An extraordinary testimonial of thermal rehabilitation: Giuseppe Garibaldi - 2011: 150th Anniversary of the Italian Unification

On the occasion of the 150th Anniversary of the Italian Unification, the discovery of some letters by Giuseppe Garibaldi - referring to a period of thermal treatments at the Baths in Civitavecchia (Rome) - gave us the opportunity for writing a commentary about a not well known experience in the Two World Hero's life: the numerous treatments carried out at many Italian spa centres for treating a rheumatic pathology (probably a rheumatoid polyarthritis) and the outcomes of various war wounds, especially the famous gunshot-wound in his right ankle during the Battle of Aspromonte, in 1862

Mind the gap! Organized hypocrisy in EU cooperation with Southern neighbor countries on international protection

The European Union (EU) has reacted to the migration crises of the last decade with growing externalization of migration management to neighbor countries often accused of not respecting human rights and individual liberties. Focusing on EU cooperation with the Southern neighborhood, as defined within the European Neighborhood Policy (ENP) framework, this paper investigates the recent developments in the EU's external migration policies, demonstrating that there is a gap between EU discourses and policy instruments identified by the EU as strategic tools of the European migration and asylum policy (MAP). Five Southern neighbor countries (SNCs) have been selected, Tunisia, Morocco, Egypt, Jordan, and Lebanon, to assess the extent to which the EU, when cooperating on migration and asylum issues, places international protection at risk instead of playing the role of humanitarian actor in accordance with the ideals and principles it defends. The research critically analyzes the EU's cooperation with SNCs concerning migration, as developed via international agreements, action plans, and mobility partnerships under the umbrella of the ENP. In particular, it explores the incompatibility between the European MAP instruments and international protection. MAP, the qualitative analysis shows, represents a clear mismatch between EU talk and action, outlining another case of organized hypocrisy

Tutori, ortesi, protesi, ausili. Testo-Atlante per le Professioni dell'Area Sanitaria

“... un testo aggiornato, completo e di rapida consultazione per comprendere indicazioni e modalità di utilizzo di tutori, ortesi, protesi e ausili; una iconografia dettagliata che consente di visualizzare immediatamente forma e impiego degli stessi...” (dalla prefazione del Prof. Giulio Maccauro) Un testo-atlante che non esaurisce la sua funzione didattica al termine del corso di studi, ma che rimane come utile e maneggevole strumento di consultazione e di formazione nella pratica quotidiana di qualsiasi Professionista dell’Area Sanitaria. Con 164 figure a colori. Maggiori dettagli nel PDF scaricabile (indice, prefazione completa, pagine campione) e sul sito dell’editore UniversItalia.Braces, orthoses, prostheses, assistive devices. Text-Atlas for Healthcare Professionals "... an updated, complete and quick reference text to understand indications and methods of use of braces, orthoses, prostheses and assistive devices; a detailed iconography that allows you to immediately visualize their form and use..." (from the preface by Prof. Giulio Maccauro) A text-atlas that does not exhaust its didactic function at the end of the course of study but remains a useful and handy tool for consultation and training in the daily practice of any Healthcare Professional. With 164 colour figures. Further details in the downloadable PDF (index, full preface, sample pages) and on the website of the publisher UniversItalia

Predicting LVOT Obstruction in Transcatheter Mitral Valve Replacement for Failed Surgical Annuloplasty

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Effect of long term dietary supplementation with plant extract on carcass characteristics meat quality and oxidative stability in pork

Abstract The effects of dietary supplementation in pigs with plant extract (PE) from Lippia spp., titrated in verbascoside (5 mg/kg feed), from weaning to slaughter (166 days), on carcass characteristics, meat quality, collagen characteristics, oxidative stability and sensory attributes of Longissimus dorsi (LD) muscle were examined. Ten pigs per treatment were slaughter at a live weight of 109.5 ± 1.4 kg. No influence on carcass characteristics, LD meat quality parameters and collagen characteristics were observed. Dietary PE increased (

Medicina Fisica e Riabilitativa: nuovi aspetti di una disciplina di interesse per la Medicina Generale

La Medicina Fisica e Riabilitativa (MFR) è una disciplina medico-specialistica con compiti assistenziali, didattici e di ricerca per la prevenzione, la valutazione e il trattamento delle disabilità conseguenti a malattie di origine congenita o acquisita. La caratteristica della MFR non è quella di guarire la malattia, compito delle tradizionali discipline d’organo, bensì quello di curare il malato, nella sua unicità e specificità. La MFR viene spesso definita la “professione della qualità di vita”, che mira a migliorare in tutti i suoi aspetti: medico, sociale, emozionale, lavorativo

Interplay between Tectonics and Mount Etna’s Volcanism: Insights into the Geometry of the Plumbing System

