1,554 research outputs found
Aerodynamic spike nozzle Patent
Constructing fluid spike nozzle to eliminate heat transfer and high temperature problems inherent in physical spike
Early Contrast Enhancement: a novel Magnetic Resonance Imaging biomarker of pleural malignancy
Introduction:
Pleural Malignancy (PM) is often occult on subjective radiological assessment. We sought to define a novel, semi-objective Magnetic Resonance Imaging (MRI) biomarker of PM, targeted to increased tumour microvessel density (MVD) and applicable to minimal pleural thickening.
Materials and methods:
60 consecutive patients with suspected PM underwent contrast-enhanced 3-T MRI then pleural biopsy. In 58/60, parietal pleura signal intensity (SI) was measured in multiple regions of interest (ROI) at multiple time-points, generating ROI SI/time curves and Mean SI gradient (MSIG: SI increment/time). The diagnostic performance of Early Contrast Enhancement (ECE; which was defined as a SI peak in at least one ROI at or before 4.5 min) was compared with subjective MRI and Computed Tomography (CT) morphology results. MSIG was correlated against tumour MVD (based on Factor VIII immunostain) in 31 patients with Mesothelioma.
Results:
71% (41/58) patients had PM. Pleural thickening was <10 mm in 49/58 (84%). ECE sensitivity was 83% (95% CI 61–94%), specificity 83% (95% CI 68–91%), positive predictive value 68% (95% CI 47–84%), negative predictive value 92% (78–97%). ECE performance was similar or superior to subjective CT and MRI. MSIG correlated with MVD (r = 0.4258, p = .02).
Discussion:
ECE is a semi-objective, perfusion-based biomarker of PM, measurable in minimal pleural thickening. Further studies are warranted
Two-body correlations in N-body boson systems
We formulate a method to study two-body correlations in a system of N
identical bosons interacting via central two-body potentials. We use the
adiabatic hyperspherical approach and assume a Faddeev-like decomposition of
the wave function. For a fixed hyperradius we derive variationally an optimal
integro-differential equation for hyperangular eigenvalue and wave function.
This equation reduces substantially by assuming the interaction range much
smaller than the size of the N-body system. At most one-dimensional integrals
then remain. We view a Bose-Einstein condensate pictorially as a structure in
the landscape of the potential given as a function of the one-dimensional
hyperradial coordinate. The quantum states of the condensate can be located in
one of the two potential minima. We derive and discuss properties of the
solutions and illustrate with numerical results. The correlations lower the
interaction energy substantially. The new multi-body Efimov states are
solutions independent of details of the two-body potential. We compare with
mean-field results and available experimental data.Comment: 19 pages (RevTeX4), 13 figures (latex). Journal-link:
http://pra.aps.org
Cold Bose gases with large scattering lengths
We calculate the energy and condensate fraction for a dense system of bosons
interacting through an attractive short range interaction with positive s-wave
scattering length . At high densities, , the energy per particle,
chemical potential, and square of the sound speed are independent of the
scattering length and proportional to , as in Fermi systems.Comment: 4 pages, 3 figure
Bayesian Inference in Processing Experimental Data: Principles and Basic Applications
This report introduces general ideas and some basic methods of the Bayesian
probability theory applied to physics measurements. Our aim is to make the
reader familiar, through examples rather than rigorous formalism, with concepts
such as: model comparison (including the automatic Ockham's Razor filter
provided by the Bayesian approach); parametric inference; quantification of the
uncertainty about the value of physical quantities, also taking into account
systematic effects; role of marginalization; posterior characterization;
predictive distributions; hierarchical modelling and hyperparameters; Gaussian
approximation of the posterior and recovery of conventional methods, especially
maximum likelihood and chi-square fits under well defined conditions; conjugate
priors, transformation invariance and maximum entropy motivated priors; Monte
Carlo estimates of expectation, including a short introduction to Markov Chain
Monte Carlo methods.Comment: 40 pages, 2 figures, invited paper for Reports on Progress in Physic
AUDIT STATE DEPENDENT TAXPAYER COMPLIANCE: THEORY AND EVIDENCE FROM COLOMBIA
