9 research outputs found

    Evaluating Metaphor Reification in Tangible Interfaces

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    International audienceMetaphors are a powerful conceptual device to reason about human actions. As such, they have been heavily used in designing and describing human computer interaction. Since they can address scripted text, verbal expression, imaging, sound, and gestures, they can also be considered in the design and analysis of multimodal interfaces. In this paper we discuss the description and evaluation of the relations between metaphors and their implementation in human computer interaction with a focus on tangible user interfaces (TUIs), a form of multimodal interface. The objective of this paper is to define how metaphors appear in a tangible context in order to support their evaluation. Relying on matching entities and operations between the domain of interaction and the domain of the digital application, we propose a conceptual framework based on three components: a structured representation of the mappings holding between the metaphor source, the metaphor target, the interface and the digital system; a conceptual model for describing metaphorical TUIs; three relevant properties, coherence, coverage and compliance, which define at what extent the implementation of a metaphorical tangible interface matches the metaphor. The conceptual framework is then validated and applied on a tangible prototype in an educational application

    Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock, 2012

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    OBJECTIVE: To provide an update to the "Surviving Sepsis Campaign Guidelines for Management of Severe Sepsis and Septic Shock," last published in 2008. DESIGN: A consensus committee of 68 international experts representing 30 international organizations was convened. Nominal groups were assembled at key international meetings (for those committee members attending the conference). A formal conflict of interest policy was developed at the onset of the process and enforced throughout. The entire guidelines process was conducted independent of any industry funding. A stand-alone meeting was held for all subgroup heads, co- and vice-chairs, and selected individuals. Teleconferences and electronic-based discussion among subgroups and among the entire committee served as an integral part of the development. METHODS: The authors were advised to follow the principles of the Grading of Recommendations Assessment, Development and Evaluation (GRADE) system to guide assessment of quality of evidence from high (A) to very low (D) and to determine the strength of recommendations as strong (1) or weak (2). The potential drawbacks of making strong recommendations in the presence of low-quality evidence were emphasized. Recommendations were classified into three groups: (1) those directly targeting severe sepsis; (2) those targeting general care of the critically ill patient and considered high priority in severe sepsis; and (3) pediatric considerations. RESULTS: Key recommendations and suggestions, listed by category, include: early quantitative resuscitation of the septic patient during the first 6 h after recognition (1C); blood cultures before antibiotic therapy (1C); imaging studies performed promptly to confirm a potential source of infection (UG); administration of broad-spectrum antimicrobials therapy within 1 h of the recognition of septic shock (1B) and severe sepsis without septic shock (1C) as the goal of therapy; reassessment of antimicrobial therapy daily for de-escalation, when appropriate (1B); infection source control with attention to the balance of risks and benefits of the chosen method within 12 h of diagnosis (1C); initial fluid resuscitation with crystalloid (1B) and consideration of the addition of albumin in patients who continue to require substantial amounts of crystalloid to maintain adequate mean arterial pressure (2C) and the avoidance of hetastarch formulations (1B); initial fluid challenge in patients with sepsis-induced tissue hypoperfusion and suspicion of hypovolemia to achieve a minimum of 30 mL/kg of crystalloids (more rapid administration and greater amounts of fluid may be needed in some patients (1C); fluid challenge technique continued as long as hemodynamic improvement is based on either dynamic or static variables (UG); norepinephrine as the first-choice vasopressor to maintain mean arterial pressure ≥65 mmHg (1B); epinephrine when an additional agent is needed to maintain adequate blood pressure (2B); vasopressin (0.03 U/min) can be added to norepinephrine to either raise mean arterial pressure to target or to decrease norepinephrine dose but should not be used as the initial vasopressor (UG); dopamine is not recommended except in highly selected circumstances (2C); dobutamine infusion administered or added to vasopressor in the presence of (a) myocardial dysfunction as suggested by elevated cardiac filling pressures and low cardiac output, or (b) ongoing signs of hypoperfusion despite achieving adequate intravascular volume and adequate mean arterial pressure (1C); avoiding use of intravenous hydrocortisone in adult septic shock patients if adequate fluid resuscitation and vasopressor therapy are able to restore hemodynamic stability (2C); hemoglobin target of 7-9 g/dL in the absence of tissue hypoperfusion, ischemic coronary artery disease, or acute hemorrhage (1B); low tidal volume (1A) and limitation of inspiratory plateau pressure (1B) for acute respiratory distress syndrome (ARDS); application of at least a minimal amount of positive end-expiratory pressure (PEEP) in ARDS (1B); higher rather than lower level of PEEP for patients with sepsis-induced moderate or severe ARDS (2C); recruitment maneuvers in sepsis patients with severe refractory hypoxemia due to ARDS (2C); prone positioning in sepsis-induced ARDS patients with a PaO (2)/FiO (2) ratio of ≤100 mm Hg in facilities that have experience with such practices (2C); head-of-bed elevation in mechanically ventilated patients unless contraindicated (1B); a conservative fluid strategy for patients with established ARDS who do not have evidence of tissue hypoperfusion (1C); protocols for weaning and sedation (1A); minimizing use of either intermittent bolus sedation or continuous infusion sedation targeting specific titration endpoints (1B); avoidance of neuromuscular blockers if possible in the septic patient without ARDS (1C); a short course of neuromuscular blocker (no longer than 48 h) for patients with early ARDS and a PaO (2)/FI O (2) 180 mg/dL, targeting an upper blood glucose ≤180 mg/dL (1A); equivalency of continuous veno-venous hemofiltration or intermittent hemodialysis (2B); prophylaxis for deep vein thrombosis (1B); use of stress ulcer prophylaxis to prevent upper gastrointestinal bleeding in patients with bleeding risk factors (1B); oral or enteral (if necessary) feedings, as tolerated, rather than either complete fasting or provision of only intravenous glucose within the first 48 h after a diagnosis of severe sepsis/septic shock (2C); and addressing goals of care, including treatment plans and end-of-life planning (as appropriate) (1B), as early as feasible, but within 72 h of intensive care unit admission (2C). Recommendations specific to pediatric severe sepsis include: therapy with face mask oxygen, high flow nasal cannula oxygen, or nasopharyngeal continuous PEEP in the presence of respiratory distress and hypoxemia (2C), use of physical examination therapeutic endpoints such as capillary refill (2C); for septic shock associated with hypovolemia, the use of crystalloids or albumin to deliver a bolus of 20 mL/kg of crystalloids (or albumin equivalent) over 5-10 min (2C); more common use of inotropes and vasodilators for low cardiac output septic shock associated with elevated systemic vascular resistance (2C); and use of hydrocortisone only in children with suspected or proven "absolute"' adrenal insufficiency (2C). CONCLUSIONS: Strong agreement existed among a large cohort of international experts regarding many level 1 recommendations for the best care of patients with severe sepsis. Although a significant number of aspects of care have relatively weak support, evidence-based recommendations regarding the acute management of sepsis and septic shock are the foundation of improved outcomes for this important group of critically ill patients

