54 research outputs found
Determination of the LOQ in real-time PCR by receiver operating characteristic curve analysis: application to qPCR assays for Fusarium verticillioides and F. proliferatum
- Author
- A Bottalico
- A Logrieco
- A Logrieco
- A Srobarova
- A Yiannikouris
- AE Desjardins
- AE Desjardins
- B Patino
- C Brandfass
- CW Bacon
- E Moeller
- G Mule
- G Munkvold
- GS Shephard
- H Abbas
- H Schaefer
- HHL Gonzalez
- I Murillo
- I Visentin
- I Zimmer
- J D’Mello
- J Leslie
- J Rheeder
- JF Leslie
- Katharina Döll
- M Greiner
- M Jestoi
- M Jurado
- M Pascale
- M Ramirez
- MF Dutton
- P Nicholson
- P Thiel
- Petr Karlovsky
- R Fluss
- R Haeckel
- R Kaus
- S Chulze
- S Yazar
- Sabine Nutz
- SN Chulze
- SR Mikkelsen
- T Adejumo
- T Adejumo
- T Miedaner
- WW Turechek
- Publication venue
- Springer-Verlag
- Publication date
- 01/01/2011
- Field of study
Real-time PCR (qPCR) is the principal technique for the quantification of pathogen biomass in host tissue, yet no generic methods exist for the determination of the limit of quantification (LOQ) and the limit of detection (LOD) in qPCR. We suggest using the Youden index in the context of the receiver operating characteristic (ROC) curve analysis for this purpose. The LOQ was defined as the amount of target DNA that maximizes the sum of sensitivity and specificity. The LOD was defined as the lowest amount of target DNA that was amplified with a false-negative rate below a given threshold. We applied this concept to qPCR assays for Fusarium verticillioides and Fusarium proliferatum DNA in maize kernels. Spiked matrix and field samples characterized by melting curve analysis of PCR products were used as the source of true positives and true negatives. On the basis of the analysis of sensitivity and specificity of the assays, we estimated the LOQ values as 0.11 pg of DNA for spiked matrix and 0.62 pg of DNA for field samples for F. verticillioides. The LOQ values for F. proliferatum were 0.03 pg for spiked matrix and 0.24 pg for field samples. The mean LOQ values correspond to approximately eight genomes for F. verticillioides and three genomes for F. proliferatum. We demonstrated that the ROC analysis concept, developed for qualitative diagnostics, can be used for the determination of performance parameters of quantitative PCR
Identification of Amazonian Trees with DNA Barcodes
- Author
- A Balmford
- A Chanderbali
- A Valentini
- AH Gentry
- AJ Fazekas
- Andy Hector
- Aurélien Roger
- Bernard Riéra
- C Moritz
- Christophe Thébaud
- Christopher Baraloto
- CS Ford
- CV De Castilho
- CW Dick
- DP Little
- DS Devey
- EA Friar
- H ter Steege
- H Tuomisto
- HP Linder
- J Pons
- J Shaw
- JA Jurado-Riviera
- JE Richardson
- JF Starr
- Julien Engel
- Jérôme Chave
- K Munch
- K Tamura
- KressWJ
- M Anisimova
- M Blaxter
- M Elias
- M Kimura
- M Margulies
- M Ronaghi
- M-F Deguilloux
- MA Larkin
- Mailyn Adriana Gonzalez
- MJ Hickerson
- ML Hollingsworth
- MW Chase
- MW Chase
- MW Chase
- N Smith
- NCA Pitman
- NCA Pitman
- P Taberlet
- Pascal Pétronelli
- PD Coley
- PDN Hebert
- PDN Hebert
- R Condit
- R Floyd
- R Lahaye
- R Meier
- RJ Petit
- S Guindon
- SA Mori
- SA Mori
- SA Smith
- Scott A. Mori
- SG Newmaster
- SP Hubbell
- TLP Couvreur
- TM Brooks
- U Swenson
- V Savolainen
- WF Laurance
- WJ Kress
- WJ Kress
- Y Malhi
- Z Abdo
- Publication venue
- Public Library of Science
- Publication date
- 01/01/2009
- Field of study
International audienc
Rootless tephra stratigraphy and emplacement processes
- Author
- A Belousov
- B Zimanowski
- Christopher W. Hamilton
- CI Schipper
- CJ Hickson
- CW Hamilton
- CW Hamilton
- CW Hamilton
- DM Pyle
- DS Drumheller
- Erin P. Fitch
- GPL Walker
- H Frey
- H Frey
- H-U Schmincke
- J Sinton
- JDL White
- JDL White
- K Hon
- K Wohletz
- K Wohletz
- K Wohletz
- KH Wohletz
- KH Wohletz
- MF Sheridan
- MJ Rossi
- MJ Rossi
- MM Morrissey
- MT Guðmundsson
- PD Lanagan
- R Büttner
- R Greeley
- RD Terry
- RG Andrews
- RV Fisher
- S Thorarinsson
- S Thorarinsson
- SA Colgate
- SA Fagents
- Sarah A. Fagents
- SJ Blott
- T Thordarson
- Thorvaldur Thordarson
- TN Mattox
- V Lorenz
- V Lorenz
- Z Jurado-Chichay
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Rootless cone eruption processes informed by dissected tephra deposits and conduits
