Investigation of the long-term sustainability of changes in appetite after weight loss

Background/Objective Diet-induced weight loss (WL) leads to a compensatory increase in appetite and changes in the plasma concentration of appetite-regulating hormones are likely to play a role. Whether these changes are transient or sustained remains unclear. This study aimed to assess if changes in subjective and objective appetite markers observed with WL are sustained after 1 year (1Y).Subjects/Methods In total 100 (45 males) individuals with obesity (BMI: 37 +/- 4 kg/m(2), age: 43 +/- 10 years) underwent 8 weeks (wks) of a very-low energy diet (VLED), followed by 4 wks refeeding, and a 1Y maintenance program. Fasting/postprandial subjective ratings of hunger, fullness, desire to eat, and prospective food consumption (PFC) were assessed, and plasma concentration of active ghrelin (AG), total peptide YY (PYY), active glucagon-like peptide 1, cholecystokinin (CCK), and insulin measured, at baseline, week 13 (Wk13) and 1Y.Results At Wk13, 16% WL (-18 +/- 1 kg, P < 0.001) was associated with a significant increase in fasting and postprandial hunger ratings (P < 0.01 and P < 0.05, respectively), and postprandial fullness (P < 0.01) combined with a reduction in PFC (P < 0.001). These were accompanied by a significant rise in basal and postprandial AG concentrations (P < 0.001, for both), a reduction in postprandial CCK (P < 0.01) and in basal and postprandial insulin (P < 0.001). At 1Y follow-up, with sustained WL (15%; -16 +/- 1 kg, P < 0.001), fasting hunger and postprandial fullness ratings remained increased (P < 0.05 for both), and postprandial PFC reduced (P < 0.001). Basal and postprandial AG remained elevated and insulin reduced (P < 0.001, for all), while postprandial CCK was increased (P < 0.01) and PYY decreased (P < 0.001).Conclusion With a 15% sustained WL at 1Y, the drive to eat in the fasting state is increased, but this may be balanced out by raised postprandial feelings of fullness. To assist with WL maintenance, new strategies are required to manage increased hunger and drive to eat

Zoneamento agroclimático para oliveira no estado do Rio Grande do Sul.

bitstream/CPACT-2010/12255/1/documento-259.pd

The Exact Ground State of the Frenkel-Kontorova Model with Repeated Parabolic Potential: I. Basic Results

The problem of finding the exact energies and configurations for the Frenkel-Kontorova model consisting of particles in one dimension connected to their nearest-neighbors by springs and placed in a periodic potential consisting of segments from parabolas of identical (positive) curvature but arbitrary height and spacing, is reduced to that of minimizing a certain convex function defined on a finite simplex.Comment: 12 RevTeX pages, using AMS-Fonts (amssym.tex,amssym.def), 6 Postscript figures, accepted by Phys. Rev.

Mapping quantitative trait loci in Gallus gallus using principal components.

Projeto/Plano de Ação: 01.06.10.602-03

Efeito do Deltamethrin e Mancozeb sobre Anthistarcha binocularis (LEP., Gelechiidae), Selenothrips rubrocinctus (THYS., Thripidae) e Aphis gossypii (HOM., Aphididae) em cajueiro.

Foi estudado no municipio de Aracati, Ceara, Brasil, o efeito do Deltamethrin CE e SC (a 14,36 g e 14,39 g do i. a./ha, respectivamente e do fungicida mancozeb ( a 800 g do i. a./ha) nas populacoes da broca - das - pontas. (Anthistarcba binocularis), tripes (Selenotbrips rubrocinctus) e pulgao (Aphis gossypii), em cajueiro (Anacardium occidentale L.). O inseticida piretroide deltamethrin foi eficiente no controle da broca-das-pontas e do tripes, tendo, no entanto, induzido o aumento da populacao de pulgoesbitstream/CNPAT-2010/1892/1/Bp-006.pd

