275 research outputs found
Integrin activation - the importance of a positive feedback
Integrins mediate cell adhesion and are essential receptors for the
development and functioning of multicellular organisms. Integrin activation is
known to require both ligand and talin binding and to correlate with cluster
formation but the activation mechanism and precise roles of these processes are
not yet resolved. Here mathematical modeling, with known experimental
parameters, is used to show that the binding of a stabilizing factor, such as
talin, is alone insufficient to enable ligand-dependent integrin activation for
all observed conditions; an additional positive feedback is required.Comment: in press in Bulletin of Mathematical Biolog
A purely algebraic construction of a gauge and renormalization group invariant scalar glueball operator
This paper presents a complete algebraic proof of the renormalizability of
the gauge invariant operator to all orders of
perturbation theory in pure Yang-Mills gauge theory, whereby working in the
Landau gauge. This renormalization is far from being trivial as mixing occurs
with other gauge variant operators, which we identify explicitly. We
determine the mixing matrix to all orders in perturbation theory by using
only algebraic arguments and consequently we can uncover a renormalization
group invariant by using the anomalous dimension matrix derived from
. We also present a future plan for calculating the mass of the lightest
scalar glueball with the help of the framework we have set up.Comment: 17 page
Learning Objects, Learning Objectives and Learning Design.
Educational research and development into e-learning mainly focuses on the inclusion of new technological features without taking into account psycho-pedagogical concerns that are likely to improve a learner's cognitive process in this new educational category. This paper presents an instructional model that combines objectivist and constructivist learning theories. The model is based on the concept of a learning objective which is composed of a set of learning objects. A software tool, called the Instruction Aid System (IAS), has been developed to guide instructors through the development of learning objectives and the execution of the analysis and design phases of the proposed instructional model. Additionally, a blended approach to the learning process in Web-based distance education is also presented. This approach combines various event-based activities: self-paced learning, live e-learning and the use of face-to-face contact in classrooms
Tensor Correlations Measured in 3He(e,e'pp)n
We have measured the 3He(e,e'pp)n reaction at an incident energy of 4.7 GeV
over a wide kinematic range. We identified spectator correlated pp and pn
nucleon pairs using kinematic cuts and measured their relative and total
momentum distributions. This is the first measurement of the ratio of pp to pn
pairs as a function of pair total momentum, . For pair relative
momenta between 0.3 and 0.5 GeV/c, the ratio is very small at low and
rises to approximately 0.5 at large . This shows the dominance of
tensor over central correlations at this relative momentum.Comment: 4 pages, 4 figures, submitted to PR
Deep exclusive electroproduction off the proton at CLAS
The exclusive electroproduction of above the resonance region was
studied using the Large Acceptance Spectrometer () at
Jefferson Laboratory by scattering a 6 GeV continuous electron beam off a
hydrogen target. The large acceptance and good resolution of ,
together with the high luminosity, allowed us to measure the cross section for
the process in 140 (, , ) bins:
, 1.6 GeV GeV and 0.1 GeV
GeV. For most bins, the statistical accuracy is on the order of a few
percent. Differential cross sections are compared to two theoretical models,
based either on hadronic (Regge phenomenology) or on partonic (handbag diagram)
degrees of freedom. Both can describe the gross features of the data reasonably
well, but differ strongly in their ingredients. If the handbag approach can be
validated in this kinematical region, our data contain the interesting
potential to experimentally access transversity Generalized Parton
Distributions.Comment: 18pages, 21figures,2table
Observation of exclusive DVCS in polarized electron beam asymmetry measurements
We report the first results of the beam spin asymmetry measured in the
reaction e + p -> e + p + gamma at a beam energy of 4.25 GeV. A large asymmetry
with a sin(phi) modulation is observed, as predicted for the interference term
of Deeply Virtual Compton Scattering and the Bethe-Heitler process. The
amplitude of this modulation is alpha = 0.202 +/- 0.028. In leading-order and
leading-twist pQCD, the alpha is directly proportional to the imaginary part of
the DVCS amplitude.Comment: 6 pages, 5 figure
A Bayesian analysis of pentaquark signals from CLAS data
We examine the results of two measurements by the CLAS collaboration, one of
which claimed evidence for a pentaquark, whilst the other found no
such evidence. The unique feature of these two experiments was that they were
performed with the same experimental setup. Using a Bayesian analysis we find
that the results of the two experiments are in fact compatible with each other,
but that the first measurement did not contain sufficient information to
determine unambiguously the existence of a . Further, we suggest a
means by which the existence of a new candidate particle can be tested in a
rigorous manner.Comment: 5 pages, 3 figure
Electron Scattering From High-Momentum Neutrons in Deuterium
We report results from an experiment measuring the semi-inclusive reaction
where the proton is moving at a large angle relative to the
momentum transfer. If we assume that the proton was a spectator to the reaction
taking place on the neutron in deuterium, the initial state of that neutron can
be inferred. This method, known as spectator tagging, can be used to study
electron scattering from high-momentum (off-shell) neutrons in deuterium. The
data were taken with a 5.765 GeV electron beam on a deuterium target in
Jefferson Laboratory's Hall B, using the CLAS detector. A reduced cross section
was extracted for different values of final-state missing mass ,
backward proton momentum and momentum transfer . The data
are compared to a simple PWIA spectator model. A strong enhancement in the data
observed at transverse kinematics is not reproduced by the PWIA model. This
enhancement can likely be associated with the contribution of final state
interactions (FSI) that were not incorporated into the model. A ``bound neutron
structure function'' was extracted as a function of and
the scaling variable at extreme backward kinematics, where effects of
FSI appear to be smaller. For MeV/c, where the neutron is far
off-shell, the model overestimates the value of in the region of
between 0.25 and 0.6. A modification of the bound neutron structure
function is one of possible effects that can cause the observed deviation.Comment: 33 pages RevTeX, 9 figures, to be submitted to Phys. Rev. C. Fixed 1
Referenc
Complete measurement of three-body photodisintegration of 3He for photon energies between 0.35 and 1.55 GeV
The three-body photodisintegration of 3He has been measured with the CLAS
detector at Jefferson Lab, using tagged photons of energies between 0.35 GeV
and 1.55 GeV. The large acceptance of the spectrometer allowed us for the first
time to cover a wide momentum and angular range for the two outgoing protons.
Three kinematic regions dominated by either two- or three-body contributions
have been distinguished and analyzed. The measured cross sections have been
compared with results of a theoretical model, which, in certain kinematic
ranges, have been found to be in reasonable agreement with the data.Comment: 22 pages, 25 eps figures, 2 tables, submitted to PRC. Modifications:
removed 2 figures, improvements on others, a few minor modifications to the
tex
A Kinematically Complete Measurement of the Proton Structure Function F2 in the Resonance Region and Evaluation of Its Moments
We measured the inclusive electron-proton cross section in the nucleon
resonance region (W < 2.5 GeV) at momentum transfers Q**2 below 4.5 (GeV/c)**2
with the CLAS detector. The large acceptance of CLAS allowed for the first time
the measurement of the cross section in a large, contiguous two-dimensional
range of Q**2 and x, making it possible to perform an integration of the data
at fixed Q**2 over the whole significant x-interval. From these data we
extracted the structure function F2 and, by including other world data, we
studied the Q**2 evolution of its moments, Mn(Q**2), in order to estimate
higher twist contributions. The small statistical and systematic uncertainties
of the CLAS data allow a precise extraction of the higher twists and demand
significant improvements in theoretical predictions for a meaningful comparison
with new experimental results.Comment: revtex4 18 pp., 12 figure
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