- Author
- B Zimanowski
- BC Bruno
- BF Houghton
- BP Kokelaar
- CE Parcheta
- CJ Busby-Spera
- CW Hamilton
- CW Hamilton
- CW Hamilton
- CW Hamilton
- D Swanson
- DA Swanson
- E. W. Llewellin
- FC Ramos
- GA Smith
- GA Valentine
- GPL Walker
- GPL Walker
- H-U Schminke
- IP Skilling
- J Wolff
- JA Hooten
- JDL White
- K Hon
- K Simpson
- K. Fielding
- L Melchior Larsen
- LP Keszthelyi
- LP Keszthelyi
- MJ Rossi
- P. Reynolds
- PD Lanagan
- PE Long
- R Büttner
- R Greeley
- R. J. Brown
- RA Duraiswami
- RJ Brown
- RV Fisher
- S Self
- S Thorarinsson
- S Thorarinsson
- SA Fagents
- SH Jafri
- SP Reidel
- SP Reidel
- T Thordarson
- T Thordarson
- T Thordarson
- T. Thordarson
- TN Mattox
- VE Camp
- WB Bryan
- WL Jaeger
- Y Goto
- YK Sohn
- Z Jurado-Chichay
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
AMPK in Pathogens
- Author
- A Acosta-Serrano
- A Barquilla
- A Barquilla
- A Bonen
- A Crawford
- A Schubert-Unkmeir
- A Singhal
- A Street
- A Woods
- A Woods
- AC Ferretti
- AJ Hoogendijk
- AK Pandey
- AS Marsin
- B Hurtrel
- B Kelly
- B Levine
- B Sampaio-Marques
- B Xiao
- BF Holmes
- BM Mony
- BM Mony
- C Bermejo
- C Hutterer
- C Polge
- CB Ramsook
- CE Moseley
- CM Hull
- CS Clemmens
- CS Yang
- CW Ong
- CY Park
- D Bumann
- D Ghosh
- D Kumar
- D Miranda-Saavedra
- D Moreira
- D Sag
- D Yang
- DA Escobar
- DE Levin
- DF Egan
- DG Hardie
- DG Hardie
- DM Shin
- DW Park
- E Gjini
- E Rey-Jurado
- E Vassella
- EB Gordon
- EJ Munoz-Elias
- EM Al-Olayan
- F Estruch
- F Nagajyothi
- F Navarro-Garcia
- F Rousset
- G Hu
- G Lv
- G Zandbergen van
- G Zhou
- GP Meares
- H Huang
- H Zangger
- H Zhao
- HC Ng
- HC Ng
- HJ Flint
- HS Kwon
- HS Zhang
- HS Zhang
- I Rabhi
- I Tattoli
- J Blagih
- J Blagih
- J Brunton
- J Daniel
- J Daniel
- J Estaquier
- J Estaquier
- J Estaquier
- J Kim
- J Kim
- J Mankouri
- J McArdle
- J McArdle
- J Rolf
- J Yang
- J Yang
- JC Ameisen
- JD Artz
- JD Burke
- JD McKinney
- JI MacRae
- JJ Kim
- JL Celenza
- JL Celenza
- JL Celenza
- JM Brenchley
- JM Gancedo
- JM Yuk
- JR Forbes
- JV Li
- JW Yu
- JY Seo
- K Ashrafi
- K Barnes
- K Hedbacker
- K Inoki
- K Moreau
- K Nakashima
- K Tsoyi
- K Vickerman
- K Yang
- KL Buchanan
- KL Caradonna
- KM Jeong
- KY Kang
- KY Rhee
- L Campillo-Gimenez
- L Chantranupong
- L Francione
- LC Pollitt
- LG Tilney
- LJ Terry
- M Carlson
- M Cemma
- M Fulco
- M Parsons
- M Raffatellu
- M Romero-Gomez
- MA Horwitz
- MC Cumont
- MC Lorenz
- MI Hood
- MR Gonzalez
- MT Sorbara
- N Kloft
- NJ MacIver
- O Vincent
- P Sanz
- R Appelberg
- R Mehla
- R Petter
- R Petter
- R Plummer
- R Santarelli
- R Tewari
- RD Adam
- RJ Shaw
- S Chakrabarti
- S Hohmann
- S Horman
- S Kuchin
- S Pagans
- S Steele
- SA Hawley
- SA Hawley
- SB Kudchodkar
- SC Stein
- SE Reece
- SH Kumar
- SM Landfear
- SR Waterman
- T Naderer
- TG Mitchell
- TS Moser
- TS Moser
- V Bracchi
- V Cecchinato
- V Deretic
- V Monceaux
- W Lee
- WT Ji
- WW Winder
- Y Abu Kwaik
- Y Guo
- Y Tang
- Y Wang
- YW Kim
- Z Yang
- Z Zhang
- Z Zhao
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2016
- Field of study
During host–pathogen interactions, a complex web of events is crucial for the outcome of infection. Pathogen recognition triggers powerful cellular signaling events that is translated into the induction and maintenance of innate and adaptive host immunity against infection. In opposition, pathogens employ active mechanisms to manipulate host cell regulatory pathways toward their proliferation and survival. Among these, subversion of host cell energy metabolism by pathogens is currently recognized to play an important role in microbial growth and persistence. Extensive studies have documented the role of AMP-activated protein kinase (AMPK) signaling, a central cellular hub involved in the regulation of energy homeostasis, in host–pathogen interactions. Here, we highlight the most recent advances detailing how pathogens hijack cellular metabolism by suppressing or increasing the activity of the host energy sensor AMPK. We also address the role of lower eukaryote AMPK orthologues in the adaptive process to the host microenvironment and their contribution for pathogen survival, differentiation, and growth. Finally, we review the effects of pharmacological or genetic AMPK modulation on pathogen growth and persistence.CIHR -Canadian Institutes of Health Researc