    Utilizing heat regeneration within hydraulic pressure accumulator

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    Tekniikan kehittyessä toimilaitteiden ja järjestelmien suunnittelussa ja toteutuksessa laitteiden ja koneiden energia- ja kustannustehokkuus nousevat jatkuvasti tärkeämpään rooliin. Hydraulisilla toimilaitteilla saavutetaan korkea tehotiheys, mutta järjestelmien kokonaishyötysuhde on usein heikko. Hyötysuhdetta voidaan nostaa lisäämällä järjestelmiin energian talteenotto, jolloin työkierroista voidaan normaalisti hukkaan menevää energiaa varastoida ja käyttää uudelleen seuraavassa työkierrossa. Hydraulisissa energian talteenottojärjestelmissä energiaa varastoidaan tyypillisesti hydraulipaineakkuihin. Paineakuissa energia varastoituu puristamalla paineakun kaasutilavuudessa olevaa kaasua. Puristusvaiheen aikana kaasun lämpötila nousee ja lämpö alkaa virrata paineakusta ympäristöön. Tämä energian virtaaminen ympäristöön muodostaa merkittävimmän yksittäisen paineakun hyötysuhdetta laskevan tekijän. Tämän työn tavoitteena oli nostaa mäntäpaineakun hyötysuhdetta hyödyntämällä lämmön regenerointia. Lämmön regeneroinnilla pyritään varastoimaan kaasussa puristusvaiheessa syntyvä lämpöenergia lämpöregeneraattoriin ja luovuttamaan energia takaisin kaasuun paineakun purkusyklin aikana. Työssä suunniteltu lämpöregeneraattori perustui faasimuutosmateriaalien hyödyntämiseen energiavarastona. Faasimuutosmateriaalit soveltuvat erinomaisesti lämpövarastoiksi, sillä ne kykenevät sitomaan suuren määrän energiaa faasimuutoksen aikana, jolloin työssä suunniteltu lämpöregeneraattori saatiin mahdutettua mäntäpaineakun sisälle. Työssä saatujen mittaustuloksien perusteella pääteltiin, että lämpöregeneraattorin dynamiikan merkitys nousi merkittävämmäksi kuin lämpöregeneraattorin kyky varastoida lämpöenergiaa. Lämpöregeneraattorin hidas dynamiikka ei mahdollista tehokasta energian talteenottoa nopeista puristus- tai purkusykleistä, ja tämän takia lämpöregeneraattorista saatava hyöty jäi pieneksi. Työssä toteutetulla lämpöregeneraattorilla saavutettiin parhaimmillaan 3 prosenttiyksikön hyötysuhteen nousu verrattaessa samaan mäntäpaineakkuun ilman lämmön regenerointia.As new technological advances are made the importance of energy efficiency and cost effective solutions are even more important when designing and producing new machine systems. Hydraulic systems offer great performance in different actuators, but the general efficiency of the whole hydraulic systems is usually low. Energy efficiency can be improved by utilizing energy recovery systems. With energy recovery some of the normally wasted energy can be recovered and used in the next work cycle. Hydraulic energy recovery systems usually store energy in hydraulic pressure accumulators. Within the hydraulic pressure accumulator, energy is stored by compressing gas inside the accumulator’s gas volume. When compressing gas, heat builds up within the gas and temperature difference between the gas and its surroundings causes heat energy to flow out of the gas. This energy flow is the single most significant factor lowering energy efficiency of the accumulator. The goal of this study was to increase the efficiency of piston type hydraulic pressure accumulator by utilizing heat regeneration. With heat regeneration, heat energy that is generated in the gas during compression cycle is stored in the heat regenerator to be released during the following decompression cycle. Heat regenerator designed in this study utilizes phase change materials to store heat energy. Phase change materials absorb a lot of energy during phase change and thus they are commonly used as heat storages. The results obtained in this study indicate that the dynamic properties of the heat regenerator are more important than the capability to store heat energy. Low dynamic properties prevent the heat regenerator from storing and releasing energy effectively during fast compression and decompression cycles. With the heat regenerator designed in this study the energy efficiency of the accumulator increased by maximum of 3 percentage units when compared to the same accumulator without heat regeneration

    Metal Ions and Infectious Diseases. An Overview from the Clinic

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    Why People Drink Shampoo? Food Imitating Products Are Fooling Brains and Endangering Consumers for Marketing Purposes

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