Mt. Etna lies in front of the southeast-verging Apennine-Maghrebian fold-and-thrust belt, where the NNW-trending Malta Escarpment separates the Sicilian continental crust from the Ionian Mesozoic oceanic basin, presently subducting beneath the Calabrian arc (Selvaggi and Chiarabba, 1995). Seismic tomographic studies indicate the presence of a mantle plume beneath the volcano with a Moho transition at depth less than 20 km (Nicolich et al.,2000; Barberi et al., 2006). Geophysical and geological evidences suggest that the Mt. Etna magma ascent mechanism is related to the major NNW-trending lithospheric fault (Doglioni et al., 2001). However, the reason for the Mt. Etna mantle plume draining and channeling the magma from the upper mantle source to the surface is not yet clear. All models proposed in literature (Rittmann, 1973; Tanguy et al., 1997; Monaco et al.; 1997; Gvirtzman and Nur, 1999; Doglioni et al., 2001) do not explain why such a mantle plume has originated in this anomalous external position with respect to the arc magmatism and back-arc spreading zones associated with the Apennines subduction. Some ideas on the subduction rollback must be better developed through the comparison with new regional tomographic studies that are being released. Moreover, tomographic studies reveal a complex and large plumbing system below the volcano from -2 to -7 km a.s.l., wide up to 60 km2 that reduces itself in size down to -18 km of depth close to the apex of the mantle plume. Chiocci et al. (2011) found a large bulge on the underwater continental margin facing Mt. Etna, and suggested that the huge crystallized magma body intruded in the middle and upper continental crust was able to trigger an instability process involving the Sicilian continental margin during the last 0.1 Ma. This phenomenon induces the sliding of the volcano eastern flank observed since the 90s (Borgia et al, 1992; Lo Giudice and Rasà, 1992) because the effects of the bulge collapse are propagating upslope, and the continuous decompression at the volcano summit favors the ascent of basic magma without lengthy storage in the upper crust, as one might expect in a compressive tectonic regime. Taken together, these new evidences (tomographic, tectonic, volcanic) are concerned with the exceptional nature of Mt. Etna and raise the need to explain the origin of the mantle plume that supplies its volcanism. The lower crust and the uppermost mantle need to be better resolved in future experiments and studies. The use of regional and teleseismic events for tomography and receiver function analyses is required to explore a volume that has only marginally been investigated to date. The relation between the magma source in the mantle and the upper parts of the system, as well as the hypothesis above reported on the relation between tectonics and volcanism and the role of lithospheric faults, could be resolved only by applying seismological techniques able to better constrain broader and deeper models. Finally, although the recent tomographic inversions have progressively improved our knowledge of Etna’s shallow structure, highlighting a complex pattern of magma chambers and conduits with variable dimensions, the geometry of the conduits and the dimensions and shapes of small magmatic bodies still require greater investigation. Their precise definition is crucial to delineate a working model of this volcano in order to understand its behaviour and evolution. For this purpose, at least within the volcanic edifice, the precise locations of the seismo-volcanic signals can be considered a useful tool to constrain both the area and the depth range of magma degassing and the geometry of the shallow conduits. In this work, we furnish evidences that the tremor and LP locations allowed to track magma migration during the initial phase of the 2008-2009 eruption and in particular the initial northward dike intrusion, also confirmed by other geophysical, structural and volcanological observations (Aloisi et al., 2009; Bonaccorso et al., 2011), and the following fissure opening east of the summit area at the base of SEC. All these evidences, obtained by the marked improvement in the monitoring system together with the development of new processing techniques, allowed us to constrain both the area and the depth range of magma degassing, highlighting the geometry of the magmatic system feeding the 2008-2009 eruption

High-density ZnO nanowires for cellular biointerfaces: a new role as myogenic differentiation switch

The design of artificial platforms for expanding undifferentiated stem cells is of tremendous importance for regenerative medicine [1]. We have recently demonstrated that a ZnO nanowires (NWs) decorated glass support permits to obtain a differentiation switch during proliferation for mesoangioblasts (MABs)– i.e. multipotent progenitor cells which are remarkable candidates for the therapy of muscle diseases [2]. We have optimized the ZnO NWs synthesis on glass surfaces by numerical simulations and experimental systematic investigations, considering zinc speciation and supersaturation [3]. In particular, we demonstrated by numerical simulations that the ligand ethylenediamine, at the isoelectric point of the ZnO NWs tips, can effectively control – at 1:1 stoichiometric ratio with zinc – both speciation and supersaturation of zinc in the nutrient solution. In this regard, we employed ethanolamine (a safer precursor) for in-situ producing ethylenediamine by means of a zinc-catalysed amination reaction of ethanolamine by ammonia. The obtained highquality ZnONWs-cells biointerface allows cells to maintain viability and a spherical viable undifferentiated state during the 8 days observation time. Simulations of the interface by theoretical models [4] and our experimental investigations by SEM and confocal microscopy demonstrate that NWs do not induce any damage on the cellular membrane, whilst blocking their differentiation. More specifically, the myosin heavy chain, typically expressed in differentiated myogenic progenitors, is completely absent. Interestingly, the differentiation capabilities are completely restored upon cell removal from the NW-functionalized substrate and regrowing onto a standard culture glass dish. These results open the way towards unprecedented applications of ZnO NWs for cell-based therapy and tissue engineering [5]. References [1] G. Cossu, P. Bianco, Curr. Opin. Genet. Dev. 2003, 13, 537-542. [2] V. Errico, G. Arrabito, E. Fornetti, C. Fuoco, S. Testa, G. Saggio, S. Rufini, S. M. Cannata, A. Desideri, C. Falconi, C. Gargioli, ACS Appl. Mater. Interfaces, 2018, 10, 14097- 14107. [3] G. Arrabito, V. Errico, Z. Zhang, W. Han, C. Falconi, Nano Energy, 2018, 46, 54-62. [4] N. Buch-Månson, S. Bonde, J. Bolinsson, T. Berthing, J. Nygård, K.L. Martinez, Adv. Funct. Mater. 2015, 25, 3246-3255. [5] Y. Su, I. Cockerill, Y. Wang, Y.-X. Qin, L. Chang, Y. Zheng, and D. Zhu, Trends in Biotechnology, 2019, 37, 428-441

Percutaneous Edge-to-Edge Mitral Valve Repair with the Mitraclip System in Barlow's Disease

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