A new approach for potential drug target discovery through in silico metabolic pathway analysis using Trypanosoma cruzi genome information
- Author
- Acosta H
- Adroher FJ
- Affranchino JL
- Ana Carolina Ramos Guimarães
- Atwood JA 3rd
- Barrett MP
- Beach DH
- Berriman M
- Beswick TC
- Bilate AM
- Brak K
- Bringaud F
- Bringaud F
- Buhaescu I
- Canepa GE
- Cannata JJ
- Cavazzuti A
- Cazzulo JJ
- Cazzulo JJ
- Chambers JW
- Concepción JL
- Cordeiro AT
- Coura JR
- Croft SL
- Cáceres AJ
- de Boiso JF
- de Souza W
- de Souza W
- de Souza W
- Dias JC
- Dixon H
- Dixon H
- Docampo R
- Docampo R
- Doyle PS
- Duschak VG
- El-Sayed NM
- Espinosa A
- Freitas RF
- Fricker SP
- Galarreta BC
- Galperin MY
- Guimarães AC
- Haemers T
- Hannaert V
- Heby O
- Hudock MP
- Hurtado-Guerrrero R
- Igoillo-Esteve M
- Jiménez-Jiménez J
- Juan SM
- Jurado LA
- Kanehisa M
- Karp PD
- Korn ED
- Korn ED
- Krauth-Siegel RL
- Laurent E Dardenne
- Lee SH
- Liendo A
- Liñares GE
- Lorente SO
- Magaraci F
- Marcelo Alves-Ferreira
- Marin-Neto JA
- Martyn DC
- Maugeri DA
- Maya JD
- Michels PA
- Mielniczki-Pereira AA
- Montalvetti A
- Moyersoen J
- Olivares-Illana V
- Olivares-Illana V
- Otto TD
- Paulino M
- Pereira CA
- Perez-Pineiro R
- Peña-Díaz J
- Pourshafie M
- Priscila Vanessa da Silva Zabala Capriles
- Pérez-Montfort R
- Racagni GE
- Reyes-Vivas H
- Roberts CW
- Rocha MO
- Rodríguez-Romero A
- Rogerson GW
- Sanz-Rodriguez CE
- Schmunis GA
- Sgraja T
- Silber AM
- Silber AM
- Stephens JL
- Stern AL
- Sylvester D
- Tarleton RL
- Taylor MB
- Tetaud E
- Tielens AG
- Trapani S
- Urbina JA
- Urbina JA
- Urbina JA
- Urbina JA
- Urbina JA
- van Hellemond JJ
- van Hellemond JJ
- van Weelden SW
- Von Brand T
- Wiemer EA
- Wiesner J
- Wim M Degrave
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- Field of study
Iron Behaving Badly: Inappropriate Iron Chelation as a Major Contributor to the Aetiology of Vascular and Other Progressive Inflammatory and Degenerative Diseases
- Author
- A Abbott
- A Abou-Raya
- A Aljandali
- A Ambesi-Impiombato
- A Aydin
- A Balcerczyk
- A Besarab
- A Brzezinski
- A Campbell
- A Carrillo-Vico
- A Cavalli
- A Chattopadhyay
- A Chattopadhyay
- A Cherubini
- A Dey
- A Doms
- A Donovan
- A Donovan
- A Dávalos
- A Gaeta
- A Garny
- A Gnjec
- A Gomes
- A Gopalakrishnan
- A Hald
- A Henney
- A Hirayama
- A Hoffmann
- A Huber
- A Hugman
- A Iannetti
- A Ide-Ektessabi
- A Jacobs
- A Jeyabalan
- A Kahvejian
- A Karrar
- A Kasztler
- A Kibel
- A Kocyigit
- A Kotha
- A Kumral
- A Lass
- A Lecube
- A Lewén
- A Lotery
- A Maggio
- A Malek
- A Malik
- A Mantovani
- A Matsuzawa
- A Mitra
- A Monge
- A Murakami
- A Murakami
- A Murakami
- A Murakami
- A Mutti
- A Nijnik
- A Nunomura
- A Nunomura
- A Patt
- A Persson
- A Pietrangelo
- A Piga
- A Pirat
- A Post
- A Pradhan
- A Protti
- A Rattner
- A Ravati
- A Rehman
- A Reynolds
- A Richmond
- A Roetto
- A Roetto
- A Rostom
- A Rumbold
- A Russo
- A Rötig
- A Saltelli
- A Saltelli
- A Sandek
- A Sassano
- A Scalbert
- A Scalbert
- A Scalbert
- A Sica
- A Smahi
- A Sola
- A Stintzi
- A Szewczyk
- A Taguchi
- A Tedgui
- A Terman
- A Terman
- A Terman
- A Undas
- A Virdis
- A Wagner
- A Wagner
- A Wagner
- A Wagner
- A Wojas-Pelc
- A Wong
- A Xu
- A Yoritaka
- A Yoshimura
- A-L Barabási
- AA Andreadis
- AA Borisy
- AA Farooqui
- AA Qutub
- AA Qutub
- AA Vlessis
- AB Nathens
- AB Parsons
- AB Parsons
- AB Thompson
- AB Thomson
- AC Bayne
- AC Bharti
- AC Cave
- AC Mello Filho
- AD d'Hardemare
- AD de Silva
- Ad hoc committee on systemic lupus erythematosus response criteria for fatigue
- ADL van der
- AE Aust
- AE Baue
- AE Finefrock
- AE Heazell
- AE Heazell
- AE Kartikasari
- AEC Ihekwaba
- AEC Ihekwaba
- AF Tramontano
- AH Berg
- AH Koeppen
- AH Koeppen
- AH Tong
- AI Bush
- AI Bush
- AI Bush
- AI Bush
- AI Faden
- AJ Ghio
- AJ Ghio
- AJ Ghio
- AJ Hulbert
- AJ Kowaltowski
- AJ Lusis
- AJ Matthews
- AJ Reyes
- AJ van Oostrom
- AJ Watson
- AJ White
- AJ Williams
- AK Junk
- AL Beal
- AL Hemdahl
- AL Hopkins
- AL Hopkins
- AL Lagan
- AL Mark
- AL Sirén
- AL Sirén
- AL Sirén
- AL Takeda
- AM Abeles
- AM Borzychowski
- AM Choi
- AM Dolga
- AM Elneihoum
- AM Elneihoum
- AM Feist
- AM Harvey
