1,568 research outputs found

    Hybrid and Orbitally Excited Mesons in Full QCD

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    We present results for the hybrid meson spectrum produced by gluonic excitations in full QCD using Wilson fermions. For the spin-exotic mesons with J^{PC}=1^{-+}, 0^{+-}, and 2^{+-} we find the lightest state to be 1^{-+} with a mass of 1.9(2) GeV. Results obtained for orbitally excited mesons are also presented.Comment: LATTICE98(spectrum),3 pages, LaTeX2e File, 4 PS Figure

    Synthesis, Conformation and Antiproliferative Activity of Isothiazoloisoxazole 1,1-dioxides

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    Sixteen new isothiazoloisoxazole 1,1-dioxides, one new isothiazolotriazole and one new isothiazolopyrazole have been synthesised by using 1,3-dipolar cycloadditions to isothiazole 1,1-dioxides. One sub-set of these isothiazoloisoxazoles showed low μM activity against a human breast carcinoma cell line, whilst a second sub-set plus the isothiazolotriazole demonstrated an interesting restricted rotation of sterically hindered bridgehead substituents. A thiazete 1,1-dioxide produced from one of the isothiazole 1,1-dioxides underwent conversion into an unknown 1,2,3-oxathiazolin-2-oxide upon treatment with Lewis acids, but was inert towards 1,3-dipoles and cyclopropenones. Six supporting crystal structures are included

    Explorar el uso de indicadores fenológicos basados ??en MODIS NDVI para clasificar las categorías generales de hábitats forestales

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    The cost effective monitoring of habitats and their biodiversity remains a challenge to date. Earth Observation (EO) has a key role to play in mapping habitat and biodiversity in general, providing tools for the systematic collection of environmental data. The recent GEO-BON European Biodiversity Observation Network project (EBONE) established a framework for an integrated biodiversity monitoring system. Underlying this framework is the idea of integrating in situ with EO and a habitat classification scheme based on General Habitat Categories (GHC), designed with an Earth Observation-perspective. Here we report on EBONE work that explored the use of NDVI-derived phenology metrics for the identification and mapping of Forest GHCs. Thirty-one phenology metrics were extracted from MODIS NDVI time series for Europe. Classifications to discriminate forest types were performed based on a Random Forestsâ„¢ classifier in selected regions. Results indicate that date phenology metrics are generally more significant for forest type discrimination. The achieved class accuracies are generally not satisfactory, except for coniferous forests in homogeneous stands (77-82%). The main causes of low classification accuracies were identified as (i) the spatial resolution of the imagery (250 m) which led to mixed phenology signals; (ii) the GHC scheme classification design, which allows for parcels of heterogeneous covers, and (iii) the low number of the training samples available from field surveys. A mapping strategy integrating EO-based phenology with vegetation height information is expected to be more effective than a purely phenology-based approach

    Exploring the use of MODIS NDVI-based phenology indicators for classifying forest general habitat categories. Remote Sens

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    Abstract: The cost effective monitoring of habitats and their biodiversity remains a challenge to date. Earth Observation (EO) has a key role to play in mapping habitat and biodiversity in general, providing tools for the systematic collection of environmental data. The recent GEO-BON European Biodiversity Observation Network project (EBONE) established a framework for an integrated biodiversity monitoring system. Underlying this framework is the idea of integrating in situ with EO and a habitat classification scheme based on General Habitat Categories (GHC), designed with an Earth Observation-perspective. Here we report on EBONE work that explored the use of NDVI-derived phenology metrics for the identification and mapping of Forest GHCs. Thirty-one phenology metrics were extracted from MODIS NDVI time series for Europe. Classifications to discriminate forest types were performed based on a Random Forests ™ classifier in selected regions. Results indicate that date phenology metrics are generally more significant for forest type discrimination. The achieved class accuracies are generally not satisfactory, except for coniferous forests in homogeneous stands (77–82%). The main causes of low classification accuracies were identified as (i) the spatial resolution of the imagery (250 m) which led t

    Does greening of neotropical cities considerably mitigate carbon dioxide emissions? The case of Medellin, Colombia

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    Cities throughout the world are advocating highly promoted tree plantings as a climate change mitigation measure. Assessing the carbon offsets associated with urban trees relative to other climate change policies is vital for sustainable development, planning, and solving environmental and socio-economic problems, but is difficult in developing countries. We estimated and assessed carbon dioxide (CO2) storage, sequestration, and emission offsets by public trees in the Medellin Metropolitan Area, Colombia, as a viable Nature-Based Solution for the Neotropics. While previous studies have discussed nature-based solutions and explored urban tree carbon dynamics in high income countries, few have been conducted in tropical cities in low-middle income countries, particularly within South America. We used a public tree inventory for the Metropolitan Area of the Aburrá Valley and an available urban forest functional model, i-Tree Streets, calibrated for Colombia's context. We found that CO2 offsets from public trees were not as effective as cable cars or landfills. However, if available planting spaces are considered, carbon offsets become more competitive with cable cars and other air quality and socio-economic co-benefits are also provided. The use of carbon estimation models and the development of relevant carbon accounting protocols in Neotropical cities are also discussed. Our nature-based solution approach can be used to better guide management of urban forests to mitigate climate change and carbon offset accounting in tropical cities lacking available information. © 2017 by the authors