We develop and analyze a dynamic model of individual taxpayer compliance choice that predicts “audit state dependent taxpayer compliance”, by distinguishing between naïve and myopic behavior versus sophisticated and forward-looking behavior. We then test experimentally the audit state dependent model by reporting the results from the first tax compliance experiment run in Colombia. Consistent with previous studies as well as theoretical predictions, we find that subjects’ compliance rates increase in the audit probability and in the fine rate. We also find more novel results, both theoretically and empirically: fine rates should be increased after an audit to discourage otherwise-increased underreporting, and “nudging” myopic individuals toward reporting a constant rather than a fluctuating proportion of income would benefit both the taxpayer and the tax authority
Comparing nuclear power trajectories in Germany and the UK: from ‘regimes' to ‘democracies’ in sociotechnical transitions and Discontinuities
This paper focuses on arguably the single most striking contrast in contemporary major energy politics in Europe (and even the developed world as a whole): the starkly differing civil nuclear policies of Germany and the UK. Germany is seeking entirely to phase out nuclear power by 2022. Yet the UK advocates a ‘nuclear renaissance’, promoting the most ambitious new nuclear construction programme in Western Europe.Here,this paper poses a simple yet quite fundamental question: what are the particular divergent conditions most strongly implicated in the contrasting developments in these two countries. With nuclear playing such an iconic role in historical discussions over technological continuity and transformation, answering this may assist in wider understandings of sociotechnical incumbency and discontinuity in the burgeoning field of‘sustainability transitions’. To this end, an ‘abductive’ approach is taken: deploying nine potentially relevant criteria for understanding the different directions pursued in Germany and the UK. Together constituted by 30 parameters spanning literatures related to socio-technical regimes in general as well as nuclear technology in particular, the criteria are divided into those that are ‘internal’ and ‘external’ to the ‘focal regime configuration’ of nuclear power and associated ‘challenger technologies’ like renewables.
It is ‘internal’ criteria that are emphasised in conventional sociotechnical regime theory, with ‘external’ criteria relatively less well explored. Asking under each criterion whether attempted discontinuation of nuclear power would be more likely in Germany or the UK, a clear picture emerges. ‘Internal’ criteria suggest attempted nuclear discontinuation should be more likely in the UK than in Germany– the reverse of what is occurring.
‘External’ criteria are more aligned with observed dynamics –especially those relating to military nuclear commitments and broader ‘qualities of democracy’. Despite many differences of framing concerning exactly what constitutes ‘democracy’, a rich political science literature on this point is unanimous in characterising Germany more positively than the UK. Although based only on a single case,a potentially important question is nonetheless raised as to whether sociotechnical regime theory might usefully give greater attention to the general importance of various aspects of democracy in constituting conditions for significant technological discontinuities and transformations. If so, the policy implications are significant. A number of important areas are identified for future research, including the roles of diverse understandings and specific aspects of democracy and the particular relevance of military nuclear commitments– whose under-discussion in civil nuclear policy literatures raises its own questions of democratic accountability
Crossovers in Unitary Fermi Systems
Universality and crossover is described for attractive and repulsive
interactions where, respectively, the BCS-BEC crossover takes place and a
ferromagnetic phase transition is claimed. Crossovers are also described for
optical lattices and multicomponent systems. The crossovers, universal
parameters and phase transitions are described within the Leggett and NSR
models and calculated in detail within the Jastrow-Slater approximation. The
physics of ultracold Fermi atoms is applied to neutron, nuclear and quark
matter, nuclei and electrons in solids whenever possible. Specifically, the
differences between optical lattices and cuprates is discussed w.r.t.
antiferromagnetic, d-wave superfluid phases and phase separation.Comment: 50 pages, 15 figures. Contribution to Lecture Notes in Physics
"BCS-BEC crossover and the Unitary Fermi Gas" edited by W. Zwerge
- …