- AM Jenkinson
- AM Lin
- AM Samuni
- AM Snyder
- AN Crowson
- AN Tabah
- AP Bolger
- AP Breen
- AP Liappis
- AR Kallianpur
- AR Kallianpur
- AR Martin
- AR Ness
- AR Rechner
- AR Rumbold
- AS Baldwin Jr
- AS Binbrek
- AS Kaprelyants
- AS Wierzbicki
- AT McKie
- AV Lebedev
- AV Perkins
- AV Rao
- AW Maresso
- AY Andreyev
- AY Sun
- B Chakravarti
- B Chance
- B Cronin
- B de Valk
- B De Vries
- B Desoize
- B Drayer
- B Faller
- B Goodell
- B Halliwell
- B Halliwell
- B Halliwell
- B Halliwell
- B Halliwell
- B Halliwell
- B Halliwell
- B Halliwell
- B Huppertz
- B Jayawardhana
- B Kwak
- B Lachili
- B Lipinski
- B Mackenzie
- B Marshall
- B Mignotte
- B Oldenburg
- B Poeggeler
- B Pradines
- B Pradines
- B Regland
- B Russell
- B Schiessl
- B Shipley
- B Skibska
- B Sturm
- B Thorand
- B Wang
- B Wolff
- B Wolozin
- B Wolozin
- B Xu
- B Zhang
- B Zhou
- BA Maddux
- BA Molitoris
- BB Aggarwal
- BB Aggarwal
- BB Aggarwal
- BB Aggarwal
- BB Sizoo
- BB Song
- BB Song
- BC Daniels
- BC Jones
- BD LaMarca
- BH Havsteen
- BI Giasson
- BI Hoffman
- BJ Marshall
- BK Kennedy
- BK Rinehart
- BK Wagner
- BL Halvorsen
- BL Zhao
- BM Babior
- BN Ames
- BP Leung
- BP Oberg
- BP Yu
- BR Kwak
- BR Otto
- BS Chen
- BS van Asbeck
- BT Mossman
- BV Naidu
- BY Tung
- BØ Palsson
- C Arnaud
- C Beaumont
- C Behl
- C Biondi
- C Bolin
- C Bozzini
- C Breymann
- C Brooksbank
- C Bubici
- C Bubici
- C Burdon
- C Camaschella
- C Camaschella
- C Caris
- C Cavdar
- C Chen
- C Delaby
- C Demougeot
- C Finch
- C Fleury
- C García-Ruiz
- C Gasche
- C Gasche
- C Gerhäuser
- C Goble
- C Henry
- C Herce-Pagliai
- C Herder
- C Hershko
- C Hershko
- C Hershko
- C Hershko
- C Jacob
- C Kenyon
- C Knox
- C Kretz-Remy
- C Kunsch
- C Köhle
- C Leadbeater
- C Li
- C Lu
- C Manach
- C Manach
- C Manach
- C Mancuso
- C Moon
- C Moon
- C Mouralian
- C Muscoli
- C Peyssonnaux
- C Peyssonnaux
- C Peyssonnaux
- C Pigeon
- C Popa
- C Quintana
- C Ramassamy
- C Ramassamy
- C Ratledge
- C Rigamonti
- C Ritter
- C Ritter
- C Ritter
- C Savino
- C Savoia
- C Savoia
- C Schmeer
- C Shirky
- C Singh
- C Smith
- C Thrasivoulou
- C Trenkwalder
- C Troeger
- C Urbich
- C Vermylen
- C Vélez-Pardo
- C Vélez-Pardo
- C Wandersman
- C Xu
- CA Combs
- CA Dorrepaal
- CA Genco
- CA Hubel
- CA Hubel
- CA Hubel
- CA Hubel
- CA Lynch
- CA Papaharalambus
- CA Rice-Evans
- CA Rice-Evans
- CA Rice-Evans
- CA Rottkamp
- CC Chen
- CC Chiueh
- CC Hsieh
- CC Neto
- CC Neto
- CC Neto
- CC Winterbourn
- CD Davis
- CD Vulpe
- CE Beyer
- CE Finch
- CE Wrede
- CESDI
- CF Bolton
- CF Taylor
- CG Fraga
- CG Moles
- CG Pham
- CG Walker
- CH Wang
- CI Cook
- CJ Binder
- CJ Boos
- CJ Burrows
- CJ Chen
- CJ Hukshorn
- CJ Kaupke
- CJ Maynard
- CJ Needham
- CJ Parsa
- CJ Vaughan
- CJA Doelman
- CK Lee
- CK Roberts
- CK Roberts
- CK Sen
- CL Dent
- CM Anderson
- CM Craven
- CN Hales
- CN Lumeng
- CN Roy
- CP Doherty
- CP Martin
- CR Allerson
- CR Sunstein
- CS Shin
- CS Stevenson
- CS Yang
- CT Keith
- CT Murphy
- CT Noguchi
- CV Jongeneel
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- CW Pugh
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- CW Redman
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- CW Trenam
- CW Trenam
- CW Yang
- CWM Adams
- CY Wang
- CY Wu
- D Agnello
- D Barisani
- D Ben Shachar
- D Berg
- D Berg
- D Blum
- D Closa
- D De Roure
- D DeFaria Yeh
- D Fliser
- D Furlani
- D Galaris
- D Galter
- D Guagnozzi
- D HaMai
- D Hamerman
- D Harman
- D Howe
- D Hristovski
- D Hull
- D Hull
- D Imbert
- D Johnson
- D Kaur
- D Kaur
- D Lapenna
- D Law
- D Meyer
- D Mozaffarian
- D Noble
- D Noble
- D Ponraj
- D Prá
- D Rowley
- D Salvemini
- D Tapscott
- D Thorne
- D Trinder
- D Walz
- D Weininger
- D Yoon
- D Zozulinska
- DA Butterfield
- DA Butterfield
- DA Drechsel
- DA Fell
- DA Fell
- DA Rand
- DA Shoskes
- DA Weinstein
- DB Kell
- DB Kell
- DB Kell
- DB Kell
- DB Kell
- DB Kell
- DB Kell
- DB Kell
- DB Kell
- DB Kell
- DB Kell
- DB Kell
- DB Kell
- DB Kell
- DB Lovejoy
- DB Lovejoy
- DC Lau
- DC Souza-Costa
- DC Whitcomb
- DD Harrison-Findik
- DD Harrison-Findik
- DE Featherstone
- DE Ferrara
- DE Kelley
- DE Nelson
- DF Benyo
- DF Benyo
- DG Hackam
- DG Meyers
- DH Anderson
- DH Goetz
- DH Lee
- DH Lee
- DH Lee
- DH Lee
- DH Lee
- DH Walter
- DJ Fleming
- DJ Freeman
