Some digenetic trematodes found in a loggerhead sea turtle (Caretta caretta) from Brazil

Research Areas: Parasitology ; ZoologyThis paper reports three recovered species of digeneans from an adult loggerhead sea turtle - Caretta caretta (Testudines, Cheloniidae) in Brazil. These trematodes include Diaschistorchis pandus (Pronocephalidae), Cymatocarpus solearis (Brachycoeliidae) and Rhytidodes gelatinosus (Rhytidodidae) The fi rst two represent new geographic records. A list of helminths reported from the Neotropical region, Gulf of Mexico and USA (Florida) is presented.info:eu-repo/semantics/publishedVersio

Coupling production networks and regional assets in manufacturing clusters

Paradoxically, the ongoing process of globalisation goes hand in hand with a surge of interest in the ‘local’ sources of firm competitiveness. In this paper, we develop a frame of analysis that helps to understand ‘coupling’ of production networks and regional development. Our aim is to reflect on the ‘spatiality’ of different types of networks, and to study the dynamic coupling process between these networks and regional assets. We apply the framework to two case studies – shipbuilding in Turku and machine building in Porto. Our analysis points towards the relevance of regional assets facilitating this coupling process and in strengthening regions as magnets for global production networks, reinforcing the long term sustainability of different types of clusters

Knowledge Locations in Cities: Emergence and Development Dynamics

This thesis studies the development of knowledge locations: area-based initiatives aimed at agglomerating knowledge-intensive activities in a designated area or city district (e.g. technology parks, creative “factories”). It relates the reinvigorated interest (and qualitative change) in knowledge locations with a number of societal evolutions, and develops a theoretical framework to explain their emergence and development. This framework contributes to better ground the study of knowledge locations within the spatial-economic context and dynamics of its host cities and regions. This study also explores the relation between a knowledge location´s features – Specialization, Urban-spatial integration and Management – and their agglomeration outcomes. It shows that there are multiple pathways to growth and agglomeration: no single factor has to be always present to explain it at a certain moment in time. Moreover, the three factors proved relevant but in different ways, and namely to the extent that they contribute to image formation (associated with the identification of a concept) and ecosystem formation (associated with exchange and learning among tenants). Those processes provide two different paths to agglomeration. Their interaction influences the development of a knowledge location over time and, ultimately, the relation between the location and change in its spatial-economic context. The abovementioned phenomena are explored with the support of four European case studies of “themed” knowledge locations, focusing on audiovisual, biotechnology, design and digital media, respectively

Regional knowledge base and firms´ exploration and exploitation: a multilevel approach

How and why do firms interact with and benefit from regionally based sources of knowledge? Although firms increasingly search and source knowledge worldwide and many are inserted in global production and knowledge networks, there is a refreshed interest in the economic geography literature on the interplay between firms´ innovative efforts and regional specific assets. Combining insights from management studies and economic geography, the article presents and explores a theoretical framework linking regionally based knowledge assets with exploration and exploitation efforts of firms, which are increasingly achieved through collaborative networks. The paper argues that the potential of firms to benefit from those localized assets is dependent on the interplay between two moderator effects: firm absorptive capacity, at the firm level, and institutional and organizational infrastructure, at the regional level

Anticardiolipin Antibody In Recurrent Spontaneous Aborting And Fertile Women.

OBJECTIVE: To determine the association between the presence of anticardiolipin antibody and a history of recurrent spontaneous abortion. STUDY DESIGN: Clinical controlled study. LOCATION: Department of Gynecology and Obstetrics-University of Campinas (UNICAMP). SUBJECTS: 52 individuals with recurrent spontaneous abortion were included in Group 1 and 104 individuals with at least one live born child in Group 2. Elapsed time from last delivery to blood sampling varied from six months to two years. METHOD: Between November 1993 and November 1994, patients' blood samples were screened for anticardiolipin antibody by ELISA, as described by Triplett, Barna and Unger (1993). ANALYSIS: Chi-square and Fisher's Exact tests were used for statistical analysis. Student's "t" test was used to compare the means. RESULTS: There was no statistical difference in the presence of the anticardiolipin antibody between Group 1 (zero and 2.9%) and Group 2 (7.7 and 5.8%). CONCLUSION: There was no association between the presence of anticardiolipin antibody and recurrent spontaneous abortion.11641760176

Classical self-forces in a space with a dispiration

We derive the gravitational and electrostatic self-energies of a particle at rest in the background of a cosmic dispiration (topological defect), finding that the particle may experience potential steps, well potentials or potential barriers depending on the nature of the interaction and also on certain properties of the defect. The results may turn out to be useful in cosmology and condensed matter physics.Comment: 5 pages, 4 figures, revtex4 fil

Iis - Integrated Interactome System: A Web-based Platform For The Annotation, Analysis And Visualization Of Protein-metabolite-gene-drug Interactions By Integrating A Variety Of Data Sources And Tools

