86 research outputs found
Evaluation of sweetpotato (Ipomoea batatas (L.) Lam.) germplasm from north-eastern Uganda through a Farmer Participatory Approach
Ugandan farmers grow many landrace sweetpotato varieties, but some of these are relatively low yielding and susceptible to pests. The objective of the present research was to involve farmers in a large-scale assessment of Ugandan farmers’ varieties to rapidly identify those with superior yield performance, pest resistance and consumer acceptance. One hundred sixty distinct farmers’ varieties collected from Lira, Soroti, Katakwi, Kumi and Pallisa Districts of North-eastern Uganda were evaluated in on-station trials. Trials were conducted at two sites (Serere Agricultural and Animal Research Institute and Arapai Agricultural College) in Soroti District in the second rainy season of 1999. Twenty-five farmers from surrounding areas participated in trial harvest at each site. At harvest, fresh storage root yield, foliage yield, and dry matter content were determined by researchers. Farmers observed a number of characteristics and rated each entry with respect to the following variables: general impression, dry matter content, pests, and defects. A strong positive correlation was observed between farmers’ general impression and yield and harvest index in the trials. Farmers selected 10 superior varieties from each trial for further multi-environment, on-station and on-farm trials. Coincidentally, nine of the selected varieties were common to both sites
On unbounded p-summable Fredholm modules
We prove that odd unbounded p-summable Fredholm modules are also bounded
p-summable Fredholm modules (this is the odd counterpart of a result of A.
Connes for the case of even Fredholm modules)
Functional Integral Construction of the Thirring model: axioms verification and massless limit
We construct a QFT for the Thirring model for any value of the mass in a
functional integral approach, by proving that a set of Grassmann integrals
converges, as the cutoffs are removed and for a proper choice of the bare
parameters, to a set of Schwinger functions verifying the Osterwalder-Schrader
axioms. The corresponding Ward Identities have anomalies which are not linear
in the coupling and which violate the anomaly non-renormalization property.
Additional anomalies are present in the closed equation for the interacting
propagator, obtained by combining a Schwinger-Dyson equation with Ward
Identities.Comment: 55 pages, 9 figure
Correlation-Polarization Effects in Electron/Positron Scattering from Acetylene: A Comparison of Computational Models
Different computational methods are employed to evaluate elastic
(rotationally summed) integral and differential cross sections for low energy
(below about 10 eV) positron scattering off gas-phase CH molecules. The
computations are carried out at the static and static-plus-polarization levels
for describing the interaction forces and the correlation-polarization
contributions are found to be an essential component for the correct
description of low-energy cross section behavior. The local model potentials
derived from density functional theory (DFT) and from the distributed positron
model (DPM) are found to produce very high-quality agreement with existing
measurements. On the other hand, the less satisfactory agreement between the
R-matrix (RM) results and measured data shows the effects of the slow
convergence rate of configuration-interaction (CI) expansion methods with
respect to the size of the CI-expansion. To contrast the positron scattering
findings, results for electron-CH integral and differential cross
sections, calculated with both a DFT model potential and the R-matrix method,
are compared and analysed around the shape resonance energy region and found to
produce better internal agreement
The evolving SARS-CoV-2 epidemic in Africa: Insights from rapidly expanding genomic surveillance
INTRODUCTION
Investment in Africa over the past year with regard to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) sequencing has led to a massive increase in the number of sequences, which, to date, exceeds 100,000 sequences generated to track the pandemic on the continent. These sequences have profoundly affected how public health officials in Africa have navigated the COVID-19 pandemic.
RATIONALE
We demonstrate how the first 100,000 SARS-CoV-2 sequences from Africa have helped monitor the epidemic on the continent, how genomic surveillance expanded over the course of the pandemic, and how we adapted our sequencing methods to deal with an evolving virus. Finally, we also examine how viral lineages have spread across the continent in a phylogeographic framework to gain insights into the underlying temporal and spatial transmission dynamics for several variants of concern (VOCs).
RESULTS
Our results indicate that the number of countries in Africa that can sequence the virus within their own borders is growing and that this is coupled with a shorter turnaround time from the time of sampling to sequence submission. Ongoing evolution necessitated the continual updating of primer sets, and, as a result, eight primer sets were designed in tandem with viral evolution and used to ensure effective sequencing of the virus. The pandemic unfolded through multiple waves of infection that were each driven by distinct genetic lineages, with B.1-like ancestral strains associated with the first pandemic wave of infections in 2020. Successive waves on the continent were fueled by different VOCs, with Alpha and Beta cocirculating in distinct spatial patterns during the second wave and Delta and Omicron affecting the whole continent during the third and fourth waves, respectively. Phylogeographic reconstruction points toward distinct differences in viral importation and exportation patterns associated with the Alpha, Beta, Delta, and Omicron variants and subvariants, when considering both Africa versus the rest of the world and viral dissemination within the continent. Our epidemiological and phylogenetic inferences therefore underscore the heterogeneous nature of the pandemic on the continent and highlight key insights and challenges, for instance, recognizing the limitations of low testing proportions. We also highlight the early warning capacity that genomic surveillance in Africa has had for the rest of the world with the detection of new lineages and variants, the most recent being the characterization of various Omicron subvariants.
CONCLUSION
Sustained investment for diagnostics and genomic surveillance in Africa is needed as the virus continues to evolve. This is important not only to help combat SARS-CoV-2 on the continent but also because it can be used as a platform to help address the many emerging and reemerging infectious disease threats in Africa. In particular, capacity building for local sequencing within countries or within the continent should be prioritized because this is generally associated with shorter turnaround times, providing the most benefit to local public health authorities tasked with pandemic response and mitigation and allowing for the fastest reaction to localized outbreaks. These investments are crucial for pandemic preparedness and response and will serve the health of the continent well into the 21st century
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