- DJ Grainger
- DJ Rader
- DJC Mackay
- DM Bailey
- DM Bailey
- DM Frazer
- DM Frazer
- DM Miller
- DM Niedowicz
- DM Paternoster
- DM Wojchowski
- DM Wrighting
- DN Granger
- DN Leung
- DN Seril
- DN Syed
- Douglas B Kell
- DP Bentley
- DR Bentley
- DR Flower
- DR Janero
- DR Petersen
- DR Richardson
- DR Richardson
- DR Richardson
- DR Richardson
- DR Richardson
- DR Richardson
- DR Rosen
- DR Swanson
- DR Swanson
- DR Zerbino
- DS Cassarino
- DS Grimes
- DS Kalinowski
- DS Kalinowski
- DS Kalinowski
- DS Kalinowski
- DS Warner
- DS Warner
- DS Wilson
- DT Dexter
- DW Kamp
- DW Kamp
- DW Killilea
- DW Lee
- DW Lee
- DW McCarey
- DW Reid
- DW Reif
- DW Swinkels
- DW Swinkels
- DX Bu
- E Aigner
- E Ates
- E Becker
- E Berenshtein
- E Berenshtein
- E Beutler
- E Bonilla
- E Bonilla
- E Butelli
- E Cadenas
- E Calabrese
- E Casanueva
- E Chwelatiuk
- E Corradini
- E Crimi
- E Crimi
- E Devrim
- E DiFederico
- E Donato
- E Floor
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- Publication venue
- Publication date
- 09/08/2008
- Field of study
The production of peroxide and superoxide is an inevitable consequence of
aerobic metabolism, and while these particular "reactive oxygen species" (ROSs)
can exhibit a number of biological effects, they are not of themselves
excessively reactive and thus they are not especially damaging at physiological
concentrations. However, their reactions with poorly liganded iron species can
lead to the catalytic production of the very reactive and dangerous hydroxyl
radical, which is exceptionally damaging, and a major cause of chronic
inflammation. We review the considerable and wide-ranging evidence for the
involvement of this combination of (su)peroxide and poorly liganded iron in a
large number of physiological and indeed pathological processes and
inflammatory disorders, especially those involving the progressive degradation
of cellular and organismal performance. These diseases share a great many
similarities and thus might be considered to have a common cause (i.e.
iron-catalysed free radical and especially hydroxyl radical generation). The
studies reviewed include those focused on a series of cardiovascular, metabolic
and neurological diseases, where iron can be found at the sites of plaques and
lesions, as well as studies showing the significance of iron to aging and
longevity. The effective chelation of iron by natural or synthetic ligands is
thus of major physiological (and potentially therapeutic) importance. As
systems properties, we need to recognise that physiological observables have
multiple molecular causes, and studying them in isolation leads to inconsistent
patterns of apparent causality when it is the simultaneous combination of
multiple factors that is responsible. This explains, for instance, the
decidedly mixed effects of antioxidants that have been observed, etc...Comment: 159 pages, including 9 Figs and 2184 reference
A922 Sequential measurement of 1 hour creatinine clearance (1-CRCL) in critically ill patients at risk of acute kidney injury (AKI)
- Author
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- De Freitas FF
- De Gasperi A
- de Hoyos EA
- De la Calle-Pedrosa N
- de la Fuente MV
- De La Fuente-Martos C
- De La Fuente-Martos C
- De La Rica AS
- De la Torre MA
- De Maglie M
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- de Molina FJ
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- de Oca Sandoval MA
- De Pascale G
- De Rosa S
- De Sanctis F
- De Silva AP
- De Sousa I
- de Vera AP
- de Wilde W
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- Deblier I
- DeBrunnar R
- Del Arco A
- Del Moral OL
- Del Olmo R
- Del Rosario CG
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- Descotte E
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- Di Gravio V
- Di Gregorio A
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- Dimopoulou IK
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- Elbers PW
- Elgendy M
- Eliet J
- Emmanuel J
- Emmerich M
- Encina B
- Endacott R
- Endacott R
- Engelberts D
- ENVIN-HELICS Study Group
- Erb J
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- Escórcio S
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- Estagnasie P
- Esteban A
- Estella A