EXPERIMENTAL AND NUMERICAL EVALUATION OF AN IN-FLIGHT ANGLE OF ATTACK MEASUREMENT SYSTEM FOR HIGH POWER MODEL ROCKETS

The angle of attack (α) affects the drag, flight path, and flight stability during rocket ascent. This work proposes an in-flight α measurement system based on pressure measurements at the surface of the nosecone for low apogee rockets. An electronic micro differential pressure transducer was selected to measure the pressure difference between selected points in the rocket’s nosecone. Wind tunnel tests were performed to correlate the α with the sensor output at low Mach numbers (Ma ≃ 0.08). The experimental results were further used as a reference for the construction of CFD models of the external flow in the rocket’s nosecone with the aim of predicting the measurements in an extended Mach number range (up to Ma ≃ 0.7). The numerical results allowed for an extended model correlating α with the differential pressure transducer output (Ch). The estimate of model’s errors completes the analysis

Controlling a resonant transmission across the δ′\delta'-potential: the inverse problem

Recently, the non-zero transmission of a quantum particle through the one-dimensional singular potential given in the form of the derivative of Dirac's delta function, $\lambda \delta'(x)$, with $\lambda \in \R$, being a potential strength constant, has been discussed by several authors. The transmission occurs at certain discrete values of $\lambda$ forming a resonance set ${\lambda_n}_{n=1}^\infty$. For $\lambda \notin {\lambda_n}_{n=1}^\infty$ this potential has been shown to be a perfectly reflecting wall. However, this resonant transmission takes place only in the case when the regularization of the distribution $\delta'(x)$ is constructed in a specific way. Otherwise, the $\delta'$-potential is fully non-transparent. Moreover, when the transmission is non-zero, the structure of a resonant set depends on a regularizing sequence $\Delta'_\varepsilon(x)$ that tends to $\delta'(x)$ in the sense of distributions as $\varepsilon \to 0$. Therefore, from a practical point of view, it would be interesting to have an inverse solution, i.e. for a given $\bar{\lambda} \in \R$ to construct such a regularizing sequence $\Delta'_\varepsilon(x)$ that the $\delta'$-potential at this value is transparent. If such a procedure is possible, then this value $\bar{\lambda}$ has to belong to a corresponding resonance set. The present paper is devoted to solving this problem and, as a result, the family of regularizing sequences is constructed by tuning adjustable parameters in the equations that provide a resonance transmission across the $\delta'$-potential.Comment: 21 pages, 4 figures. Corrections to the published version added; http://iopscience.iop.org/1751-8121/44/37/37530

Doença de Behçet: a nossa realidade

Introdução: A doença de Behçet é uma vasculite inflamatória sistémica, de etiologia desconhecida, caraterizada por episódios de recidiva de úlceras orais e genitais, lesões oculares e cutâneas, podendo atingir virtualmente todos os sistemas. As manifestações oculares são comuns e com consequências visuais importantes. O objectivo deste trabalho foi analisar os parâmetros demográficos, manifestações clinicas, terapêutica e principais complicações em doentes com doença de Behçet ocular. Métodos: Estudo descritivo e retrospetivo, que incluiu 11 doentes com o diagnóstico de doença de Behçet, segundo os critérios do ISG, observados na consulta de Inflamação Ocular do Hospital Prof. Doutor Fernando da Fonseca nos últimos 3 anos. Resultados: Identificaram-se 11 doentes, 5 homens e 6 mulheres, todos caucasianos. A idade média ao diagnóstico foi de 33,45±6,49 anos. A manifestação ocular foi o primeiro sinal da doença em 2 doentes. Em 72,7% dos casos as manifestações oculares foram bilaterais. Identificaram-se 4 casos de panuveíte, 3 de uveíte posterior, 2 de uveíte anterior, 1 de queratite e 1 caso de episclerite. O glaucoma e a catarata foram a complicação ocular mais frequente. O tratamento sistémico incluiu a corticoterapia oral em associação com terapêutica adjuvante imunossupressora, sendo os mais utilizados a azatioprina e a ciclosporina. Em 3 doentes houve necessidade de terapêutica biológica com infliximab para controlo da doença. Conclusão: A manifestação ocular mais frequente foi a panuveite. Esta doença pode condicionar complicações oculares com diminuição irreversível da acuidade visual. A orientação destes doentes exige uma abordagem global e inter-disciplinar

Identificação molecular de Lasiodiplodia parva associado ao camucamuzeiro.

Resumos do Congresso Paulista de Fitopatologia, 40., 2017, Campinas