ANTIOXIDANT ACTIVITY OF METHANOLIC EXTRACT OF LEAVES OF LEUCAS ZEYLANICA LINN BY USING ISOLATED FROG HEART

Objective: The present study was aimed to evaluate the antioxidant activity of methanolic extract of leaves of Leucas zeylanica Linn. by using isolated frog heart as a model.Method: 1mM  of H2O2 solution in frog Ringer solution was used to induce oxidative stress on isolated frog heart. When ringer solution containing H2O2 perfused to frog heart  preparation, which indicating the induction of oxidative stress on frog heart, this might be due to desitilization of receptors. Cardiac output, heart rate and cardiac arrest parameters were estimated.Results: The present study results supports that the frog heart model for induction of oxidative stress by H2O2. It shows negative ionotropic and chronotopic effects and the cardiac arrest was produced at 20th minute. In the presence of methanolic extract of leaves of Leucas zeylanica,  the cardiac arrest was observed at  38th minutes i.e. heart was protected longer period that indicates antioxidant activity which was compared with the standard ascorbic acid.                                  Conclusion: The results obtained in this work showed that methanolic extract of leaves of  Leucas zeylanica exhibits anti-oxidant activity against H2O2 induced oxidative stress on isolated frog heart model and compared with a standard antioxidant agent (Ascorbic acid). Key words: Frog heart, antioxidant activity, Leucas zeylanica, methanolic extract, oxidative stress

A New Technique to find the effect of Active Power Loading on Voltage Stability and Algorithm to improve Voltage Stability of Radial and Meshed Power Systems

This paper will analyze the impact of active power on voltage stability of radial and meshed systems and a new algorithm is proposed which would indicate the amount and location at which the active power is to be reduced to improve the voltage stability of entire power system or set of buses that are prone to voltage instability. A new sensitivity matrix named Active Power L-Index sensitivity matrix is been proposed. The proposed approach is simple and easy to be implemented into large power systems. The proposed approach has been applied to several Indian rural distribution networks and IEEE 14-bus test system which demonstrated applicability of the proposed approach. Index Terms- L-index matrix, Jacobian matrix, sensitivity, Active Power L-Index sensitivity matri

ECHOING SCHEME TO MAINTAIN AN GAZE AT DRIVING

The primary aim would be to provide awareness and safety mechanism for that driver. Primary reason of the accident is a result of drinking and abnormal pulse rate of driving person. Additionally for this thievery recognition, home security system and person level identification is decided. The primary utilization of human level identification technique is to recognize the individual within the vehicle. Passive infrared sensor can be used this detects a person’s level. Within this paper alcohol recognition and heartbeat monitoring system, person level identification system, accident alert, thievery recognition and mobile free auto reply technique is accustomed to avoid any sort of accident. Assume motor as engine. To begin engine user needs to send SMS from mobile. Within this project we're using LPC2148 is primary controller. It is associated with ARM7 architecture. GSM modem is linked to controller through serial interface. IR sensor, smoke sensor (MQ2), Heartbeat sensors are linked to controller through digital I/O lines. Motor also associated with H-bridge or relay. Accidents mainly occur because of driver negligence. Their simulation output is observed by LABVIEW or MATLAB and also the hardware module is acquired.  Hardware module for hybrid driver safety product is acquired with three methods namely alcohol recognition, heartbeat monitoring system, person level identification method, eye blink sensor and thievery identification. Password authentication, calls divert method, pulse level mechanism is processed. Both ways can be used to rectify the negligence from the driver and immediate intimation strategy is produced by utilization of GSM technology

Anti diabetic effect of ethanolic extract of leaves of Ocimum sanctum in alloxan induced diabetes in rats

Background: Diabetes mellitus refers to a group of common metabolic disorders that share the phenotype of hyperglycemia resulting from defects of reduced insulin secretion, decreased glucose utilization and increase in glucose production. It is estimated that there are currently 285 million people worldwide and this number is set to increase to 438 million by the year 2030. India has the highest number of patients with known diabetes worldwide, with a prevalence of 11.6%. The aim of the study was to evaluate the anti diabetic activity of ethanolic extract of leaves of plant Ocimum sanctum in alloxan induced diabetes in rats.Methods: The study was conducted on 4 groups of 6 rats each to evaluate the hypoglycaemic effect of ethanolic extract of Ocimum sanctum. Glibenclamide was used as a standard drug and the results were compared in reference to it. Tween 80 was given for both normal and diabetic control groups. The fasting blood sugar levels were recorded on 1st, 3rd, 5th, 7th, 10th days by glucometer.Results: The results indicate that the test compound ethanolic extract of Ocimum sanctum has significant and sustained oral hypoglycaemic activity, comparable with the hypoglycaemic effect of glibenclamide, a sulfonylurea.Conclusion: The hypoglycaemic potential of the test compound is found to be comparable with that of the standard drug glibenclamide

abd-A Regulation by the iab-8 Noncoding RNA

The homeotic genes in Drosophila melanogaster are aligned on the chromosome in the order of the body segments that they affect. The genes affecting the more posterior segments repress the more anterior genes. This posterior dominance rule must be qualified in the case of abdominal-A (abd-A) repression by Abdominal-B (Abd-B). Animals lacking Abd-B show ectopic expression of abd-A in the epidermis of the eighth abdominal segment, but not in the central nervous system. Repression in these neuronal cells is accomplished by a 92 kb noncoding RNA. This “iab-8 RNA” produces a micro RNA to repress abd-A, but also has a second, redundant repression mechanism that acts only “in cis.” Transcriptional interference with the abd-A promoter is the most likely mechanism

A New Approach to Cluster Datasets without Prior Knowledge of Number of Clusters

261-264The paper discusses yet another approach of clustering datasets whose cluster numbers are not known beforehand. The suggested approach effectively determines the number of clusters or partitions while running the algorithm. The proposed method is only limited to partitional clustering inspired from the K-means algorithm. In this work a Modified Teaching-Learning-Based Optimization (MTLBO) is used to form the clusters and determine the number of clusters on the run. The comparison of the results obtained by MTLBO is done with the classical TLBO and Classical Differential Evolution (DE) technique. The results show that MTLBO gives better accuracy than the other two with respect to the number of function evaluations and cluster validity measures. Several benchmark datasets are simulated from the UCI machine repository and results are tabulated in the paper

Influence of Potassium, Secondary (Mg) and Micronutrients (Zn & B) on Growth, Yield Attributes and Yield of Bt -Cotton

A field experiment was conducted to study the influence of potassium fertilization (K @0, K @60 and K @ 90 kg ha-1) and secondary (Magnesium) and micro nutrients (Zinc and Boron) on growth and yield parameters and yield of cotton hybrid Bt (MRC 7201 BGII) at Hyderabad, India during 2015-16 and 2016-17. The experiment was laid out in a split plot design with three main treatments and eight sub treatments and replicated thrice. Among the potassium levels, K @ 90 kg ha-1 recorded significantly higher plant height (76.86, 106.13 cm), number of seeds per boll (30.3, 30.9), seed cotton yield (1941, 2591 kg ha-1) and stalk yield (1967, 2755 kg ha-1) during 2015 and 2016. Among secondary (Magnesium) and micro nutrients (Zinc and Boron), Mg1%Zn0.5%B0.1% recorded highest plant height (74.65, 102.80 cm), dry weight (221.39, 243.54 g), number of seeds per boll (29.27, 29.87), seed cotton yield (1941, 2591 kg ha-1) and stalk yield (1967, 2755 kg ha-1) during 2015 and 2016