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- Fave G
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- Fernandez R
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- Fernández L
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- Ferraz AB
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- Ferri F
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- Fiks T
- Fiks T
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- Filho CA
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- FINNRESUSCI Study Group
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- Fleischmann E
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- Frithiof R
- Fritz C
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- Frontera PR
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- Gadgil S
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- García MF
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- García-Olivares P
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- Genc D
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- Geri G
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- GETGAG/SEMICYUC
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- Gonçalves B
- Goodwin S
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- Gordon M
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- Gouveia J
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- Hernández-Tejedor A
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- Huang WC
- Huang WC
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- Hung WT
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- Idei M
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- Ignacio ML
- Iida A
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- Ilyina V
- Imanaka H
- Inaloo S
- Ince C
- Iotti GA
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- IPREA Study Group
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- Itenov TS
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- Jang BH
- Janotka M
- Janotka M
- Janotka M
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- Jansen N
- Japan Septic Disseminated Intravascular Coagulation (JSEPTIC DIC) study group
- Jardim JJ
- Jardim M
- Jareño A
- Javadpour S
- Jayasinghe S
- Jean-Baptiste S
- Jean-Baptiste S
- Jensen AE
- Jensen JU
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- Jeong IY
- Jeong WY
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- Jiao LR
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- Jiménez GJ
- Jo YH
- Joachim J
- Jochmans S
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- Jonas M
- Jonas M
- Jones C
- Joshi R
- Joshi V
- Jovaisa T
- JSEPTIC (Japanese Society of Education for Physicians and Trainees in Intensive Care) Clinical Trial Group
- Juan WC
- Juanas CA
- Judickas S
- Juez A
- Juliarena A
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- Jun IG
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- Junior JM
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- Kaminsky GE
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- Kang Y
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- Katabami K
- Katabami K
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- Kim HJ
- Kim JM
- Kim JM
- Kim JW
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- Ko SB
- Kobayashi A
- Koco E
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- Kodate A
- Kodate A
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- Kolnikova I
- Komuro T
- Kondili E
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- Kouatchet A
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- Krishna B
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- Kruger A
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- Ku NS
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- Kuebler WM
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- Kulkarni AP
- Kumari BK
- Kumbamu A
- Kunze-Szikszay N
- Kurmukov IA
- Kurth T
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- Kwon HM
- Kwon WY
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- Labra C
- Lacerda P
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- Lafaurie M
- Lafuente E
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- Lagos R
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- Lai CH
