36 research outputs found

    Análise dos padrões fundamentais de movimento em escolares de sete a nove anos de idade

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    During childhood, a motor development phase involving the acquisition of fundamental motor patterns is observed from approximately two to seven years old. The aim of this study was to investigate the fundamental motor patterns developmental stage (jumping, running, kicking, throwing and receiving) in the 3rd period of kindergarten and 1st and 2nd series junior high school students as well. The data were recorded and later analyzed in accordance to McClenaghan & Gallahue's (1985) protocol. The results showed that the 3rd period group presented the movement patterns components in the elementary stage and the 1st year group was in a transition process between the elementary and mature stages. Finally, the 2nd year group presented the pattern components in the mature stage. The results suggest that the mature stage was achieved only between eight and nine years old contradicting some descriptive models (Gallahue & Ozmun, 1998; Tani et al., 1988).Uma das fases de desenvolvimento motor na infância, no qual se adquire os padrões fundamentais de movimento, estende-se aproximadamente dos dois aos sete anos de idade. O objetivo do presente estudo foi investigar o estágio de tais padrões (saltar, correr, chutar, arremessar e receber) de alunos praticantes de educação física escolar, do 3o. período do ensino infantil, 1a. e 2a. séries do ensino fundamental. Os dados foram filmados e posteriormente analisados conforme protocolo proposto por McClenaghan e Gallahue (1985). Os resultados mostraram que o grupo do 3o. período apresentou os componentes dos padrões de movimento no estágio elementar e o grupo da 1a. série encontrou-se em um processo de transição entre o estágio elementar e maduro. Por fim, o grupo da 2a. série apresentou os componentes dos padrões no estágio maduro. Os resultados sugerem que o estágio maduro foi atingido apenas entre oito e nove anos de idade, o que contradiz alguns modelos descritivos (Gallahue & Ozmun, 1998; Tani et al., 1988)

    Colecistectomia videolaparoscópica e convencional: comparação entre as técnicas

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    A colecistectomia videolaparoscópica é um procedimento cirúrgico considerado padrão ouro para o tratamento das patologias benignas da vesícula biliar. Ela apresenta como benefícios a redução da morbimortalidade, um menor tempo de recuperação pós-operatório, além de apresentar resultado cicatricial mais estético. Sua indicação se dá em casos de colelitíase sintomática, de colecistite aguda, de pancreatite de origem biliar,  na coledocolitíase e na presença de massas/pólipos na vesícula biliar. Deve-se destacar que como todo procedimento laparoscópico, o risco de conversão para uma colecistectomia aberta existe, podendo ocorrer mediante dificuldade técnica do procedimento,  pela presença de obstáculos como múltiplas aderências intra-abdominais ou mesmo por sangramentos não passíveis de controle por meio laparoscópico. Mesmo apresentando benefícios em relação à colecistectomia aberta, o procedimento laparoscópico pode ser contraindicado mediante patologia cardio-pulmonar que gere intolerabilidade ao pneumoperitônio, em casos de coagulopatia incorrigível ou doença metastática. Por fim, destaca-se que complicações como sangramentos, abscessos, vazamento de bile ou lesões intestinais ou do trato biliar também se fazem presentes nesse procedimento

    Prevention of hypertension in patients with pre-hypertension: protocol for the PREVER-prevention trial

