62 research outputs found
Salbutamol effects on systemic potassium dynamics during and following intense continuous and intermittent exercise
Therapeutic glucocorticoid administration alters the diurnal pattern of dehydroepiandrosterone.
International audience: Significant alteration in hypothalamic-pituitary-adrenal function has been demonstrated in patients after short-term glucocorticoid therapy, but its impact on the circadian rhythm of steroid hormones has never been investigated. This study examined the effects of short-term prednisone administration on the diurnal patterns of dehydroepiandrosterone (DHEA) and testosterone. Saliva samples were collected from 11 healthy, physically active, male volunteers for DHEA and testosterone analysis, as follows: every 4Â h from 0800 to 2000Â h on 2 control days without medication, and after 1Â week of oral therapeutic prednisone treatment (60Â mg daily) (days 0-3). Overall, a diurnal decline in the two steroid hormones was observed on the control days. After short-term glucocorticoid administration, DHEA concentrations were significantly decreased with a complete disappearance of the DHEA diurnal pattern, which lasted 2Â days post-treatment. No glucocorticoid effect was observed for testosterone. The results indicate that short-term prednisone treatment affects the circadian pattern of saliva DHEA but not testosterone in healthy active volunteers. Further studies are necessary to determine whether this alteration in DHEA circadian pattern has clinical consequences in patients with chronic glucocorticoid therapy
Projet MUSE : Élaboration d’une approche globale des populations vulnérables vis-à -vis de la qualité de l’air intégrant les nouvelles technologies
Caffeine and saliva steroids in young healthy recreationally trained women: impact of regular caffeine intake
International audienceno abstrac
L'Europa in esilio. La migrazione degli intellettuali verso le Americhe tra le due guerre
Il fascicolo esamina in chiave comparativa alcuni casi di migrazioni culturale nel periodo compreso tra le due guerr
De la dispensation au plan pharmaceutique personnalisé : vers un modèle intégratif de pharmacie clinique
International audienc
De la dispensation au plan pharmaceutique personnalisé : vers un modèle intégratif de pharmacie clinique
International audienc
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