- Lake K
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- Lapteva K
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- Latini R
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- Latini R
- Latorre J
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- Lavrentieva A
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- Lheureux O
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- Lichtenstein D
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- Lin KC
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- Lin WC
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- Lischinsky A
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- Lobo-Civico A
- Loizou C
- Lombardo MD
- Londoño JG
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- Lopez-Gude MJ
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- Loudet CI
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- MacKay A
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- Mackey G
- MacPhee I
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- Madueño VP
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- Maekawa K
- Maekawa K
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- Maghsoudi B
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- Magnoni S
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- Maistry N
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- Mariani M
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- Marin-Mateos H
- Marine-Vidal J
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- Marmanidou K
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- Martín-Loeches I
- Martín-Loeches I
- Martínez F
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- Martínez M
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- Martínez NA
- Martínez-Carmona JF
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- Mejías CR
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- Mendes A
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- Menendez R
- Mengelle C
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- Mercat A
- Mercat A
- Mergulhão PJ
- Merino-Vega D
- Messenger D
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- Midwinter MJ
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- Miguelena PR
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- Mora-Ordóñez JM
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- Morimoto T
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- Morán I
- Motos A
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- Mukherjee DN
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- Okayama Research Investigation Organizing Network (ORION)investigators
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- Olavarria E
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- Palencia E
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- St George’s University of London
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- Student Research Committee - Shiraz University of Medical Sciences
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- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2016
- Field of study
Meeting abstrac
AusTraits, a curated plant trait database for the Australian flora
- Author
- Adams MA
- Ahrens CW
- Alfonzetti M
- Allen S
- Andrew SC
- Angevin T
- Apgaua DMG
- Arndt S
- Atkin OK
- Atkinson J
- Auld T
- Baker A
- Baxter C
- Bean A
- Blackman CJ
- Bloomfeld K
- Bowman DMJS
- Bragg J
- Brodribb TJ
- Buckton G
- Burrows G
- Caldwell E
- Camac J
- Carpenter R
- Catford J
- Cawthray GR
- Cernusak LA
- Chandler G
- Chapman AR
- Cheal D
- Cheesman AW
- Chen S-C
- Choat B
- Clinton B
- Clode PL
- Coleman H
- Cornwell WK
- Cosgrove M
- Crisp M
- Cross E
- Crous KY
- Cunningham S
- Curran T
- Curtis E
- Daws MI
- de Tombeur F
- DeGabriel JL
- Denton MD
- Dong N
- Du P
- Duan H
- Duncan DH
- Duncan RP
- Duretto M
- Dwyer JM
- Edwards C
- Esperon-Rodriguez M
- Evans JR
- Everingham SE
- Falster D
- Farrell C
- Firn J
- Fonseca CR
- French BJ
- Frood D
- Fuchs A
- Funk JL
- Gallagher R
- Geange SR
- Ghannoum O
- Gleason SM
- Gosper CR
- Gray E
- Groom PK
- Grootemaat S
- Gross C
- Guerin G
- Guja L
- Hahs AK
- Harrison MT
- Hayes PE
- Henery M
- Hochuli D
- Howell J
- Huang G
- Hughes L
- Huisman J