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    <p>Abstract</p> <p>Background</p> <p>Blood pressure (BP) within pre-hypertensive levels confers higher cardiovascular risk and is an intermediate stage for full hypertension, which develops in an annual rate of 7 out of 100 individuals with 40 to 50 years of age. Non-drug interventions to prevent hypertension have had low effectiveness. In individuals with previous cardiovascular disease or diabetes, the use of BP-lowering agents reduces the incidence of major cardiovascular events. In the absence of higher baseline risk, the use of BP agents reduces the incidence of hypertension. The PREVER-prevention trial aims to investigate the efficacy, safety and feasibility of a population-based intervention to prevent the incidence of hypertension and the development of target-organ damage.</p> <p>Methods</p> <p>This is a randomized, double-blind, placebo-controlled clinical trial, with participants aged 30 to 70 years, with pre-hypertension. The trial arms will be chlorthalidone 12.5 mg plus amiloride 2.5 mg or identical placebo. The primary outcomes will be the incidence of hypertension, adverse events and development or worsening of microalbuminuria and of left ventricular hypertrophy in the EKG. The secondary outcomes will be fatal or non-fatal cardiovascular events: myocardial infarction, stroke, heart failure, evidence of new sub-clinical atherosclerosis, and sudden death. The study will last 18 months. The sample size was calculated on the basis of an incidence of hypertension of 14% in the control group, a size effect of 40%, power of 85% and P alpha of 5%, resulting in 625 participants per group. The project was approved by the Ethics committee of each participating institution.</p> <p>Discussion</p> <p>The early use of blood pressure-lowering drugs, particularly diuretics, which act on the main mechanism of blood pressure rising with age, may prevent cardiovascular events and the incidence of hypertension in individuals with hypertension. If this intervention shows to be effective and safe in a population-based perspective, it could be the basis for an innovative public health program to prevent hypertension in Brazil.</p> <p>Trial Registration</p> <p>Clinical Trials <a href="http://www.clinicaltrials.gov/ct2/show/NCT00970931">NCT00970931</a>.</p

    'Formidável contágio': epidemias, trabalho e recrutamento na Amazônia colonial (1660-1750)

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    ATLANTIC EPIPHYTES: a data set of vascular and non-vascular epiphyte plants and lichens from the Atlantic Forest

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    Epiphytes are hyper-diverse and one of the frequently undervalued life forms in plant surveys and biodiversity inventories. Epiphytes of the Atlantic Forest, one of the most endangered ecosystems in the world, have high endemism and radiated recently in the Pliocene. We aimed to (1) compile an extensive Atlantic Forest data set on vascular, non-vascular plants (including hemiepiphytes), and lichen epiphyte species occurrence and abundance; (2) describe the epiphyte distribution in the Atlantic Forest, in order to indicate future sampling efforts. Our work presents the first epiphyte data set with information on abundance and occurrence of epiphyte phorophyte species. All data compiled here come from three main sources provided by the authors: published sources (comprising peer-reviewed articles, books, and theses), unpublished data, and herbarium data. We compiled a data set composed of 2,095 species, from 89,270 holo/hemiepiphyte records, in the Atlantic Forest of Brazil, Argentina, Paraguay, and Uruguay, recorded from 1824 to early 2018. Most of the records were from qualitative data (occurrence only, 88%), well distributed throughout the Atlantic Forest. For quantitative records, the most common sampling method was individual trees (71%), followed by plot sampling (19%), and transect sampling (10%). Angiosperms (81%) were the most frequently registered group, and Bromeliaceae and Orchidaceae were the families with the greatest number of records (27,272 and 21,945, respectively). Ferns and Lycophytes presented fewer records than Angiosperms, and Polypodiaceae were the most recorded family, and more concentrated in the Southern and Southeastern regions. Data on non-vascular plants and lichens were scarce, with a few disjunct records concentrated in the Northeastern region of the Atlantic Forest. For all non-vascular plant records, Lejeuneaceae, a family of liverworts, was the most recorded family. We hope that our effort to organize scattered epiphyte data help advance the knowledge of epiphyte ecology, as well as our understanding of macroecological and biogeographical patterns in the Atlantic Forest. No copyright restrictions are associated with the data set. Please cite this Ecology Data Paper if the data are used in publication and teaching events. © 2019 The Authors. Ecology © 2019 The Ecological Society of Americ

    Canine visceral leishmaniasis in the Krenak indigenous community, Resplendor, Minas Gerais State, Brazil, 2007.

