An evaluation of enhanced geotextile layer in permeable pavement to improve stormwater infiltration and attenuation

This paper reports on an evaluation of the properties of a novel structure known as OASIS® which was designed at Coventry University as an enhancement of the commercially available geotextiles when incorporated in the permeable pavement system (PPS). The impact on the hydraulic behaviour of a PPS was analysed through the study of infiltration rate, throughout the PPS and time required to reach the steady-state stage behaviour of the water within the PPS, under extreme rainfall intensities of 100 mm/hr, 200 mm/hr and 400 mm/hr, corresponding to a 100-year return period rainfall over a duration of 15 min in different parts of the world. The result indicated that the novel structure provides an extra benefit when incorporated in PPSs, delaying peak flow of a rainfall event by retaining and storing great volumes of water within its structure. These additional benefits are especially important under extreme rainfall events

Cysteine-based 3-substituted 1, 5-benzoxathiepin derivatives: Two new classes of anti-proliferative agents

Two distinct series of the 3-amino-1, 5-benzoxathiepin scaffold, derived from L-cysteine, were synthesized and evaluated for their anti-proliferative activity in the breast cancer MDA-MB-231 and MCF-7 cells, and in the ovarian carcinoma SKOV-3 cell line. (3R)-Amino-3, 4-dihydro-2H-1, 5-benzoxathiepin [(R)-10] was diversified into two forms: (a) by incorporating different amino acids at its position 3, through an amide bond; and (b) by construction of the purine ring to give 6-chloro-9-[2-(3, 4-dihydro-2H-1, 5-benzoxathiepin-(3R)-yl)]-9H-purine [(R)-28]. Nevertheless, when the introduction of iodine was tried at position 2 of the purine ring of (R)-28, 2-{[2-(6-chloro-2-iodo-9H-purin-9-yl) prop-2-en-1-yl] thio} phenol (34) was obtained. Compound 34 shows activity against cancer cells. Interestingly, 34 inhibits mammosphere formation at the micromolar range, demonstrating activity against cancer stem cells. Although further studies of its targets and mechanism of action are needed, these findings support the therapeutic potential of this compound in cancer

Probing neutrino properties with charged scalar lepton decays

Supersymmetry with bilinear R-parity violation provides a predictive framework for neutrino masses and mixings in agreement with current neutrino oscillation data. The model leads to striking signals at future colliders through the R-parity violating decays of the lightest supersymmetric particle. Here we study charged scalar lepton decays and demonstrate that if the scalar tau is the LSP (i) it will decay within the detector, despite the smallness of the neutrino masses, (ii) the relative ratio of branching ratios Br({tilde tau}_1 --> e sum nu_i)/ Br({tilde tau}_1 --> mu sum nu_i) is predicted from the measured solar neutrino angle, and (iii) scalar muon and scalar electron decays will allow to test the consistency of the model. Thus, bilinear R-parity breaking SUSY will be testable at future colliders also in the case where the LSP is not the neutralino.Comment: 24 pages, 8 ps figs Report-no.: IFIC/02-33 and ZU-TH 11/0

Charged lepton Flavor Violation in Supersymmetry with Bilinear R-Parity Violation

The simplest unified extension of the Minimal Supersymmetric Standard Model with bi-linear R-parity violation naturally predicts a hierarchical neutrino mass spectrum, suitable to explain atmospheric and solar neutrino fluxes. We study whether the individual violation of the lepton numbers L_{e,mu,tau} in the charged sector can lead to measurable rates for BR(mu->e gamma)and $BR(tau-> mu gamma). We find that some of the R-parity violating terms that are compatible with the observed atmospheric neutrino oscillations could lead to rates for mu->e gamma measurable in projected experiments. However, the Delta m^2_{12} obtained for those parameters is too high to be compatible with the solar neutrino data, excluding therefore the possibility of having measurable rates for mu->e gamma in the model.Comment: 29 pages, 8 figures. Constraint from solar neutrino data included, conclusions changed respect v