- Ilic J
- Indiarto D
- Jagdish A
- Jin D
- Jordan G
- Jurado E
- Kanowski J
- Kar F
- Kasel S
- Kellermann J
- Kenny B
- Kohout M
- Kooyman RM
- Kotowska MM
- Lai HR
- Laliberte E
- Lambers H
- Lamont BB
- Lanfear R
- Laughlin DC
- Laugier-kitchener B-A
- Laurance S
- Lawson J
- Lehmann CER
- Leigh A
- Leishman MR
- Lenz T
- Lepschi B
- Lewis JD
- Lim F
- Liu U
- Lopez-Martinez A
- Lord J
- Lusk CH
- Macinnis-Ng C
- Magallon S
- Manea A
- Mayfeld M
- McCarthy JK
- McPherson H
- Meers T
- Metcalfe DJ
- Milberg P
- Mokany K
- Moles AT
- Monro A
- Moore BD
- Moore N
- Morgan JW
- Morris W
- Muir A
- Munroe S
- Nicholson A
- Nicolle D
- Nicotra AB
- Niinemets U
- North T
- O'Reilly-Nugent A
- O'Sullivan OS
- Oberle B
- Onoda Y
- Ooi MKJ
- Osborne CP
- Paczkowska G
- Pekin B
- Pereira CG
- Pickering C
- Pickup M
- Pollock LJ
- Poot P
- Powell JR
- Power S
- Prentice IC
- Prior L
- Prober SM
- Read J
- Reynolds V
- Richards AE
- Richardson B
- Roderick ML
- Rosell JA
- Rossetto M
- Rye B
- Rymer PD
- Sams M
- Sanson G
- Sauquet H
- Schmidt S
- Schoenenberger J
- Schulze E-D
- Sendall K
- Sinclair S
- Smith B
- Smith R
- Soper F
- Sparrow B
- Standish RJ
- Staples TL
- Stephens R
- Szota C
- Taseski G
- Tasker E
- Thomas F
- Tissue DT
- Tjoelker MG
- Tng DYP
- Tomlinson K
- Turner NC
- van der Merwe M
- van Langevelde F
- Veneklaas EJ
- Venn S
- Vesk P
- Vlasveld C
- von Balthazar M
- Vorontsova MS
- Warren CA
- Warwick N
- Weerasinghe LK
- Wells J
- Wenk EH
- Westoby M
- White M
- Williams NSG
- Wills J
- Wilson PG
- Wright IJ
- Yates C
- Zanne AE
- Zemunik G
- Zieminska K
- Publication venue
- Springer Nature
- Publication date
- 01/01/2021
- Field of study
We introduce the AusTraits database - a compilation of values of plant traits for taxa in the Australian flora (hereafter AusTraits). AusTraits synthesises data on 448 traits across 28,640 taxa from field campaigns, published literature, taxonomic monographs, and individual taxon descriptions. Traits vary in scope from physiological measures of performance (e.g. photosynthetic gas exchange, water-use efficiency) to morphological attributes (e.g. leaf area, seed mass, plant height) which link to aspects of ecological variation. AusTraits contains curated and harmonised individual- and species-level measurements coupled to, where available, contextual information on site properties and experimental conditions. This article provides information on version 3.0.2 of AusTraits which contains data for 997,808 trait-by-taxon combinations. We envision AusTraits as an ongoing collaborative initiative for easily archiving and sharing trait data, which also provides a template for other national or regional initiatives globally to fill persistent gaps in trait knowledge
"Lucy, Take the Noodle Box!": Domestic Object Manipulation Using Movement Primitives and Whole Body Motion
- Author
- Publication venue
- Publication date
- 01/12/2019
- Field of study
For robots acting - and failing - in everyday environments, a predictable behaviour representation is important so that it can be utilised for failure analysis, recovery, and subsequent improvement. Learning from demonstration combined with dynamic motion primitives is one commonly used technique for creating models that are easy to analyse and interpret; however, mobile manipulators complicate such models since they need the ability to synchronise arm and base motions for performing purposeful tasks. In this paper, we analyse dynamic motion primitives in the context of a mobile manipulator - a Toyota Human Support Robot (HSR)- and introduce a small extension of dynamic motion primitives that makes it possible to perform whole body motion with a mobile manipulator. We then present an extensive set of experiments in which our robot was grasping various everyday objects in a domestic environment, where a sequence of object detection, pose estimation, and manipulation was required for successfully completing the task. Our experiments demonstrate the feasibility of the proposed whole body motion framework for everyday object manipulation, but also illustrate the necessity for highly adaptive manipulation strategies that make better use of a robot's perceptual capabilities
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