of ABPMS, we outline the lifecycle of processes within an ABPMS, we discuss core characteristics of an ABPMS, and we derive a set of challenges to realize systems with these characteristics

Six-month psychophysical evaluation of olfactory dysfunction in patients with COVID-19

This study prospectively assessed the six-month prevalence of self-reported and psychophysically measured olfactory dysfunction in subjects with mild-to-moderate COVID-19. Self-reported smell or taste impairment was prospectively evaluated by SNOT-22 at diagnosis, 4-week, 8-week, and 6-month. At 6 months from the diagnosis, psychophysical evaluation of olfactory function was also performed using the 34-item culturally adapted University of Pennsylvania Smell Identification Test (CA-UPSIT). 145 completed both the 6-month subjective and psychophysical olfactory evaluation. According to CA-UPSIT, 87 subjects (60.0%) exhibited some smell dysfunction, with 10 patients being anosmic (6.9%) and 7 being severely microsmic (4.8%). At the time CA-UPSIT was administered, a weak correlation was observed between the self-reported alteration of sense of smell or taste and olfactory test scores (Spearman's r=-0.26). Among 112 patients who self-reported normal sense of smell at last follow-up, CA-UPSIT revealed normal smell in 46 (41.1%), mild microsmia in 46 (41.1%), moderate microsmia in 11 (9.8%), severe microsmia in 3 (2.3%), and anosmia in 6 (5.4%) patients; however, of those patients self-reporting normal smell but who were found to have hypofunction on testing, 62 out of 66 had self-reported reduction in sense of smell or taste at an earlier time point. Despite most patients report a subjectively normal sense of smell, we observed a high percentage of persistent smell dysfunction at 6 months from the diagnosis of SARS-CoV-2 infection, with 11.7% of patients being anosmic or severely microsmic. These data highlight a significant long-term rate of smell alteration in patients with previous SARS-COV-2 infection