    Spatiotemporal Amplitude and Phase Retrieval of Bessel-X pulses using a Hartmann-Shack Sensor

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    We propose a new experimental technique, which allows for a complete characterization of ultrashort optical pulses both in space and in time. Combining the well-known Frequency-Resolved-Optical-Gating technique for the retrieval of the temporal profile of the pulse with a measurement of the near-field made with an Hartmann-Shack sensor, we are able to retrieve the spatiotemporal amplitude and phase profile of a Bessel-X pulse. By following the pulse evolution along the propagation direction we highlight the superluminal propagation of the pulse peak

    A conserved two-step binding for the UAF1 regulator to the USP12 deubiquitinating enzyme

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    AbstractRegulation of deubiquitinating enzyme (DUB) activity is an essential step for proper function of cellular ubiquitin signals. UAF1 is a WD40 repeat protein, which binds and activates three important DUBs, USP1, USP12 and USP46. Here, we report the crystal structure of the USP12-Ub/UAF1 complex at a resolution of 2.8Ã… and of UAF1 at 2.3Ã…. In the complex we find two potential sites for UAF1 binding, analogous to what was seen in a USP46/UAF1 complex. In line with these observed dual binding states, we show here that USP12/UAF1 complex has 1:2 stoichiometry in solution, with a two-step binding at 4nM and 325nM respectively. Mutagenesis studies show that the fingers sub-domain of USP12 interacts with UAF1 to form the high affinity interface. Our activation studies confirm that the high affinity binding is important for activation while the second UAF1 binding does not affect activation. Nevertheless, we show that this two step binding is conserved in the well-studied USP12 paralog, USP1. Our results highlight the interfaces essential for regulation of USP12 activity and show a conserved second binding of UAF1 which could be important for regulatory functions independent of USP12 activity

    Wideband THz time domain spectroscopy based on optical rectification and electro-optic sampling

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    We present an analytical model describing the full electromagnetic propagation in a THz time-domain spectroscopy (THz-TDS) system, from the THz pulses via Optical Rectification to the detection via Electro Optic-Sampling. While several investigations deal singularly with the many elements that constitute a THz-TDS, in our work we pay particular attention to the modelling of the time-frequency behaviour of all the stages which compose the experimental set-up. Therefore, our model considers the following main aspects: (i) pump beam focusing into the generation crystal; (ii) phase-matching inside both the generation and detection crystals; (iii) chromatic dispersion and absorption inside the crystals; (iv) Fabry-Perot effect; (v) diffraction outside, i.e. along the propagation, (vi) focalization and overlapping between THz and probe beams, (vii) electro-optic sampling. In order to validate our model, we report on the comparison between the simulations and the experimental data obtained from the same set-up, showing their good agreement

    Estimating aboveground biomass and carbon stocks in periurban Andean secondary forests using very high resolution imagery

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    Periurban forests are key to offsetting anthropogenic carbon emissions, but they are under constant threat from urbanization. In particular, secondary Neotropical forest types in Andean periurban areas have a high potential to store carbon, but are currently poorly characterized. To address this lack of information, we developed a method to estimate periurban aboveground biomass (AGB)-a proxy for multiple ecosystem services-of secondary Andean forests near Bogotá, Colombia, based on very high resolution (VHR) GeoEye-1, Pleiades-1A imagery and field-measured plot data. Specifically, we tested a series of different pre-processing workflows to derive six vegetation indices that were regressed against in situ estimates of AGB. Overall, the coupling of linear models and the Ratio Vegetation Index produced the most satisfactory results. Atmospheric and topographic correction proved to be key in improving model fit, especially in high aerosol and rugged terrain such as the Andes. Methods and findings provide baseline AGB and carbon stock information for little studied periurban Andean secondary forests. The methodological approach can also be used for integrating limited forest monitoring plot AGB data with very high resolution imagery for cost-effective modelling of ecosystem service provision from forests, monitoring reforestation and forest cover change, and for carbon offset assessments

    Identification of a protein encoded in the EB-viral open reading frame BMRF2

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    Using monospecific rabbit sera against a peptide derived from a potential antigenic region of the Epstein-Barr viral amino acid sequence encoded in the open reading frame BMRF2 we could identify a protein-complex of 53/55 kDa in chemically induced B95-8, P3HR1 and Raji cell lines. This protein could be shown to be membrane-associated, as predicted by previous computer analysis of the secondary structure and hydrophilicity pattern, and may be a member of EBV-induced membrane proteins in lytically infected cells
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