Background: High-throughput screening of physical, genetic and chemical-genetic interactions brings important perspectives in the Systems Biology field, as the analysis of these interactions provides new insights into protein/gene function, cellular metabolic variations and the validation of therapeutic targets and drug design. However, such analysis depends on a pipeline connecting different tools that can automatically integrate data from diverse sources and result in a more comprehensive dataset that can be properly interpreted. Results: We describe here the Integrated Interactome System (IIS), an integrative platform with a web-based interface for the annotation, analysis and visualization of the interaction profiles of proteins/genes, metabolites and drugs of interest. IIS works in four connected modules: (i) Submission module, which receives raw data derived from Sanger sequencing (e.g. two-hybrid system); (ii) Search module, which enables the user to search for the processed reads to be assembled into contigs/singlets, or for lists of proteins/genes, metabolites and drugs of interest, and add them to the project; (iii) Annotation module, which assigns annotations from several databases for the contigs/singlets or lists of proteins/genes, generating tables with automatic annotation that can be manually curated; and (iv) Interactome module, which maps the contigs/singlets or the uploaded lists to entries in our integrated database, building networks that gather novel identified interactions, protein and metabolite expression/concentration levels, subcellular localization and computed topological metrics, GO biological processes and KEGG pathways enrichment. This module generates a XGMML file that can be imported into Cytoscape or be visualized directly on the web. Conclusions: We have developed IIS by the integration of diverse databases following the need of appropriate tools for a systematic analysis of physical, genetic and chemical-genetic interactions. IIS was validated with yeast two-hybrid, proteomics and metabolomics datasets, but it is also extendable to other datasets. 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Recomendações Para O Tratamento Da Crise Migranosa - Um Consenso Brasileiro

In this article, a group of experts in headache management of the Brazilian Headache Society developed through a consensus strategic measurements to treat a migraine attack in both the child and the adult. Particular emphasis was laid on the treatment of migraine in women, including at pregnancy, lactation and perimenstrual period. © 2016, Associacao Arquivos de Neuro-Psiquiatria. All rights reserved.74326227

Sensor based on β - NiOx hybrid film/multi-walled carbon nanotubes composite electrode for groundwater salinization inspection

The enrichment of groundwater with different nutrients (Na+, Ca2+, Mg2+, Cl−, CO32−, among others) triggers the salinization of the aquifer and makes it inappropriate for many purposes. In this work, we developed a highly sensitive and selective electrochemical sensor, based on Ni-inorganic films electrosynthetized in situ onto multi-walled carbon nanotubes composite paste electrode (MWCNE), which allows the early detection of salinization. The working sensor (β-NiOx/MWCNE) was derivatized from nickel hexacyanoferrate modified electrode in strong alkaline medium (pH = 12), producing a hybrid film composed by β-Ni(OH)2 and β-NiO(OH). The electrochemical properties, morphology and chemical composition of the formed β-NiOx thin films were evaluated by voltammetry, scanning electron microscopy and X-ray spectroscopy. The developed β-NiOx/MWCNE sensor was highly sensitive to the presence of Na+ cation by ion-exchange, and the increase of Na+ concentration in the range 4.46 × 10−7 to 4.93 × 10−6 mol L−1 inhibited linearly the reversible electrochemical signal of the device, allowing to determine trace concentrations of this ion (LOD = 9.86 × 10−8 mol L−1) with high correlation coefficient of the data (r = 0.999) and suitable precision/reproducibility of the measurements (RSD < 9%). Using Na+ as salinization marker and β-NiOx/MWCNE as electroanalytical device, we found evidences of groundwater salinization in Grossos, a Brazil coast city, whose inhabitants have hypertension above the national average. The attained results were comparable to those obtained by the standard methods for Na+ analysis (percentage error ranging from 0.5 to 1.6%), confirming the accuracy of the proposed electroanalytical platform.info:eu-repo/semantics/publishedVersio

Reliability and validity of a questionnaire for physical activity assessment in South American children and adolescents: The SAYCARE Study

ABSTRACT: The objective of this article is to test the reliability and validity of the new and innovative physical activity (PA) questionnaire. Methods: Subsamples from the South American Youth/Child Cardiovascular and Environment Study (SAYCARE) study were included to examine its reliability (children: n 5 161; adolescents: n 5 177) and validity (children: n 5 82; adolescents: n 5 60). The questionnaire consists of three dimensions of PA (lei-sure, active commuting, and school) performed during the last week. To assess its validity, the subjects wore accelerometers for at least 3 days and 8 h/d (at least one weekend day). The reliability was analyzed by correlation coefficients. In addition, Bland-Altman analysis and a multilevel regression were applied to estimate the measurement bias, limits of agreement, and influence of contextual variables. Results: In children, the questionnaire showed consistent reliability (q 5 0.56) and moderate validity (q 5 0.46), and the contextual variable variance explained 43.0% with 222.9 min/d bias. In adolescents, the reliability was higher (q 5 0.76) and the validity was almost excellent (q 5 0.88), with 66.7% of the variance explained by city level with 16.0 min/d PA bias. Conclusions: The SAYCARE PA questionnaire shows acceptable (in children) to strong (in adolescents) reliability and strong validity in the measurement of PA in the pediatric population from low- to middle-income countries