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    The authors conducted a cross-sectional study of the local canine population in the Krenak indigenous community to detect parasites of the genus Leishmania and identify the circulating species and the proportion of asymptomatic dogs, while investigating associations between canine infection and the dogs' sex, age, and hair length. A seroepidemiological survey was performed, including 63 dogs. All the animals underwent clinical examination to verify the presence of characteristic signs, and serum samples were taken for serological tests (ELISA, IIF). Infected dogs culled by the health service were necropsied and the material was analyzed using molecular diagnostic techniques. The cross-sectional study detected a 46% prevalence rate, and the circulating species was Leishmania (L.) chagasi. The statistical analysis showed no association between infection and the independent variables. The study generated data on the epidemiological situation with canine infection in the area, which was previously unknown.Foi realizado um estudo seccional para detectar, na população canina, a presença de parasitos do gênero Leishmania e a espécie circulante, a proporção de cães assintomáticos, investigando concomitantemente a existência de associações entre a infecção canina e as variáveis: sexo, idade e tipo de pelo dos cães. Para o estudo seccional, foi realizado um inquérito censitário, que avaliou 63 cães. Todos passaram por uma avaliação clínica para verificar a presença de sintomas característicos da infecção; amostras de soro foram coletadas para os testes sorológicos (ELISA, RIFI). Os cães positivos retirados pelo serviço de saúde foram necropsiados, e o material, analisado pelas técnicas de diagnóstico molecular. O estudo seccional realizado detectou uma prevalência de 46%, sendo a espécie circulante a Leishmania (L.) chagasi. A análise estatística não detectou nenhuma associação entre infecção e as variáveis investigadas. Este estudo possibilitou a geração de dados sobre a situação epidemiológica da infecção canina na área, o que antes era desconhecido

    Field randomized trial to evaluate the efficacy of the Leish - Tec vaccine against canine visceral leishmaniasis in anendemic area of Brazil.

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    Background: A canine vaccine remains a promising approach for effective control of visceral leishmaniasis(VL), given its complex epidemiology in areas where zoonotic VL is prevalent. Leish-Tec®is a recombi-nant vaccine, based on the Leishmania A2 antigen, against canine VL (CVL). It is, since 2014, the singlecommercial vaccine licensed in Brazil. Here, Leish-Tec®efficacy was estimated through a randomizedfield trial (RFT), in a highly VL endemic area.Methods: The RFT was conducted from 2008 to 2010 in an endemic area of southeastern Brazil, presentinga CVL seroprevalence of 41.9%. Eight hundred forty-seven seronegative dogs were randomly selected toreceive Leish-Tec®(n = 429) or placebo (n = 418). Animals were followed up by clinical, serological, andparasitological exams for 18 months. The CVL incidence in both groups was compared through proportionanalysis.Results: A significant reduction in the number of cases of CVL was observed in the vaccine group, ascompared with the placebo group, whether efficacy was estimated according to parasitological results(71.4%; 95% CI: 34.9–87.3%; p = 0.001; risk ratio = 0.287), by adding results of xenodiagnosis and parasito-logical exams (58.1%; 95% CI: 26.0–76.3%; p = 0.002; risk ratio = 0.419). Among the animals that convertedto a positive anti-A2 serology, efficacy reached 80.8% (95% CI: 37.6–94.1%, p = 0.001; risk ratio = 0.192).Xenodiagnosis has detected a reduction of 46.6% (p = 0.05) in transmission to sand flies from vaccinatedanimals presenting anti-A2 positive serology.Conclusion: The Leish-Tec®vaccine proved significantly effective for prophylaxis of CVL, after naturalchallenge assured by transmission of Leishmania parasites, in a highly endemic area. Noteworthy, thisreport has unveiled the complexity of performing a RFT for anti-CVL vaccines in Brazil, which may behelpful for designing of future studies
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